Helen M. Arthur - Publications, H-index & Citations

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Helen M. Arthur

Newcastle University

47H-index

162Paper Count

9.0KCitation Count

Published Papers 58

Publication Date

Endoglin as a BMP9 co-receptor in vascular endothelial cells: prodomain displacement and TGFBRII recruitment

Nature Communications

IF15.7

2025-12-31

OAAI

Jingxu Guo; Karolina Kostrzyńska; Ioannis Kamzolas; Xudong Yang; Midory Thorikay; Eckart De Bie; Rowena J. Jones; Adam Brownstein; Lu Long; Christopher J. Rhodes; Allan Lawrie; Martin R. Wilkins; Esmee Groeneveld; Zhen Tong; Marie-José Goumans; Evangelia Petsalaki; Jason Hong; Mark R. Toshner; Antonio Vidal-Puig; Helen M. Arthur; Wei Li

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CDK6-mediated endothelial cell cycle acceleration drives arteriovenous malformations in hereditary hemorrhagic telangiectasia

cardiovascular research

IF10.8

2024-11-01

PREAI

Dinakaran, Sajeth; Qutaina, Sima; Zhao, Haitian; Tang, Yuefeng; Wang, Zhimin; Ruiz, Santiago; Nomura-Kitabayashi, Aya; Metz, Christine N.; Arthur, Helen M.; Meadows, Stryder M.; Blanc, Lionel; Faughnan, Marie E.; Marambaud, Philippe

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VEGFR2 Expression Correlates with Postnatal Development of Brain Arteriovenous Malformations in a Mouse Model of Type I Hereditary Hemorrhagic Telangiectasia

BIOMEDICINES

IF3.9

2023-11-27

OAAI

Han, Chul; Nguyen, Candice L.; Scherschinski, Lea; Schriber, Tyler D.; Arthur, Helen M.; Lawton, Michael T.; Oh, Suk Paul

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ANG2 Blockade Diminishes Proangiogenic Cerebrovascular Defects Associated With Models of Hereditary Hemorrhagic Telangiectasia

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

IF7.4

2023-08-01

OAAI

Zhou, Xingyan; Pucel, Jenna C.; Nomura-Kitabayashi, Aya; Chandakkar, Pallavi; Guidroz, Adella P.; Jhangiani, Nikita L.; Bao, Duran; Fan, Jia; Arthur, Helen M.; Ullmer, Christoph; Klein, Christian; Marambaud, Philippe; Meadows, Stryder M.

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INVESTIGATING THE THERAPEUTIC POTENTIAL OF RECOMBINANT BMP10 IN A MOUSE MODEL OF HEREDITARY HAEMORRHAGIC TELANGIECTASIA

HEART

IF4.4

2023-06-02

OAAI

Kostrzynska, Karolina; Yang, XuDong; Guo, Jingxu; Moore, Stephen; Morrell, Nick; Arthur, Helen M.; Li, Wei

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Therapeutic targeting of vascular malformation in a zebrafish model of hereditary haemorrhagic telangiectasia

DISEASE MODELS & MECHANISMS

IF3.3

2023-03-30

OAAI

Snodgrass, Ryan O.; Govindpani, Karan; Plant, Karen; Kugler, Elisabeth C.; Doh, Changmin; Dawson, Thomas; McCormack, Luis E.; Arthur, Helen M.; Chico, Timothy J. A.

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An update on preclinical models of hereditary haemorrhagic telangiectasia: Insights into disease mechanisms

FRONTIERS IN MEDICINE

IF3

2022-09-29

OAAI

Arthur, Helen M.; Roman, Beth L.

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INHIBITION OF VEGF SIGNALLING MITIGATES THE HEREDITARY HAEMORRHAGIC TELANGIECTASIA-LIKE PHENOTYPE IN ENDOGLIN MUTANT ZEBRAFISH

HEART

IF4.4

2021-06-04

OAAI

Snodgrass, Ryan; Chico, Tim; Arthur, Helen

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Rapid fall in circulating non-classical monocytes in ST elevation myocardial infarction patients correlates with cardiac injury

FASEB JOURNAL

IF4.2

2021-04-29

OAAI

Marsh, Sarah A.; Park, Catherine; Redgrave, Rachael E.; Singh, Esha; Draganova, Lilia; Boag, Stephen E.; Spray, Luke; Ali, Simi; Spyridopoulos, Ioakim; Arthur, Helen M.

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Report of the British Society for Cardiovascular Research Inaugural Online Autumn Meeting 2020

CARDIOVASCULAR DRUGS AND THERAPY

IF3.1

2021-03-13

OAAI

Arthur, Helen M.

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RETRACTION: Disruption of embryonic ROCK signaling reproduces the sarcomeric phenotype of hypertrophic cardiomyopathy (Retraction of Vol 4, art no E125172, 2019)

JCI INSIGHT

IF6.1

2020-12-17

OAAI

Bailey, Kate E.; MacGowan, Guy A.; Tual-Chalot, Simon; Phillips, Lauren; Mohun, Timothy J.; Henderson, Deborah J.; Arthur, Helen M.; Bamforth, Simon D.; Phillips, Helen M.

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Overexpression of Activin Receptor-Like Kinase 1 in Endothelial Cells Suppresses Development of Arteriovenous Malformations in Mouse Models of Hereditary Hemorrhagic Telangiectasia

CIRCULATION RESEARCH

IF16.2

2020-10-09

OAAI

Kim, Yong Hwan; Phuong-Nhung Vu; Choe, Se-Woon; Jeon, Chang-Jin; Arthur, Helen M.; Vary, Calvin P. H.; Lee, Young Jae; Oh, S. Paul

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Clearance of senescent cells during cardiac ischemia-reperfusion injury improves recovery

AGING CELL

IF7.1

2020-09-29

104

OAAI

Dookun, Emily; Walaszczyk, Anna; Redgrave, Rachael; Palmowski, Pawel; Tual-Chalot, Simon; Suwana, Averina; Chapman, James; Jirkovsky, Eduard; Donastorg Sosa, Leticia; Gill, Eleanor; Yausep, Oliver E.; Santin, Yohan; Mialet-Perez, Jeanne; Andrew Owens, W.; Grieve, David; Spyridopoulos, Ioakim; Taggart, Michael; Arthur, Helen M.; Passos, Joao F.; Richardson, Gavin D.

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Therapeutic Potential of Senolytics in Cardiovascular Disease

CARDIOVASCULAR DRUGS AND THERAPY

IF3.1

2020-09-26

OAAI

Dookun, Emily; Passos, Joao F.; Arthur, Helen M.; Richardson, Gavin D.

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Oncogenes in Brain Arteriovenous Malformations

CIRCULATION RESEARCH

IF16.2

2020-08-28

OAAI

Jakobsson, Lars; Arthur, Helen M.

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Arterial endoglin does not protect against arteriovenous malformations

ANGIOGENESIS

IF9.2

2020-06-06

OAAI

Singh, Esha; Redgrave, Rachael E.; Phillips, Helen; Arthur, Helen M.

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CMV-independent increase in CD27-CD28+ CD8+ EMRA T cells is inversely related to mortality in octogenarians

NPJ AGING AND MECHANISMS OF DISEASE

IF5.4

2020-01-21

OAAI

Martin-Ruiz, Carmen; Hoffmann, Jedrzej; Shmeleva, Evgeniya; von Zglinicki, Thomas; Richardson, Gavin; Draganova, Lilia; Redgrave, Rachael; Collerton, Joanna; Arthur, Helen; Keavney, Bernard; Spyridopoulos, Ioakim

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Loss of Endothelial Endoglin Promotes High-Output Heart Failure Through Peripheral Arteriovenous Shunting Driven by VEGF Signaling

CIRCULATION RESEARCH

IF16.2

2020-01-17

OAAI

Tual-Chalot, Simon; Garcia-Collado, Maria; Redgrave, Rachael E.; Singh, Esha; Davison, Benjamin; Park, Catherine; Lin, Hua; Luli, Saimir; Jin, Yi; Wang, Yixin; Lawrie, Allan; Jakobsson, Lars; Arthur, Helen M.

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Role of soluble endoglin in BMP9 signaling

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2019-08-20

OAAI

Lawera, Aleksandra; Tong, Zhen; Thorikay, Midory; Redgrave, Rachael E.; Cai, Jie; van Dinther, Maarten; Morrell, Nicholas W.; Afink, Gijs B.; Charnock-Jones, D. Stephen; Arthur, Helen M.; ten Dijke, Peter; Li, Wei

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DEVELOPMENTAL ROCK DOWNREGULATION DISRUPTS SARCOMERIC STRUCTURE RESULTING IN THE DEVELOPMENT OF HYPERTROPHIC CARDIOMYOPATHY

HEART

IF4.4

2019-05-01

OAAI

Bailey, Kate; MacGowan, Guy; Tual-Chalot, Simon; Phillips, Lauren; Mohun, Timothy J.; Henderson, Deborah J.; Arthur, Helen; Bamforth, Simon; Phillips, Helen M.

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Research Directions