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Alexander Gusev

Dana-Farber Cancer Institute and Harvard Medical School

58H-index
318Paper Count
2.4WCitation Count
Published Papers 112
Publication Date
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A Bayesian framework for longitudinal EHR and genetic discovery
errNature
IF48.5
err2026-07-15
err0
errOAAI
errSarah M. Urbut; Yi Ding; Tetsushi Nakao; Satoshi Koyama; Anika Misra; Xilin Jiang; Achyutha Harish; Leslie Gaffney; Whitney E. Hornsby; Jordan W. Smoller; Alexander Gusev; Pradeep Natarajan; Giovanni Parmigiani
errShare
errSave
Data-driven RNA phenotyping captures genetically regulated dimensions of the transcriptome
errAmerican Journal of Human Genetics
IF8.1
err2026-07-02
err0
errOAAI
errDaniel Munro; Alexander Gusev; Abraham A. Palmer; Pejman Mohammadi
errShare
errSave
Functional dissection of complex trait variants at single-nucleotide resolution
errNature
IF48.5
err2026-02-25
err0
errOAAI
errLayla Siraj; Rodrigo I. Castro; Hannah B. Dewey; Susan Kales; John C. Butts; Thanh Thanh L. Nguyen; Masahiro Kanai; Daniel Berenzy; Kousuke Mouri; Qingbo S. Wang; Petko P. Fiziev; Kristin Tsuo; Zachary R. McCaw; Sager J. Gosai; François Aguet; Ran Cui; Irfahan Kassam; Jeremy McRae; Christopher M. Vockley; Caleb A. Lareau; Sergey Abramov; Alexandr Boystov; Jeff Vierstra; Yukinori Okada; Alexander Gusev; Thouis R. Jones; Eric S. Lander; Pardis C. Sabeti; Hilary K. Finucane; Steven K. Reilly; Jacob C. Ulirsch; Ryan Tewhey
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errSave
Discovery of disease-associated cellular states using ResidPCA in single-cell RNA and ATAC sequencing data
errHuman Genetics and Genomics Advances
IF3.6
err2025-10-27
err0
errOAAI
errShaye Carver; Kodi Taraszka; Stefan Groha; Alexander Gusev
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errSave
Limited overlap between genetic effects on disease susceptibility and disease survival
errNature Genetics
IF29
err2025-09-30
err0
errOAAI
errZhiyu Yang; Fanny-Dhelia Pajuste; Kristina Zguro; Yipeng Cheng; Danielle E. Kurant; Andrea Eoli; Julian Wanner; Bradley Jermy; Joel Rämö; Stavroula Kanoni; David A. van Heel; Caroline Hayward; Riccardo E. Marioni; Daniel L. McCartney; Alessandra Renieri; Simone Furini; Reedik Mägi; Alexander Gusev; Petros Drineas; Peristera Paschou; Henrike Heyne; Samuli Ripatti; Nina Mars; Andrea Ganna
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errSave
Improved multiancestry fine-mapping identifies cis-regulatory variants underlying molecular traits and disease risk
errNature Genetics
IF0
err2025-07-21
err0
PREAI
errZeyun Lu; Xinran Wang; Matthew Carr; Artem Kim; Steven Gazal; Pejman Mohammadi; Lang Wu; James Pirruccello; Linda Kachuri; Alexander Gusev; Nicholas Mancuso
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errSave
Multimodal analysis of RNA sequencing data powers discovery of complex trait genetics
errNATURE COMMUNICATIONS
IF15.7
err2024-11-29
err0
errOAAI
errMunro, Daniel; Ehsan, Nava; Esmaeili-Fard, Seyed Mehdi; Gusev, Alexander; Palmer, Abraham A.; Mohammadi, Pejman
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errSave
Aladyn Individual: Dynamic Individual Comorbidity Modeling for Genomic Discovery and Clinical Prediction
errCIRCULATION
IF38.6
err2024-11-12
err0
PREAI
errUrbut, Sarah; Ding, Yi; Taraszka, Kodi; Yeung, Ming Wai; Patel, Aniruddh; Hornsby, Whitney; Duan, Rui; Gusev, Alexander; Parmigiani, Giovanni; Natarajan, Pradeep
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errSave
Obesity-dependent selection of driver mutations in cancer
errNATURE GENETICS
IF31.8
err2024-10-28
err0
errOAAI
errTang, Cerise; Castillon, Venise Jan; Waters, Michele; Fong, Chris; Park, Tricia; Boscenco, Sonia; Kim, Susie; Pekala, Kelly; Carrot-Zhang, Jian; Hakimi, A. Ari; Schultz, Nikolaus; Ostrovnaya, Irina; Gusev, Alexander; Jee, Justin; Reznik, Ed
errShare
errSave
Heterogeneous genetic architectures of prostate cancer susceptibility in sub-Saharan Africa
errNATURE GENETICS
IF31.8
err2024-10-02
err0
PREAI
errJanivara, Rohini; Chen, Wenlong C.; Hazra, Ujani; Baichoo, Shakuntala; Agalliu, Ilir; Kachambwa, Paidamoyo; Simonti, Corrine N.; Brown, Lyda M.; Tambe, Saanika P.; Kim, Michelle S.; Harlemon, Maxine; Jalloh, Mohamed; Muzondiwa, Dillon; Naidoo, Daphne; Ajayi, Olabode O.; Snyper, Nana Yaa; Niang, Lamine; Diop, Halimatou; Ndoye, Medina; Mensah, James E.; Abrahams, Afua O. D.; Biritwum, Richard; Adjei, Andrew A.; Adebiyi, Akindele O.; Shittu, Olayiwola; Ogunbiyi, Olufemi; Adebayo, Sikiru; Nwegbu, Maxwell M.; Ajibola, Hafees O.; Oluwole, Olabode P.; Jamda, Mustapha A.; Pentz, Audrey; Haiman, Christopher A.; Spies, Petrus V.; van der Merwe, Andre; Cook, Michael B.; Chanock, Stephen J.; Berndt, Sonja I.; Watya, Stephen; Lubwama, Alexander; Muchengeti, Mazvita; Doherty, Sean; Smyth, Natalie; Lounsbury, David; Fortier, Brian; Rohan, Thomas E.; Jacobson, Judith S.; Neugut, Alfred I.; Hsing, Ann W.; Gusev, Alexander; Aisuodionoe-Shadrach, Oseremen I.; Joffe, Maureen; Adusei, Ben; Gueye, Serigne M.; Fernandez, Pedro W.; Mcbride, Jo; Andrews, Caroline; Petersen, Lindsay N.; Lachance, Joseph; Rebbeck, Timothy R.
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errSave
Limiting bias in AI models for improved and equitable cancer care
errNATURE REVIEWS CANCER
IF66.8
err2024-08-27
err0
PREAI
errGhassemi, Marzyeh; Gusev, Alexander
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errSave
Additional impact of genetic ancestry over race/ethnicity to prevalence of KRAS mutations and allele-specific subtypes in non-small cell lung cancer
errHUMAN GENETICS AND GENOMICS ADVANCES
IF3.6
err2024-07-01
err1
errOAAI
errWang, Xinan; Hou, Kangcheng; Ricciuti, Biagio; Alessi, Joao, V; Li, Xihao; Pecci, Federica; Dey, Rounak; Luo, Jia; Awad, Mark M.; Gusev, Alexander; Lin, Xihong; Johnson, Bruce E.; Christiani, David C.
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errSave
MSGene: a multistate model using genetic risk and the electronic health record applied to lifetime risk of coronary artery disease
errNATURE COMMUNICATIONS
IF15.7
err2024-06-07
err1
errOAAI
errUrbut, Sarah M.; Yeung, Ming Wai; Khurshid, Shaan; Cho, So Mi Jemma; Schuermans, Art; German, Jakob; Taraszka, Kodi; Paruchuri, Kaavya; Fahed, Akl C.; Ellinor, Patrick T.; Trinquart, Ludovic; Parmigiani, Giovanni; Gusev, Alexander; Natarajan, Pradeep
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errSave
Brain cell-type shifts in Alzheimer's disease, autism, and schizophrenia interrogated using methylomics and genetics
errSCIENCE ADVANCES
IF12.5
err2024-05-24
err2
errOAAI
errYap, Chloe X.; Vo, Daniel D.; Heffel, Matthew G.; Bhattacharya, Arjun; Wen, Cindy; Yang, Yuanhao; Kemper, Kathryn E.; Zeng, Jian; Zheng, Zhili; Zhu, Zhihong; Hannon, Eilis; Vellame, Dorothea Seiler; Franklin, Alice; Caggiano, Christa; Wamsley, Brie; Geschwind, Daniel H.; Zaitlen, Noah; Gusev, Alexander; Pasaniuc, Bogdan; Mill, Jonathan; Luo, Chongyuan; Gandal, Michael J.
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errSave
The Cox proportional hazards mixed model enables accurate estimation of the total effect somatic SNVs have on treatment outcomes
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errTaraszka, Kodi; Gusev, Alexander
errShare
errSave
Additional impact of genetic ancestry over self-reported race/ethnicity to prevalence of KRAS mutations and allele-specific subtypes in non-small cell lung cancer
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errWang, Xinan; Hou, Kangcheng; Ricciuti, Biagio; Alessi, Joao V.; Li, Xihao; Pecci, Federica; Dey, Rounak; Luo, Jia; Awad, Mark M.; Gusev, Alexander; Lin, Xihong; Johnson, Bruce E.; Christiani, David C.
errShare
errSave
Leveraging machine-learning approaches to dissect drivers of clinical metastatic dynamics in lung adenocarcinoma
errCANCER RESEARCH
IF16.6
err2024-03-22
err1
PREAI
errAprati, Tyler; Manos, Michael; Tarantino, Giuseppe; Glettig, Marc; Griffin, Maryclare; Gusev, Alexander; Kehl, Kenneth; Liu, David
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errSave
Cancer type and histology influence cutaneous immunotherapy toxicities: a multi-institutional cohort study
errBRITISH JOURNAL OF DERMATOLOGY
IF9.6
err2024-02-15
err2
errOAAI
errWan, Guihong; Khattab, Sara; Leung, Bonnie W.; Zhang, Shijia; Nguyen, Nga; Tran, Matthew; Lin, Chuck; Chang, Crystal; Alexander, Nora; Jairath, Ruple; Phillipps, Jordan; Tang, Kimberly; Rajeh, Ahmad; Zubiri, Leyre; Chen, Steven T.; Demehri, Shadmehr; Yu, Kun-Hsing; Gusev, Alexander; Kwatra, Shawn G.; Leboeuf, Nicole R.; Reynolds, Kerry L.; Semenov, Yevgeniy R.
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errSave
A comprehensive analysis of clinical and polygenic germline influences on somatic mutational burden
errAMERICAN JOURNAL OF HUMAN GENETICS
IF8.1
err2024-02-01
err2
errOAAI
errTaraszka, Kodi; Groha, Stefan; King, David; Tell, Robert; White, Kevin; Ziv, Elad; Zaitlen, Noah; Gusev, Alexander
errShare
errSave
Development and validation of time-to-event models to predict metastatic recurrence of localized cutaneous melanoma
errJOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
IF11.8
err2024-02-01
err2
errOAAI
errWan, Guihong; Leung, Bonnie W.; Desimone, Mia S.; Nguyen, Nga; Rajeh, Ahmad; Collier, Michael R.; Rashdan, Hannah; Roster, Katie; Zhou, Xu; Moseley, Cameron B.; Nirmal, Ajit J.; Pelletier, Roxanne J.; Maliga, Zoltan; Marko, Gyorgy; Nemeth, Istvan Balazs; Tsao, Hensin; Asgari, Maryam M.; Gusev, Alexander; Stagner, Anna M.; Lian, Christine G.; Hurlbert, Marc S.; Liu, Feng; Yu, Kun-Hsing; Sorger, Peter K.; Semenov, Yevgeniy R.
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Research Directions

No research directions
Co-authors
Cooperation Journals
J
JoAnn E. Manson
H-index: 255 · Papers: 2.7K
M
Mark J. Daly
H-index: 224 · Papers: 1.2K
B
Brenda W.J.H. Penninx
H-index: 210 · Papers: 1.8K
H
Hermann Brenner
H-index: 202 · Papers: 3.3K
B
Børge G. Nordestgaard
H-index: 192 · Papers: 1.8K
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