Not logged in AKT/mTOR signaling modulates resistance to endocrine therapy and CDK4/6 inhibition in metastatic breast cancers Abu-Khalaf, Maysa M.; Alex Hodge, K.; Hatzis, Christos; Baldelli, Elisa; El Gazzah, Emna; Valdes, Frances; Sikov, William M.; Mita, Monica M.; Denduluri, Neelima; Murphy, Rita; Zelterman, Daniel; Liotta, Lance; Dunetz, Bryant; Dunetz, Rick; Petricoin, Emanuel F.; Pierobon, Mariaelena Share Save
Activation of the AKT/mTOR signaling pathway is associated with response to the combination of endocrine therapy and CDK4/6 inhibitor in HR+/HER2-metastatic breast cancer Abu-Khalaf, Maysa; Hatzis, Christos; Hodge, K. Alex; Baldelli, Elisa; Sikov, William; Mita, Monica; Valdes-Albini, Frances; Dunetz, Bryant; Petricoin, Emanuel; Pierobon, Mariaelena Share Save
Intra- and Interlaboratory Reproducibility of the Sensitivity to Endocrine Therapy Assay for Stage II/III Breast Cancer Bossuyt, Veerle; Lau, Rosanna; Young, Brandon; Howe, John Greg; Zhao, Fengmin; Leyland-Jones, Brian; Du, Lili; Foli, Tiffany; Hatzis, Christos; Symmans, W. Fraser Share Save
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Targeted RNAseq assay incorporating unique molecular identifiers for improved quantification of gene expression signatures and transcribed mutation fraction in fixed tumor samples Fu, Chunxiao; Marczyk, Michal; Samuels, Michael; Trevarton, Alexander J.; Qu, Jiaxin; Lau, Rosanna; Du, Lili; Pappas, Todd; Sinn, Bruno, V; Gould, Rebekah E.; Pusztai, Lajos; Hatzis, Christos; Symmans, W. Fraser Share Save
IMMUNE CELL PROFILING ACROSS SOLID TUMOR TYPES BY MASS CYTOMETRY REVEALS TUMOR ENRICHMENT OF PD-1+/LAG-3+CD8 MEMORY T CELLS THAT EXHIBIT TUMOR-REACTIVE YET DYSFUNCTIONAL FEATURES Garman, Bradley; Menard, Laurence; Jiang, Can; Daouti, Sherif; Mehta, Priyanka; Jacques, Miye; Bolisetty, Mohan; Hatzis, Christos; Orduno, Nataly Manjarrez; Bowden, Michaela; David, Justin; David, Justin; David, Justin Share Save
INTEGRATIVE MOLECULAR PROFILING OF HIGH-GRADE PRIMARY PROSTATE CANCER IDENTIFIES PATIENTS WITH A BIOMARKER PROFILE THAT FAVORS THE COMBINATION OF STANDARD OF CARE (SOC) THERAPY WITH IMMUNOTHERAPY Gjini, Evisa; Trillo-Tinoco, Jimena; Browne, Andrew; Powles, Ryan; Wang, Tai; Tauras, Christine; Lako, Ana; Ferrer-Luna, Ruben; Bleicher, Zoe; Consedine, Timothy; Zhou, Chensheng; Kelemen, Evan; Lewin, Anne; King, Catherine; Bhattacharya, Sumit; Bell-Temin, Harris; Dongre, Ashok; Nelson, David; Hatzis, Christos; Macisaac, Kenzie; Towfic, Fadi; Chen, Benjamin; Bowden, Michaela Share Save
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Genomic, transcriptomic, and epigenetic profiling of triple-negative breast cancer cells after Navitoclax treatment Marczyk, Michal; Gunasekharan, Vignesh; Zhao, Jun; Qu, Rihao; Li, Xiaotong; Patwardhan, Gauri A.; Wali, Vikram B.; Gupta, Abhishek K.; Pillai, Manoj M.; Kluger, Yuval; Hatzis, Christos; Pusztai, Lajos Share Save
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Germline variant burden in cancer genes correlates with age at diagnosis and somatic mutation burden Qing, Tao; Mohsen, Hussein; Marczyk, Michal; Ye, Yixuan; O'Meara, Tess; Zhao, Hongyu; Townsend, Jeffrey P.; Gerstein, Mark; Hatzis, Christos; Kluger, Yuval; Pusztai, Lajos Share Save
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Site of recurrence after neoadjuvant therapy: Clues to biology and impact on endpoints Yau, Christina; DeMichele, Angela; Symmans, W. Fraser; Pusztai, Lajos; Yee, Douglas; Clark, Amy S.; Hatzis, Christos; Matthews, Jeffrey B.; Carter, Jodi; Chen, Yunn-Yi; Cole, Kimberly; Khazai, Laila; Klein, Molly; Kokh, Dina; Krings, Gregor; Sahoo, Sunati; Albain, Kathy S.; Chien, A. Jo; Edmiston, Kirsten K.; Elias, Anthony D.; Ellis, Erin D.; Euhus, David M.; Han, Heather S.; Isaacs, Claudine; Khan, Qamar J.; Lang, Julie E.; Lu, Janice; Meisel, Jane L.; Mitri, Zaha; Nanda, Rita; Northfelt, Donald W.; Sanft, Tara; Stringer-Reasor, Erica; Viscusi, Rebecca K.; Wallace, Anne M.; Yung, Rachel; Hylton, Nola M.; Boughey, Judy C.; Melisko, Michelle E.; Perlmutter, Jane; Rugo, Hope S.; Schwab, Richard; van't Veer, Laura J.; Berry, Donald A.; Esserman, Laura J. Share Save
Neoadjuvant aromatase inhibitor therapy plus the mTOR inhibitor everolimus in postmenopausal women with hormone receptor positive/HER2 negative breast cancer and an oncotype Dx recurrence score (≤25) Abu-Khalaf, Maysa M.; Aderhold, Kimberly; Marczyk, Michal; Chung, Gina; Hofstatter, Erin; Sanft, Tara; Silber, Andrea; DiGiovanna, Michael; Zelterman, Daniel; Puzstai, Lajos; Hatzis, Christos Share Save
The impact of RNA extraction method on accurate RNA sequencing from formalin-fixed paraffin-embedded tissues Marczyk, Michal; Fu, Chunxiao; Lau, Rosanna; Du, Lili; Trevarton, Alexander J.; Sinn, Bruno V.; Gould, Rebekah E.; Pusztai, Lajos; Hatzis, Christos; Symmans, W. Fraser Share Save
Identification and Validation of a Novel Biologics Target in Triple Negative Breast Cancer Wali, Vikram B.; Patwardhan, Gauri A.; Pelekanou, Vasiliki; Karn, Thomas; Cao, Jian; Ocana, Alberto; Yan, Qin; Nelson, Bryce; Hatzis, Christos; Pusztai, Lajos Share Save
Pathway level alterations rather than mutations in single genes predict response to HER2-targeted therapies in the neo-ALTTO trial (vol 28, pg 128, 2017) Shi, W.; Jiang, T.; Nuciforo, P.; Hatzis, C.; Holmes, E.; Harbeck, N.; Sotiriou, C.; Pena, L.; Loi, S.; Rosa, D. D.; Chia, S.; Wardley, A.; Ueno, T.; Rossari, J.; Eidtmann, H.; Armour, A.; Piccart-Gebhart, M.; Rimm, D. L.; Baselga, J.; Pusztai, L. Share Save
SETER/PR: a robust 18-gene predictor for sensitivity to endocrine therapy for metastatic breast cancer Sinn, Bruno, V; Fu, Chunxiao; Lau, Rosanna; Litton, Jennifer; Tsai, Tsung-Heng; Murthy, Rashmi; Tam, Alda; Andreopoulou, Eleni; Gong, Yun; Murthy, Ravi; Gould, Rebekah; Zhang, Ya; King, Tani A.; Viale, Agnes; Andrade, Victor; Giri, Dilip; Salgado, Roberto; Laios, Ioanna; Sotiriou, Christos; Marginean, Esmeralda C.; Kwiatkowski, Danielle N.; Layman, Rachel M.; Booser, Daniel; Hatzis, Christos; Valero, V. Vicente; Symmans, W. Fraser Share Save
The impact of communication style on patient satisfaction Trant, Amelia A.; Szekely, Borbala; Mougalian, Sarah S.; DiGiovanna, Michael P.; Sanft, Tara; Hofstatter, Erin; Silber, Andrea; Adelson, Kerin B.; Chagpar, Anees; Killelea, Brigid; Horowitz, Nina; Lannin, Donald; Park, Tristen; Corso, Michelle; Abraham, Gineesha; Pollard-Murphy, Karen; Sturrock, Tracy; Knill-Selby, Elspeth; Western, Ashley; Servodidio, Camille; Tasoulis, Marios Konstantinos; Healy, Barbara; Hatzis, Christos; Pusztai, Lajos Share Save
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