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Patrick Y. Wen

mass general brigham cancer institute and harvard medical school

145H-index
1.9KPaper Count
8.7WCitation Count
Published Papers 528
Publication Date
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Exploring the landscape of targetable alterations in patients with glioblastoma
errNature Reviews Clinical Oncology
IF82.2
err2026-08-19
err0
PREAI
errElisa Aquilanti; Mehdi Touat; Pim French; Antonio Iavarone; David Capper; Marjolein Geurts; Rifaquat Rahman; Roel Verhaak; Matthias Preusser; Martin van den Bent; Patrick Y. Wen
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errSave
Anti-LAG-3 with or without anti-PD-1 in recurrent glioblastoma: a phase 1 trial
errNature Medicine
IF50
err2026-07-10
err0
errOAAI
errMichael Lim; Xiaobu Ye; Anna F. Piotrowski; Arati Desai; Manmeet S. Ahluwalia; Tobias Walbert; Glenn Lesser; Benjamin M. Ellingson; David M. Peereboom; Joy D. Fisher; Serena Desideri; Christina Jackson; Ayush Pant; Aanchal Jain; Rohit Verma; Benjamin Oberlton; Hadeesha Piyadasa; Chetan Bettegowda; Logan Engle; Janis Taube; Sean C. Bendall; John Choi; Jan Drappatz; Frank S. Lieberman; Lawrence R. Kleinberg; Drew M. Pardoll; Louis B. Nabors; Patrick Y. Wen; Stuart A. Grossman
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errSave
Publisher Correction: Tumor transcriptional state predicts survival in immune-checkpoint-blockade-treated glioblastoma
errNature Cancer
IF28.5
err2026-06-12
err0
PREAI
errJack Y. Ghannam; Julian Bryan; Jakob Weiss; Daniel Kovarsky; David Merrell; Conor Messer; Kristy Schlueter-Kuck; Geoffrey G. Fell; Mary Jane Lim-Fat; Gilbert Youssef; Rifaquat Rahman; Lei Qin; Geoffrey S. Young; J. Thomas Janes; McKayla Van Orden; Kathleen L. Pfaff; Andrew Gans; Emma S. Lin; Raymond Y. Huang; Brian P. Danysh; Laxmi Parida; Shuqiang Li; Patrick Y. Wen; E. Antonio Chiocca; Donna Neuberg; Keith L. Ligon; Itay Tirosh; David A. Reardon; Gad Getz; Catherine J. Wu
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errSave
Tumor transcriptional state predicts survival in immune-checkpoint-blockade-treated glioblastoma
errNature Cancer
IF28.5
err2026-06-03
err0
PREAI
errJack Y. Ghannam; Julian Bryan; Jakob Weiss; Daniel Kovarsky; David Merrell; Conor Messer; Kristy Schlueter-Kuck; Geoffrey G. Fell; Mary Jane Lim-Fat; Gilbert Youssef; Rifaquat Rahman; Lei Qin; Geoffrey S. Young; J. Thomas Janes; McKayla Van Orden; Kathleen L. Pfaff; Andrew Gans; Emma S. Lin; Raymond Y. Huang; Brian P. Danysh; Laxmi Parida; Shuqiang Li; Patrick Y. Wen; E. Antonio Chiocca; Donna Neuberg; Keith L. Ligon; Itay Tirosh; David A. Reardon; Gad Getz; Catherine J. Wu
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errSave
Prognostic significance of O6-methylguanine-DNA methyltransferase promoter methylation status in isocitrate dehydrogenase-mutant glioma
errNeuro-Oncology
IF13.4
err2025-12-15
err0
PREAI
errGilbert Youssef; Elisa Aquilanti; Julie J Miller; Zhou Lan; Aleksandra B Lasica; Isabel Arrillaga-Romany; Tracy T Batchelor; Tamar R Berger; Rameen Beroukhim; Ugonma Chukwueke; Jorg Dietrich; Deborah A Forst; Elizabeth R Gerstner; L Nicolas Gonzalez Castro; Justin T Jordan; J Ricardo Mcfaline-Figueroa; Eudocia Quant Lee; Lakshmi Nayak; Vihang Nakhate; Juan Pablo Ospina; Scott R Plotkin; Nancy Wang; John Y Rhee; David A Reardon; Patrick Y Wen
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errSave
CTIM-12. DUAL IMMUNE CHECKPOINT BLOCKADE FOR SURGICALLY ACCESSIBLE RECURRENT GLIOBLASTOMA: CLINICAL AND MOLECULAR OUTCOMES
errNeuro-Oncology
IF13.4
err2025-11-11
err0
errOAAI
errLu Sun; Eudocia Quant Lee; Gang Li; David A Reardon; Brenda Acevedo; Catharina Westergaard; Alyssa Russ; Richard G Everson; Benjamin M Ellingson; Ingo K Mellinghoff; Elisa Aquilanti; L Nicolas Gonzalez Castro; J Ricardo McFaline-Figueroa; Lakshmi Nayak; Rameen Beroukhim; Robert A Chong; Jacqueline Stone; Thomas Kaley; Lauren Schaff; Jessica wilcox; Maria Lavallee; Ugonma Chukwueke; Annick D Van den Abbeele; Michael Lim; Timothy F Cloughesy; Robert M Prins; Patrick Y Wen
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errSave
CTNI-53. PATIENTS WITH ISOCITRATE DEHYDROGENASE-MUTANT GLIOMA TREATED WITH VORASIDENIB: UPDATED DATA FROM THE VORASIDENIB EXPANDED ACCESS PROGRAM
errNeuro-Oncology
IF13.4
err2025-11-11
err0
errOAAI
errTimothy F Cloughesy; Katherine B Peters; Howard Colman; Jennie W Taylor; Ingo K Mellinghoff; Helen A Shih; Christelle Chacar; Jonathan Dewey; Patrick Y Wen
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errSave
NCOG-43. Clinical outcomes in patients with molecular vs histological glioblastoma
errNeuro-Oncology
IF13.4
err2025-11-11
err0
errOAAI
errJuan Pablo Ospina; Prem Sai Prabhakar; Catharina Westergaard; Alyssa Russ; Rachel Fox; Ernest Wang; Julia Japo; Julien Rousseau; Vihang Nakhate; Tamar R Berger; John Y Rhee; Elisa Aquilanti; Ugonma N Chukwueke; L Nicolas Gonzalez Castro; Eudocia Q Lee; Lakshmi Nayak; David A Reardon; Raymond Y Huang; Keith L Ligon; Patrick Y Wen; Gilbert Youssef
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errSave
SAFETY AND TOLERABILITY OF OLAPARIB, TEMOZOLOMIDE, AND PEMBROLIZUMAB IN A PHASE 2 TRIAL IN PATIENTS WITH PROGRESSIVE GLIOBLASTOMA
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errCastro, L. Nicolas Gonzalez; McCluskey, Christine; Westergaard, Catharina; Fox, Rachel; Chukwueke, Ugonma; Youssef, Gilbert; Aquilanti, Elisa; Lee, Eudocia; Reardon, David; Arnaout, Omar; Bi, Wenya L.; Peruzzi, Pierpaolo; Golby, Alexandra; Kim, Jiyoon; Vega, Rafael; Schaff, Lauren; Arrillaga-Romany, Isabel; Ligon, Keith; Prins, Robert; Wen, Patrick
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errSave
UPDATED RESULTS OF PHASE 3 STELLAR TRIAL: EFLORNITHINE IMPROVES OVERALL SURVIVAL AND BLINDED INDEPENDENT CENTRAL REVIEW DETERMINED PROGRESSION FREE SURVIVAL IN PATIENTS WITH RECURRENT WHO 2021 GRADE 3 IDH-MUTANT ASTROCYTOMA
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errColman, Howard; Lombardi, Giuseppe; Wong, Eric; Walbert, Tobias; Eoli, Marica; Lassman, Andrew; Peereboom, David; Kizilbash, Sani; Kamiya-Matsuoka, Carlos; Pitz, Marshall; Strowd, Roy; Desjardins, Annick; Kumthekar, Priya; Mason, Warren; Pellerino, Alessia; Soffietti, Riccardo; Butowski, Nicholas; Forsyth, Peter; Hamza, Mohamed; Hau, Peter; Lallana, Enrico; Nabors, Burt; Piccioni, David; Uhlmann, Erik; Welsh, Liam; Wen, Patrick; Dietrich, Jorg; Levin, Victor
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errSave
Multivariate survival risk stratification in GBMs lacking necrosis and microvascular proliferation
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errMolinaro, Annette; McCoy, Lucie; Warrier, Gayathri; Al-Adli, Nadeem; Young, Jacob S.; Mendez, Joe; Malani, Rachna; Hamel, Elaine; Odell, Jennifer Ledbetter; Eldred, Blaine; Nghiemphu, Phioanh; Liau, Linda M.; Ligon, Keith; Reardon, David A.; Lachance, Daniel; Decker, Paul; Eckel-Passow, Jeanette; Burns, Terry; Kosel, Matthew; Ida, Cristiane; Vaubel, Rachael; Giannini, Caterina; Kollmeyer, Thomas; Kizilbash, Sani; Maqbool, Muhammad Asad; Shafqat, Shameel; Mansouri, Alireza; Jenkins, Robert; Cloughesy, Timothy; Lai, Albert; Youssef, Gilbert; Wen, Patrick; Solomon, David; Chang, Susan; de Groot, John; Colman, Howard
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errSave
Volumetric (3D) compared with traditional bidirectional (2D) assessment in patients with Grade 2, isocitrate dehydrogenase 1/2 mutant (mIDH1/2) glioma receiving vorasidenib or placebo in the Phase 3 INDIGO trial
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errEllingson, Benjamin M.; Mellinghoff, Ingo; Van Den Bent, Martin J.; Blumenthal, Deborah T.; Touat, Mehdi; Peters, Katherine B.; Clarke, Jennifer L.; Mendez, Joe; Yust-Katz, Shlomit; Welsh, Liam; Mason, Warren P.; Ducray, Francois; Umemura, Yoshie; Nabors, Burt; Holdhoff, Matthias; Hottinger, Andreas F.; Arakawa, Yoshiki; Sepulveda, Juan M.; Wick, Wolfgang; Soffietti, Riccardo; Perry, James; Giglio, Pierre; De La Fuente, Macarena, I; Maher, Elizabeth; Zhao, Dan; Pandya, Shuchi S.; Steelman, Lori; Hassan, Islam; Wen, Patrick Y.; Cloughesy, Timothy F.
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errSave
DEFICITS IN GAIT QUANTIFIED BY LARGE LANGUAGE MODEL-DERIVED NANO SCORES PREDICT SURVIVAL IN HIGH-GRADE GLIOMA
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errRhee, John; Tentor, Zachary; Beroukhim, Rameen; Lee, Eudocia; Aquilanti, Elisa; Berger, Tamar; Batchelor, Tracy; Castro, Luis Nicolas Gonzalez; Youssef, Gilbert; Chukwueke, Ugonma; Wen, Patrick; Reardon, David; Lim-Fat, Mary Jane; Lindvall, Charlotta; Nayak, Lakshmi
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errSave
Outcomes from online education focused on novel targeted therapies for IDH-mutant gliomas
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errFiske, Zhizhi; Grainger, Deborah; Adair, Gill; Habib, Jamie; Ellingson, Benjamin; Piil, Karin; Van Den Bent, Martin; Lim, Michael; Wen, Patrick
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errSave
PHASE 1B SAFETY RESULTS OF VORASIDENIB IN COMBINATION WITH TEMOZOLOMIDE IN PATIENTS WITH MUTANT IDH1 OR IDH2 GLIOMA
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errde la Fuente, Macarena, I; Cloughesy, Timothy F.; Touat, Mehdi; Lopez, Juanita; McBain, Catherine; Steelman, Lori; Hassan, Islam; Jain, Payal; Man, Albert; Abshire, Michelle; Knipstein, Jeffrey; Mellinghoff, Ingo; Wen, Patrick Y.
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errSave
Preclinical and clinical assessment of chemoradiation after mutant IDH inhibitor treatment in IDH-mutant glioma
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errShi, Diana; Calvo-Fernandez, Ester; Puliyappadamba, Vinesh; Lanman, Tyler; Cruickshank, Aiden; Prost, Diego; Xiao, Yi; Neumann, Ethan; Gudipelly, Sriram; Clark, Louise; Kaphle, Pranita; Shipman, Tracey; Levitt, Michael; Lin, Mathew; Tsai, Alexander; Lee, Joyce; Simons, Donald; Tyagi, Ethika; Rahman, Rifaquat; De Nguyen, Quang-; Wen, Patrick; Haas-Kogan, Daphne; Yates, Kathleen; Manguso, Robert; Bardeesy, Nabeel; Bernstein, Bradley; Wu, Jingyi; Abdullah, Kalil; Jain, Payal; Tron, Adriana; Touat, Mehdi; Castro, L. Nicolas Gonzalez; Suva, Mario; Kaelin, William; Mcbrayer, Samuel
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errSave
Effectiveness of an online CME curriculum on physicians' understanding of novel treatment approaches to IDH-mutant gliomas
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errFiske, Zhizhi; Grainger, Deborah; Adair, Gill; Habib, Jamie; van den Bent, Martin; de la Fuente, Macarena; Lim, Michael; Preusser, Matthias; Wen, Patrick
errShare
errSave
Polycomb repressor complex 2, its catalytic subunit EZH2 and its functional partner DNA methyltransferase 1 suppress tumoral MHC class 1 and modulate the tumor immune microenvironment in glioblastoma
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errD'auteuil, Andrew; Nakhawa, Shreya; Ni, Jing; Ligon, Keith L.; Wen, Patrick; Reardon, David; Huang, Kun; Zhao, Jean; Mcfaline-Figueroa, J. Ricardo
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errSave
IMPACT OF SMALLER CLINICAL TARGET VOLUME EXPANSIONS FOR THE RADIATION TREATMENT OF NEWLY DIAGNOSED GLIOBLASTOMA
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errTan, Yujue; Hill, Jordan; Tjong, Michael; Youssef, Gilbert; Aizer, Ayal; Tanguturi, Shyam; Shi, Diana; Lamba, Nayan; Leeman, Jonathan; Wen, Patrick; Rahman, Rifaquat
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errSave
BASELINE NEUROLOGICAL FUNCTION ASSESSED BY NANO PREDICTS PROGRESSION-FREE SURVIVAL IN GLIOBLASTOMA
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errRaheem, Javeria; Chan, Aimee; Allen, Marie; Fox, Rachel; Theriault, Aimee; Granovskaya, Inga; Wong, Andrea; Calabrese, Eirena; Roberto, Katrina; Godoy-Santin, Jaime; Rhee, John; Wen, Patrick Y.; Reardon, David; Perry, James; Nayak, Lakshmi; Lim-Fat, Mary Jane
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errSave

Research Directions

No research directions
Co-authors
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