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Applicability of mitotic figure counting by deep learning: a development and pan-cancer validation study Kalsnes, Joakim; Isaksen, Maria X.; Julbo, Frida; Pradhan, Manohar; Kleppe, Andreas; De Raedt, Sepp; Skrede, Ole-Johan; Torheim, Turid; Nesheim, John Arne; Mohn, Hans Martin; Askautrud, Hanne A.; Cyll, Karolina; Kildal, Wanja; Rewcastle, Emma; Lillesand, Melinda; Kvikstad, Vebjorn; Janssen, Emiel; Jones, Robert; Brustugun, Odd Terje; Brennhovd, Bjorn; Haug, Erik Skaaheim; Busund, Lill-Tove Rasmussen; Richardsen, Elin; Andersen, Sigve; Donnem, Tom; Lindemann, Kristina; Kristensen, Gunnar; Shepherd, Neil A.; Novelli, Marco; Liestol, Knut; Kerr, David; Danielsen, Havard E.; Hveem, Tarjei S. Share Save
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Bestrophin-4 relays HES4 and interacts with TWIST1 to suppress epithelial-to-mesenchymal transition in colorectal cancer cells Wang, Zijing; Xia, Bihan; Qi, Shaochong; Zhang, Xian; Zhang, Xiaoshuang; Li, Yan; Wang, Huimin; Zhang, Miao; Zhao, Ziyi; Kerr, David; Yang, Li; Cai, Shijie; Yang, Jilin Share Save
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Single-cell AI-based detection and prognostic and predictive value of DNA mismatch repair deficiency in colorectal cancer Nowak, Marta; Jabbar, Faiz; Rodewald, Ann-Katrin; Gneo, Luciana; Tomasevic, Tijana; Harkin, Andrea; Iveson, Tim; Saunders, Mark; Kerr, Rachel; Oein, Karin; Maka, Noori; Hay, Jennifer; Edwards, Joanne; Tomlinson, Ian; Sansom, Owen; Kelly, Caroline; Pezzella, Francesco; Kerr, David; Easton, Alistair; Domingo, Enric; Koelzer, Viktor H.; Church, David N. Share Save
Unification of Efforts to Improve Global Access to Cancer Therapeutics: Report From the 2022/2023 Access to Essential Cancer Medicines Stakeholder Summit Briercheck, Edward; Pyle, Doug; Adams, Cary; Atun, Rifat; Booth, Christopher; Dent, Jennifer; Garcia-Gonzalez, Pat; Ilbawi, Andre; Jazieh, Abdul Rahman; Kerr, David; Knaul, Felicia; Kobayashi, Emily; Lim, Christopher; Maza, Maurizio; Milner, Danny; Navarro, Maria Fernanda; O'Brien, Meg; Rodriguez-Galindo, Carlos; Sullivan, Richard; Torode, Julie; Vokes, Everett; Gralow, Julie Share Save
Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes Chen, Zhishan; Guo, Xingyi; Tao, Ran; Huyghe, Jeroen R.; Law, Philip J.; Fernandez-Rozadilla, Ceres; Ping, Jie; Jia, Guochong; Long, Jirong; Li, Chao; Shen, Quanhu; Xie, Yuhan; Timofeeva, Maria N.; Thomas, Minta; Schmit, Stephanie L.; Diez-Obrero, Virginia; Devall, Matthew; Moratalla-Navarro, Ferran; Fernandez-Tajes, Juan; Palles, Claire; Sherwood, Kitty; Briggs, Sarah E. W.; Svinti, Victoria; Donnelly, Kevin; Farrington, Susan M.; Blackmur, James; Vaughan-Shaw, Peter G.; Shu, Xiao-Ou; Lu, Yingchang; Broderick, Peter; Studd, James; Harrison, Tabitha A.; Conti, David V.; Schumacher, Fredrick R.; Melas, Marilena; Rennert, Gad; Obon-Santacana, Mireia; Martin-Sanchez, Vicente; Oh, Jae Hwan; Kim, Jeongseon; Jee, Sun Ha; Jung, Keum Ji; Kweon, Sun-Seog; Shin, Min-Ho; Shin, Aesun; Ahn, Yoon-Ok; Kim, Dong-Hyun; Oze, Isao; Wen, Wanqing; Matsuo, Keitaro; Matsuda, Koichi; Tanikawa, Chizu; Ren, Zefang; Gao, Yu-Tang; Jia, Wei-Hua; Hopper, John L.; Jenkins, Mark A.; Win, Aung Ko; Pai, Rish K.; Figueiredo, Jane C.; Haile, Robert W.; Gallinger, Steven; Woods, Michael O.; Newcomb, Polly A.; Duggan, David; Cheadle, Jeremy P.; Kaplan, Richard; Kerr, Rachel; Kerr, David; Kirac, Iva; Bohm, Jan; Mecklin, Jukka-Pekka; Jousilahti, Pekka; Knekt, Paul; Aaltonen, Lauri A.; Rissanen, Harri; Pukkala, Eero; Eriksson, Johan G.; Cajuso, Tatiana; Hanninen, Ulrika; Kondelin, Johanna; Palin, Kimmo; Tanskanen, Tomas; Renkonen-Sinisalo, Laura; Mannisto, Satu; Albanes, Demetrius; Weinstein, Stephanie J.; Ruiz-Narvaez, Edward; Palmer, Julie R.; Buchanan, Daniel D.; Platz, Elizabeth A.; Visvanathan, Kala; Ulrich, Cornelia M.; Siegel, Erin; Brezina, Stefanie; Gsur, Andrea; Campbell, Peter T.; Chang-Claude, Jenny; Hoffmeister, Michael; Brenner, Hermann; Slattery, Martha L.; Potter, John D.; Tsilidis, Kostas K.; Schulze, Matthias B.; Gunter, Marc J.; Murphy, Neil; Castells, Antoni; Castellvi-Bel, Sergi; Moreira, Leticia; Arndt, Volker; Shcherbina, Anna; Bishop, D. Timothy; Giles, Graham G.; Southey, Melissa C.; Idos, Gregory E.; McDonnell, Kevin J.; Abu-Ful, Zomoroda; Greenson, Joel K.; Shulman, Katerina; Lejbkowicz, Flavio; Offit, Kenneth; Su, Yu-Ru; Steinfelder, Robert; Keku, Temitope O.; van Guelpen, Bethany; Hudson, Thomas J.; Hampel, Heather; Pearlman, Rachel; Berndt, Sonja I.; Hayes, Richard B.; Martinez, Marie Elena; Thomas, Sushma S.; Pharoah, Paul D. P.; Larsson, Susanna C.; Yen, Yun; Lenz, Heinz-Josef; White, Emily; Li, Li; Doheny, Kimberly F.; Pugh, Elizabeth; Shelford, Tameka; Chan, Andrew T.; Cruz-Correa, Marcia; Lindblom, Annika; Hunter, David J.; Joshi, Amit D.; Schafmayer, Clemens; Scacheri, Peter C.; Kundaje, Anshul; Schoen, Robert E.; Hampe, Jochen; Stadler, Zsofia K.; Vodicka, Pavel; Vodickova, Ludmila; Vymetalkova, Veronika; Edlund, Christopher K.; Gauderman, W. James; Shibata, David; Toland, Amanda; Markowitz, Sanford; Kim, Andre; Chanock, Stephen J.; van Duijnhoven, Franzel; Feskens, Edith J. M.; Sakoda, Lori C.; Gago-Dominguez, Manuela; Wolk, Alicja; Pardini, Barbara; FitzGerald, Liesel M.; Lee, Soo Chin; Ogino, Shuji; Bien, Stephanie A.; Kooperberg, Charles; Li, Christopher I.; Lin, Yi; Prentice, Ross; Qu, Conghui; Bezieau, Stephane; Yamaji, Taiki; Sawada, Norie; Iwasaki, Motoki; Le Marchand, Loic; Wu, Anna H.; Qu, Chenxu; McNeil, Caroline E.; Coetzee, Gerhard; Hayward, Caroline; Deary, Ian J.; Harris, Sarah E.; Theodoratou, Evropi; Reid, Stuart; Walker, Marion; Ooi, Li Yin; Lau, Ken S.; Zhao, Hongyu; Hsu, Li; Cai, Qiuyin; Dunlop, Malcolm G.; Gruber, Stephen B.; Houlston, Richard S.; Moreno, Victor; Casey, Graham; Peters, Ulrike; Tomlinson, Ian; Zheng, Wei Share Save
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Dihydropyrimidine dehydrogenase gene variants for predicting grade 4-5 fluoropyrimidine-induced toxicity: FUSAFE individual patient data meta-analysis Le Teuff, Gwenael; Cozic, Nathalie; Boyer, Jean-Christophe; Boige, Valerie; Diasio, Robert B.; Taieb, Julien; Meulendijks, Didier; Palles, Claire; Schwab, Matthias; Deenen, Maarten; Largiader, Carlo R.; Marinaki, Anthony; Jennings, Barbara A.; Wettergren, Yvonne; Di Paolo, Antonello; Gross, Eva; Budai, Barna; Ackland, Stephen P.; van Kuilenburg, Andre B. P.; Mcleod, Howard L.; Milano, Gerard; Thomas, Fabienne; Loriot, Marie-Anne; Kerr, David; Schellens, Jan H. M.; Laurent-Puig, Pierre; Shi, Qian; Pignon, Jean-Pierre; Etienne-Grimaldi, Marie-Christine Share Save
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Multiparameter immunoprofiling reveals independent prognostic value of intraepithelial CD8 and intrastromal FoxP3 infiltrate in stage II/III colorectal cancer: Analysis of 3,409 cases from the SCOT and QUASAR2 trials Church, D. N.; Frei, A.; McGuigan, A.; Sinha, R.; Harkin, A.; Iveson, T. J.; Saunders, M. P.; Hay, J.; Edwards, J.; Sansom, O. J.; Kelly, C.; Kerr, R.; Kerr, D. J.; Domingo, E.; Koelzer, V. H. Share Save
Accounting for intensity variation in image analysis of large-scale multiplexed clinical trial datasets Frei, Anja L.; McGuigan, Anthony; Sinha, Ritik R. A. K.; Glaire, Mark A.; Jabbar, Faiz; Gneo, Luciana; Tomasevic, Tijana; Harkin, Andrea; Iveson, Tim J.; Saunders, Mark; Oein, Karin; Maka, Noori; Pezella, Francesco; Campo, Leticia; Hay, Jennifer; Edwards, Joanne; Sansom, Owen J.; Kelly, Caroline; Tomlinson, Ian; Kildal, Wanja; Kerr, Rachel S.; Kerr, David J.; Danielsen, Havard E.; Domingo, Enric; TransSCOT Consortium, David N.; Church, David N.; Koelzer, Viktor H. Share Save
GTP Cyclohydrolase Drives Breast Cancer Development and Promotes EMT in an Enzyme-Independent Manner Wang, Zijing; Zhang, Nan; Zhang, Miao; Jiang, Yao; Ng, Aik Seng; Bridges, Esther; Zhang, Wei; Zeng, Xin; Luo, Qi; Liang, Jiabien; Gyorffy, Balazs; Hublitz, Philip; Liang, Zhu; Fischer, Roman; Kerr, David; Harris, Adrian L.; Cai, Shijie Share Save
Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries (vol 55, pg 89, 2023) Fernandez-Rozadilla, Ceres; Timofeeva, Maria; Chen, Zhishan; Law, Philip; Thomas, Minta; Schmit, Stephanie; Diez-Obrero, Virginia; Hsu, Li; Fernandez-Tajes, Juan; Palles, Claire; Sherwood, Kitty; Briggs, Sarah; Svinti, Victoria; Donnelly, Kevin; Farrington, Susan; Blackmur, James; Vaughan-Shaw, Peter; Shu, Xiao-ou; Long, Jirong; Cai, Qiuyin; Guo, Xingyi; Lu, Yingchang; Broderick, Peter; Studd, James; Huyghe, Jeroen; Harrison, Tabitha; Conti, David; Dampier, Christopher; Devall, Mathew; Schumacher, Fredrick; Melas, Marilena; Rennert, Gad; Obon-Santacana, Mireia; Martin-Sanchez, Vicente; Moratalla-Navarro, Ferran; Oh, Jae Hwan; Kim, Jeongseon; Jee, Sun Ha; Jung, Keum Ji; Kweon, Sun-Seog; Shin, Min-Ho; Shin, Aesun; Ahn, Yoon-Ok; Kim, Dong-Hyun; Oze, Isao; Wen, Wanqing; Matsuo, Keitaro; Matsuda, Koichi; Tanikawa, Chizu; Ren, Zefang; Gao, Yu-Tang; Jia, Wei-Hua; Hopper, John; Jenkins, Mark; Win, Aung Ko; Pai, Rish; Figueiredo, Jane; Haile, Robert; Gallinger, Steven; Woods, Michael; Newcomb, Polly; Duggan, David; Cheadle, Jeremy; Kaplan, Richard; Maughan, Timothy; Kerr, Rachel; Kerr, David; Kirac, Iva; Bohm, Jan; Mecklin, Lukka-Pekka; Jousilahti, Pekka; Knekt, Paul; Aaltonen, Lauri; Rissanen, Harri; Pukkala, Eero; Eriksson, Johan; Cajuso, Tatiana; Hanninen, Ulrika; Kondelin, Johanna; Palin, Kimmo; Tanskanen, Tomas; Renkonen-Sinisalo, Laura; Zanke, Brent; Mannisto, Satu; Albanes, Demetrius; Weinstein, Stephanie; Ruiz-Narvaez, Edward; Palmer, Julie; Buchanan, Daniel; Platz, Elizabeth; Visvanathan, Kala; Ulrich, Cornelia; Siegel, Erin; Brezina, Stefanie; Gsur, Andrea; Campbell, Peter; Chang-Claude, Jenny; Hoffmeister, Michael; Brenner, Hermann; Slattery, Martha; Potter, John; Tsilidis, Konstantinos; Schulze, Matthias; Gunter, Marc; Murphy, Neil; Castells, Antoni; Castellvi-Bel, Sergi; Moreira, Leticia; Arndt, Volker; Shcherbina, Anna; Stern, Mariana; Pardamean, Bens; Bishop, Timothy; Giles, Graham; Southey, Melissa; Idos, Gregory; McDonnell, Kevin; Abu-Ful, Zomoroda; Greenson, Joel; Shulman, Katerina; Lejbkowicz, Flavio; Offit, Kenneth; Su, Yu-Ru; Steinfelder, Robert; Keku, Temitope; van Guelpen, Bethany; Hudson, Thomas; Hampel, Heather; Pearlman, Rachel; Berndt, Sonja; Hayes, Richard; Martinez, Marie Elena; Thomas, Sushma; Corley, Douglas; Pharoah, Paul; Larsson, Susanna; Yen, Yun; Lenz, Heinz-Josef; White, Emily; Li, Li; Doheny, Kimberly; Pugh, Elizabeth; Shelford, Tameka; Chan, Andrew; Cruz-Correa, Marcia; Lindblom, Annika; Hunter, David; Joshi, Amit; Schafmayer, Clemens; Scacheri, Peter; Kundaje, Anshul; Nickerson, Deborah; Schoen, Robert; Hampe, Jochen; Stadler, Zsofia; Vodicka, Pavel; Vodickova, Ludmila; Vymetalkova, Veronika; Papadopoulos, Nickolas; Edlund, Chistopher; Gauderman, William; Thomas, Duncan; Shibata, David; Toland, Amanda; Markowitz, Sanford; Kim, Andre; Chanock, Stephen; van Duijnhoven, Franzel; Feskens, Edith; Sakoda, Lori; Gago-Dominguez, Manuela; Wolk, Alicja; Naccarati, Alessio; Pardini, Barbara; FitzGerald, Liesel; Lee, Soo Chin; Ogino, Shuji; Bien, Stephanie; Kooperberg, Charles; Li, Christopher; Lin, Yi; Prentice, Ross; Qu, Conghui; Bezieau, Stephane; Tangen, Catherine; Mardis, Elaine; Yamaji, Taiki; Sawada, Norie; Iwasaki, Motoki; Haiman, Christopher; Le Marchand, Loic; Wu, Anna; Qu, Chenxu; McNeil, Caroline; Coetzee, Gerhard; Hayward, Caroline; Deary, Ian; Harris, Sarah; Theodoratou, Evropi; Reid, Stuart; Walker, Marion; Ooi, Li Yin; Moreno, Victor; Casey, Graham; Gruber, Stephen; Tomlinson, Ian; Zheng, Wei; Dunlop, Malcolm; Houlston, Richard; Peters, Ulrike Share Save
Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries Fernandez-Rozadilla, Ceres; Timofeeva, Maria; Chen, Zhishan; Law, Philip; Thomas, Minta; Bien, Stephanie; Diez-Obrero, Virginia; Li, Li; Fernandez-Tajes, Juan; Palles, Claire; Sherwood, Kitty; Harris, Sarah; Svinti, Victoria; McDonnell, Kevin; Farrington, Susan; Studd, James; Vaughan-Shaw, Peter; Shu, Xiao-ou; Long, Jirong; Cai, Qiuyin; Guo, Xingyi; Lu, Yingchang; Scacheri, Peter; Studd, James; Huyghe, Jeroen; Harrison, Tabitha; Shibata, David; Haiman, Christopher; Devall, Mathew; Schumacher, Fredrick; Melas, Marilena; Rennert, Gad; Obon-Santacana, Mireia; Martin-Sanchez, Vicente; Moratalla-Navarro, Ferran; Oh, Jae Hwan; Kim, Jeongseon; Jee, Sun Ha; Jung, Keum Ji; Kweon, Sun-Seog; Shin, Min-Ho; Shin, Aesun; Ahn, Yoon-Ok; Kim, Dong-Hyun; Oze, Isao; Wen, Wanqing; Matsuo, Keitaro; Matsuda, Koichi; Tanikawa, Chizu; Ren, Zefang; Gao, Yu-Tang; Jia, Wei-Hua; Potter, John; Jenkins, Mark; Win, Aung Ko; Pai, Rish; Figueiredo, Jane; Haile, Robert; Gallinger, Steven; Woods, Michael; Newcomb, Polly; Shibata, David; Cheadle, Jeremy; Kaplan, Richard; Maughan, Timothy; Kerr, Rachel; Kerr, David; Kirac, Iva; Boehm, Jan; Mecklin, Lukka-Pekka; Jousilahti, Pekka; Knekt, Paul; Aaltonen, Lauri; Rissanen, Harri; Pukkala, Eero; Eriksson, Johan; Cajuso, Tatiana; Hanninen, Ulrika; Kondelin, Johanna; Palin, Kimmo; Tanskanen, Tomas; Renkonen-Sinisalo, Laura; Zanke, Brent; Mannisto, Satu; Albanes, Demetrius; Weinstein, Stephanie; Ruiz-Narvaez, Edward; Palmer, Julie; Buchanan, Daniel; Platz, Elizabeth; Visvanathan, Kala; Ulrich, Cornelia; Siegel, Erin; Brezina, Stefanie; Gsur, Andrea; Campbell, Peter; Chang-Claude, Jenny; Hoffmeister, Michael; Brenner, Hermann; Slattery, Martha; Potter, John; Tsilidis, Konstantinos; Schulze, Matthias; Gunter, Marc; Murphy, Neil; Castells, Antoni; Castellvi-Bel, Sergi; Moreira, Leticia; Arndt, Volker; Shcherbina, Anna; Stern, Mariana; Pardamean, Bens; Bishop, Timothy; Giles, Graham; Southey, Melissa; Idos, Gregory; McDonnell, Kevin; Abu-Ful, Zomoroda; Greenson, Joel; Shulman, Katerina; Lejbkowicz, Flavio; Offit, Kenneth; Su, Yu-Ru; Steinfelder, Robert; Keku, Temitope; van Guelpen, Bethany; Hudson, Thomas; Hampel, Heather; Pearlman, Rachel; Berndt, Sonja; Hayes, Richard; Martinez, Marie Elena; Thomas, Sushma; Corley, Douglas; Pharoah, Paul; Larsson, Susanna; Yen, Yun; Lenz, Heinz-Josef; White, Emily; Li, Li; Doheny, Kimberly; Pugh, Elizabeth; Shelford, Tameka; Chan, Andrew; Cruz-Correa, Marcia; Lindblom, Annika; Shibata, David; Joshi, Amit; Schafmayer, Clemens; Scacheri, Peter; Kundaje, Anshul; Nickerson, Deborah; Schoen, Robert; Hampe, Jochen; Stadler, Zsofia; Vodicka, Pavel; Vodickova, Ludmila; Vymetalkova, Veronika; Papadopoulos, Nickolas; Edlund, Chistopher; Gauderman, William; Thomas, Duncan; Shibata, David; Toland, Amanda; Markowitz, Sanford; Kim, Andre; Gruber, Stephen; van Duijnhoven, Franzel; Feskens, Edith; Sakoda, Lori; Gago-Dominguez, Manuela; Wolk, Alicja; Naccarati, Alessio; Pardini, Barbara; FitzGerald, Liesel; Lee, Soo Chin; Ogino, Shuji; Bien, Stephanie; Kooperberg, Charles; Li, Christopher; Lin, Yi; Prentice, Ross; Qu, Conghui; Bezieau, Stephane; Tangen, Catherine; Mardis, Elaine; Yamaji, Taiki; Sawada, Norie; Iwasaki, Motoki; Haiman, Christopher; Le Marchand, Loic; Wu, Anna; Qu, Chenxu; McNeil, Caroline; Coetzee, Gerhard; Hayward, Caroline; Deary, Ian; Harris, Sarah; Theodoratou, Evropi; Reid, Stuart; Walker, Marion; Ooi, Li Yin; Moreno, Victor; Casey, Graham; Gruber, Stephen; Tomlinson, Ian; Zheng, Wei; Dunlop, Malcolm; Houlston, Richard; Peters, Ulrike Share Save
CXD101 and nivolumab in patients with metastatic microsatellite-stable colorectal cancer (CAROSELL): a multicentre, open-label, single-arm, phase II trial Saunders, M. P.; Graham, J.; Cunningham, D.; Plummer, R.; Church, D.; Kerr, R.; Cook, S.; Zheng, S.; La Thangue, N.; Kerr, D. Share Save
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