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Shigeo Murata

The University of Tokyo

69H-index
303Paper Count
2.6WCitation Count
Published Papers 112
Publication Date
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The homozygous founder Psmb8 variant of Nakajo-Nishimura syndrome/proteasome-associated autoinflammatory syndrome causes panniculitis-associated lipoatrophy and a shortened lifespan in mice
errScientific Reports
IF3.9
err2026-05-28
err0
errOAAI
errTomoyuki Hara; Akira Kinoshita; Jun Hamazaki; Hiroaki Hemmi; Takashi Kato; Izumi Sasaki; Yutaka Inaba; Yusuke Yamashita; Daisuke Okuzaki; Koh-Ichiro Yoshiura; Shigeo Murata; Masatoshi Jinnin; Tsuneyasu Kaisho; Nobuo Kanazawa
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Proteasome alteration between epithelial and hematopoietic cells facilitates positive selection of CD8 T cells
errNature Communications
IF15.7
err2026-04-27
err0
errOAAI
errMami Matsuda-Lennikov; Jamie-Jean De La Torre; Todd Snow; Jacqueline Battaile; Felix Kalle-Youngoue; Alison Jacques; Aya Ushio; Akihide Shimizu; Miho Shinzawa; Christian T. Mayer; Parirokh Awasthi; Raj Chari; Izumi Ohigashi; Shigeo Murata; Yousuke Takahama
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errSave
Recent Insights into Mechanisms Regulating the Proteasome: Implications for Human Disease
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2025-11-01
err0
PREAI
errSumikama, Rintaro; Shibata, Yuri; Wu, Rihan; Murata, Shigeo
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errSave
Proteasomal regulation of ASK family kinases dictates cell fate under hyperosmotic stress
errJournal of Biological Chemistry
IF3.9
err2025-08-06
err0
errOAAI
errXiangyu Zhou; Kengo Watanabe; Kazuhiro Morishita; Jun Hamazaki; Shigeo Murata; Isao Naguro; Hidenori Ichijo
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errSave
Microaggrephagy: an ESCRT-I-PTPN23-dependent pathway for MAPT/tau aggregate clearance
errAutophagy
IF14.3
err2025-07-06
err0
PREAI
errShoshiro Hirayama; Shigeo Murata
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errSave
Keiji Tanaka (1949-2024)
errMOLECULAR CELL
IF16.6
err2024-12-01
err0
PREAI
errMurata, S; Iwai, K
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errSave
Keiji Tanaka (1949-2024)
errCELL
IF42.5
err2024-12-01
err0
PREAI
errMurata, Shigeo; Iwai, Kazuhiro
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errSave
Intrinsic signaling pathways modulate targeted protein degradation
errNATURE COMMUNICATIONS
IF15.7
err2024-07-02
err2
errOAAI
errMori, Yuki; Akizuki, Yoshino; Honda, Rikuto; Takao, Miyu; Tsuchimoto, Ayaka; Hashimoto, Sota; Iio, Hiroaki; Kato, Masakazu; Kaiho-Soma, Ai; Saeki, Yasushi; Hamazaki, Jun; Murata, Shigeo; Ushijima, Toshikazu; Hattori, Naoko; Ohtake, Fumiaki
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Senescent cells form nuclear foci that contain the 26S proteasome
errCELL REPORTS
IF6.9
err2023-08-01
err7
errOAAI
errIriki, Tomohiro; Iio, Hiroaki; Yasuda, Shu; Masuta, Shun; Kato, Masakazu; Kosako, Hidetaka; Hirayama, Shoshiro; Endo, Akinori; Ohtake, Fumiaki; Kamiya, Mako; Urano, Yasuteru; Saeki, Yasushi; Hamazaki, Jun; Murata, Shigeo
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Rpn10-mediated degradation of ubiquitinated proteins is essential for mouse development
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err106
errOAAI
errHamazaki, Jun; Sasaki, Katsuhiro; Kawahara, Hiroyuki; Hisanaga, Shin-ichi; Tanaka, Keiji; Murata, Shigeo
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errSave
Genetic Evidence Linking Age-Dependent Attenuation of the 26S Proteasome with the Aging Process
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-21
err252
errOAAI
errTonoki, Ayako; Kuranaga, Erina; Tomioka, Takeyasu; Hamazaki, Jun; Murata, Shigeo; Tanaka, Keiji; Miura, Masayuki
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errSave
PAC1 Gene Knockout Reveals an Essential Role of Chaperone-Mediated 20S Proteasome Biogenesis and Latent 20S Proteasomes in Cellular Homeostasis
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err41
errOAAI
errSasaki, Katsuhiro; Hamazaki, Jun; Koike, Masato; Hirano, Yuko; Komatsu, Masaaki; Uchiyama, Yasuo; Tanaka, Keiji; Murata, Shigeo
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errSave
N-Terminal α7 Deletion of the Proteasome 20S Core Particle Substitutes for Yeast PI31 Function
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err14
errOAAI
errYashiroda, Hideki; Toda, Yousuke; Otsu, Saori; Takagi, Kenji; Mizushima, Tsunehiro; Murata, Shigeo
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errSave
Proteasome Impairment Induces Recovery of Mitochondrial Membrane Potential and an Alternative Pathway of Mitochondrial Fusion
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-17
err8
errOAAI
errShirozu, Ryohei; Yashiroda, Hideki; Murata, Shigeo
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errSave
NRF3-POMP-20S Proteasome Assembly Axis Promotes Cancer Development via Ubiquitin-Independent Proteolysis of p53 and Retinoblastoma Protein
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-03
err33
errOAAI
errWaku, Tsuyoshi; Nakamura, Nanami; Koji, Misaki; Watanabe, Hidenori; Katoh, Hiroki; Tatsumi, Chika; Tamura, Natsuko; Hatanaka, Atsushi; Hirose, Shuuhei; Katayama, Hiroyuki; Tani, Misato; Kubo, Yuki; Hamazaki, Jun; Hamakubo, Takao; Watanabe, Akira; Murata, Shigeo; Kobayashi, Akira
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errSave
Ubiquitin-Binding Protein CG5445 Suppresses Aggregation and Cytotoxicity of Amyotrophic Lateral Sclerosis-Linked TDP-43 in Drosophila
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-03
err10
errOAAI
errUechi, Hiroyuki; Kuranaga, Erina; Iriki, Tomohiro; Takano, Kohei; Hirayama, Shoshiro; Miura, Masayuki; Hamazaki, Jun; Murata, Shigeo
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errSave
Specific Modification of Aged Proteasomes Revealed by Tag-Exchangeable Knock-In Mice
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-03
err19
errOAAI
errTomita, Takuya; Hirayama, Shoshiro; Sakurai, Yasuyuki; Ohte, Yuki; Yoshihara, Hidehito; Saeki, Yasushi; Hamazaki, Jun; Murata, Shigeo
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errSave
The effect of nutrient deprivation on proteasome activity in 4-week-old mice and 24-week-old mice
errJOURNAL OF NUTRITIONAL BIOCHEMISTRY
IF4.9
err2022-07-01
err1
PREAI
errTanahashi, Nobuyuki; Komiyama, Moeko; Tanaka, Mina; Yokobori, Yuta; Murata, Shigeo; Tanaka, Keiji
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The Molecular Mechanisms Governing the Assembly of the Immuno- and Thymoproteasomes in the Presence of Constitutive Proteasomes
errCELLS
IF5.2
err2022-05-07
err9
errOAAI
errWatanabe, Ayaka; Yashiroda, Hideki; Ishihara, Satoshi; Lo, Megan; Murata, Shigeo
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errSave
Heterozygous missense variant of the proteasome subunit β-type 9 causes neonatal-onset autoinflammation and immunodeficiency
errNATURE COMMUNICATIONS
IF15.7
err2021-11-24
err26
errOAAI
errKanazawa, Nobuo; Hemmi, Hiroaki; Kinjo, Noriko; Ohnishi, Hidenori; Hamazaki, Jun; Mishima, Hiroyuki; Kinoshita, Akira; Mizushima, Tsunehiro; Hamada, Satoru; Hamada, Kazuya; Kawamoto, Norio; Kadowaki, Saori; Honda, Yoshitaka; Izawa, Kazushi; Nishikomori, Ryuta; Tsumura, Miyuki; Yamashita, Yusuke; Tamura, Shinobu; Orimo, Takashi; Ozasa, Toshiya; Kato, Takashi; Sasaki, Izumi; Fukuda-Ohta, Yuri; Wakaki-Nishiyama, Naoko; Inaba, Yutaka; Kunimoto, Kayo; Okada, Satoshi; Taketani, Takeshi; Nakanishi, Koichi; Murata, Shigeo; Yoshiura, Koh-ichiro; Kaisho, Tsuneyasu
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Research Directions

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Co-authors
Cooperation Journals
S
Shizuo Akira
H-index: 269 · Papers: 1.5K
N
Noboru Mizushima
H-index: 141 · Papers: 423
K
Keiji Tanaka
H-index: 127 · Papers: 554
W
Wolfgang Baumeister
H-index: 125 · Papers: 729
Y
Yoshinori Ohsumi
H-index: 117 · Papers: 341
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