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Michael P. Rout

Rockefeller University

76H-index
486Paper Count
2.2WCitation Count
Published Papers 123
Publication Date
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Breaking barriers: Respiratory viral strategies targeting the host's nuclear pore complex and nuclear transport pathways
errMolecular Biology of the Cell
IF2.7
err2026-02-01
err0
PREAI
errUdi, Yael; Aitchison, John D.; Rout, Michael P.; Obado, Samson
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errSave
Division of labor in trypanosome RNA processing and export through expanded Mex67 paralogs
errNucleic Acids Research
IF13.1
err2026-01-13
err0
PREAI
errObado, Samson O.; Fridy, Peter C.; Hegedusova, Eva; van Eeuwen, Trevor; Stein, Milana E.; Zhang, Wenzhu; Jensen, Bryan C.; Chung, Connor; Brillantes, Marc; Glover, Lucy; Paris, Zdenek; Chait, Brian T.; Field, Mark C.; Rout, Michael P.
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errSave
Karyopherins remodel the dynamic organization of the nuclear pore complex transport barrier
errNature Cell Biology
IF19.1
err2025-12-02
err0
errOAAI
errToshiya Kozai; Javier Fernandez-Martinez; Larisa E. Kapinos; Paola Gallardo; Trevor van Eeuwen; Martin Saladin; Roi Eliasian; Adam Mazur; Wenzhu Zhang; Jeremy Tempkin; Radhakrishnan Panatala; Maria Delgado-Izquierdo; Raul Escribano-Marin; Qingzhou Feng; Chenxiang Lin; Andrej Sali; Brian T. Chait; Barak Raveh; Liesbeth M. Veenhoff; Michael P. Rout; Roderick Y. H. Lim
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errSave
Rapid DNA Cleavage by the LINE-1 Endonuclease Proximal to DNA Ends and at Mismatches
errJournal of Biological Chemistry
IF3.9
err2025-11-29
err0
errOAAI
errBryant D. Miller; Benedict A. Smail; Trevor Van Eeuwen; Hanna Kodama; Kazuma Kondo; Hua Jiang; Allison O’Brien; Nan Dai; Robert J. Trachman; Shengxi Guan; Jennifer A. Karlow; Wen-Chih Cheng; John M. Sedivy; Gerwald Jogl; Michael P. Rout; John LaCava; Kathleen H. Burns; Martin S. Taylor
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errSave
Unique mechanisms to increase structural stability and enhance antigen binding in nanobodies
errSTRUCTURE
IF4.3
err2025-02-01
err0
PREAI
errKetaren, Natalia E.; Fridy, Peter C.; Malashkevich, Vladimir; Sanyal, Tanmoy; Brillantes, Marc; Thompson, Mary K.; Oren, Deena A.; Bonanno, Jeffrey B.; Sali, Andrej; Almo, Steven C.; Chait, Brian T.; Rout, Michael P.
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errSave
Nanobodies: From High-Throughput Identification to Therapeutic Development
errMOLECULAR & CELLULAR PROTEOMICS
IF5.5
err2024-12-01
err1
errOAAI
errFridy, Peter C.; Rout, Michael P.; Ketaren, Natalia E.
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errSave
A new generation of nanobody research tools using improved mass spectrometry-based discovery methods
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-09-01
err0
errOAAI
errFridy, Peter C.; Farrell, Ryan J.; Molloy, Kelly R.; Keegan, Sarah; Wang, Junjie; Jacobs, Erica Y.; Li, Yinyin; Trivedi, Jill; Sehgal, Viren; Fenyo, David; Wu, Zhuhao; Chait, Brian T.; Rout, Michael P.
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errSave
Nanobody repertoire generated against the spike protein of ancestral SARS-CoV-2 remains efficacious against the rapidly evolving virus
errELIFE
IF0
err2024-05-07
err2
errOAAI
errKetaren, Natalia E.; Mast, Fred D.; Fridy, Peter C.; Olivier, Jean Paul; Sanyal, Tanmoy; Sali, Andrej; Chait, Brian T.; Rout, Michael P.; Aitchison, John D.
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errSave
Ultrasensitive Detection of Circulating LINE-1 ORF1p as a Specific Multicancer Biomarker
errCANCER DISCOVERY
IF33.3
err2023-09-12
err19
errOAAI
errTaylor, Martin S.; Wu, Connie; Fridy, Peter C.; Zhang, Stephanie J.; Senussi, Yasmeen; Wolters, Justina C.; Cajuso, Tatiana; Cheng, Wen-Chih; Heaps, John D.; Miller, Bryant D.; Mori, Kei; Cohen, Limor; Jiang, Hua; Molloy, Kelly R.; Chait, Brian T.; Goggins, Michael G.; Bhan, Irun; Franses, Joseph W.; Yang, Xiaoyu; Taplin, Mary-Ellen; Wang, Xinan; Christiani, David C.; Johnson, Bruce E.; Meyerson, Matthew; Uppaluri, Ravindra; Egloff, Ann Marie; Denault, Elyssa N.; Spring, Laura M.; Wang, Tian-Li; Shih, Ie-Ming; Fairman, Jennifer E.; Jung, Euihye; Arora, Kshitij S.; Yilmaz, Osman H.; Cohen, Sonia; Sharova, Tatyana; Chi, Gary; Norden, Bryanna L.; Song, Yuhui; Nieman, Linda T.; Pappas, Leontios; Parikh, Aparna R.; Strickland, Matthew R.; Corcoran, Ryan B.; Mustelin, Tomas; Eng, George; Yilmaz, OEmer H.; Matulonis, Ursula A.; Chan, Andrew T.; Skates, Steven J.; Rueda, Bo R.; Drapkin, Ronny; Klempner, Samuel J.; Deshpande, Vikram; Ting, David T.; Rout, Michael P.; LaCava, John; Walt, David R.; Burns, Kathleen H.
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errSave
Implications of a multiscale structure of the yeast nuclear pore complex
errMOLECULAR CELL
IF16.6
err2023-09-01
err6
errOAAI
errAkey, Christopher W.; Echeverria, Ignacia; Ouch, Christna; Nudelman, Ilona; Shi, Yi; Wang, Junjie; Chait, Brian T.; Sali, Andrej; Fernandez-Martinez, Javier; Rout, Michael P.
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errSave
Nuclear pore complexes mediate subtelomeric gene silencing by regulating PCNA levels on chromatin
errJOURNAL OF CELL BIOLOGY
IF6.4
err2023-06-26
err8
errOAAI
errKumar, Sanjeev; Neal, Maxwell L.; Li, Song; Navare, Arti T.; Van Eeuwen, Trevor; Wozniak, Richard W.; Mast, Fred D.; Rout, Michael P.; Aitchison, John D.
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errSave
Improving the hole picture: towards a consensus on the mechanism of nuclear transport
errBIOCHEMICAL SOCIETY TRANSACTIONS
IF4.3
err2023-04-26
err18
errOAAI
errCowburn, David; Rout, Michael
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errSave
Depicting protein structures as schematics
errTRENDS IN BIOCHEMICAL SCIENCES
IF11
err2023-04-01
err0
errOAAI
errMarkert, Jonathan; Luger, Karolin; Lee, Hayun; Hu, Haidai; Taylor, Nicholas M. I.; Fernandez-Martinez, Javier; Rout, Michael; Alder, Nathan
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errSave
Kap121p-mediated nuclear import is required for mating and cellular differentiation in yeast
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err51
errOAAI
errLeslie, DM; Grill, B; Rout, MP; Wozniak, RW; Aitchison, JD
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errSave
Characterization of karyopherin cargoes reveals unique mechanisms of kap121p-mediated nuclear import
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err60
errOAAI
errLeslie, DM; Zhang, WZ; Timney, BL; Chait, BT; Rout, MP; Wozniak, RW; Aitchison, JD
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errSave
A general method for quantitative fractionation of mammalian cells
errJOURNAL OF CELL BIOLOGY
IF6.4
err2023-03-15
err1
errOAAI
errUdi, Yael; Zhang, Wenzhu; Stein, Milana E. E.; Ricardo-Lax, Inna; Pasolli, Hilda A. A.; Chait, Brian T. T.; Rout, Michael P. P.
errShare
errSave
Expanding and improving nanobody repertoires using a yeast display method: Targeting SARS-CoV-2
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-03-01
err12
errOAAI
errCross, Frederick R.; Fridy, Peter C.; Ketaren, Natalia E.; Mast, Fred D.; Li, Song; Olivier, J. Paul; Pecani, Kresti; Chait, Brian T.; Aitchison, John D.; Rout, Michael P.
errShare
errSave
Nup170-mediated subtelomeric gene silencing occurs via regulation of PCNA levels on DNA
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-01-01
err0
errOAAI
errAitchison, John; Kumar, Sanjeev; Neal, Maxwell; Li, Song; Navare, Arti; Mast, Fred; Rout, Michael
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errSave
Highly synergistic combinations of nanobodies that target SARS-CoV-2 reduce viral load in hACE2 transgenic mice
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-01-01
err0
errOAAI
errOlivier, Paul; Mast, Fred; Fridy, Peter; Ketaren, Natalia; Miller, Leslie; Sanyal, Tanmoy; Rout, Michael; Chait, Brian; Aitchison, John
errShare
errSave
Coatomer in the universe of cellular complexity
errMOLECULAR BIOLOGY OF THE CELL
IF2.7
err2022-12-01
err7
errOAAI
errField, Mark C.; Rout, Michael P.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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Matthew Meyerson
H-index: 223 · Papers: 1.9K
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Michel C. Nussenzweig
H-index: 183 · Papers: 617
C
Charles M. Rice
H-index: 166 · Papers: 718
A
Andrew T. Chan
H-index: 135 · Papers: 2.2K
M
Michael Goggins
H-index: 132 · Papers: 1.1K
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