Iris H. Jonkers - Publications, H-index & Citations

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Iris H. Jonkers

Genetics

29H-index

104Paper Count

5.2KCitation Count

Published Papers 40

Publication Date

A multidisciplinary RNA-guided approach to complement genomic analysis of unsolved patients with an inborn error of immunity

Frontiers in Immunology

IF5.9

2026-05-28

OAAI

WT Willem T. K. Maassen † ‡; LC Lotte C. E. T. Pape † ‡; TN Tim Niemeijer † ‡; AH Anne-Margriet Heijink; MT Martine T. Meems-Veldhuis ‡; DJ Daniëlle J. Boerrigter; GV Gerben van der Vries ‡; HW Helga Westers ‡; LF Lennart F. Johansson ‡; KJ Kasper J. van der Velde ‡; MA Morris A. Swertz ‡; LF Lude Franke; GE Geertje E. Legger ‡; AJ Annechien J. A. Lambeck; AR Abraham Rutgers ‡; IH Iris H. Jonkers ‡; ME Mariëlle E. van Gijn ‡; EZ Evelien Zonneveld-Huijssoon ‡

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A model for predicting celiac disease among undiagnosed subjects established with data from the HUNT4 study

BMC Gastroenterology

IF2.6

2026-04-16

OAAI

Mohammad Sayeef Alam; Rebecka Hjort; Iris H. Jonkers; Sebo Withoff; Kristian Hveem; Knut E. A. Lundin; Ludvig M. Sollid; Eivind Ness-Jensen

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Human gut M cells resemble dendritic cells and present gluten antigen

Nature

IF48.5

2025-12-10

PREAI

Daisong Wang; Sangho Lim; Willine J. van de Wetering; Carmen Lopez-Iglesias; Yuu Okura; Yuri Teranishi-Ikawa; Akihiko Mizoroki; Willem Kasper Spoelstra; Talya Dayton; Gijs J. F. van Son; Apollo Pronk; Niels Smakman; Gieneke B. C. Gonera-de Jong; Sebo Withoff; Iris H. Jonkers; Jeroen S. van Zon; Sander J. Tans; Peter J. Peters; Johan H. van Es; Hans Clevers

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Gene expression profiling reveals enhanced nutrient and drug metabolism and maturation of hiPSC-derived intestine-on-chip relative to organoids and Transwells

Stem Cell Reports

IF5.1

2025-11-13

OAAI

Renée Moerkens; Joram Mooiweer; Eline Smits; Marijn Berg; Aarón D. Ramírez-Sánchez; Rutger Modderman; Jens Puschhof; Cayetano Pleguezuelos-Manzano; Robert J. Barrett; Cisca Wijmenga; Iris H. Jonkers; Sebo Withoff

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Cytokine-induced memory-like responses in endothelial cells link chronic inflammation to vascular disease risk

Mol. Omics

IF0

2025-10-14

OAAI

Kieu T. T. Le †; Nick Keur †; Heleen Middelkamp †; Thuy Linh Do; Albert van den Berg; Valeria Orlova; Leo A.B. Joosten; Mihai G. Netea; Cisca Wijmenga; Iris Jonkers ‡; Sebo Withoff ‡; Andries D. Van der Meer ‡; Vinod Kumar ‡

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Genetic differences between diagnosed and undiagnosed Celiac disease: a population-based study

Human Genetics

IF3.6

2025-09-29

OAAI

Mohammad Sayeef Alam; Brooke N. Wolford; Kristian Hveem; Knut E. A. Lundin; Sebo Withoff; Iris H. Jonkers; Ludvig M. Sollid; Rebecka Hjort; Eivind Ness-Jensen

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Transcriptomics and eQTLs reveal inflammatory heterogeneity in the duodenal lining in coeliac disease

genes and immunity

IF0

2025-09-09

OAAI

Aarón D. Ramírez-Sánchez; Stephanie Zühlke; Raúl Aguirre-Gamboa; Martijn Vochteloo; Lude Franke; Knut E. A. Lundin; Sebo Withoff; Iris H. Jonkers

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Low butyrate concentrations exert anti-inflammatory and high concentrations exert pro-inflammatory effects on macrophages

nutritional biochemistry

IF0

2025-05-15

PREAI

Muwei Jiang; Danny Incarnato; Rutger Modderman; Aina Altimira Lazaro; Iris H. Jonkers; Frans Bianchi; Geert van den Bogaart

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High-resolution analysis of the treated coeliac disease microbiome reveals strain-level variation

GUT MICROBES

IF11

2025-04-27

OAAI

Jelle Slager; Hanna L. Simpson; Ranko Gacesa; Lianmin Chen; Ineke L. Tan; Jody Gelderloos; Astrid Maatman; Cisca Wijmenga; Alexandra Zhernakova; Jingyuan Fu; Rinse K. Weersma; Gieneke Gonera; Iris H. Jonkers; Sebo Withoff

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Shared Genetics in Celiac Disease and Inflammatory Bowel Disease Specify a Greater Role for Intestinal Epithelial Cells

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IF4.9

2025-03-25

OAAI

Ribeiro, Nathan Vinicius; Anwar, Sajid; Withoff, Sebo; Jonkers, Iris H.

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Identification of rare disease genes as drivers of common diseases through tissue-specific gene regulatory networks

SCIENTIFIC REPORTS

IF3.9

2024-12-04

OAAI

Bakker, Olivier B.; Claringbould, Annique; Westra, Harm-Jan; Wiersma, Henry; Boulogne, Floranne; Vosa, Urmo; Urzua-Traslavina, Carlos G.; Symmons, Sophie Mulcahy; Zidan, Mahmoud M. M.; Sadler, Marie C.; Kutalik, Zoltan; Jonkers, Iris H.; Franke, Lude; Deelen, Patrick

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An iPSC-derived small intestine-on-chip with self-organizing epithelial, mesenchymal, and neural cells

CELL REPORTS

IF6.9

2024-07-01

OAAI

Moerkens, Renee; Mooiweer, Joram; Ramirez-Sanchez, Aaron D.; Oelen, Roy; Franke, Lude; Wijmenga, Cisca; Barrett, Robert J.; Jonkers, Iris H.; Withoff, Sebo

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Potential biomarkers for multiple sclerosis stage from targeted proteomics and microRNA sequencing

BRAIN COMMUNICATIONS

IF4.5

2024-06-13

OAAI

Tan, Ineke L.; Modderman, Rutger; Stachurska, Anna; Almeida, Rodrigo; de Vries, Riemer; Heersema, Dorothea J.; Gacesa, Ranko; Wijmenga, Cisca; Jonkers, Iris H.; Meilof, Jan F.; Withoff, Sebo

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Genetic mapping across autoimmune diseases reveals shared associations and mechanisms

NATURE GENETICS

IF31.8

2024-05-13

PREAI

Lincoln, Matthew R.; Connally, Noah; Axisa, Pierre-Paul; Gasperi, Christiane; Mitrovic, Mitja; van Heel, David; Wijmenga, Cisca; Withoff, Sebo; Jonkers, Iris H.; Padyukov, Leonid; Beecham, Ashley H.; Patsopoulos, Nikolaos A.; Cotsapas, Chris; Booth, David; Goris, An; Oturai, Annette; Saarela, Janna; Fontaine, Betrand; Hemmer, Bertrand; Claes, Martin; Zipp, Frauke; D'Alfonso, Sandra; Martinelli-Boneschi, Filippo; Taylor, Bruce; Harbo, Hanne F.; Kockum, Ingrid; Hillert, Jan; Olsson, Tomas; Oksenberg, Jorge R.; Hintzen, Rogier; Barcellos, Lisa F.; Alfredsson, Lars; Esposito, Federica; Martin, Roland; Haines, Jonathan L.; Pericak-Vance, Margaret A.; Ivinson, Adrian J.; Stewart, Graeme; Hafler, David; Hauser, Stephen L.; Compston, Alastair; Mcvean, Gil; De Jager, Philip; Sawcer, Stephen J.; Mccauley, Jakob L.; Rich, Stephen S.; Graham, Robert R.; Gaffney, Patrick M.; Langefeld, Carl D.; Vyse, Timothy J.; Hafler, David A.; Chun, Sung; Sunyaev, Shamil R.; Cotsapas, Chris

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Antigen-driven colonic inflammation is associated with development of dysplasia in primary sclerosing cholangitis

NATURE MEDICINE

IF50

2023-06-15

OAAI

Shaw, Dustin G.; Aguirre-Gamboa, Raul; Vieira, Marcos C.; Gona, Saideep; DiNardi, Nicholas; Wang, Anni; Dumaine, Anne; Gelderloos-Arends, Jody; Earley, Zachary M.; Meckel, Katherine R.; Ciszewski, Cezary; Castillo, Anabella; Monroe, Kelly; Torres, Joana; Shah, Shailja C.; Colombel, Jean-Frederic; Itzkowitz, Steven; Newberry, Rodney; Cohen, Russell D.; Rubin, David T.; Quince, Christopher; Cobey, Sarah; Jonkers, Iris H.; Weber, Christopher R.; Pekow, Joel; Wilson, Patrick C.; Barreiro, Luis B.; Jabri, Bana

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Phage display sequencing reveals that genetic, environmental, and intrinsic factors influence variation of human antibody epitope repertoire

IMMUNITY

IF26.3

2023-06-01

OAAI

Andreu-Sanchez, Sergio; Bourgonje, Arno R.; Vogl, Thomas; Kurilshikov, Alexander; Leviatan, Sigal; Ruiz-Moreno, Angel J.; Hu, Shixian; Sinha, Trishla; Vila, Arnau Vich; Klompus, Shelley; Kalka, Iris N.; de Leeuw, Karina; Arends, Suzanne; Jonkers, Iris; Withoff, Sebo; Brouwer, Elisabeth; Weinberger, Adina; Wijmenga, Cisca; Segal, Eran; Weersma, Rinse K.; Fu, Jingyua; Zhernakova, Alexandra

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It takes a village: STATs control IE-CTL pathogenesis in Celiac Disease

JOURNAL OF IMMUNOLOGY

IF3.4

2023-05-01

OAAI

Borregard, Megan Elisabeth; Broekema, Roeland; Jonkers, Iris; Jabri, Bana

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iPSC-derived organ-on-a-chip models for personalized human genetics and pharmacogenomics studies

TRENDS IN GENETICS

IF16.3

2023-04-01

OAAI

Palasantzas, Victoria E. J. M.; Tamargo-Rubio, Isabel; Le, Kieu; Slager, Jelle; Wijmenga, Cisca; Jonkers, Iris H.; Kumar, Vinod; Fu, Jingyuan; Withoff, Sebo

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Xist RNA is confined to the nuclear territory of the silenced X chromosome throughout the cell cycle

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Jonkers, Iris; Monkhorst, Kim; Rentmeester, Eveline; Grootegoed, J. Anton; Grosveld, Frank; Gribnau, Joost

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Gut mucosa dissociation protocols influence cell type proportions and single-cell gene expression levels

SCIENTIFIC REPORTS

IF3.9

2022-06-14

OAAI

Venema, Werna T. C. Uniken; Ramirez-Sanchez, Aaron D.; Bigaeva, Emilia; Withoff, Sebo; Jonkers, Iris; McIntyre, Rebecca E.; Ghouraba, Mennatallah; Raine, Tim; Weersma, Rinse K.; Franke, Lude; Festen, Eleonora A. M.; van der Wijst, Monique G. P.

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Research Directions