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The long and winding road to biomarkers for immunotherapy: a retrospective analysis of samples from patients with triple-negative breast cancer treated with pembrolizumab Buisseret, L.; Bareche, Y.; Venet, D.; Girard, E.; Gombos, A.; Emonts, P.; Majjaj, S.; Rouas, G.; Serra, M.; Debien, V.; Agostinetto, E.; Garaud, S.; Willard-Gallo, K.; Larsimont, D.; Stagg, J.; Rothe, F.; Sotiriou, C. Share Save
DT-9045, a novel PAR2 inhibitor with best-in-class properties that reduces resistance to both EGFR-targeting therapies and immunotherapy in oncology models Brugat, Thibaut; Kadiri, Maleck; Aouad, Samya; Blayo, Anne-Laure; Rugeri, Baptiste; Mousson, Antoine; Janvier, Aurelie; Steinberg, Edith; Baron, Luc; Recolet, Mandy; Wirth, Xavier; Garcia-Leon, Maria Jesus; Ruet, Quentin; Semache, Meriem; Sabbagh, Laurent; Blanchard, Orphee; Franchet, Christel; Mayer, Stanislas; Stagg, John; Lenne, Nathalie; Schann, Stephan Share Save
Paclitaxel plus carboplatin and durvalumab with or without oleclumab for women with previously untreated locally advanced or metastatic triple-negative breast cancer: the randomized SYNERGY phase I/II trial Buisseret, Laurence; Loirat, Delphine; Aftimos, Philippe; Maurer, Christian; Punie, Kevin; Debien, Veronique; Kristanto, Paulus; Eiger, Daniel; Goncalves, Anthony; Ghiringhelli, Francois; Taylor, Donatienne; Clatot, Florent; Van den Mooter, Tom; Ferrero, Jean-Marc; Bonnefoi, Herve; Canon, Jean-Luc; Duhoux, Francois P.; Mansi, Laura; Poncin, Renaud; Barthelemy, Philippe; Isambert, Nicolas; Denis, Zoe; Catteau, Xavier; Salgado, Roberto; Agostinetto, Elisa; de Azambuja, Evandro; Rothe, Francoise; Craciun, Ligia; Venet, David; Romano, Emanuela; Stagg, John; Paesmans, Marianne; Larsimont, Denis; Sotiriou, Christos; Ignatiadis, Michail; Piccart-Gebhart, Martine Share Save
A pan-cancer clinical platform to predict immunotherapy outcomes and prioritize immuno-oncology combinations in early-phase trials Hernando-Calvo, Alberto; Vila-Casadesus, Maria; Bareche, Yacine; Gonzalez-Medina, Alberto; Abbas-Aghababazadeh, Farnoosh; Lo Giacco, Deborah; Martin, Agatha; Saavedra, Omar; Brana, Irene; Vieito, Maria; Fasani, Roberta; Stagg, John; Mancuso, Francesco; Haibe-Kains, Benjamin; Han, Ming; Berche, Roger; Pugh, Trevor J.; Mirallas, Oriol; Jimenez, Jose; Gonzalez, Nadia Saoudi; Valverde, Claudia; Munoz-Couselo, Eva; Suarez, Cristina; Diez, Marc; Elez, Elena; Capdevila, Jaume; Oaknin, Ana; Saura, Cristina; Macarulla, Teresa; Galceran, Joan Carles; Felip, Enriqueta; Dienstmann, Rodrigo; Bedard, Philippe L.; Nuciforo, Paolo; Seoane, Joan; Tabernero, Josep; Garralda, Elena; Vivancos, Ana Share Save
Adenosine A2A receptor is a tumor suppressor of NASH-associated hepatocellular carcinoma Allard, Bertrand; Jacoberger-Foissac, Celia; Cousineau, Isabelle; Bareche, Yacine; Buisseret, Laurence; Chrobak, Pavel; Allard, David; Pommey, Sandra; Ah-Pine, Franck; Duquenne, Sebastien; Picard, Fabien; Stagg, John Share Save
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Radiomics using computed tomography to predict CD73 expression and prognosis of colorectal cancer liver metastases Saber, Ralph; Henault, David; Messaoudi, Nouredin; Rebolledo, Rolando; Montagnon, Emmanuel; Soucy, Genevieve; Stagg, John; Tang, An; Turcotte, Simon; Kadoury, Samuel Share Save
Updates on radiotherapy-immunotherapy combinations: Proceedings of 6th annual ImmunoRad conference Gregucci, Fabiana; Spada, Sheila; Barcellos-Hoff, Mary Helen; Bhardwaj, Nina; Hak, Charleen Chan Wah; Fiorentino, Alba; Guha, Chandan; Guzman, Monica L.; Harrington, Kevin; Herrera, Fernanda G.; Honeychurch, Jamie; Hong, Theodore; Iturri, Lorea; Jaffee, Elisabeth; Karam, Sana D.; Knott, Simon R. V.; Koumenis, Constantinos; Lyden, David; Marciscano, Ariel E.; Melcher, Alan; Mondini, Michele; Mondino, Anna; Morris, Zachary S.; Pitroda, Sean; Quezada, Sergio A.; Santambrogio, Laura; Shiao, Stephen; Stagg, John; Telarovic, Irma; Timmerman, Robert; Vozenin, Marie-Catherine; Weichselbaum, Ralph; Welsh, James; Wilkins, Anna; Xu, Chris; Zappasodi, Roberta; Zou, Weiping; Bobard, Alexandre; Demaria, Sandra; Galluzzi, Lorenzo; Deutsch, Eric; Formenti, Silvia C. Share Save
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Novel biased PAR2 inhibitors with best-in-class properties reduce resistance to both chemotherapy and immunotherapy in oncology models Brugat, Thibaut; Bergami, Francesco; Rugeri, Baptiste; Janvier, Aurelie; Steinberg, Edith; Baron, Luc; Recolet, Mandy; Wirth, Xavier; Semache, Meriem; Mousson, Antoine; Dietsch, Camille; Ruet, Quentin; Blanchard, Orphee; Jacoberger-Foissac, Celia; Cousineau, Isabelle; Kadiri, Maleck; Blayo, Anne-Laure; Franchet, Christel; Mayer, Stanislas; Stagg, John; Lenne, Nathalie; Schann, Stephan Share Save
Leveraging big data of immune checkpoint blockade response identifies novel potential targets Bareche, Y.; Kelly, D.; Abbas-Aghababazadeh, F.; Nakano, M.; Esfahani, P. N.; Tkachuk, D.; Mohammad, H.; Samstein, R.; Lee, C. -H.; Morris, L. G. T.; Bedard, P. L.; Haibe-Kains, B.; Stagg, J. Share Save
IL27 Signaling Serves as an Immunologic Checkpoint for Innate Cytotoxic Cells to Promote Hepatocellular Carcinoma Aghayev, Turan; Mazitova, Aleksandra M.; Fang, Jennifer R.; Peshkova, Iuliia O.; Rausch, Matthew; Hung, Manhsih; White, Kerry F.; Masia, Ricard; Titerina, Elizaveta K.; Fatkhullina, Aliia R.; Cousineau, Isabelle; Turcotte, Simon; Zhigarev, Dmitry; Marchenko, Anastasiia; Khoziainova, Svetlana; Makhov, Petr; Tan, Yin Fei; Kossenkov, Andrew, V; Wiest, David L.; Stagg, John; Wang, Xin Wei; Campbell, Kerry S.; Dzutsev, Amiran K.; Trinchieri, Giorgio; Hill, Jonathan A.; Grivennikov, Sergei I.; Koltsova, Ekaterina K. Share Save
Spatially mapping the immune landscape of melanoma using imaging mass cytometry Moldoveanu, Dan; Ramsay, LeeAnn; Lajoie, Mathieu; Anderson-Trocme, Luke; Lingrand, Marine; Berry, Diana; Perus, Lucas J. M.; Wei, Yuhong; Moraes, Cleber; Alkallas, Rached; Rajkumar, Shivshankari; Zuo, Dongmei; Dankner, Matthew; Xu, Eric Hongbo; Bertos, Nicholas R.; Najafabadi, Hamed S.; Gravel, Simon; Costantino, Santiago; Richer, Martin J.; Lund, Amanda W.; Del Rincon, Sonia V.; Spatz, Alan; Miller, Wilson H., Jr.; Jamal, Rahima; Lapointe, Rejean; Mes-Masson, Anne-Marie; Turcotte, Simon; Petrecca, Kevin; Dumitra, Sinziana; Meguerditchian, Ari-Nareg; Richardson, Keith; Tremblay, Francine; Wang, Beatrice; Chergui, May; Guiot, Marie-Christine; Watters, Kevin; Stagg, John; Quail, Daniela F.; Mihalcioiu, Catalin; Meterissian, Sarkis; Watson, Ian R. Share Save
Prognostic implications of adaptive immune features in MMR-proficient colorectal liver metastases classified by histopathological growth patterns Messaoudi, Nouredin; Henault, David; Stephen, David; Cousineau, Isabelle; Simoneau, Eve; Rong, Zhixia; Letourneau, Richard; Plasse, Marylene; Dagenais, Michel; Roy, Andre; Lapointe, Real; Vandenbroucke-Menu, Franck; Kunda, Rastislav; Ysebaert, Dirk; Soucy, Genevieve; Stagg, John; Vermeulen, Peter; Turcotte, Simon Share Save
DNA hypomethylating agents increase activation and cytolytic activity of CD8+T cells Yau, Helen Loo; Bell, Emma; Ettayebi, Ilias; de Almeida, Felipe Campos; Boukhaled, Giselle M.; Shen, Shu Yi; Allard, David; Morancho, Beatriz; Marhon, Sajid A.; Ishak, Charles A.; Gonzaga, Isabela M.; Medina, Tiago da Silva; Singhania, Rajat; Chakravarthy, Ankur; Chen, Raymond; Mehdipour, Parinaz; Pommey, Sandra; Klein, Christian; Amarante-Mendes, Gustavo P.; Roulois, David; Arribas, Joaquin; Stagg, John; Brooks, David G.; De Carvalho, Daniel D. Share Save
1-Methylnicotinamide is an immune regulatory metabolite in human ovarian cancer Kilgour, Marisa K.; MacPherson, Sarah; Zacharias, Lauren G.; Ellis, Abigail E.; Sheldon, Ryan D.; Liu, Elaine Y.; Keyes, Sarah; Pauly, Brenna; Carleton, Gillian; Allard, Bertrand; Smazynski, Julian; Williams, Kelsey S.; Watson, Peter H.; Stagg, John; Nelson, Brad H.; DeBerardinis, Ralph J.; Jones, Russell G.; Hamilton, Phineas T.; Lum, Julian J. Share Save
INCREASED SERUM LEVELS OF EBI3 ARE ASSOCIATED WITH POOR OUTCOME IN HEPATOCELLULAR CARCINOMA PATIENTS AND SRF388, A FIRST-IN-CLASS IL-27 BLOCKING ANTIBODY, INHIBITS THE GROWTH OF MURINE LIVER TUMORS Rausch, Matthew; Moodley, Devapregasan; Peluso, Marisa; Koseoglu, Secil; Hua, Jing; Tan, Gege; Masia, Ricard; Lee, Benjamin; Cousineau, Isabelle; Turcotte, Simon; Stagg, John; Palombella, Vito; Holland, Pamela; Hill, Jonathan Share Save
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