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Christophe Le Tourneau

Institut Curie

67H-index
630Paper Count
2.3WCitation Count
Published Papers 219
Publication Date
A viral-based individualized neoantigen vaccine as adjuvant treatment in resected head and neck squamous cell carcinoma: a randomized Phase I trial
err2026-08-17
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errChristian Ottensmeier; Jean-Pierre Delord; Ana Lalanne; Camille Jamet; Anne-Laure Le Gac; Katell Bidet Huang; Benoît Grellier; Jules Deforges; Maud Brandely; Eric Quéméneur; Bérangère Bastien; Annette Tavernaro; Gisèle Lacoste; Valérie Schoettel; Clémentine Spring-Giusti; Nathalie Silvestre; Jean-Baptiste Marchand; Sylvain Robin; Emmanuelle Dochy; Maurizio Ceppi; Alessandro Riva; Naoko Yamagata; Per Brattas; Kazuhide Onoguchi; Yoshiko Yamashita; Hugues Fontenelle; Mariana Eggert Martinez; Oliver Baker; Terry Jones; Andrew Schache; Eliane Piaggio; Kaïdre Bendjama; Olivier Lantz; Christophe Le Tourneau
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Development and external validation of a prognostic score associated with poor outcomes in patients receiving immune checkpoint blockade-containing therapies enrolled in early-phase clinical trials
err2026-07-01
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PREAI
errMatte, Paul; Alshatti, Nael; Roulleaux-Dugage, Matthieu; Fahrner, Jean-Eudes; Baldini, Capucine; Champiat, Stephane; Vasseur, Damien; Ouali, Kaissa; Gazzah, Anas; Bahleda, Rastislav; Bayle, Arnaud; Postel-Vinay, Sophie; Sakkal, Madona; Michot, Jean-Marie; Hollebecque, Antoine; Chaput, Nathalie; Loriot, Yohann; Deutsch, Eric; Italiano, Antoine; Vaflard, Pauline; Dupain, Celia; Le Tourneau, Christophe; Massard, Christophe; Marabelle, Aurelien; Danlos, Francois-Xavier
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Efficacy of buparlisib according to PIK3CA mutation status in recurrent or metastatic head and neck squamous cell carcinoma: A multicenter phase II trial
err2026-05-13
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PREAI
errThibault Gauduchon; Laurence Digue; Céline Ferlay; Isabelle Treilleux; Qing Wang; Valéry Attignon; Gautier Lefebvre; Nuria Kotecki; Amaury Daste; Caroline Even; Sophie Couchon-Thaunat; Aurélie Guyennon; Frédéric Peyrade; Didier Cupissol; Benoît You; Christophe Le Tourneau; Séverine Tabone-Eglinger; Gwenaelle Garin; David Pérol; Jérome Fayette
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Accelerating recruitment in clinical trials: A strategic challenge
err2026-01-01
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PREAI
errDeplanque, Dominique; Galaup, Ariane; Trillou, Christine; Barthelemy, Philippe; Bayle, Arnaud; Da Cruz, Lionel; Domain, Erik; Duruisseaux, Michael; Fouret, Cecile; Gambotti, Laetitia; Girault, Cecile; Gonthier, Damien; Guerin, Aurelie; Hommais, Antoine; Hulot, Jean-Sebastien; Ko, Dorothee; Lang, Marie; Laugel, Vincent; Laviolle, Bruno; Le Tourneau, Christophe; Oheix, Julie; Simon, Tabassome; Skrzypski, Jeremy
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Benchmarking progression-free survival ratio as primary endpoint in precision oncology clinical trials
err2025-12-15
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errFederico Nichetti; Jennifer Hüllein; Pauline du Rusquec; Erin Pleasance; Li Chen; Andreas Mock; Peter Horak; Paolo Ambrosini; Simone Rota; Monica Niger; Luca Agnelli; Gabriele Tinè; Dominic Edelmann; Christophe Le Tourneau; Janessa Laskin; Giancarlo Pruneri; Chi Wang; Daniel Hübschmann; Filippo de Braud; Stefan Fröhling; Luigi Mariani
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Management and survival of patients with cancer of unknown primary discussed by a French national multidisciplinary tumour board: a retrospective analysis
err2025-11-07
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errCélia Dupain; Nicolas Jacquin; Aurélien Latouche; Zoé Nevière; Pierre Gestraud; Abderaouf Hamza; Kenza Nedara; Vincent Cockenpot; Janick Selves; Yves Allory; Laëtitia Chanas; Maud Milder; Isabelle Soubeyran; Hélène Blons; Anna Patrikidou; Axel de Bernardi; Julien Masliah-Planchon; Odette Mariani; Etienne Rouleau; Fabienne Escande; Sandrine Boyault; Pierre Saintigny; Florence de Fraipont; Pierre Blanc; Jennifer Wong; Camille Tlemsani; Isabelle Guillou; Julie Flavius; Noemie Fuentealba; Maud Kamal; Ivan Bièche; Nicolas Servant; Christophe Le Tourneau; Sarah Watson
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MOVIE phase II trial of tremelimumab plus durvalumab combined with metronomic oral vinorelbine in patients with head and neck cancer
err2025-11-06
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errE. Borcoman; A. Hervieu; C. Cropet; E. Coquan; J. Guigay; F. Rolland; M. Bernadach; E. Charafe; F. Legrand; E. Dassé; C. Le Tourneau; A. Gonçalves
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Acceptance of external control arms by HTA agencies: a review of oncology submissions in France, England, Germany and Norway from 2021 to 2023
err2025-09-12
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PREAI
errMatthias Monnereau; Jean-Pierre Delord; Stefan Michiels; Christophe Le Tourneau; Sebastien Marque; Louise Baschet; Thomas Filleron
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Molecular analysis of lung adenocarcinomas from the SAFIR02-Lung cohort reveals new metastasis-associated copy-number alterations including frequent mutant-specific KRAS-allelic imbalance and identifies CDKN2A homozygous deletions as an independent biomarker of poor prognosis
err2025-09-11
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PREAI
errAbderaouf Hamza; Pierre Gestraud; Maryam Karimi; Alicia Tran-Dien; Laurène Syx; Sophie Vacher; Quentin Peretti; Ludovic Lacroix; Valery Attignon; Isabelle Soubeyran; Pascal Jézéquel; David Planchard; Samia Melaabi; Trenton Dailey-Chwalibóg; Marta Jimenez; Stefan Michiels; Nicolas Servant; Christophe Le Tourneau; Nicolas Girard; Fabrice André; Benjamin Besse; Maud Kamal; Fabrice Barlesi; Ivan Bièche
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Efficacy of pembrolizumab and vorinostat combination in patients with recurrent and/or metastatic squamous cell carcinomas: a phase 2 basket trial
err2025-06-30
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errEdith Borcoman; Bastien Cabarrou; Miguel Francisco; Frédéric Bigot; François Ghiringhelli; Damien Vansteene; François Legrand; Maral Halladjian; Célia Dupain; Olivia Le Saux; Clelia Coutzac; Christian Borel; Raphael Chaltiel; Benoit You; Carlos Gomez-Roca; Sophie Cousin; Elodie Coquan; Aurélien Lambert; Esma Saada-Bouzid; Xavier Durando; Mathilde Saint-Ghislain; Gianmaria Frige; Elena Guerini-Rocco; Maria Manuela Tonini; Ivan Bièche; Zahra Castel-Ajgal; Grégoire Marret; Marie-Paule Sablin; Emmanuelle Jeannot; Fabrice Andre; Thomas Filleron; Marta Jimenez; Luca Mazzarella; Nicolas Servant; Maud Kamal; Christophe Le Tourneau
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Clinical landscape for patients with head and neck cancers enrolled in phase I trials at a tertiary referral center
err2025-06-30
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errDaria Maria Filippini; Raphael Sanchez; Etienne Bastien; Nicolas Jacquin; Alexandro Paccapelo; Caroline Nhy; Jerzy Klijanienko; Valentin Calugaru; Anne Chilles; Wahib Ghanem; Guillaume Rougier; Antoine Dubray Vautrin; Nathalie Badois; Maria Lesnik; Olivier Choussy; Marie Paule Sablin; Christophe Le Tourneau; Grégoire Marret
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Multicollinearity and redundancy of the PET radiomic feature set
err2025-05-07
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errNoortman, Wyanne A.; Vriens, Dennis; Bussink, Johan; Meijer, Tineke W. H.; Aarntzen, Erik H. J. G.; Deroose, Christophe M.; Lhommel, Renaud; Aide, Nicolas; Le Tourneau, Christophe; de Koster, Elizabeth J.; Oyen, Wim J. G.; Triemstra, Lianne; Ruurda, Jelle P.; Vegt, Erik; de Geus-Oei, Lioe-Fee; van Velden, Floris H. P.
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A phase II study of monalizumab and durvalumab in patients with recurrent/metastatic squamous cell carcinoma of the head and neck: results of the I2 cohort of the EORTC-HNCG-1559 trial (UPSTREAM)
err2025-05-01
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errGalot, R.; Le Tourneau, C.; Licitra, L.; Guigay, J.; Kong, A.; Tinhofer, I.; Even, C.; Daste, A.; Henry, S.; Borel, C.; Abdeddaim, C.; Seront, E.; Prevost, J. B.; Rutten, A.; Saada-Bouzid, E.; Rolland, F.; Bonomo, P.; Rasschaert, M.; Dirix, L.; Olungu, C.; Tsechilidou, K.; Govaerts, A. S.; Fortpied, C.; Joaquim, A.; Machiels, J. P.
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Deciphering molecular relapse and intra-tumor heterogeneity in non-metastatic resectable head and neck squamous cell carcinoma using circulating tumor DNA
err2025-01-01
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PREAI
errMarret, Gregoire; Lamy, Constance; Vacher, Sophie; Cabel, Luc; Sene, Mathieu; Ahmanache, Ladidi; Courtois, Laura; El Beaino, Zakhia; Klijanienko, Jerzy; Martinat, Charlotte; Servant, Nicolas; Kamoun, Choumouss; Halladjian, Maral; Bronzini, Thierry; Balsat, Cedric; Laes, Jean-Francois; Prevot, Aubray; Sauvage, Sebastien; Lienard, Maxime; Martin, Emmanuel; Genin, Berengere; Badois, Nathalie; Lesnik, Maria; Dubray-Vautrin, Antoine; Choussy, Olivier; Ghanem, Wahib; Taouachi, Rabah; Planchon, Julien Masliah; Bieche, Ivan; Le Tourneau, Christophe; Kamal, Maud
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Paving the path towards tissue-agnostic drug approval in oncology
err2024-11-01
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PREAI
errLe Tourneau, C.; Bieche, I.; Kamal, M.
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Comprehensive biomarker and modeling approach to support dose finding for BI 836880, a VEGF/Ang-2 inhibitor
err2024-10-14
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errKeller, Sascha; Kunz, Ulrich; Schmid, Ulrike; Beusmans, Jack; Buechert, Martin; He, Min; Jayadeva, Girish; Le Tourneau, Christophe; Luedtke, Doreen; Niessen, Heiko G.; Oum'hamed, Zohra; Pleiner, Sina; Wang, Xiaoning; Graeser, Ralph
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Methylation, Gene Expression, and Risk Genotypes at the TERT-CLPTM1L Locus in Cervical Cancer
err2024-10-01
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PREAI
errRamachandran, Dhanya; Mao, Qianqian; Liao, Dandan; Kamal, Maud; Schuermann, Peter; Eisenblaetter, Rieke; Geffers, Robert; Balint, Balazs; Lecompte, Lolita; Servant, Nicolas; Cherif, Linda Larbi; Lamy, Constance; Baulande, Sylvain; Legoix, Patricia; Le Tourneau, Christophe; Latouche, Aurelien; Hillemanns, Peter; Scholl, Suzy; Doerk, Thilo
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Evasion of apoptosis and treatment resistance in squamous cell carcinoma of the head and neck
err2024-09-01
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errOAAI
errO'Leary, Ben; Skinner, Heath; Schoenfeld, Jonathan; Licitra, Lisa; Le Tourneau, Christophe; Esdar, Christina; Schroeder, Andreas; Salmio, Satu; Psyrri, Amanda
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Next-generation sequencing (NGS) in routine care: Medical practice in 24 countries from the pan-cancer WAYFIND-R registry
err2024-09-01
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PREAI
errLe Tourneau, C.; Dienstmann, R.; Hackshaw, A.; Geissler, J.; Ferro, A.; Cheese, E.; Schirghuber, E.; Blay, J-Y.
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