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Gradual changes within long-lived influenza virus-specific CD8+ T cells are associated with the loss of public TCR clonotypes in older adults van de Sandt, Carolien E.; McQuilten, Hayley A.; Aban, Malet; Nguyen, Thi H. O.; Valkenburg, Sophie A.; Grant, Emma J.; Sant, Sneha; Rossjohn, Jamie; Gras, Stephanie; Crowe, Jane; Kedzierska, Katherine Share Save
Molecular determinants of cross-strain influenza A virus recognition by αβ T cell receptors Quinones-Parra, Sergio M.; Gras, Stephanie; Nguyen, Thi H. O.; Farenc, Carine; Szeto, Christopher; Rowntree, Louise C.; Chaurasia, Priyanka; Sant, Sneha; Boon, Adrianus C. M.; Jayasinghe, Dhilshan; Rimmelzwaan, Guus F.; Petersen, Jan; Doherty, Peter C.; Uldrich, Adam P.; Littler, Dene R. Share Save
Newborn and child-like molecular signatures in older adults stem from TCR shifts across human lifespan van de Sandt, Carolien E.; Nguyen, Thi H. O.; Gherardin, Nicholas A.; Crawford, Jeremy Chase; Samir, Jerome; Minervina, Anastasia A.; Pogorelyy, Mikhail V.; Rizzetto, Simone; Szeto, Christopher; Kaur, Jasveen; Ranson, Nicole; Sonda, Sabrina; Harper, Alice; Redmond, Samuel J.; McQuilten, Hayley A.; Menon, Tejas; Sant, Sneha; Jia, Xiaoxiao; Pedrina, Kate; Karapanagiotidis, Theo; Cain, Natalie; Nicholson, Suellen; Chen, Zhenjun; Lim, Ratana; Clemens, E. Bridie; Eltahla, Auda; La Gruta, Nicole L.; Crowe, Jane; Lappas, Martha; Rossjohn, Jamie; Godfrey, Dale I.; Thomas, Paul G.; Gras, Stephanie; Flanagan, Katie L.; Luciani, Fabio; Kedzierska, Katherine Share Save
Combined PARP and WEE1 inhibition triggers anti-tumor immune response in BRCA1/2 wildtype triple-negative breast cancer Teo, Zhi Ling; O'Connor, Mark J.; Versaci, Stephanie; Clarke, Kylie A.; Brown, Emmaline R.; Percy, Luke W.; Kuykhoven, Keilly; Mintoff, Christopher P.; Savas, Peter; Virassamy, Balaji; Luen, Stephen J.; Byrne, Ann; Sant, Sneha; Lindeman, Geoffrey J.; Darcy, Phillip K.; Loi, Sherene Share Save
Tucatinib promotes immune activation and synergizes with programmed cell death-1 and programmed cell death-ligand 1 inhibition in HER2-positive breast cancer Li, Ran; Sant, Sneha; Brown, Emmaline; Caramia, Franco; Nikolic, Bronte; Clarke, Kylie; Byrne, Ann; Gonzalez, Luis E. Lara; Savas, Peter; Luen, Stephen J.; Teo, Zhi Ling; Virassamy, Balaji; Neeson, Paul J.; Darcy, Phillip K.; Loi, Sherene Share Save
SPEN is a biomarker for CDK4/6 inhibitor resistance in patients with metastatic hormone receptor positive (HR+)/HER2-breast cancer Van Geelen, Courtney T.; Teo, Zhi Ling; Savas, Peter; Luen, Stephen J.; Clarke, Kylie A.; Sant, Sneha; Cowley, Karla J.; Caramia, Franco; Simpson, Kaylene J.; Andre, Fabrice; Dawson, Sarah-Jane; Pearson, Richard; Loi, Sherene Share Save
Checkpoint inhibitor immunotherapy diminishes oocyte number and quality in mice Winship, Amy L.; Alesi, Lauren R.; Sant, Sneha; Stringer, Jessica M.; Cantavenera, Aldana; Hegarty, Teharn; Requesens, Carolina Lliberos; Liew, Seng H.; Sarma, Urooza; Griffiths, Meaghan J.; Zerafa, Nadeen; Fox, Stephen B.; Brown, Emmaline; Caramia, Franco; Zareie, Pirooz; La Gruta, Nicole L.; Phillips, Kelly-Anne; Strasser, Andreas; Loi, Sherene; Hutt, Karla J. Share Save
Immune cellular networks underlying recovery from influenza virus infection in acute hospitalized patients Nguyen, Thi H. O.; Koutsakos, Marios; van de Sandt, Carolien E.; Crawford, Jeremy Chase; Loh, Liyen; Sant, Sneha; Grzelak, Ludivine; Allen, Emma K.; Brahm, Tim; Clemens, E. Bridie; Auladell, Maria; Hensen, Luca; Wang, Zhongfang; Nussing, Simone; Jia, Xiaoxiao; Gunther, Patrick; Wheatley, Adam K.; Kent, Stephen J.; Aban, Malet; Deng, Yi-Mo; Laurie, Karen L.; Hurt, Aeron C.; Gras, Stephanie; Rossjohn, Jamie; Crowe, Jane; Xu, Jianqing; Jackson, David; Brown, Lorena E.; La Gruta, Nicole; Chen, Weisan; Doherty, Peter C.; Turner, Stephen J.; Kotsimbos, Tom C.; Thomas, Paul G.; Cheng, Allen C.; Kedzierska, Katherine Share Save
HLA-B*27:05 alters immunodominance hierarchy of universal influenza-specific CD8+T cells Sant, Sneha; Quinones-Parra, Sergio M.; Koutsakos, Marios; Grant, Emma J.; Loudovaris, Thomas; Mannering, Stuart I.; Crowe, Jane; van de Sandt, Carolien E.; Rimmelzwaan, Guus F.; Rossjohn, Jamie; Gras, Stephanie; Loh, Liyen; Nguyen, Thi H. O.; Kedzierska, Katherine Share Save
Human Mucosal-Associated Invariant T Cells in Older Individuals Display Expanded TCRαβ Clonotypes with Potent Antimicrobial Responses Loh, Liyen; Gherardin, Nicholas A.; Sant, Sneha; Grzelak, Ludivine; Crawford, Jeremy Chase; Bird, Nicola L.; Koay, Hui-Fern; van de Sandt, Carolien E.; Moreira, Marcela L.; Lappas, Martha; Allen, E. Kaitlynn; Crowe, Jane; Loudovaris, Thomas; Flanagan, Katie L.; Quinn, Kylie M.; Rossjohn, Jamie; Thomas, Paul G.; Eckle, Sidonia B. G.; McCluskey, James; Godfrey, Dale I.; Kedzierska, Katherine Share Save
Tissue-resident memory T cells in breast cancer control and immunotherapy responses Byrne, Ann; Savas, Peter; Sant, Sneha; Li, Ran; Virassamy, Balaji; Luen, Stephen J.; Beavis, Paul A.; Mackay, Laura K.; Neeson, Paul J.; Loi, Sherene Share Save
Challenging immunodominance of influenza-specific CD8+ T cell responses restricted by the risk-associated HLA-A*68:01 allomorph van de Sandt, C. E.; Clemens, E. B.; Grant, E. J.; Rowntree, L. C.; Sant, S.; Halim, H.; Crowe, J.; Cheng, A. C.; Kotsimbos, T. C.; Richards, M.; Miller, A.; Tong, S. Y. C.; Rossjohn, J.; Nguyen, T. H. O.; Gras, S.; Chen, W.; Kedzierska, K. Share Save
Divergent SATB1 expression across human life span and tissue compartments Nussing, Simone; Koay, Hui-Fern; Sant, Sneha; Loudovaris, Thomas; Mannering, Stuart I.; Lappas, Martha; d'Udekem, Yves; Konstantinov, Igor E.; Berzins, Stuart P.; Rimmelzwaan, Guus F.; Turner, Stephen J.; Clemens, E. Bridie; Godfrey, Dale I.; Thi HO Nguyen; Kedzierska, Katherine Share Save
Human CD8+ T cell cross-reactivity across influenza A, B and C viruses Koutsakos, Marios; Illing, Patricia T.; Nguyen, Thi H. O.; Mifsud, Nicole A.; Crawford, Jeremy Chase; Rizzetto, Simone; Eltahla, Auda A.; Clemens, E. Bridie; Sant, Sneha; Chua, Brendon Y.; Wong, Chinn Yi; Allen, E. Kaitlynn; Teng, Don; Dash, Pradyot; Boyd, David F.; Grzelak, Ludivine; Zeng, Weiguang; Hurt, Aeron C.; Barr, Ian; Rockman, Steve; Jackson, David C.; Kotsimbos, Tom C.; Cheng, Allen C.; Richards, Michael; Westall, Glen P.; Loudovaris, Thomas; Mannering, Stuart I.; Elliott, Michael; Tangye, Stuart G.; Wakim, Linda M.; Rossjohn, Jamie; Vijaykrishna, Dhanasekaran; Luciani, Fabio; Thomas, Paul G.; Gras, Stephanie; Purcell, Anthony W.; Kedzierska, Katherine Share Save
Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans Grant, Emma J.; Josephs, Tracy M.; Loh, Liyen; Clemens, E. Bridie; Sant, Sneha; Bharadwaj, Mandvi; Chen, Weisan; Rossjohn, Jamie; Gras, Stephanie; Kedzierska, Katherine Share Save
MAIT cells contribute to a protective antiviral innate response to influenza infection Hinks, Timothy; van Wilgenburg, Bonnie; Loh, Liyen; Chen, Zhenjun; Pediongco, Troi; Wang, Huimeng; Shi, Mai; Zhao, Zhe; Koutsakos, Marios; Nussing, Simone; Sant, Sneha; Wang, Zhongfang; D'Souza, Criselle; Almeida, Catarina; Reading, Patrick; Corbett, Alexandra; Mccluskey, James; Klenerman, Paul; Kedzierska, Katherine Share Save
MAIT CELLS CONTRIBUTE TO A PROTECTIVE ANTIVIRAL INNATE RESPONSE TO INFLUENZA INFECTION Hinks, T. S. C.; van Wilgenburg, B.; Loh, L.; Pediongco, T. J.; Wang, H.; Shi, M.; Zhao, Z.; Koutsakos, M.; Nussing, S.; Sant, S.; Wang, Z.; D'Souza, C.; Almeida, C. F.; Reading, P.; Corbett, A. J.; McCluskey, J.; Klenerman, P.; Kedzierska, K. Share Save
MAIT cells contribute to protection against lethal influenza infection in vivo van Wilgenburg, Bonnie; Loh, Liyen; Chen, Zhenjun; Pediongco, Troi J.; Wang, Huimeng; Shi, Mai; Zhao, Zhe; Koutsakos, Marios; Nussing, Simone; Sant, Sneha; Wang, Zhongfang; D'Souza, Criselle; Jia, Xiaoxiao; Almeida, Catarina F.; Kostenko, Lyudmila; Eckle, Sidonia B. G.; Meehan, Bronwyn S.; Kallies, Axel; Godfrey, Dale I.; Reading, Patrick C.; Corbett, Alexandra J.; McCluskey, James; Klenerman, Paul; Kedzierska, Katherine; Hinks, Timothy S. C. Share Save
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