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Nicolas Plachta

University of Pennsylvania

27H-index
79Paper Count
2.9KCitation Count
Published Papers 32
Publication Date
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Live imaging captures the events immediately following fertilization
errDevelopmental Cell
IF8.7
err2026-07-17
err0
PREAI
errRobin M. Skory; Ana Domingo-Muelas; Sarah Declercq; Winter Vandenberghe; Piotr Tetlak; Blake Hernandez; Dominic Stoop; Colin C. Conine; Maté Biro; Björn Heindryckx; Nicolas Plachta
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Modeling human embryo adhesion using a microfluidic platform
errScience Advances
IF12.5
err2026-07-10
err0
errOAAI
errSofía Zaragozano; María Pardo-Figuerez; Ana Monteagudo-Sanchez; Anna Quirant; Javier Moncayo-Arlandi; Javier Gonzalez-Fernandez; Jaime Llera-Oyola; Petr Volkov; Sara Maggi; Luis Quintero; Francisco Raga; Pablo Grases; Xavier Santamaria; Inmaculada Moreno; Nicolas Plachta; Carlos Simon; Felipe Vilella
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errSave
Capturing aberrant cell behaviors producing defects in human embryos via live imaging
errScience Advances
IF12.5
err2025-11-19
err0
PREAI
errHiroki Akizawa; Ana Domingo-Muelas; Maria Pardo-Figuerez; Blake Hernandez; Goli Ardestani; Robin M. Skory; Marta Venturas; Piotr Tetlak; Stephanie Bissiere; Denny Sakkas; Carlos Simon; Nicolas Plachta
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errSave
Actin organizes chromosomes and microtubules to ensure mitotic fidelity in the preimplantation embryo
errSCIENCE
IF45.8
err2025-05-22
err0
PREAI
errHernandez, Blake; Tetlak, Piotr; Domingo-Muelas, Ana; Akizawa, Hiroki; Skory, Robin M.; Ardestani, Goli; Biro, Mate; Liu, Xiaolei; Bissiere, Stephanie; Sakkas, Denny; Plachta, Nicolas
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Pretreatment with IL-15 and IL-18 rescues natural killer cells from granzyme B-mediated apoptosis after cryopreservation
errNATURE COMMUNICATIONS
IF15.7
err2024-05-10
err5
errOAAI
errBerjis, Abdulla; Muthumani, Deeksha; Aguilar, Oscar A.; Pomp, Oz; Johnson, Omar; Finck, Amanda V.; Engel, Nils W.; Chen, Linhui; Plachta, Nicolas; Scholler, John; Lanier, Lewis L.; June, Carl H.; Sheppard, Neil C.
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errSave
Human Embryo Live Imaging Reveals Nuclear DNA Shedding During Blastocyst Expansion and Biopsy
errOBSTETRICAL & GYNECOLOGICAL SURVEY
IF3.6
err2023-10-01
err0
PREAI
errDomingo-Muelas, Ana; Skory, Robin M.; Moverley, Adam A.; Ardestani, Goli; Pomp, Oz; Rubio, Carmen; Tetlak, Piotr; Hernandez, Blake; Rhon-Calderon, Eric A.; Navarro-Sanchez, Luis; Garcia-Pascual, Carmen M.; Bissiere, Stephanie; Bartolomei, Marisa S.; Sakkas, Denny; Simon, Carlos; Plachta, Nicolas
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errSave
Shedding light on stem cells: Optogenetics uncover the role of ERK dynamics in pluripotency
errDEVELOPMENTAL CELL
IF8.7
err2023-06-01
err0
errOAAI
errMoverley, Adam A.; Plachta, Nicolas
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errSave
The nuclear lamina couples mechanical forces to cell fate in the preimplantation embryo via actin organization
errNATURE COMMUNICATIONS
IF15.7
err2023-05-29
err13
errOAAI
errSkory, Robin M.; Moverley, Adam A.; Ardestani, Goli; Alvarez, Yanina; Domingo-Muelas, Ana; Pomp, Oz; Hernandez, Blake; Tetlak, Piotr; Bissiere, Stephanie; Stern, Claudio D.; Sakkas, Denny; Plachta, Nicolas
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errSave
The trophectoderm acts as a niche for the inner cell mass through C/EBPa-regulated IL-6 signaling
errSTEM CELL REPORTS
IF5.1
err2022-09-01
err5
errOAAI
errPlana-Carmona, Marcos; Stik, Gregoire; Bulteau, Romain; Segura-Morales, Carolina; Alcazar, Noelia; Wyatt, Chris D. R.; Klonizakis, Antonios; de Andres-Aguayo, Luisa; Gasnier, Maxime; Tian, Tian, V; Torcal Garcia, Guillem; Vila-Casadesus, Maria; Plachta, Nicolas; Serrano, Manuel; Francesconi, Mirko; Graf, Thomas
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A monoastral mitotic spindle determines lineage fate and position in the mouse embryo
errNATURE CELL BIOLOGY
IF19.1
err2022-01-31
err17
PREAI
errPomp, Oz; Lim, Hui Yi Grace; Skory, Robin M.; Moverley, Adam A.; Tetlak, Piotr; Bissiere, Stephanie; Plachta, Nicolas
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errSave
Cytoskeletal control of early mammalian development
errNATURE REVIEWS MOLECULAR CELL BIOLOGY
IF90.2
err2021-04-29
err43
PREAI
errLim, Hui Yi Grace; Plachta, Nicolas
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errSave
Emerging mechanisms driving cell differentiation in vivo
errCURRENT OPINION IN CELL BIOLOGY
IF4.3
err2020-12-01
err0
PREAI
errNiessen, Carien M.; Plachta, Nicolas A.
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errSave
Novel approaches to link apicobasal polarity to cell fate specification
errCURRENT OPINION IN CELL BIOLOGY
IF4.3
err2020-02-01
err8
PREAI
errMotegi, Fumio; Plachta, Nicolas; Viasnoff, Virgile
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errSave
Specification of the First Mammalian Cell Lineages In Vivo and In Vitro
errcold spring harbor perspectives in medicine
IF8.4
err2019-10-15
err18
errOAAI
errWhite, Melanie D.; Plachta, Nicolas
errShare
errSave
Instructions for Assembling the Early Mammalian Embryo
errDEVELOPMENTAL CELL
IF8.7
err2018-06-01
err79
errOAAI
errWhite, Melanie D.; Zenker, Jennifer; Bissiere, Stephanie; Plachta, Nicolas
errShare
errSave
Dynamic Fluctuations in Subcellular Localization of the Hippo Pathway Effector Yorkie In Vivo
errCURRENT BIOLOGY
IF7.5
err2018-05-01
err69
errOAAI
errManning, Samuel A.; Dent, Lucas G.; Kondo, Shu; Zhao, Ziqing W.; Plachta, Nicolas; Harvey, Kieran F.
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errSave
In Vivo Imaging of Single Mammalian Cells in Development and Disease
errTrends in Molecular Medicine
IF13.8
err2018-03-01
err15
PREAI
errWhite, Melanie D.; Zhao, Ziqing W.; Plachta, Nicolas
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errSave
Quantifying transcription factor-DNA binding in single cells in vivo with photoactivatable fluorescence correlation spectroscopy
errNATURE PROTOCOLS
IF16
err2017-06-29
err19
PREAI
errZhao, Ziqing Winston; White, Melanie D.; Alvarez, Yanina D.; Zenker, Jennifer; Bissiere, Stephanie; Plachta, Nicolas
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errSave
Point mutations in murine Nkx2-5 phenocopy human congenital heart disease and induce pathogenic Wnt signaling
errJCI INSIGHT
IF6.1
err2017-03-23
err23
errOAAI
errFurtado, Milena B.; Wilmanns, Julia C.; Chandran, Anjana; Perera, Joelle; Hon, Olivia; Biben, Christine; Willow, Taylor J.; Nim, Hieu T.; Kaur, Gurpreet; Simonds, Stephanie; Wu, Qizhu; Willians, David; Salimova, Ekaterina; Plachta, Nicolas; Denegre, James M.; Murray, Stephen A.; Fatkin, Diane; Cowley, Michael; Pearson, James T.; Kaye, David; Ramialison, Mirana; Harvey, Richard P.; Rosenthal, Nadia A.; Costa, Mauro W.
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errSave
How cells change shape and position in the early mammalian embryo
errCURRENT OPINION IN CELL BIOLOGY
IF4.3
err2017-02-01
err23
PREAI
errWhite, Melanie D.; Zenker, Jennifer; Bissiere, Stephanie; Plachta, Nicolas
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
C
Carl H. June
H-index: 177 · Papers: 1.4K
L
Lewis L. Lanier
H-index: 165 · Papers: 709
J
John F. Cryan
H-index: 162 · Papers: 1.3K
C
Carlos Simón
H-index: 114 · Papers: 1.0K
A
Anthony A. Grace
H-index: 109 · Papers: 506
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