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Francis K.L. Chan

Department of Medicine and Therapeutics

128H-index
1.3KPaper Count
7.1WCitation Count
Published Papers 455
Publication Date
Clinical applications of gut microbiome for non-invasive diagnosis of colorectal neoplasia
err2026-07-30
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errOAAI
errColin Cui; Haiyun Shi; Yuji Naito; Koji Otani; Francis K. L. Chan
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Novel bacterium Enterocloster sp. M3 promotes colorectal tumorigenesis via the production of the carcinogen styrene
err2026-02-16
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errOAAI
errYao Zeng; Yao Huang; Silin Ye; Effie Yin Tung Lau; Man Chun Chiu; Linda Fenske; Yuting Sun; Liting Jiang; Jiangying Chen; Yanqing Huang; Tingyu Zhou; Jiawei Lu; Jie Zhou; Shu Zheng; Francis Ka Leung Chan; Jessie Qiaoyi Liang
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Towards global healthy longevity: report from the 1st World Longevity Summit in Kyotango, Japan
err2025-11-18
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errTomoya Kitani; Satoaki Matoba; Yuji Naito; Steve Horvath; Tamotsu Yoshimori; Francis K. L. Chan; Tomoo Matsuda; Stefania Bandini; Hironori Nakagami; Ryuichi Morishita; Yasushi Nakayama; Hitoshi Yaku
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The Mediating Role of Eating Behaviors Between Autistic Symptoms and Dietary Issues Among Chinese Children With Autism
err2025-11-17
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errYuqi Wu; Sandra S. M. Chan; Patrick W. L. Leung; Holly H. L. Lo; Stephy W. S. Ho; Flora Y. M. Mo; Carol S. W. Ho; Caroline K. S. Shea; Qi Su; Ting Fan Leung; Francis K. L. Chan; Siew Chien Ng; Oscar W. H. Wong
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Questionnaire Survey on the Current Status of Advanced Therapy for Inflammatory Bowel Disease in Asia
err2025-11-01
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PREAI
errToya, Yosuke; Shiotani, Akiko; Ono, Shoko; Saito, Yutaka; Sugimoto, Mitsushige; Naito, Yuji; Nomura, Sachiyo; Handa, Osamu; Hisamatsu, Tadakazu; Fujishiro, Mitsuhiro; Matsuda, Takahisa; Morita, Yoshinori; Yahagi, Naohisa; Chan, Francis K. L.; Ang, Tiing Leong; Abdullah, Murdani; Tablante, Maria Carla; Prachayakul, Varayu; Li, Baiwen; Jung, Hwoon-Yong; Matsumoto, Takayuki
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The Distinctive Clinical Profiles of Children With Autism Suffering From Different Subtypes of Rome IV Functional Gastrointestinal Disorders
err2025-11-01
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PREAI
errWong, Isaac Ho Wai; Ng, Sze-mai; Lam, Angela Man Wai; Chan, Sandra Sau Man; Ng, Shing-him; Leung, Jet; Lee, Keith Chun Lok; Wong, Arthur Chun Chi; Wu, Yuqi; Chan, Francis Ka Leung; Ng, Siew Chien; Wong, Oscar Wing Ho
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The resident gut microbiome modulates the effect of synbiotics on the immunogenicity after SARS-COV-2 vaccination in elderly and diabetes patients
err2025-08-25
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errOAAI
errLin Zhang; Shilan Wang; Martin C. S. Wong; Chris K. P. Mok; Jessica Y. L. Ching; Joyce W. Y. Mak; Chunke Chen; Bing Huo; Shuai Yan; Chun Pan Cheung; Emily O. L. Chiu; Emily Y. T. Fung; Pui Kuan Cheong; Francis K. L. Chan; Siew C. Ng
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The Role of Gut Microbiota in Insomnia: A Systematic Review of Case–Control Studies
err2025-08-23
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PREAI
errYun Wang; Suyi Xie; Sizhe Chen; Chenyu Li; Yeuk Lam Chan; Ngan Yin Chan; Yun Kwok Wing; Francis K. L. Chan; Qi Su; Siew C. Ng
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Gastrointestinal health and nutritional strategies in autism spectrum disorder
err2025-06-18
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errYuqi Wu; Oscar Wing Ho Wong; Sizhe Chen; Siew Chien Ng; Qi Su; Francis Ka Leung Chan
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Microbiome mismatches from microbiota transplants lead to persistent off-target metabolic and immunomodulatory effects
errCell
IF42.5
err2025-06-06
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PREAI
errOrlando DeLeon; Mora Mocanu; Alan Tan; Ashley M. Sidebottom; Jason Koval; Hugo D. Ceccato; Sarah Kralicek; John J. Colgan; Marissa M. St. George; Joash M. Lake; Michael Cooper; Jingwen Xu; Julia Moore; Qi Su; Zhilu Xu; Siew C. Ng; Francis K.L. Chan; Hein M. Tun; Candace M. Cham; Cambrian Y. Liu; David T. Rubin; Kristina Martinez-Guryn; Eugene B. Chang
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Diet outperforms microbial transplant to drive microbiome recovery in mice
errNATURE
IF48.5
err2025-04-30
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PREAI
errKennedy, M. S.; Freiburger, A.; Cooper, M.; Beilsmith, K.; George, M. L. St; Kalski, M.; Cham, C.; Guzzetta, A.; Ng, S. C.; Chan, F. K.; DeLeon, O.; Rubin, D.; Henry, C. S.; Bergelson, J.; Chang, E. B.
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Preferred Reporting Items for Microbiotherapy (PRIM) Guidelines Across Medical Disciplines: An International Delphi Consensus
err2025-03-01
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errZhang, Faming; Kamm, Michael A.; Wu, Xia; Kao, Dina; Borody, Thomas J.; Chen, Lea Ann; He, Xingxiang; Fischer, Monika; Wong, Sunny H.; Ng, Siew C.; Cui, Bota; Chan, Francis K-L; Nie, Yongzhan; Sood, Ajit; Li, Jingnan; Sun, Yang; Dai, Ishikawa; Chen, Qiyi; Lv, Muhan; Zhang, Zulun; Ianiro, Gianluca; Yang, Yunsheng; Kelly, Colleen R.
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Roseburia hominis improves host metabolism in diet-induced obesity
err2025-02-20
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errOAAI
errWenli Huang; Wenyi Zhu; Yu Lin; Francis K. L. Chan; Zhilu Xu; Siew C. Ng
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Early-life antibiotic exposure aggravates hepatic steatosis through enhanced endotoxemia and lipotoxic effects driven by gut Parabacteroides
errMEDCOMM
IF10.7
err2025-02-17
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errZhang, Xi; Chan, Darren Chak Lun; Zhu, Jie; Sin, Daniel Zhen Ye; Peng, Ye; Wong, Matthew Kwok Leong; Zhu, Wenyi; Tsui, Yee; Haqq, Andrea M.; Ting, Joseph Y.; Kozyrskyj, Anita; Chan, Francis Ka Leung; Ng, Siew Chien
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Questionnaire Survey on the Diagnosis and Treatments of Eosinophilic Gastrointestinal Diseases in Asia
err2025-02-13
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PREAI
errTsuzuki, Yoshikazu; Shiotani, Akiko; Miyaguchi, Kazuya; Ono, Shouko; Saito, Yutaka; Sugimoto, Mitsushige; Naito, Yuji; Nomura, Sachiyo; Handa, Osamu; Hisamatsu, Tadakazu; Fujishiro, Mitsuhiro; Matsuda, Takahisa; Morita, Yoshinori; Yahagi, Naohisa; Chan, Francis K. L.; Ang, Tiing Leong; Abdullah, Murdani; Tablante, Maria Carla; Prachayakul, Varayu; Li, Baiwen; Jung, Hwoon-Yong; Matsumoto, Hisashi; Shiomi, Rie; Imaeda, Hiroyuki
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Long-term use of low-dose aspirin for cancer prevention: A 20-year longitudinal cohort study of 1,506,525 Hong Kong residents
err2025-01-18
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errOAAI
errLam, Amy; Hao, Ziyu; Yiu, Karen; Chan, Stephen; Chan, Francis; Sung, Joseph; Tsoi, Kelvin
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Impacts of COVID-19 pandemic on early life gut microbiome
err2024-12-31
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errLin Zhang; Wenye Xu; Henry Y. H. Meng; Jessica Y. L. Ching; Yingzhi Liu; Shilan Wang; Shuai Yan; Ling Lin; Pui K. Cheong; Ka L. Ip; Ye Peng; Jie Zhu; Chun P. Cheung; Ting F. Leung; Agnes S. Y. Leung; Wing H. Tam; Tak Y. Leung; Paul K. S. Chan; Eugene B. Chang; David T. Rubin; Erika C. Claud; William K. K. Wu; Hein M. Tun; Francis K. L. Chan; Siew C. Ng
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The Long-Term Risk of Metachronous Advanced Adenoma Recurrence After Endoscopic Submucosal Dissection for Colorectal Neoplasia: A Propensity-Score Matched Longitudinal Cohort With 5-Year Follow-Up
err2024-12-21
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errDai, Min; Xiao, Xiang; Guo, Cosmos L. T.; Lui, Rashid N.; Yip, Hon Chi; Chu, Simon; Hon, Sok Fei; Ng, Simon S. M.; Chiu, Philip W. Y.; Ng, Siew C.; Chan, Francis K. L.; Lau, Louis H. S.
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Variation in the metagenomic analysis of fecal microbiome composition calls for a standardized operating approach
err2024-12-05
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errXu, Zhilu; Yeoh, Yun Kit; Tun, Hein M.; Fei, Na; Zhang, Jingwan; Morrison, Mark; Kamm, Michael A.; Yu, Jun; Chan, Francis Ka Leung; Ng, Siew C.
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Fecal Microbiota Transplantation for Sleep Disturbance in Post-acute COVID-19 Syndrome
err2024-12-01
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PREAI
errLau, Raphaela I.; Su, Qi; Ching, Jessica Y. L.; Lui, Rashid N.; Chan, Ting Ting; Wong, Marc T. L.; Lau, Louis H. S.; Wing, Yun Kwok; Chan, Rachel N. Y.; Kwok, Hanson Y. H.; Ho, Agnes H. Y.; Tse, Yee Kit; Cheung, Chun Pan; Li, Moses K. T.; Siu, Wan Ying; Liu, Chengyu; Lu, Wenqi; Wang, Yun; Chiu, Emily O. L.; Cheong, Pui Kuan; Chan, Francis K. L.; Ng, Siew C.
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