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Natalie Cook

Faculty of Biology

33H-index
283Paper Count
8.1KCitation Count
Published Papers 77
Publication Date
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A prospective national precision medicine trial evaluating the feasibility of blood-based molecular profiling in patients with Cancer of Unknown Primary (CUP-COMP)
errBritish Journal of Cancer
IF6.8
err2026-07-20
err0
errOAAI
errAlicia-Marie Conway; Matthew Robinson; Matthew Concannon; Sally Clive; Tania Tillett; Kai-Keen Shiu; Louise Medley; Sonali Dasgupta; Eliyaz Ahmed; Kelly Warrington; Usman Mahmood; Zoulikha Zair; Tess Gillham; Aaron Davis; Julie-Anne Scott; Alison Taylor; Mark Stares; Claire Mitchell; Pedro Oliviera; George J. Burghel; Natalie Cook
errShare
errSave
Psychological Screening and Support for Patients Enrolled in Early-Phase Cancer Clinical Trials and the Possible Barriers: A Real-World Tertiary Center Implementation Study
errPsycho-Oncology
IF3.5
err2026-04-06
err0
errOAAI
errMatthew D. Robinson; Ruiyang Yan; Amy Smith; Harriet Morley; Louise Carter; Donna Graham; Matt Krebs; Fiona Thistlethwaite; Natalie Cook
errShare
errSave
Experimental Cancer Medicine Centre (ECMC) network proposal for a consensus gene panel for pan-cancer sequencing: a Delphi methodology
errBritish Journal of Cancer
IF6.8
err2025-11-08
err0
errOAAI
errRichard Phillips; Bristi Basu; Zohra Butt; Mounia Beloueche; Natalie Cook; Simon J. Crabb; Alastair Greystoke; Darren Hargrave; Robert Jones; Muhammad Yasin Kureeman; Juanita Lopez; Claire McKeeve; Magdalena Meissner; Brent O’Carrigan; Eileen E. Parkes; Milind Ronghe; Patricia Roxburgh; Debashis Sarker; Kienan I. Savage; Paul H. S. Shaw; Stefan Symeonides; Deborah A. Tweddle; Aditi Vedi; Harriet S. Walter; Joanna Zabkiewicz; Gary W. Middleton; Andrew D. Beggs
errShare
errSave
Patient and Clinician Perspectives on the Communication of Genomic Results in Cancer Care
errCancer Medicine
IF3.1
err2025-10-09
err0
errOAAI
errEleanor Johnston; Zoulikha Zair; Leanna Goodwin; Louise Carter; Fiona Thistlethwaite; Matthew G. Krebs; Donna M. Graham; Kate Duffus; Emma Darlington; Natalie Cook
errShare
errSave
Overcoming data management challenges in oncology research: Lessons from an NHS, industry, technology start-up and academic collaboration
errEuropean Journal of Cancer
IF7.1
err2025-08-12
err0
errOAAI
errAlicia-Marie Conway; Matthew Concannon; Steven Brown; Humera Hussain; April Marland; Matthew Griffiths; Barney Plummer; Kelly Warrington; Claire Bridges; Karen Lightning-Jones; Natalie Cook
errShare
errSave
Cancer of unknown primary: the hunt for its elusive tissue-of-origin – is it time to call off the search?
errBritish Journal of Cancer
IF6.8
err2025-07-04
err0
errOAAI
errLaura Spurgeon; Claire Mitchell; Natalie Cook; Alicia-Marie Conway
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errSave
TIMEPOINT, a phase 1 study combining MTL-CEBPA with pembrolizumab, supports the immunomodulatory effect of MTL-CEBPA in solid tumors
errCELL REPORTS MEDICINE
IF10.6
err2025-04-01
err0
errOAAI
errPlummer, Ruth; Sodergren, Mikael H.; Hodgson, Rose; Ryan, Brid M.; Raulf, Nina; Nicholls, Joanna P.; Reebye, Vikash; Voutila, Jon; Sinigaglia, Laura; Meyer, Tim; Pinato, David J.; Sarker, Debashis; Basu, Bristi; Blagden, Sarah; Cook, Natalie; Evans, Thomas R. Jeffrey; Yachnin, Jeffrey; Chee, Cheng E.; Li, Daneng; El-Khoueiry, Anthony; Diab, Maria; Huang, Kai-Wen; Pai, Madhava; Spalding, Duncan; Talbot, Thomas; Noel, Marcus S.; Keenan, Bridget; Mahalingam, Devalingam; Song, Min-Sun; Grosso, Melanie; Arnaud, Denis; Auguste, Aurelie; Zacharoulis, Dimitris; Storkholm, Jan; Mcneish, Iain; Habib, Robert; Rossi, John J.; Habib, Nagy A.
errShare
errSave
Real-world experience of Molecular Tumour Boards for clinical decision-making for cancer patients
errNPJ PRECISION ONCOLOGY
IF8
err2025-03-25
err0
errOAAI
errColomina, Julio Herrero; Johnston, Eleanor; Duffus, Kate; Zair, Zoulikha M.; Thistlethwaite, Fiona; Krebs, Matthew; Carter, Louise; Graham, Donna; Cook, Natalie
errShare
errSave
Discovering an unknown risk. The unnoticed, potientially life-threatening risk to people with an inherited cardaic arrhythmia during the non-cardiac perioperative period.
errEUROPEAN HEART JOURNAL
IF35.6
err2024-10-28
err0
PREAI
errMcglinchey, L.; Barr, O.; Cook, N.
errShare
errSave
Opevesostat (MK-5684/ODM-208), an oral CYP11A1 inhibitor, in metastatic castration-resistant prostate cancer (mCRPC): Updated CYPIDES phase II results
errANNALS OF ONCOLOGY
IF65.4
err2024-09-01
err0
PREAI
errFizazi, K.; Roubaud, G.; Bernard-Tessier, A.; Gravis, G.; Flechon, A.; Ratta, R.; Barthelemy, P.; Jones, R. J.; Parikh, O. A.; Hussain, A.; van der Voet, J. C. M.; Cook, N.; Tanner, M. M. E.; Jones, R. H.; Garratt, C.; Ikonen, T.; Pohjanjousi, P.; Poehlein, C. H.; Antonarakis, E. S.
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errSave
A phase I trial of AVA6000, a fibroblast activation protein (FAP)-released, tumor microenvironment (TME)-targeted doxorubicin peptide drug conjugate in patients with FAP-positive solid tumors
errANNALS OF ONCOLOGY
IF65.4
err2024-09-01
err1
PREAI
errTwelves, C. J.; Banerji, U.; Tap, W. D.; Cook, N.; Evans, T. R. J.; Plummer, R.; Anthoney, A.; Plummer, C.; Dawson, R.; Loadman, P.; Lahu, G.; Jones, H.; Kinnersley, N.; Edwards, R.; Gordon, G.; Cranmer, L. D.
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errSave
Outcomes of patients (pts) with unfavourable, nonsquamous cancer of unknown primary (CUP) progressing after induction chemotherapy (CTX) in the global, open-label, phase II CUPISCO study
errANNALS OF ONCOLOGY
IF65.4
err2024-09-01
err0
PREAI
errBochtler, T.; Kraemer, A.; Pauli, C.; Duran-Pacheco, G.; Arslan, C.; Bigot, F.; Chalabi, N.; Cook, N.; Italiano, A.; Losa, F.; Menezes, J.; Ma, N.; Ozguroglu, M.; Pazo Cid, R. A.; Ross, J. S.; Shiu, K-K.; Arni, P.; Moch, H.; Mileshkin, L.
errShare
errSave
Short Versus Long Antibiotic Duration in Streptococcus pneumoniae Bacteremia
errOPEN FORUM INFECTIOUS DISEASES
IF3.8
err2024-08-30
err1
errOAAI
errCrotty, Matthew; Devall, Hadley; Cook, Natalie; Fischer, Francis; Alexander, Julie; Hunter, Leigh; Dominguez, Edward
errShare
errSave
Molecularly guided therapy versus chemotherapy after disease control in unfavourable cancer of unknown primary (CUPISCO): an open-label, randomised, phase 2 study
errLANCET
IF88.5
err2024-08-01
err8
PREAI
errKraemer, Alwin; Bochtler, Tilmann; Pauli, Chantal; Shiu, Kai-Keen; Cook, Natalie; de Menezes, Juliana Janoski; Pazo-Cid, Roberto A.; Losa, Ferran; Robbrecht, Debbie G. J.; Tomasek, Jiri; Arslan, Cagatay; Ozguroglu, Mustafa; Stahl, Michael; Bigot, Frederic; Kim, Sun Young; Naito, Yoichi; Italiano, Antoine; Chalabi, Nassera; Duran-Pacheco, Gonzalo; Michaud, Chantal; Scarato, Jeremy; Thomas, Marlene; Ross, Jeffrey S.; Moch, Holger; Mileshkin, Linda
errShare
errSave
Social determinants of health inequalities in early phase clinical trials in Northern England
errBRITISH JOURNAL OF CANCER
IF6.8
err2024-06-24
err1
errOAAI
errRae, S.; Shaya, S.; Taylor, E.; Hoben, J.; Oluwashegun, D.; Lowe, H.; Haris, N.; Bashir, S.; Oing, C.; Krebs, M. G.; Thistlethwaite, F. C.; Carter, L.; Cook, N.; Greystoke, A.; Graham, D. M.; Plummer, R.
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errSave
Phase II results of the porcupine (PORCN) inhibitor zamaporvint (RXC004) in genetically selected microsatellite stable colorectal cancer patients
errANNALS OF ONCOLOGY
IF65.4
err2024-06-01
err0
PREAI
errCook, N.; Bridgewater, J. A.; Saunders, M. P.; Kopetz, S.; Garcia-Carbonero, R.; Beom, S-H.; O'Neil, B. H.; Wilson, R. H.; Graham, J.; Maurel, J.; Kim, T. W.; Chau, I.; Saleha, S.; Goodwin, L.; Wilson, D.; Robertson, J.; Timmis, H.; Asken, E.; Woodcock, S. A.; Morris, V.
errShare
errSave
A cfDNA methylation-based tissue-of-origin classifier for cancers of unknown primary
errNATURE COMMUNICATIONS
IF15.7
err2024-04-17
err4
errOAAI
errConway, Alicia-Marie; Pearce, Simon P.; Clipson, Alexandra; Hill, Steven M.; Chemi, Francesca; Slane-Tan, Dan; Ferdous, Saba; Hossain, A. S. Md Mukarram; Kamieniecka, Katarzyna; White, Daniel J.; Mitchell, Claire; Kerr, Alastair; Krebs, Matthew G.; Brady, Gerard; Dive, Caroline; Cook, Natalie; Rothwell, Dominic G.
errShare
errSave
A Phase I trial of AVA6000, a Fibroblast Activation Protein (FAP)-released and tumor microenvironment (TME)-targeted doxorubicin peptide drug conjugate in patients with FAP-positive solid tumors
errCANCER RESEARCH
IF16.6
err2024-04-05
err1
PREAI
errBanerji, Udai; Cook, Natalie; Anthoney, Alan; Plummer, Ruth; Tap, William D.; Evans, Jeffry T.; Cranmer, Lee D.; Plummer, Christopher; Loadman, Paul; Lahu, Gezim; Jones, Huw S.; Kinnersley, Nelson; McLaughlin, Fiona; Twelves, Chris
errShare
errSave
Final results of the first-in-human study of the porcupine (PORCN) inhibitor zamaporvint (RXC004) in patients with advanced solid tumors
errCANCER RESEARCH
IF16.6
err2024-04-05
err0
PREAI
errCook, Natalie; Blagden, Sarah; Lopez, Juanita; Sarker, Debashis; Greystoke, Alastair; Haris, Noor Md; Kazmi, Farasat; Anam, Kaiser; Franco, Ana Ortego; Pihlak, Rille; Goodwin, Louise; Wilson, David; Phillips, Caroline; Robertson, Jane; Timmis, Helen; Tilston, Craig; Woodcock, Simon A.; Plummer, Ruth
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errSave
RNA regulatory disruption by 3′-dATP: A novel approach to inhibit ribosome biogenesis in cancer
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errElshani, Mustafa; Zhang, Ying; Um, In Hwa; Plummer, Ruth; Blagden, Sarah P.; Symeonides, Stefan N.; Cook, Natalie; Evans, T. R. Jeffry; Dickson, Alison L.; Harrison, David J.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
G
Georgina V. Long
H-index: 169 · Papers: 1.8K
A
Adi F. Gazdar
H-index: 161 · Papers: 1.2K
J
Johann S. de Bono
H-index: 160 · Papers: 2.5K
J
James Larkin
H-index: 128 · Papers: 1.3K
K
Karim Fizazi
H-index: 123 · Papers: 1.5K
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