Not logged inCone photoreceptor phosphodiesterase PDE6H inhibition regulates cancer cell growth and metabolism, replicating the dark retina response (12, 5, 2024)
Yalaz, Ceren; Bridges, Esther; Alham, Nasullah K.; Zois, Christos E.; Chen, Jianzhou; Bensaad, Karim; Miar, Ana; Pires, Elisabete; Muschel, Ruth J.; Mccullagh, James S. O.; Harris, Adrian L.
Share
Save
Share
SaveCone photoreceptor phosphodiesterase PDE6H inhibition regulates cancer cell growth and metabolism, replicating the dark retina response
Yalaz, Ceren; Bridges, Esther; Alham, Nasullah K.; Zois, Christos E.; Chen, Jianzhou; Bensaad, Karim; Miar, Ana; Pires, Elisabete; Muschel, Ruth J.; Mccullagh, James S. O.; Harris, Adrian L.
Share
SaveIonizing Radiation Drives Key Regulators of Antigen Presentation and a Global Expansion of the Immunopeptidome
Tailor, Arun; Estephan, Hala; Parker, Robert; Woodhouse, Isaac; Abdulghani, Majd; Nicastri, Annalisa; Jones, Keaton; Salatino, Silvia; Muschel, Ruth; Humphrey, Timothy; Giaccia, Amato; Ternette, Nicola
Share
Save
Share
SaveEndothelial cell death after ionizing radiation does not impair vascular structure in mouse tumor models
Kaeppler, Jakob R.; Chen, Jianzhou; Buono, Mario; Vermeer, Jenny; Kannan, Pavitra; Cheng, Wei-Chen; Voukantsis, Dimitrios; Thompson, James M.; Hill, Mark A.; Allen, Danny; Gomes, Ana; Kersemans, Veerle; Kinchesh, Paul; Smart, Sean; Buffa, Francesca; Nerlov, Claus; Muschel, Ruth J.; Markelc, Bostjan
Share
Save
Share
SaveIrradiation at Ultra-High (FLASH) Dose Rates Reduces Acute Normal Tissue Toxicity in the Mouse Gastrointestinal System
Ruan, Jia-Ling; Lee, Carl; Wouters, Shari; Tullis, Iain D. C.; Verslegers, Mieke; Mysara, Mohamed; Then, Chee Kin; Smart, Sean C.; Hill, Mark A.; Muschel, Ruth J.; Giaccia, Amato J.; Vojnovic, Borivoj; Kiltie, Anne E.; Petersson, Kristoffer
Share
SaveTumour irradiation combined with vascular-targeted photodynamic therapy enhances antitumour effects in pre-clinical prostate cancer
Sjoberg, Hanna T.; Philippou, Yiannis; Magnussen, Anette L.; Tullis, Iain D. C.; Bridges, Esther; Chatrian, Andrea; Lefebvre, Joel; Tam, Ka Ho; Murphy, Emma A.; Rittscher, Jens; Preise, Dina; Agemy, Lilach; Yechezkel, Tamar; Smart, Sean C.; Kinchesh, Paul; Gilchrist, Stuart; Allen, Danny P.; Scheiblin, David A.; Lockett, Stephen J.; Wink, David A.; Lamb, Alastair D.; Mills, Ian G.; Harris, Adrian; Muschel, Ruth J.; Vojnovic, Boris; Scherz, Avigdor; Hamdy, Freddie C.; Bryant, Richard J.
Share
Save
Share
SaveLiver metastases
Tsilimigras, Diamantis I.; Brodt, Pnina; Clavien, Pierre-Alain; Muschel, Ruth J.; D'Angelica, Michael I.; Endo, Itaru; Parks, Rowan W.; Doyle, Majella; de Santibanes, Eduardo; Pawlik, Timothy M.
Share
SaveDeletion of the deISGylating enzyme USP18 enhances tumour cell antigenicity and radiosensitivity
Pinto-Fernandez, Adan; Salio, Mariolina; Partridge, Tom; Chen, Jianzhou; Vere, George; Greenwood, Helene; Olie, Cyriel Sebastiaan; Damianou, Andreas; Scott, Hannah Claire; Pegg, Henry Jack; Chiarenza, Alessandra; Diaz-Saez, Laura; Smith, Paul; Gonzalez-Lopez, Claudia; Patel, Bhavisha; Anderton, Emma; Jones, Neil; Hammonds, Tim R.; Huber, Kilian; Muschel, Ruth; Borrow, Persephone; Cerundolo, Vincenzo; Kessler, Benedikt M.
Share
SaveAbnormal morphology biases hematocrit distribution in tumor vasculature and contributes to heterogeneity in tissue oxygenation
Bernabeu, Miguel O.; Kory, Jakub; Grogan, James A.; Markelc, Bostjan; Beardo, Albert; d'Avezac, Mayeul; Enjalbert, Romain; Kaeppler, Jakob; Daly, Nicholas; Hetherington, James; Kruger, Timm; Maini, Philip K.; Pitt-Francis, Joe M.; Muschel, Ruth J.; Alarcon, Tomas; Byrne, Helen M.
Share
Save
Share
SaveUSP18 modulates the ISGylome, immune signaling and sensitizes tumor cells to irradiation and CTL recognition
Pinto-Fernandez, Adan; Greenwood, Helene; Salio, Mariolina; Chen, Jianzhou; Partridge, Thomas; Vere, George; Scott, Hannah C.; Damianou, Andreas; Borrow, Persephone; Muschel, Ruth; Cerundolo, Vincenzo; Kessler, Benedikt M.
Share
SaveFGF2 alters macrophage polarization, tumour immunity and growth and can be targeted during radiotherapy
Im, Jae Hong; Buzzelli, Jon N.; Jones, Keaton; Franchini, Fanny; Gordon-Weeks, Alex; Markelc, Bostjan; Chen, Jianzhou; Kim, Jin; Cao, Yunhong; Muschel, Ruth J.
Share
Save
Share
SaveImpacts of combining anti-PD-L1 immunotherapy and radiotherapy on the tumour immune microenvironment in a murine prostate cancer model
Philippou, Yiannis; Sjoberg, Hanna T.; Murphy, Emma; Alyacoubi, Said; Jones, Keaton I.; Gordon-Weeks, Alex N.; Phyu, Su; Parkes, Eileen E.; Gillies McKenna, W.; Lamb, Alastair D.; Gileadi, Uzi; Cerundolo, Vincenzo; Scheiblin, David A.; Lockett, Stephen J.; Wink, David A.; Mills, Ian G.; Hamdy, Freddie C.; Muschel, Ruth J.; Bryant, Richard J.
Share
Save
Share
Save
Share
Save