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J

Jan Löwe

MRC Laboratory of Molecular Biology

76H-index
275Paper Count
2.2WCitation Count
Published Papers 80
Publication Date
Eukaryotic-like microtubules and dynamic instability of Asgard archaeal tubulins
err2026-07-23
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errJan Löwe; Andriko von Kügelgen; Vicente J. Planelles-Herrero; Martin B. L. McAndrew; María A. Oliva; Julian Vosseberg; Stephan Köstlbacher; Jennah E. Dharamshi; Kathryn E. Appler; Fraser I. MacLeod; Stephanie-Jane Nobs; Steffen L. Jørgensen; Brendan P. Burns; Brett J. Baker; Tanmay A. M. Bharat; Emmanuel Derivery; Daniel Tamarit; Thijs J. G. Ettema
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Mechanism of DNA capture by the MukBEF SMC complex and its inhibition by a viral DNA mimic
errCELL
IF42.5
err2025-05-01
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errOAAI
errBumann, Frank; Clifton, Bryony; Koekemoer, Sophie; Wilkinson, Oliver J.; Kimanius, Dari; Dillingnam, Mark S.; Lowe, Jan
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What AlphaFold tells us about cohesin's retention on and release from chromosomes
err2023-11-17
err6
errOAAI
errNasmyth, Kim A.; Lee, Byung-Gil; Roig, Maurici Brunet; Lowe, Jan
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Diverse cytomotive actins and tubulins share a polymerization switch mechanism conferring robust dynamics
err2023-03-31
err9
errOAAI
errWagstaff, James Mark; Planelles-Herrero, Vicente Jose; Sharov, Grigory; Alnami, Aisha; Kozielski, Frank; Derivery, Emmanuel; Lowe, Jan
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The patterned assembly and stepwise Vps4-mediated disassembly of composite ESCRT-III polymers drives archaeal cell division
err2023-03-17
err8
errOAAI
errHurtig, Fredrik; Burgers, Thomas C. Q.; Cezanne, Alice; Jiang, Xiuyun; Mol, Frank N.; Traparic, Jovan; Pulschen, Andre Arashiro; Nierhaus, Tim; Tarrason-Risa, Gabriel; Harker-Kirschneck, Lena; Lowe, Jan; Saric, Andela; Vlijm, Rifka; Baum, Buzz
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Asgard archaea shed light on the evolutionary origins of the eukaryotic ubiquitin-ESCRT machinery
err2022-06-13
err26
errOAAI
errHatano, Tomoyuki; Palani, Saravanan; Papatziamou, Dimitra; Salzer, Ralf; Souza, Diorge P.; Tamarit, Daniel; Makwana, Mehul; Potter, Antonia; Haig, Alexandra; Xu, Wenjue; Townsend, David; Rochester, David; Bellini, Dom; Hussain, Hamdi M. A.; Ettema, Thijs J. G.; Lowe, Jan; Baum, Buzz; Robinson, Nicholas P.; Balasubramanian, Mohan
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Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites
err2021-12-01
err38
errOAAI
errBurmann, Frank; Funke, Louise F. H.; Chin, Jason W.; Lowe, Jan
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Folding of cohesin's coiled coil is important for Scc2/4-induced association with chromosomes
err2021-07-14
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errPetela, Naomi J.; Llamazares, Andres Gonzalez; Dixon, Sarah; Hu, Bin; Lee, Byung-Gil; Metson, Jean; Seo, Heekyo; Ferrer-Harding, Antonio; Voulgaris, Menelaos; Gligoris, Thomas; Collier, James; Oh, Byung-Ha; Lowe, Jan; Nasmyth, Kim A.
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Structure of the SARS-CoV-2 RNA-dependent RNA polymerase in the presence of favipiravir-RTP
err2021-02-01
err140
errOAAI
errNaydenova, Katerina; Muir, Kyle W.; Wu, Long-Fei; Zhang, Ziguo; Coscia, Francesca; Peet, Mathew J.; Castro-Hartmann, Pablo; Qian, Pu; Sader, Kasim; Dent, Kyle; Kimanius, Dari; Sutherland, John D.; Lowe, Jan; Barford, David; Russo, Christopher J.
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Transport of DNA within cohesin involves clamping on top of engaged heads by Scc2 and entrapment within the ring by Scc3
err2020-09-15
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errCollier, James E.; Lee, Byung-Gil; Roig, Maurici Brunet; Yatskevich, Stanislav; Petela, Naomi J.; Metson, Jean; Voulgaris, Menelaos; Llamazares, Andres Gonzalez; Lowe, Jan; Nasmyth, Kim A.
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Identifying proteins bound to native mitotic ESC chromosomes reveals chromatin repressors are important for compaction
err2020-08-17
err21
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errDjeghloul, Dounia; Patel, Bhavik; Kramer, Holger; Dimond, Andrew; Whilding, Chad; Brown, Karen; Kohler, Anne-Celine; Feytout, Amelie; Veland, Nicolas; Elliott, James; Bharat, Tanmay A. M.; Tarafder, Abul K.; Lowe, Jan; Ng, Bee L.; Guo, Ya; Guy, Jacky; Huseyin, Miles K.; Klose, Robert J.; Merkenschlager, Matthias; Fisher, Amanda G.
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Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism
err2020-07-13
err65
errOAAI
errLee, Byung-Gil; Merkel, Fabian; Allegretti, Matteo; Hassler, Markus; Cawood, Christopher; Lecomte, Lea; O'Reilly, Francis J.; Sinn, Ludwig R.; Gutierrez-Escribano, Pilar; Kschonsak, Marc; Bravo, Sol; Nakane, Takanori; Rappsilber, Juri; Aragon, Luis; Beck, Martin; Loewe, Jan; Haering, Christian H.
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A folded conformation of MukBEF and cohesin
err2019-03-04
err91
errOAAI
errBurmann, Frank; Lee, Byung-Gil; Than, Thane; Sinn, Ludwig; O'Reilly, Francis J.; Yatskevich, Stanislau; Rappsilber, Juri; Hu, Bin; Nasmyth, Kim; Lowe, Jan
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