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T Cell-Specific Inactivation of the PI3K p110α Catalytic Subunit: Effect in T Cell Differentiation and Antigen-Specific Responses Briones, Alejandro C.; del Estal, Laura; Villa-Gomez, Cristina; Bermejo, Veronica; Cervera, Isabel; Gutierrez-Huerta, Pedro; Montes-Casado, Maria; Ortega, Sagrario; Barbacid, Mariano; Rojo, Jose Maria; Portoles, Pilar Share Save
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Type I interferon signaling pathway enhances immune- checkpoint inhibition in KRAS mutant lung tumors Fernandez-Garcia, Fernando; Fernandez-Rodriguez, Ana; Fustero-Torre, Coral; Pineiro-Yanez, Elena; Wang, Haiyun; Lechuga, Carmen G.; Callejas, Sergio; Alvarez, Rebeca; Lopez-Garcia, Alejandra; Esteban-Burgos, Laura; Salmon, Marina; San Roman, Marta; Guerra, Carmen; Ambrogio, Chiara; Drosten, Matthias; Santamaria, David; Al Shahrour, Fatima; Dopazo, Ana; Barbacid, Mariano; Musteanu, Monica Share Save
Enabling biomarkers of chromosomal instability for tumor only targeted gene panel sequencing Gomez-Sanchez, David; Thompson, Joe Sneath; Hernando, Barbara; Garcia-Lopez, Diego; de Galard, Hector; Roy, Abhipsa; Cullen, Amy; Madrid, Laura; Teles, Jose; Piskorz, Ania; Yip, Jason; Cadiz, Alice; Escobar-Rey, Maria; Moreno-Vellisca, Roberto; Carrizo, Nuria; Alvarez, Eva; Quintela-Fandino, Miguel; Barbacid, Mariano; Ramos-Paradas, Javier; Coya, Juan Manuel; Ferrer, Irene; Zugazagoitia, Jon; Paz-Ares, Luis; MacIntyre, Geoff Share Save
Signature-driven repurposing of Midostaurin for combination with MEK1/2 and KRASG12C inhibitors in lung cancer Macaya, Irati; Roman, Marta; Welch, Connor; Entrialgo-Cadierno, Rodrigo; Salmon, Marina; Santos, Alba; Feliu, Iker; Kovalski, Joanna; Lopez, Ines; Rodriguez-Remirez, Maria; Palomino-Echeverria, Sara; Lonfgren, Shane M.; Ferrero, Macarena; Calabuig, Silvia; Ludwig, Iziar A.; Lara-Astiaso, David; Jantus-Lewintre, Eloisa; Guruceaga, Elizabeth; Narayanan, Shruthi; Ponz-Sarvise, Mariano; Pineda-Lucena, Antonio; Lecanda, Fernando; Ruggero, Davide; Khatri, Purvesh; Santamaria, Enrique; Fernandez-Irigoyen, Joaquin; Ferrer, Irene; Paz-Ares, Luis; Drosten, Matthias; Barbacid, Mariano; Gil-Bazo, Ignacio; Vicent, Silve Share Save
A tumor-promoting senescent secretome triggered by platinum chemotherapy exploits a targetable TGFβR1/Akt-mTOR axis in lung cancer Gonzalez-Gualda, Estela; Macias, David; Morsli, Samir; Martin, Jose Ezequiel; Ou, Hui-Ling; Denholm, Mary; Olan, Ioana; Hoffmann, Reuben; Dane, Mark; Veroutis, Dimitris; Medrano, Guillermo; Mulero, Francisca; Martins, Carla P.; Barbacid, Mariano; Gorgoulis, Vassilis; Korkola, James E.; Rassl, Doris M.; Doherty, Gary J.; Rintoul, Robert C.; Narita, Masashi; Munoz-Espin, Daniel Share Save
Kras oncogene ablation prevents resistance in advanced lung adenocarcinomas Salmon, Marina; Alvarez-Diaz, Ruth; Fustero-Torre, Coral; Brehey, Oksana; Lechuga, Carmen G.; Sanclemente, Manuel; Fernandez-Garcia, Fernando; Lopez-Garcia, Alejandra; Martin-Guijarro, Maria Carmen; Rodriguez-Perales, Sandra; Bousquet-Mur, Emily; Morales-Cacho, Lucia; Mulero, Francisca; Al-Shahrour, Fatima; Martinez, Lola; Dominguez, Orlando; Caleiras, Eduardo; Ortega, Sagrario; Guerra, Carmen; Musteanu, Monica; Drosten, Matthias; Barbacid, Mariano Share Save
Control of spermatogenesis in mice by the cyclin D-dependent kinase inhibitors p18Ink4c and p19Ink4d Zindy, F; den Besten, W; Chen, B; Rehg, JE; Latres, E; Barbacid, M; Pollard, JW; Sherr, CJ; Cohen, PE; Roussel, MF Share Save
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Exploiting the intrinsic misfolding propensity of the KRAS oncoprotein Janssen, Kobe; Claes, Filip; Van de Velde, Dido; Wehbi, Vanessa L.; Houben, Bert; Lampi, Yulia; Nys, Mieke; Khodaparast, Laleh; Khodaparast, Ladan; Louros, Nikolaos; van der Kant, Rob; Verniers, Joffre; Garcia, Teresa; Ramakers, Meine; Konstantoulea, Katerina; Maragkou, Katerina; Duran-Romana, Ramon; Musteanu, Monica; Barbacid, Mariano; Scorneaux, Bernard; Beirnaert, Els; Schymkowitz, Joost; Rousseau, Frederic Share Save
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Structure of the RAF1-HSP90-CDC37 complex reveals the basis of RAF1 regulation Garcia-Alonso, Sara; Mesa, Pablo; de la Puente Ovejero, Laura; Aizpurua, Gonzalo; Lechuga, Carmen G.; Zarzuela, Eduardo; Santiveri, Clara M.; Sanclemente, Manuel; Munoz, Javier; Musteanu, Monica; Campos-Olivas, Ramon; Martinez-Torrecuadrada, Jorge; Barbacid, Mariano; Montoya, Guillermo Share Save
KSR induces RAS-independent MAPK pathway activation and modulates the efficacy of KRAS inhibitors Paniagua, Guillem; Jacob, Harrys K. C.; Brehey, Oksana; Garcia-Alonso, Sara; Lechuga, Carmen G.; Pons, Tirso; Musteanu, Monica; Guerra, Carmen; Drosten, Matthias; Barbacid, Mariano Share Save
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