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S

Shom Goel

Peter MacCallum Cancer Centre

34H-index
214Paper Count
9.9KCitation Count
Published Papers 62
Publication Date
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Rb-driven transcription limits its tumour-suppressive effects in breast cancer
errNature
IF48.5
err2026-08-12
err0
errOAAI
errApril C. Watt; Antonio Ahn; Catherine Blyth; Julia R. Dixon-Douglas; Krutika Ambani; Rhiannon Coulson; Michael Taylor; Keefe T. Chan; Catherine Dietrich; Brendan E. Russ; Susanne Ramm; Christabella A. Mahendra; Kun-Hui Lu; Nichelle Pires; Jesus Garcia-Sannicolas; Olivia Voulgaris; Sheena Nunag; Ching-Seng Ang; Mark A. Dawson; Elgene Lim; Monica Arnedos; Sarat Chandarlapaty; Fabrice André; Shom Goel
errShare
errSave
Intracellular zinc protects tumours from T cell-mediated cytotoxicity
errCELL DEATH AND DIFFERENTIATION
IF15.4
err2024-09-11
err0
errOAAI
errLelliott, Emily J.; Naddaf, Jonathan; Ganio, Katherine; Michie, Jessica; Wang, Shelly; Liu, Lin; Silke, Natasha; Ahn, Antonio; Ramsbottom, Kelly M.; Brennan, Amelia J.; Freeman, Andrew J.; Goel, Shom; Vervoort, Stephin J.; Kearney, Conor J.; Beavis, Paul A.; Mcdevitt, Christopher A.; Silke, John; Oliaro, Jane
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errSave
The NEOLETRIB trial: neoadjuvant treatment with Letrozole and Ribociclib in ER-positive, HER2-negative breast cancer
errFUTURE ONCOLOGY
IF2.6
err2024-07-29
err0
errOAAI
errFjermeros, Kamilla; Ghannoum, Salim; Geisler, Stephanie B.; Bhargava, Sameer; Tahiri, Andliena; Klajic, Jovana; Luders, Torben; Fongard, Marie; Nawaz, Meh Sameen; Bosnjak-Olsen, Tatjana; Buvarp, Unn-Cathrin Edvardsen; Johanna Rosenskiold, Aino Katri; Nguyen, Nam Thi; Sletbak, Tone Tysko; Seyedzadeh, Manouchehr; Selsas, Knut; Porojnicu, Alina Carmen; Skjerven, Helle Kristine; Hovda, Tone; Sahlberg, Kristine Kleivi; Torland, Lilly Anne; Lyngra, Marianne; Hammarstrom, Clara Louise; Honigsperger, Elma Bahonjic; Noone, John Christopher; Mathiassen, Silje; Hurtado, Antoni; Goel, Shom; Koff, Andrew; Tekpli, Xavier; Kristensen, Vessela N.; Geisler, Juergen
errShare
errSave
The CD8+T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects
errIMMUNITY
IF26.3
err2024-06-01
err2
PREAI
errVan Der Byl, Willem; Nussing, Simone; Peters, Timothy J.; Ahn, Antonio; Li, Hanjie; Ledergor, Guy; David, Eyal; Koh, Andrew S.; Wagle, Mayura V.; Deguit, Christian Deo T.; de Menezes, Maria N.; Travers, Avraham; Sampurno, Shienny; Ramsbottom, Kelly M.; Li, Rui; Kallies, Axel; Beavis, Paul A.; Jungmann, Ralf; Bastings, Maartje M. C.; Belz, Gabrielle T.; Goel, Shom; Trapani, Joseph A.; Crabtree, Gerald R.; Chang, Howard Y.; Amit, Ido; Goodnow, Chris C.; Luciani, Fabio; Parish, Ian A.
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errSave
A phase 2 study of abemaciclib monotherapy for patients with retinoblastoma-positive (Rb plus ), triplenegative metastatic breast cancer
errCANCER RESEARCH
IF16.6
err2024-05-02
err0
PREAI
errGoel, Shom; Jovanovic, Bojana; Chu, Xiangying; Hughes, Melissa; Mohammed-Abreu, Ayesha; Kasparian, Julie; Erick, Timothy; DiLullo, Molly; Wrabel, Eileen; Jeselsohn, Rinath; Tayob, Nabihah; Schnitt, Stuart; Lin, Nancy; Tolaney, Sara
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errSave
AVIATOR/ TBCRC045: A randomized phase II study of vinorelbine (N) plus trastuzumab (H) alone or combined with avelumab (A) plus /- utomilumab (U) in patients (pts) with HER2+metastatic breast cancer (MBC) (NCT03414658)
errCANCER RESEARCH
IF16.6
err2024-05-02
err0
PREAI
errWaks, Adrienne; Shi, Ruichao; Regan, Meredith; Dang, Chau; Santa-Maria, Cesar; Westbrook, Kelly; Abramson, Vandana; Murthy, Rashmi; Nanda, Rita; Rugo, Hope; Clark, Amy; Mainor, Candace; Dees, Claire; Hoyos, Valentina; Miller, Kathy; Stringer-Reasor, Erica; Hunter, Natasha; Oh, Sun Young; Demeo, Michelle; Okpoebo, Amanda; Elias, Erin; Kurt, Busem; Lin, Nancy; Rimawi, Mothaffar; Wolff, Antonio; Mittendorf, Elizabeth; Goel, Shom; Tolaney, Sara; Loi, Sherene; Krop, Ian
errShare
errSave
Patients with metastatic triple-negative breast cancer who receive trilaciclib prior to cytotoxic chemotherapy exhibit improved survival after receiving subsequent anticancer therapy
errCANCER RESEARCH
IF16.6
err2024-05-02
err0
PREAI
errGoel, Shom; O'Shaughnessy, Joyce; Lu, Kun-Hui; Beelen, Andrew; Melemed, Symantha; Yi, John; Danso, Michael; Tan, Antoinette
errShare
errSave
p53 loss enables HR plus breast cancer escape from CDK4/6 inhibitorinduced quiescence via CDK2
errCANCER RESEARCH
IF16.6
err2024-05-02
err0
PREAI
errKudo, Rei; Safonov, Anton; da Silva, Edaise M.; Li, Qing; Shao, Hong; Will, Marie; Nakshatri, Harikrishna; Reis-Filho, Jorge; Goel, Shom; Koff, Andrew; Weigelt, Britta; Khan, Qamar; Razavi, Pedram; Chandarlapaty, Sarat
errShare
errSave
Regulation of Exhausted CD8+ T cell Differentiation by IKZF Transcription Factors
errCANCER RESEARCH
IF16.6
err2024-04-15
err0
PREAI
errReading, Sinead M.; Munoz, Isabelle; de Menezes, Maria N.; Saw, Nicole Y. L.; Ambani, Krutika; Ahn, Antonio; Nussing, Simone; Roth, Sara; Sampurno, Shienny; Ramsbottom, Kelly M.; Trapani, Joseph A.; Good-Jacobson, Kim L.; Johnstone, Ricky W.; Goel, Shom; Beavis, Paul A.; Parish, Ian A.
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errSave
INX-315, a Selective CDK2 Inhibitor, Induces Cell Cycle Arrest and Senescence in Solid Tumors
errCANCER DISCOVERY
IF33.3
err2023-12-01
err16
errOAAI
errDietrich, Catherine; Trub, Alec; Ahn, Antonio; Taylor, Michael; Ambani, Krutika; Chan, Keefe T.; Lu, Kun-Hui; Mahendra, Christabella A.; Blyth, Catherine; Coulson, Rhiannon; Ramm, Susanne; Watt, April C.; Matsa, Sunil Kumar; Bisi, John; Strum, Jay; Roberts, Patrick; Goel, Shom
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errSave
Overall Survival and Exploratory Biomarker Analyses of Abemaciclib plus Trastuzumab with or without Fulvestrant versus Trastuzumab plus Chemotherapy in HR+, HER2+Metastatic Breast Cancer Patients
errCLINICAL CANCER RESEARCH
IF10.2
err2023-10-31
err2
errOAAI
errTolaney, Sara M.; Goel, Shom; Nadal, Jorge; Denys, Hannelore; Borrego, Manuel R.; Litchfield, Lacey M.; Liu, Jiangang; Appiah, Adams K.; Chen, Yanyun; Andre, Fabrice
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errSave
Abemaciclib plus trastuzumab with or without fulvestrant versus trastuzumab plus standard-of-care chemotherapy in women with HR+, HER2+advanced breast cancer: plain language summary of the monarcHER study
errFUTURE ONCOLOGY
IF2.6
err2023-10-03
err1
errOAAI
errTolaney, Sara M.; Goel, Shom; Appiah, Adams Kusi; Huynh, Trish; Chen, Yanyun; Andre, Fabrice
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errSave
PD-1 blockade and CDK4/6 inhibition augment nonoverlapping features of T cell activation in cancer (vol 220, e20220729, 2023)
errJOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
err2023-08-24
err0
errOAAI
errAli, Lestat R.; Garrido-Castro, Ana C.; Lenehan, Patrick J.; Bollenrucher, Naima; Stump, Courtney T.; Dougan, Michael; Goel, Shom; Shapiro, Geoffrey I.; Tolaney, Sara M.; Dougan, Stephanie K.
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errSave
INX-315, a potent and selective CDK2 inhibitor, demonstrates robust antitumor activity in CCNE1-amplified cancers
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errTrub, Alec G.; Bisi, John E.; Dietrich, Catherine; Taylor, Michael; Strum, Jay C.; Goel, Shom; Roberts, Patrick J.
errShare
errSave
Trilaciclib induces immune changes within the tumor microenvironment in early-stage triple-negative breast cancer
errCANCER RESEARCH
IF16.6
err2023-03-01
err0
PREAI
errDanso, Michael; O'Shaughnessy, Joyce; Wang, Lisa S.; Mosalpuria, Kailash; Hurvitz, Sara; Goel, Shom; Ahn, Sarah; Cao, Subing; Yi, John S.; Oyekunle, Taofik; Jacobson, Amanda; Beelen, Andrew; Force, Jeremy
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errSave
Clinical outcomes of patients with HR+HER2-advanced breast cancer with early progression on CDK4/6 inhibitors
errCANCER RESEARCH
IF16.6
err2023-03-01
err1
PREAI
errClifton, Katherine K.; Thomas, Shana N.; Luo, Jingqin; Xi, Jing; Bagegni, Nusayba A.; Ademuyiwa, Foluso O.; Suresh, Rama; Frith, Ashley; Davis, Andrew A.; Bose, Ron; Weilbaecher, Katherine; Hensing, Whitney L.; Pluard, Timothy; Cristofanilli, Massimo; Han, Hyo S.; Brufsky, Adam M.; Kalinsky, Kevin; Goel, Shom; Wander, Seth A.; Peterson, Lindsay L.; Ma, Cynthia
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errSave
PD-1 blockade and CDK4/6 inhibition augment nonoverlapping features of T cell activation in cancer
errJOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
err2023-01-23
err14
errOAAI
errAli, Lestat R.; Garrido-Castro, Ana C.; Lenehan, Patrick J.; Bollenrucher, Naima; Stump, Courtney T.; Dougan, Michael; Goel, Shom; Shapiro, Geoffrey I.; Tolaney, Sara M.; Dougan, Stephanie K.
errShare
errSave
Emerging Therapies for Breast Cancer
errCOLD SPRING HARBOR PERSPECTIVES IN MEDICINE
IF10.1
err2022-12-12
err7
errOAAI
errGoel, Shom; Chandarlapaty, Sarat
errShare
errSave
TRANSIENT INHIBITION OF CYCLIN-DEPENDENT KINASE 4/6 WITH TRILACICLIB ENHANCES INHIBITORY RECEPTOR IMMUNOTHERAPY TO IMPROVE ANTITUMOR EFFICACY
errJOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
err2022-11-07
err0
errOAAI
errLu, Kun-Hui; Dietrich, Catherine; Ahn, Sarah; Cao, Subing; Yi, John; Goel, Shom
errShare
errSave
Trilaciclib prior to gemcitabine plus carboplatin for metastatic triple-negative breast cancer: phase III PRESERVE 2
errFUTURE ONCOLOGY
IF2.6
err2022-09-22
err12
errOAAI
errGoel, Shom; Tan, Antoinette R.; Rugo, Hope S.; Aftimos, Philippe; Andric, Zoran; Beelen, Andrew; Zhang, Jingshan; Yi, John S.; Malik, Rajesh; O'Shaughnessy, Joyce
errShare
errSave

Research Directions

No research directions
Co-authors
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