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Glycation-lowering compounds inhibit ghrelin signaling to reduce food intake, lower insulin resistance, and extend lifespan Wimer, Lauren A.; Kaneshiro, Kiyomi R.; Ramirez, Jessica; Bose, Neelanjan; Valdearcos, Martin; Shanmugam, Muniesh Muthaiyan; Farrera, Dominique O.; Singh, Parminder; Beck, Jennifer; Sellegounder, Durai; Najera, Lizbeth Enqriquez; Melov, Simon; Ellerby, Lisa M.; Cho, Soo-Jin; Newman, John C.; Koliwad, Suneil; Galligan, James J.; Kapahi, Pankaj Share Save
Cellular Senescence Mediates Doxorubicin Chemotherapy-Induced Aortic Stiffening: Role of Glycation Stress Venkatasubramanian, Ravinandan; Darrah, Mary A.; Mahoney, Sophia A.; Hutton, David A.; Maurer, Grace S.; Ludwig, Katelyn R.; Van Dongen, Nicholas S.; Greenberg, Nathan T.; Longtine, Abigail G.; Brunt, Vienna E.; Singh, Parminder; Galligan, James J.; Trujillo, Marissa N.; Kapahi, Pankaj; Melov, Simon; Rossman, Matthew J.; Seals, Douglas R.; Clayton, Zachary S. Share Save
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Glycation metabolites predict incident age-related comorbidities and mortality in older people with HIV Qiao, Xi; Zhang, Liangliang; Hoffman, Emely A.; Mastin, Grace E.; Hileman, Corrilynn O.; Kallianpur, Asha R.; Wang, Ming; Ellis, Ronald J.; Koletar, Susan L.; Palella, Frank J.; Tassiopoulos, Katherine K.; Landay, Alan L.; Kapahi, Pankaj; Galligan, James J.; Kalayjian, Robert C. Share Save
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OXR1 maintains the retromer to delay brain aging under dietary restriction Wilson, Kenneth A.; Bar, Sudipta; Dammer, Eric B.; Carrera, Enrique M.; Hodge, Brian A.; Hilsabeck, Tyler A. U.; Bons, Joanna; Brownridge, George W.; Beck, Jennifer N.; Rose, Jacob; Granath-Panelo, Melia; Nelson, Christopher S.; Qi, Grace; Gerencser, Akos A.; Lan, Jianfeng; Afenjar, Alexandra; Chawla, Geetanjali; Brem, Rachel B.; Campeau, Philippe M.; Bellen, Hugo J.; Schilling, Birgit; Seyfried, Nicholas T.; Ellerby, Lisa M.; Kapahi, Pankaj Share Save
Methylglyoxal-derived hydroimidazolone, MG-H1, increases food intake by altering tyramine signaling via the GATA transcription factor ELT-3 in Caenorhabditis elegans Shanmugam, Muniesh Muthaiyan; Chaudhuri, Jyotiska; Sellegounder, Durai; Sahu, Amit Kumar; Guha, Sanjib; Chamoli, Manish; Hodge, Brian; Bose, Neelanjan; Roberts, Charis; Farrera, Dominique O.; Lithgow, Gordon; Sarpong, Richmond; Galligan, James J.; Kapahi, Pankaj Share Save
Longitudinal fundus imaging and its genome-wide association analysis provide evidence for a human retinal aging clock Ahadi, Sara; Wilson, Kenneth A.; Babenko, Boris; McLean, Cory Y.; Bryant, Drew; Pritchard, Orion; Kumar, Ajay; Carrera, Enrique M.; Lamy, Ricardo; Stewart, Jay M.; Varadarajan, Avinash; Berndl, Marc; Kapahi, Pankaj; Bashir, Ali Share Save
NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health Lee, Patty J.; Benz, Christopher C.; Blood, Philip; Boerner, Katy; Campisi, Judith; Chen, Feng; Daldrup-Link, Heike; De Jager, Phil; Ding, Li; Duncan, Francesca E.; Eickelberg, Oliver; Fan, Rong; Finkel, Toren; Furman, David; Garovic, Vesna; Gehlenborg, Nils; Glass, Carolyn; Heckenbach, Indra; Joseph, Ziv-Bar; Katiyar, Pragati; Kim, So-Jin; Koenigshoff, Melanie; Kuchel, George A.; Lee, Haesung; Lee, Jun Hee; Ma, Jian; Ma, Qin; Melov, Simon; Metis, Kay; Mora, Ana L.; Musi, Nicolas; Neretti, Nicola; Passos, Joao F.; Rahman, Irfan; Rivera-Mulia, Juan Carlos; Robson, Paul; Rojas, Mauricio; Roy, Ananda L.; Scheibye-Knudsen, Morten; Schilling, Birgit; Shi, Pixu; Silverstein, Jonathan C.; Suryadevara, Vidyani; Xie, Jichun; Wang, Jinhua; Wong, A. Ian; Niedernhofer, Laura J.; Wang, Siyuan (Steven); Anvari, Hannah; Balough, Julia; Benz, Christopher; Bons, Joanna; Brenerman, Boris; Evans, William; Gerencser, Akos; Gregory, Heather; Hansen, Malene; Justice, Jamie; Kapahi, Pankaj; Murad, Natalia; O'Broin, Amy; Pavone, Mary Ellen; Powell, Mark; Scott, Gary; Shanes, Elisheva; Shankaran, Mahalakshmi; Verdin, Eric; Winer, Daniel; Wu, Fei; Adams, Andrew; Blood, Philip D.; Bueckle, Andreas; Cao-Berg, Ivan; Chen, Hao; Davis, Michael; Filus, Shane; Hao, Yuhan; Hartman, Austin; Hasanaj, Euxhen; Helfer, Jesse; Herr, Bruce, II; Bar Joseph, Ziv; Molla, Gesmira; Mou, Gloria; Puerto, Juan; Quardokus, Ellen M.; Ropelewski, Alexander J.; Ruffalo, Matt; Satija, Rahul; Schwenk, Melissa; Scibek, Robin; Shirey, William; Sibilla, Max; Welling, Joel; Yuan, Zhou; Bonneau, Richard; Christiano, Angela; Izar, Benjamin; Menon, Vilas; Owens, David M.; Phatnani, Hemali; Smith, Colin; Suh, Yousin; Teich, Andrew F.; Bekker, Valerie; Chan, Cliburn; Coutavas, Elias; Hartwig, Matthew G.; Ji, Zhicheng; Nixon, Andrew B.; Dou, Zhixun; Rajagopal, Jayaraj; Slavov, Nikolai; Holmes, David, III; Jurk, Diana; Kirkland, James L.; Lagnado, Anthony; Tchkonia, Tamara; Abraham, Kristin; Dibattista, Amanda; Fridell, Yih-Woei; Howcroft, T. Kevin; Jhappan, Chamelli; Montes, Viviana Perez; Prabhudas, Mercy; Resat, Haluk; Taylor, Veronica; Kumar, Manoj; Cigarroa, Francisco; Cohn, Rachel; Cortes, Tiffany M.; Courtois, Elise; Chuang, Jeffrey; Dave, Monica; Domanskyi, Sergii; Enninga, Elizabeth Ann Lieser; Eryilmaz, Giray Naim; Espinoza, Sara E.; Gelfond, Jon; Kirkland, James; Kuo, Chia-Ling; Lehman, Julia S.; Aguayo-Mazzucato, Cristina; Meves, Alexander; Rani, Meenakshi; Sanders, Shane; Thibodeau, Asa; Tullius, Stefan G.; Ucar, Duygu; White, Brian; Wu, Qian; Xu, Ming; Yamaguchi, Seiji; Assarzadegan, Naziheh; Cho, Chun-Seok; Hwang, Irene; Hwang, Yongha; Xi, Jingyue; Adeyi, Oyedele A.; Aliferis, Constantin F.; Bartolomucci, Alessandro; Dong, Xiao; DuFresne-To, Mickayla J.; Ikramuddin, Sayeed; Johnson, Steve G.; Nelson, Andrew C.; Revelo, Xavier S.; Trevilla-Garcia, Claudia; Sedivy, John M.; Thompson, Elizabeth L.; Robbins, Paul D.; Wang, Jinhua; Aird, Katherine M.; Alder, Jonathan K.; Beaulieu, Delphine; Bueno, Marta; Calyeca, Jazmin; Chamucero-Millaris, Julian A.; Chan, Stephen Y.; Chung, Dongjun; Corbett, Anthony; Gorbunova, Vera; Gowdy, Kymberly M.; Gurkar, Aditi; Horowitz, Jeffrey C.; Hu, Qianjiang; Kaur, Gagandeep; Khaliullin, Timur O.; Lafyatis, Robert; Lanna, Serafina; Li, Dongmei; Ma, Anjun; Morris, Alison; Muthumalage, Thivanka M.; Peters, Victor; Pryhuber, Gloria S.; Reader, Brenda F.; Rosas, Lorena; Sembrat, John C.; Shaikh, Sadiya; Shi, Hangchuan; Stacey, Sean D.; St Croix, Claudette; Wang, Cankun; Wang, Qixin; Watts, Andrew; Gu, Liangcai; Lin, Yiing; Rabinovitch, Peter S.; Sweetwyne, Mariya T.; Artyomov, Maxim N.; Ballentine, Samuel J.; Chheda, Milan G.; Davies, Sherri R.; DiPersio, John F.; Fields, Ryan C.; Fitzpatrick, James A. J.; Fulton, Robert S.; Imai, Shin-ichiro; Jain, Sanjay; Ju, Tao; Kushnir, Vladimir M.; Link, Daniel C.; Ben Major, Michael; Oh, Stephen T.; Rapp, Daniel; Rettig, Michael P.; Stewart, Shelia A.; Veis, Deborah J.; Vij, Kiran R.; Wendl, Michael C.; Wyczalkowski, Matthew A.; Craft, Joseph E.; Enninful, Archibald; Farzad, Negin; Gershkovich, Peter; Halene, Stephanie; Kluger, Yuval; VanOudenhove, Jennifer; Xu, Mina; Yang, Junchen; Yang, Mingyu Share Save
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Dietary restriction and the transcription factor clock delay eye aging to extend lifespan in Drosophila Melanogaster Hodge, Brian A.; Meyerhof, Geoffrey T.; Katewa, Subhash D.; Lian, Ting; Lau, Charles; Bar, Sudipta; Leung, Nicole Y.; Li, Menglin; Li-Kroeger, David; Melov, Simon; Schilling, Birgit; Montell, Craig; Kapahi, Pankaj Share Save
Genetic and metabolomic architecture of variation in diet restriction-mediated lifespan extension in Drosophila (vol 16, e1008835, 2020) Jin, Kelly; Wilson, Kenneth A.; Beck, Jennifer N.; Nelson, Christopher S.; Brownridge, George W.; Harrison, Benjamin R.; Djukovic, Danijel; Raftery, Daniel; Brem, Rachel B.; Yu, Shiqing; Drton, Mathias; Shojaie, Ali; Kapahi, Pankaj; Promislow, Daniel Share Save
A fly GWAS for purine metabolites identifies human FAM214 homolog medusa, which acts in a conserved manner to enhance hyperuricemia-driven pathologies by modulating purine metabolism and the inflammatory response Hilsabeck, Tyler A. U.; Liu-Bryan, Ru; Guo, Tracy; Wilson, Kenneth A.; Bose, Neelanjan; Raftery, Daniel; Beck, Jennifer N.; Lang, Sven; Jin, Kelly; Nelson, Christopher S.; Oron, Tal; Stoller, Marshall; Promislow, Daniel; Brem, Rachel B.; Terkeltaub, Robert; Kapahi, Pankaj Share Save
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