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Besim Öğretmen

medical university of south carolina

62H-index
276Paper Count
2.2WCitation Count
Published Papers 123
Publication Date
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Tumor and Stromal Sphingolipid Imbalance Are Associated with T Cell Tissue Residency in Glioblastoma
errCancers
IF4.4
err2026-07-28
err0
errOAAI
errChase M. Walton; Elif Percin; Han Gyul Lee; Odai Darawsha; Ben A. Strickland; Besim Ogretmen
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Proteome Responses to Acute Inhibition of De Novo Sphingolipid Synthesis Suggest Cancer Combination Therapies
errCancers
IF4.4
err2026-06-03
err0
errOAAI
errThi Thu Trang Luu; Dakai Zhang; Khaggeswar Bheemanapally; Masihuz Zaman; Zhiping Wu; Yang Liu; Xiaoqin Wu; Hyun-Eui Kim; Lei Zheng; Besim Ogretmen; Junmin Peng; Guangwei Du
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Sphingosine kinase-2 inhibition promotes immunogenic differentiation of myeloid-derived suppressor cells through an Acetyl-CoA carboxylase-phosphatidylcholine axis
errNature Communications
IF15.7
err2026-06-02
err0
errOAAI
errParamita Chakraborty; Shilpak Chatterjee; Mohamed Faisal Kassir; Wyatt Wofford; Seungho Choi; Natalia Oleinik; Ozge Saatci; Odai Darawshi; Satyajit Das; Nathaniel Oberhoeltzer; Anupam Gautam; Stephanie Mills; Reid DeMass; Zacharia Hedley; Yueying Liu; Rasesh Y. Parikh; Sandip Paul; Souvik Seal; Charles D. Smith; Michael B. Lilly; Vamsi K. Gangaraju; Yuri Peterson; Meenal Mehrotra; Elizabeth Hill; Ozgur Sahin; Norbert Leitinger; Paulo C. Rodriguez; Besim Ogretmen; Shikhar Mehrotra
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Phase II Trial of Opaganib Addition in Metastatic Castration-Resistant Prostate Cancer After Disease Progression on Abiraterone or Enzalutamide
errCancer Medicine
IF3.1
err2026-04-14
err0
errOAAI
errJacqueline T. Brown; Bassel Nazha; Anna C. Ferreira; Kent Armeson; Elizabeth G. Hill; Besim Ogretmen; Shikhar Mehrotra; Alan Brisendine; George Magrath; Terry F. Plasse; Theodore Stewart Gourdin; Omer Kucuk; Michael Lilly
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Palmitate-induced mitochondrial damage restricts histone acetylation in CD8 T cells to impair antitumor immunity
errScience Immunology
IF16.3
err2026-03-27
err0
PREAI
errSilvia Tiberti; Sara Gennari; Martina Romeo; Ilir Sheraj; Mohamed Faisal Kassir; Juan Fernández-García; Carina B. Nava Lauson; Roberta Noberini; Carlotta Catozzi; Tiziano Dallavilla; Mattia Ballerini; Alessia Loffreda; Simona G. Codreanu; Stacy D. Sherrod; Katrina L. Leaptrot; Alexandra C. Schrimpe-Rutledge; John A. McLean; Martin H. Schaefer; Simona Rodighiero; Tiziana Bonaldi; Sarah-Maria Fendt; Besim Ogretmen; Sara Sdelci; Luigi Nezi; Teresa Manzo
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Sphingolipid signaling links elastin deficiency to arterial hyper-muscularization and congenital heart disease
errNature Cardiovascular Research
IF10.8
err2026-01-05
err0
PREAI
errOdai Darawshi; Besim Ogretmen
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S1P transporter SPNS2 expression modulates T cell immune response
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errChoi, Seungho; Chakraborty, Paramita; Hedley, Zachariah; Lee, Han; Ogretmen, Besim; Mehrotra, Shikhar
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Beyond the Pseudogene: p17/PERMIT as a Mitochondrial Trafficking Protein Linking Aging and Neurodegeneration
errAging Cell
IF7.1
err2025-07-16
err0
errOAAI
errOnder Albayram; Natalia Oleinik; Besim Ogretmen
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Phosphorylation of an RNA-Binding Protein Rck/Me31b by Hippo Is Essential for Adipose Tissue Aging
errAGING CELL
IF7.1
err2025-03-11
err0
errOAAI
errYeom, Eunbyul; Mun, Hyejin; Lim, Jinhwan; Chun, Yoo Lim; Min, Kyung-Won; Lambert, Johana; Cowart, L. Ashley; Pierce, Jason S.; Ogretmen, Besim; Cho, Jung-Hyun; Chang, Jeong Ho; Buchan, J. Ross; Pitt, Jason; Kaeberlein, Matt; Kang, Sung-Ung; Kwon, Eun-Soo; Ko, Seungbeom; Choi, Kyoung-Min; Lee, Yong Sun; Ha, Yoon-Su; Kim, Seung-Jin; Lee, Kwang-Pyo; Kim, Hyo-Sung; Yang, Seo Young; Shin, Chang Hoon; Yoon, Je-Hyun; Lee, Kyu-Sun
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Pilot clinical trial of neoadjuvant toll-like receptor 7 agonist (Imiquimod) immunotherapy in early-stage oral squamous cell carcinoma
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2025-01-27
err0
errOAAI
errYoon, Angela J.; Carvajal, Richard D.; Graboyes, Evan M.; Kaczmar, John M.; Albergotti, William G.; Kejner, Alexandra E.; Troob, Scott H.; Philipone, Elizabeth; Anoma, Jean-Sebastien; Armeson, Kent E.; Hill, Elizabeth G.; Richardson, Mary S.; Woods, Tina R.; Chera, Bhishamjit S.; Nourollah-Zadeh, Farzad; Lee, Byung J.; Pandruvada, Subramanya; Kourtidis, Antonis; Kingsley, Christina; O'Quinn, Elizabeth C.; Mills, Stephanie; Jordan, Victoria C.; Spencer, Mike; Fails, Danielle; Mckee, Trevor D.; Zaidi, Mark; Brisendine, Alan; Horn, Shane; Mehrotra, Shikhar; Ogretmen, Besim; Newman, Jason G.
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H2S-Prdx4 axis mitigates Golgi stress to bolster tumor-reactive T cell immunotherapeutic response
errSCIENCE ADVANCES
IF12.5
err2024-11-15
err0
errOAAI
errOberholtzer, Nathaniel; Chakraborty, Paramita; Kassir, Mohamed Faisal; Dressman, James; Das, Satyajit; Mills, Stephanie; Comte-Walters, Susana; Gooz, Monika; Choi, Seungho; Parikh, Rasesh Y.; Hedley, Zacharia; Vaena, Silvia; Demass, Reid; Scurti, Gina; Romeo, Martin; Gangaraju, Vamsi K.; Berto, Stefano; Hill, Elizabeth; Ball, Lauren E.; Mehta, Anand S.; Maldonado, Eduardo N.; Nishimura, Michael I.; Ogretmen, Besim; Mehrotra, Shikhar
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Alterations of ceramide synthesis induce PD-L1 internalization and signaling to regulate tumor metastasis and immunotherapy response
errCELL REPORTS
IF6.9
err2024-08-01
err0
errOAAI
errWofford, Wyatt; Kim, Jisun; Kim, Dosung; Janneh, Alhaji H.; Lee, Han Gyul; Atilgan, Cansu; Oleinik, Natalia; Kassir, Mohamed Faisal; Saatci, Ozge; Chakraborty, Paramita; Tokat, Unal Metin; Gencer, Salih; Howley, Breege; Howe, Philip; Mehrotra, Shikhar; Sahin, Ozgur; Ogretmen, Besim
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Targeting LINC00152 activates cAMP/Ca2+/ferroptosis axis and overcomes tamoxifen resistance in ER plus breast cancer
errCELL DEATH & DISEASE
IF9.6
err2024-06-15
err7
errOAAI
errSaatci, Ozge; Alam, Rashedul; Huynh-Dam, Kim-Tuyen; Isik, Aynur; Uner, Meral; Belder, Nevin; Ersan, Pelin Gulizar; Tokat, Unal Metin; Ulukan, Burge; Cetin, Metin; Calisir, Kubra; Gedik, Mustafa Emre; Bal, Hilal; Sahin, Ozlem Sener; Riazalhosseini, Yasser; Thieffry, Denis; Gautheret, Daniel; Ogretmen, Besim; Aksoy, Sercan; Uner, Aysegul; Akyol, Aytekin; Sahin, Ozgur
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Golgihi T cells exhibit reduced susceptibility to exhaustion and improved tumor control
errCANCER RESEARCH
IF16.6
err2024-04-05
err0
PREAI
errOberholtzer, Nathaniel; Chakraborty, Paramita; Kassir, Mohamed Faisal; Dressman, James; Hedley, Zacharia; Scurti, Gina; Gooz, Monika; Ball, Lauren E.; Hill, Elizabeth; Mehta, Anand S.; Maldonado, Eduardo N.; Nishimura, Michael I.; Ogretmen, Besim; Mehrotra, Shikhar
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Transcriptome analysis of polyploid giant cancer cells and their progeny reveals a functional role for p21 in polyploidization and depolyploidization
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-04-01
err5
errOAAI
errWhite-Gilbertson, Shai; Lu, Ping; Saatci, Ozge; Sahin, Ozgur; Delaney, Joe R.; Ogretmen, Besim; Voelkel-Johnson, Christina
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Alzheimer's disease-associated amyloid precursor protein improves anti-tumor immunity by inhibiting ceramide-mediated lethal mitophagy and restoring mitochondrial fumarate metabolism in aging T-cells
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errKassir, Mohamed Faisal; Lee, Han G.; Oleinik, Natalia; Wofford, Wyatt; Walton, Chase; Atilgan, F. Cansu; Chakraborty, Paramita; Calisir, Kubra; Sahin, Ozgur; Mehrotra, Shikhar; Ogretmen, Besim
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errSave
Lipid metabolism alterations promote TNBC metastasis and immunotherapy resistance via PD-L1 internalization and signaling
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errWofford, Wyatt O.; Kim, Jisun; Kim, Dosung; Janneh, Alhaji H.; Lee, Han Gyul; Atilgan, F. Cansu; Oleinik, Natalia; Hill, Elizabeth; Saatci, Ozge; Gencer, Salih; Chakraborty, Paramita; Mehrotra, Shikhar; Sahin, Ozgur; Ogretmen, Besim
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errSave
p17/C18-ceramide-mediated mitophagy is an endogenous neuroprotective response in preclinical and clinical brain injury
errPNAS NEXUS
IF3.8
err2024-02-07
err1
errOAAI
errKarakaya, Eda; Oleinik, Natalia; Edwards, Jazlyn; Tomberlin, Jensen; Barker, Randy Bent; Berber, Burak; Ericsson, Maria; Alsudani, Habeeb; Ergul, Adviye; Beyaz, Semir; Lemasters, John J.; Ogretmen, Besim; Albayram, Onder
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errSave
The psychosine and galactosylceramide brain spatial distribution and its correlation with neuropathogenic processes
errMOLECULAR GENETICS AND METABOLISM
IF3.5
err2024-02-01
err0
PREAI
errBegum, Salma; Yan, Tingting; Ogretmen, Besim; Prentice, Boone; Maegawa, Gustavo
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Biomimetic Nanomaterials for the Immunomodulation of the Cardiosplenic Axis Postmyocardial Infarction
errADVANCED MATERIALS
IF26.8
err2023-11-27
err2
PREAI
errBose, Rajendran J. C.; Kessinger, Chase W.; Dhammu, Tajinder; Singh, Toolika; Shealy, Miller W.; Ha, Khanh; Collandra, Rena; Himbert, Sebastian; Garcia, Fernando J.; Oleinik, Natalia; Xu, Bing; Kontaridis, Maria I.; Rheinstadter, Maikel C.; Ogretmen, Besim; Menick, Donald R.; McCarthy, Jason R.
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Research Directions

No research directions
Co-authors
Cooperation Journals
S
Solomon H. Snyder
H-index: 222 · Papers: 1.2K
C
Carlo M. Croce
H-index: 209 · Papers: 1.8K
J
Jörge E. Cortes
H-index: 179 · Papers: 3.6K
K
Kwok‐Kin Wong
H-index: 140 · Papers: 1.7K
Y
Yusuf A. Hannun
H-index: 138 · Papers: 741
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