Daniel Kahne - Publications, H-index & Citations

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Daniel Kahne

Harvard University

85H-index

265Paper Count

2.5WCitation Count

Published Papers 132

Publication Date

Native β- barrel substrates pass through two shared intermediates during folding on the BAM complex

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-10-08

OAAI

dos Santos, Thiago M. A.; Thomson, Benjamin D.; Marquez, Melissa D.; Pan, Lydia; Monfared, Tabasom H.; Kahne, Daniel E.

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A Time-Resolved FRET Assay Identifies a Small Molecule that Inhibits the Essential Bacterial Cell Wall Polymerase FtsW

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2023-05-11

OAAI

Park, Youngseon; Taguchi, Atsushi; Baidin, Vadim; Kahne, Daniel; Walker, Suzanne

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Chloride Ions Are Required for Thermosipho africanus MurJ Function

MBIO

IF4.7

2023-02-28

OAAI

Kumar, Sujeet; Mollo, Aurelio; Rubino, Frederick A.; Kahne, Daniel; Ruiz, Natividad

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Suppressor Mutations in LptF Bypass Essentiality of LptC by Forming a Six-Protein Transenvelope Bridge That Efficiently Transports Lipopolysaccharide

MBIO

IF4.7

2023-02-28

OAAI

Falchi, Federica. A. A.; Taylor, Rebecca. J. J.; Rowe, Sebastian. J. J.; Moura, Elisabete C. C. M.; Baeta, Tiago; Laguri, Cedric; Simorre, Jean-Pierre; Kahne, Daniel. E. E.; Polissi, Alessandra; Sperandeo, Paola

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Genetic approaches to improve clorobiocin production in Streptomyces roseochromogenes NRRL 3504

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

IF4.3

2022-02-11

OAAI

Melnyk, Sofia; Stepanyshyn, Anastasia; Yushchuk, Oleksandr; Mandler, Michael; Ostash, Iryna; Koshla, Oksana; Fedorenko, Victor; Kahne, Daniel; Ostash, Bohdan

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The assembly of β-barrel outer membrane proteins

CURRENT OPINION IN MICROBIOLOGY

IF7.5

2021-04-01

OAAI

Tomasek, David; Kahne, Daniel

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Simple Secondary Amines Inhibit Growth of Gram-Negative Bacteria through Highly Selective Binding to Phenylalanyl-tRNA Synthetase

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2021-01-07

OAAI

Baidin, Vadim; Owens, Tristan W.; Lazarus, Michael B.; Kahne, Daniel

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Detection of Transport Intermediates in the Peptidoglycan Flippase MurJ Identifies Residues Essential for Conformational Cycling

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2020-03-04

OAAI

Rubino, Frederick A.; Mollo, Aurelio; Kumar, Sujeet; Butler, Emily K.; Ruiz, Natividad; Walker, Suzanne; Kahne, Daniel E.

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Chemical tools to characterize peptidoglycan synthases

CURRENT OPINION IN CHEMICAL BIOLOGY

IF6.1

2019-12-01

OAAI

Taguchi, Atsushi; Kahne, Daniel; Walker, Suzanne

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Formation of a β-barrel membrane protein is catalyzed by the interior surface of the assembly machine protein BamA

ELIFE

IF0

2019-11-14

OAAI

Lee, James; Tomasek, David; Santos, Thiago M. A.; May, Mary D.; Meuskens, Ina; Kahne, Daniel

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Combining Mutations That Inhibit Two Distinct Steps of the ATP Hydrolysis Cycle Restores Wild-Type Function in the Lipopolysaccharide Transporter and Shows that ATP Binding Triggers Transport

MBIO

IF4.7

2019-08-27

OAAI

Simpson, Brent W.; Pahil, Karanbir S.; Owens, Tristan W.; Lundstedt, Emily A.; Davis, Rebecca M.; Kahne, Daniel; Ruiz, Natividad

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Direction of Chain Growth and Substrate Preferences of Shape, Elongation, Division, and Sporulation-Family Peptidoglycan Glycosyltransferases

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2019-08-06

OAAI

Welsh, Michael A.; Schaefer, Kaitlin; Taguchi, Atsushi; Kahne, Daniel; Walker, Suzanne

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Pathway-Directed Screen for Inhibitors of the Bacterial Cell Elongation Machinery

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2019-01-01

OAAI

Buss, Jackson A.; Baidin, Vadim; Welsh, Michael A.; Flores-Kim, Josue; Cho, Hongbaek; Wood, B. McKay; Uehara, Tsuyoshi; Walker, Suzanne; Kahne, Daniel; Bernhardt, Thomas G.

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A central role for PBP2 in the activation of peptidoglycan polymerization by the bacterial cell elongation machinery

PLOS GENETICS

IF3.7

2018-10-18

115

OAAI

Rohs, Patricia D. A.; Buss, Jackson; Sim, Sue, I; Squyres, Georgia R.; Srisuknimit, Veerasak; Smith, Mandy; Cho, Hongbaek; Sjodt, Megan; Kruse, Andrew C.; Garner, Ethan C.; Walker, Suzanne; Kahne, Daniel E.; Bernhardt, Thomas G.

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Outer Membrane Translocon Communicates with Inner Membrane ATPase To Stop Lipopolysaccharide Transport

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2018-09-26

OAAI

Xie, Ran; Taylor, Rebecca J.; Kahne, Daniel

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Novobiocin Enhances Polymyxin Activity by Stimulating Lipopolysaccharide Transport

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2018-05-10

OAAI

Mandler, Michael D.; Baidin, Vadim; Lee, James; Pahil, Karanbir S.; Owens, Tristan W.; Kahne, Daniel

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Cell-based screen for discovering lipopolysaccharide biogenesis inhibitors

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-05-07

OAAI

Zhang, Ge; Baidin, Vadim; Pahil, Karanbir S.; Moison, Eileen; Tomasek, David; Ramadoss, Nitya S.; Chatterjee, Arnab K.; McNamara, Case W.; Young, Travis S.; Schultz, Peter G.; Meredith, Timothy C.; Kahne, Daniel

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Membrane Potential Is Required for MurJ Function

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2018-03-20

OAAI

Rubino, Frederick A.; Kumar, Sujeet; Ruiz, Natividad; Walker, Suzanne; Kahne, Daniel E.

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Antibiotic Combinations That Enable One-Step, Targeted Mutagenesis of Chromosomal Genes

ACS INFECTIOUS DISEASES

IF3.8

2018-03-13

OAAI

Lee, Wonsik; Do, Truc; Zhang, Ge; Kahne, Daniel; Meredith, Timothy C.; Walker, Suzanne

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Substrate binding to BamD triggers a conformational change in BamA to control membrane insertion

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-02-20

OAAI

Lee, James; Sutterlin, Holly A.; Wzorek, Joseph S.; Mandler, Michael D.; Hagan, Christine L.; Grabowicz, Marcin; Tomasek, David; May, Mary D.; Hart, Elizabeth M.; Silhavy, Thomas J.; Kahne, Daniel

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Research Directions