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SaveShare Save Bcl-xL targeting eliminates ageing tumor-promoting neutrophils and inhibits lung tumor growth
Bodac, Anita; Mayet, Abdullah; Rana, Sarika; Pascual, Justine; Bowler, Amber D.; Roh, Vincent; Fournier, Nadine; Craciun, Ligia; Demetter, Pieter; Radtke, Freddy; Meylan, Etienne Share Save Share Save Notch signaling drives intestinal graft-versus-host disease in mice and nonhuman primatesTkachev, Victor; Vanderbeck, Ashley; Perkey, Eric; Furlan, Scott N.; McGuckin, Connor; Atria, Daniela Gomez; Gerdemann, Ulrike; Rui, Xianliang; Lane, Jennifer; Hunt, Daniel J.; Zheng, Hengqi; Colonna, Lucrezia; Hoffman, Michelle; Yu, Alison; Outen, Riley; Kelly, Samantha; Allman, Anneka; Koch, Ute; Radtke, Freddy; Ludewig, Burkhard; Burbach, Brandon; Shimizu, Yoji; Panoskaltsis-Mortari, Angela; Chen, Guoying; Carpenter, Stephen M.; Harari, Olivier; Kuhnert, Frank; Thurston, Gavin; Blazar, Bruce R.; Kean, Leslie S.; Maillard, Ivan Share Save Share Save Disruption of stem cell niche-confined R-spondin 3 expression leads to impaired hematopoiesisKurtova, Antonina, V; Heinlein, Melanie; Haas, Simon; Velten, Lars; Dijkgraaf, Gerrit J. P.; Storm, Elaine E.; Kljavin, Noelyn M.; Boumahdi, Soufiane; Himmels, Patricia; Herault, Aurelie; Mancini, Andrew; Koeppen, Hartmut; Dail, Monique; Yan, Qingxiang; Zhang, Jianhuan; Koch, Ute; Radtke, Freddy; Modrusan, Zora; Metcalfe, Ciara; Piskol, Robert; de Sauvage, Frederic J. Share Save Stromal Notch ligands foster lymphopenia-driven functional plasticity and homeostatic proliferation of naive B cellsAtria, Daniela Gomez; Gaudette, Brian T.; Londregan, Jennifer; Kelly, Samantha; Perkey, Eric; Allman, Anneka; Srivastava, Bhaskar; Koch, Ute; Radtke, Freddy; Ludewig, Burkhard; Siebel, Christian W.; Ryan, Russell Jh; Robertson, Tanner F.; Burkhardt, Janis K.; Pear, Warren S.; Allman, David; Maillard, Ivan Share Save A leukemia-protective germline variant mediates chromatin module formation via transcription factor nucleationLlimos, Gerard; Gardeux, Vincent; Koch, Ute; Kribelbauer, Judith F.; Hafner, Antonina; Alpern, Daniel; Pezoldt, Joern; Litovchenko, Maria; Russeil, Julie; Dainese, Riccardo; Moia, Riccardo; Mahmoud, Abdurraouf Mokhtar; Rossi, Davide; Gaidano, Gianluca; Plass, Christoph; Lutsik, Pavlo; Gerhauser, Clarissa; Waszak, Sebastian M.; Boettiger, Alistair; Radtke, Freddy; Deplancke, Bart Share Save The E protein-TCF1 axis controls γδ T cell development and effector fateFahl, Shawn P.; Contreras, Alejandra, V; Verma, Anjali; Qiu, Xiang; Harly, Christelle; Radtke, Freddy; Zuniga-Pflucker, Juan Carlos; Murre, Cornelis; Xue, Hai-Hui; Sen, Jyoti Misra; Wiest, David L. Share Save Share Save Pharmacological disruption of the Notch transcription factor complexLehal, Rajwinder; Zaric, Jelena; Vigolo, Michele; Urech, Charlotte; Frismantas, Viktoras; Zangger, Nadine; Cao, Linlin; Berger, Adeline; Chicote, Irene; Loubery, Sylvain; Choi, Sung Hee; Koch, Ute; Blacklow, Stephen C.; Palmer, Hector G.; Bornhauser, Beat; Gonzalez-Gaitan, Marcos; Arsenijevic, Yvan; Zoete, Vincent; Aster, Jon C.; Bourquin, Jean-Pierre; Radtke, Freddy Share Save GCNT1-Mediated O-Glycosylation of the Sialomucin CD43 Is a Sensitive Indicator of Notch Signaling in Activated T CellsPerkey, Eric; De Sousa, Dave Maurice; Carrington, Leolene; Chung, Jooho; Dils, Alexander; Granadier, David; Koch, Ute; Radtke, Freddy; Ludewig, Burkhard; Blazar, Bruce R.; Siebel, Christian W.; Brennan, Todd, V; Nolz, Jeffrey; Labrecque, Nathalie; Maillard, Ivan Share Save Canonical Notch signaling controls the early thymic epithelial progenitor cell state and emergence of the medullary epithelia lineage in fetal thymus developmentLiu, Dong; Kousa, Anastasia, I; O'Neill, Kathy E.; Rouse, Paul; Popis, Martyna; Farley, Alison M.; Tomlinson, Simon R.; Ulyanchenko, Svetlana; Guillemot, Francois; Seymour, Philip A.; Jorgensen, Mette C.; Serup, Palle; Koch, Ute; Radtke, Freddy; Blackburn, C. Clare Share Save Neutrophils suppress tumor-infiltrating T cells in colon cancer via matrix metalloproteinase-mediated activation of TGFβGermann, Markus; Zangger, Nadine; Sauvain, Marc-Olivier; Sempoux, Christine; Bowler, Amber D.; Wirapati, Pratyaksha; Kandalaft, Lana E.; Delorenzi, Mauro; Tejpar, Sabine; Coukos, George; Radtke, Freddy Share Save Share Save Triggering of a Dll4-Notch1 loop impairs wound healing in diabetesZheng, Xiaowei; Narayanan, Sampath; Sunkari, Vivekananda Gupta; Eliasson, Sofie; Botusan, Ileana Ruxandra; Grunler, Jacob; Catrina, Anca Irinel; Radtke, Freddy; Xu, Cheng; Zhao, Allan; Ekberg, Neda Rajamand; Lendahl, Urban; Catrina, Sergiu-Bogdan Share Save Share Save AMPK promotes survival of c-Myc-positive melanoma cells by suppressing oxidative stressKfoury, Alain; Armaro, Marzia; Collodet, Caterina; Sordet-Dessimoz, Jessica; Giner, Maria Pilar; Christen, Stefan; Moco, Sofia; Leleu, Marion; de Leval, Laurence; Koch, Ute; Trumpp, Andreas; Sakamoto, Kei; Beermann, Friedrich; Radtke, Freddy Share Save Notch2 Signaling Maintains NSC Quiescence in the Murine Ventricular-Subventricular ZoneEngler, Anna; Rolando, Chiara; Giachino, Claudio; Saotome, Ichiko; Erni, Andrea; Brien, Callum; Zhang, Runrui; Zimber-Strobl, Ursula; Radtke, Freddy; Artavanis-Tsakonas, Spyros; Louvi, Angeliki; Taylor, Verdon Share Save 
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