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Dana J. Philpott

university of toronto

93H-index
373Paper Count
3.4WCitation Count
Published Papers 167
Publication Date
NLRC5-Deficient Macrophages Promote a Tumor-Permissive Phenotype via AXL- and MERTK-Mediated Efferocytosis
err2026-08-19
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errOAAI
errShambel Araya Haile; Alessandra Gatta; Nina Colon; Dana J. Philpott; Thomas A. Kufer; Le Ying; Dongmei Tong; Richard L. Ferrero
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Endothelial cell-intrinsic NOD2 signaling regulates the intestinal immune response through the generation of effector and memory T cells
err2026-07-20
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PREAI
errBoyan K. Tsankov; Madison Denney; Jennifer S. Y. Ahn; Charles Carr; Nayanan Nathan; Derek K. L. Tsang; Giuliano Bayer; Lauren Baerg; Alexander Luchak; Tapas Mukherjee; Elaine Tam; Bana Samman; Jennifer L. Gommerman; Stephen E. Girardin; Dana J. Philpott
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New Perspectives on Paracrine IL-18 Signaling in the Intestinal Epithelium
err2025-08-20
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PREAI
errNathaniel J. Winsor; Adrienne Ranger; Ojas Singh; Dana J. Philpott; Stephen E. Girardin
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Bacterial ADP-heptose triggers stem cell regeneration in the intestinal epithelium following injury
err2025-07-11
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PREAI
errShawn Goyal; Cynthia X. Guo; Ojas Singh; Adrienne Ranger; Caitlin F. Harrigan; Justin Meade; Alexander Luchak; Derek K. Tsang; Herbert Y. Gaisano; Nan Gao; Scott A. Yuzwa; Jeffrey L. Wrana; Dana J. Philpott; Scott D. Gray-Owen; Stephen E. Girardin
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Quantifying the intra- and inter-species community interactions in microbiomes by dynamic covariance mapping
err2025-07-09
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errOAAI
errMelis Gencel; Gisela Marrero Cofino; Cang Hui; Zahra Sahaf; Louis Gauthier; Chloé Matta; David Gagné-Leroux; Derek K. L. Tsang; Dana P. Philpott; Sheela Ramathan; Alfredo Menendez; Shimon Bershtein; Adrian W. R. Serohijos
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Gasdermin-D pores induce an inactivating caspase-4 cleavage that limits IL-18 production in the intestinal epithelium
err2025-05-13
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errOAAI
errBruce, J. K.; Li, L. Y.; Tang, Y.; Forster, E. G.; Winsor, N. J.; Bi, P. Y.; Krustev, C.; Keely, S.; Lee, J. E.; Rohde, J. R.; Gaisano, H. Y.; Philpott, D. J.; Girardin, S. E.
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Cross-kingdom-mediated detection of intestinal protozoa through NLRP6
err2025-03-01
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PREAI
errWinsor, Nathaniel J.; Bayer, Giuliano; Singh, Ojas; Chan, Jeremy K.; Li, Lu Yi; Lieng, Brandon Y.; Foerster, Elisabeth; Popovic, Ana; Tsankov, Boyan K.; Maughan, Heather; Lemire, Paul; Tam, Elaine; Streutker, Catherine; Chen, Lina; Heaver, Stacey L.; Ley, Ruth E.; Parkinson, John; Montenegro-Burke, J. Rafael; Birchenough, George M. H.; Philpott, Dana J.; Girardin, Stephen E.
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A Role for NOD2 in Intestinal Memory T cell Formation and Function
err2024-05-01
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PREAI
errTsankov, Boyan; Carr, Charles; Nathan, Nayanan; Bayer, Giuliano; Philpott, Dana
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The intestinal microbiota modulates the transcriptional landscape of iNKT cells at steady-state and following antigen exposure
err2024-04-01
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errOAAI
errLin, Qiaochu; Kuypers, Meggie; Baglaenko, Yuriy; Cao, Eric; Hezaveh, Kebria; Despot, Tijana; Herbozo, Carolina de Amat; Tleugabulova, Mayra Cruz; Umana, Juan Mauricio; McGaha, Tracy L.; Philpott, Dana J.; Mallevaey, Thierry
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Cytosolic retention of HtrA2 during mitochondrial protein import stress triggers the DELE1-HRI pathway
err2024-03-30
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errOAAI
errBi, Paul Y.; Killackey, Samuel A.; Schweizer, Linus; Arnoult, Damien; Philpott, Dana J.; Girardin, Stephen E.
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The effects of NOD-like receptors on adaptive immune responses
err2024-02-01
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errOAAI
errTsankov, Boyan K.; Luchak, Alexander; Carr, Charles; Philpott, Dana J.
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The NF-κB signaling system in the immunopathogenesis of inflammatory bowel disease
err2024-01-09
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PREAI
errMukherjee, Tapas; Kumar, Naveen; Chawla, Meenakshi; Philpott, Dana J.; Basak, Soumen
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Gut microbiota promotes stem cell differentiation through macrophage and mesenchymal niches in early postnatal development (vol 55, pg 2300, 2022)
errIMMUNITY
IF26.3
err2023-09-01
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errOAAI
errKim, Ji-Eun; Li, Bo; Fei, Lijiang; Horne, Rachael; Lee, Dorothy; Loe, Adrian Kwan Ho; Miyake, Hiromu; Ayar, Eda; Gurma, Maria; Kim, Dae-Kyum; Surette, Michael G.; Philpott, Dana J.; Sherman, Philip; Guo, Guoji; Pierro, Agostino; Kim, Tae-Hee
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NOD1 mediates interleukin-18 processing in epithelial cells responding to Helicobacter pylori infection in mice
err2023-06-26
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errOAAI
errTran, L. S.; Ying, L.; D'Costa, K.; Wray-McCann, G.; Kerr, G.; Le, L.; Allison, C. C.; Ferrand, J.; Chaudhry, H.; Emery, J.; De Paoli, A.; Colon, N.; Creed, S.; Kaparakis-Liaskos, M.; Como, J.; Dowling, J. K.; Johanesen, P. A.; Kufer, T. A.; Pedersen, J. S.; Mansell, A.; Philpott, D. J.; Elgass, K. D.; Abud, H. E.; Nachbur, U.; Croker, B. A.; Masters, S. L.; Ferrero, R. L.
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Recent Thymic Emigrants Require RBPJ-Dependent Notch Signaling to Transition into Functionally Mature Naive T Cells
err2023-05-08
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errOAAI
errTeichman, Sintia; Wang, Helen; Lee, Christina R.; Mohtashami, Mahmood; Foerster, Elisabeth; Han, Jianxun; Trotman-Grant, Ashton C.; Winer, Shawn; Tsui, Hubert; Philpott, Dana J.; Zuniga-Pflucker, Juan Carlos
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Gut microbiome modified by bariatric surgery improves insulin sensitivity and correlates with increased brown fat activity and energy expenditure
err2023-05-01
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errOAAI
errYadav, Jitender; Liang, Tao; Qin, Taira; Nathan, Nayanan; Schwenger, Katherine J. P.; Pickel, Lauren; Xie, Li; Lei, Helena; Winer, Daniel A.; Maughan, Heather; Robertson, Susan J.; Woo, Minna; Lou, Wendy; Banks, Kate; Jackson, Timothy; Okrainec, Allan; Hota, Susy S.; Poutanen, Susan M.; Sung, Hoon-Ki; Allard, Johane P.; Philpott, Dana J.; Gaisano, Herbert Y.
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ATG16L1 protects from interferon-γ-induced cell death in the small intestinal crypt
err2023-04-01
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errOAAI
errFoerster, Elisabeth G.; Tsang, Derek K. L.; Goyal, Shawn; Robertson, Susan J.; Robert, Lukian M.; Maughan, Heather; Streutker, Catherine J.; Girardin, Stephen E.; Philpott, Dana J.
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Isoginkgetin, a Natural Biflavonoid Proteasome Inhibitor, Sensitizes Cancer Cells to Apoptosis via Disruption of Lysosomal Homeostasis and Impaired Protein Clearance
err2023-03-03
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errOAAI
errTsalikis, Jessica; Abdel-Nour, Mena; Farahvash, Armin; Sorbara, Matthew T.; Poon, Stephanie; Philpott, Dana J.; Girardin, Stephen E.
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