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Phase II open label trial of Minnelide™ in patients with chemotherapy refractory metastatic pancreatic cancer Propper, David; Borazanci, Erkut; O'Dwyer, Peter J.; Von Hoff, Daniel; Hartlebury, Joseph; Antal, Corina E.; Evan, Gerard I.; Han, HaiYong; Downes, Michael; Evans, Ronald; Rabinowitz, Joshua; Petricoin, Emmanuel; Saluja, Ashok; Velagapudi, Mohana; Patel, Hitendra Share Save
A super-enhancer-regulated RNA-binding protein cascade drives pancreatic cancer Antal, Corina E.; Oh, Tae Gyu; Aigner, Stefan; Luo, En-Ching; Yee, Brian A.; Campos, Tania; Tiriac, Herve; Rothamel, Katherine L.; Cheng, Zhang; Jiao, Henry; Wang, Allen; Hah, Nasun; Lenkiewicz, Elizabeth; Lumibao, Jan C.; Truitt, Morgan L.; Estepa, Gabriela; Banayo, Ester; Bashi, Senada; Esparza, Edgar; Munoz, Ruben M.; Diedrich, Jolene K.; Sodir, Nicole M.; Mueller, Jasmine R.; Fraser, Cory R.; Borazanci, Erkut; Propper, David; Von Hoff, Daniel D.; Liddle, Christopher; Yu, Ruth T.; Atkins, Annette R.; Han, Haiyong; Lowy, Andrew M.; Barrett, Michael T.; Engle, Dannielle D.; Evan, Gerard I.; Yeo, Gene W.; Downes, Michael; Evans, Ronald M. Share Save
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p53 Restoration in Induction and Maintenance of Senescence: Differential Effects in Premalignant and Malignant Tumor Cells Harajly, Mohamad; Zalzali, Hasan; Nawaz, Zafar; Ghayad, Sandra E.; Ghamloush, Farah; Basma, Hussein; Zainedin, Samiha; Rabeh, Wissam; Jabbour, Mark; Tawil, Ayman; Badro, Danielle A.; Evan, Gerard I.; Saab, Raya Share Save
Reversible Myc hypomorphism identifies a key Myc-dependency in early cancer evolution Sodir, Nicole M.; Pellegrinet, Luca; Kortlever, Roderik M.; Campos, Tania; Kwon, Yong-Won; Kim, Shinseog; Garcia, Daniel; Perfetto, Alessandra; Anastasiou, Panayiotis; Swigart, Lamorna Brown; Arends, Mark J.; Littlewood, Trevor D.; Evan, Gerard, I Share Save
Clonal somatic copy number altered driver events inform drug sensitivity in high-grade serous ovarian cancer Martins, Filipe Correia; Couturier, Dominique-Laurent; de Santiago, Ines; Sauer, Carolin Margarethe; Vias, Maria; Angelova, Mihaela; Sanders, Deborah; Piskorz, Anna; Hall, James; Hosking, Karen; Amirthanayagam, Anumithra; Cosulich, Sabina; Carnevalli, Larissa; Davies, Barry; Watkins, Thomas B. K.; Funingana, Ionut G.; Bolton, Helen; Haldar, Krishnayan; Latimer, John; Baldwin, Peter; Crawford, Robin; Eldridge, Matthew; Basu, Bristi; Jimenez-Linan, Mercedes; Mcpherson, Andrew W.; McGranahan, Nicholas; Litchfield, Kevin; Shah, Sohrab P.; McNeish, Iain; Caldas, Carlos; Evan, Gerard; Swanton, Charles; Brenton, James D. Share Save
Wnt signaling promotes oncogenic transformation by inhibiting c-Myc-induced apoptosis (vol 157, pg 429, 2002) You, Zongbing; Saims, Daniel; Chen, Shaoqiong; Zhang, Zhaocheng; Guttridge, Denis C.; Guan, Kun-liang; MacDougald, Ormond A.; Brown, Anthony M. C.; Evan, Gerard; Kitajewski, Jan; Wang, Cun-Yu Share Save
The Wnt signaling receptor Fzd9 is essential for Myc-driven tumorigenesis in pancreatic islets Zacarias-Fluck, Mariano F.; Jauset, Toni; Martinez-Martin, Sandra; Kaur, Jastrinjan; Casacuberta-Serra, Silvia; Masso-Valles, Daniel; Serrano del Pozo, Erika; Martin-Fernandez, Genesis; Gonzalez-Larreategui, Inigo; Lopez-Estevez, Sergio; Brown-Swigart, Lamorna; Beaulieu, Marie-Eve; Whitfield, Jonathan R.; Madan, Babita; Virshup, David M.; Evan, Gerard, I; Soucek, Laura Share Save
Lipid Remodeling in Hepatocyte Proliferation and Hepatocellular Carcinoma Hall, Zoe; Chiarugi, Davide; Charidemou, Evelina; Leslie, Jack; Scott, Emma; Pellegrinet, Luca; Allison, Michael; Mocciaro, Gabriele; Anstee, Quentin M.; Evan, Gerard, I; Hoare, Matthew; Vidal-Puig, Antonio; Oakley, Fiona; Vacca, Michele; Griffin, Julian L. Share Save
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Reactivation of Myc transcription in the mouse heart unlocks its proliferative capacity Bywater, Megan J.; Burkhart, Deborah L.; Straube, Jasmin; Sabo, Arianna; Pendino, Vera; Hudson, James E.; Quaife-Ryan, Gregory A.; Porrello, Enzo R.; Rae, James; Parton, Robert G.; Kress, Theresia R.; Amati, Bruno; Littlewood, Trevor D.; Evan, Gerard, I; Wilson, Catherine H. Share Save
MYC Instructs and Maintains Pancreatic Adenocarcinoma Phenotype Sodir, Nicole M.; Kortlever, Roderik M.; Barthet, Valentin J. A.; Campos, Tania; Pellegrinet, Luca; Kupczak, Steven; Anastasiou, Panayiotis; Swigart, Lamorna Brown; Soucek, Laura; Arends, Mark J.; Littlewood, Trevor D.; Evan, Gerard I. Share Save
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