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Comprehensive Association Analyses of Extraintestinal Manifestations in Inflammatory Bowel Disease Khrom, Michelle; Long, Millie; Dube, Shishir; Robbins, Lori; Botwin, Gregory J.; Yang, Shaohong; Mengesha, Emebet; Li, Dalin; Naito, Takeo; Bonthala, Nirupama N.; Ha, Christina; Melmed, Gil; Rabizadeh, Shervin; Syal, Gaurav; Vasiliauskas, Eric; Ziring, David; Brant, Steven R.; Cho, Judy; Duerr, Richard H.; Rioux, John; Schumm, Phil; Silverberg, Mark; Ananthakrishnan, Ashwin N.; Faubion, William A.; Jabri, Bana; Lira, Sergio A.; Newberry, Rodney D.; Sandler, Robert S.; Xavier, Ramnik J.; Kugathasan, Subra; Hercules, David; Targan, Stephan R.; Sartor, R. Balfour; Haritunians, Talin; Mcgovern, Dermot P. B. Share Save
Clinical Predictors of Early and Late Endoscopic Recurrence Following Ileocolonic Resection in Crohn's Disease Hernandez-Rocha, Cristian; Walshe, Margaret; Birch, Sondra; Sabic, Ksenija; Korie, Ujunwa; Chasteau, Colleen; Miladinova, Vessela M.; Sabol, William B.; Mengesha, Emebet; Hanna, Mary; Pozdnyakova, Valeriya; Datta, Lisa; Kohen, Rita; Milgrom, Raquel; Stempak, Joanne M.; Bitton, Alain; Brant, Steven R.; Rioux, John D.; McGovern, Dermot P. B.; Duerr, Richard H.; Cho, Judy H.; Schumm, Phil L.; Silverberg, Mark S.; Lazarev, Mark Share Save
The role of admixture in the rare variant contribution to inflammatory bowel disease Astore, Courtney; Sharma, Shivam; Nagpal, Sini; Cutler, David J.; Rioux, John D.; Cho, Judy H.; Mcgovern, Dermot P. B.; Brant, Steven R.; Kugathasan, Subra; Jordan, I. King; Gibson, Greg Share Save
Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries Liu, Zhanju; Liu, Ruize; Gao, Han; Jung, Seulgi; Gao, Xiang; Sun, Ruicong; Liu, Xiaoming; Kim, Yongjae; Lee, Ho-Su; Kawai, Yosuke; Nagasaki, Masao; Umeno, Junji; Tokunaga, Katsushi; Kinouchi, Yoshitaka; Masamune, Atsushi; Shi, Wenzhao; Shen, Chengguo; Guo, Zhenglin; Yuan, Kai; Zhu, Shu; Li, Dalin; Liu, Jianjun; Ge, Tian; Cho, Judy; Daly, Mark J.; McGovern, Dermot P. B.; Ye, Byong Duk; Song, Kyuyoung; Kakuta, Yoichi; Li, Mingsong; Huang, Hailiang; Abreu, Maria; Achkar, Jean-Paul; Andersen, Vibeke; Bernstein, Charles; Brant, Steven R.; Bujanda, Luis; Ng, Siew Chien; Cho, Judy; Daly, Mark J.; Denson, Lee A.; Duerr, Richard H.; Ferguson, Lynnette R.; Franchimont, Denis; Franke, Andre; Gearry, Richard; Hakonarson, Hakon; Halfvarson, Jonas; Heller, Caren; Huang, Hailiang; Julia, Antonio; Kelsen, Judith; Khalili, Hamed; Kugathasan, Subramaniam; Kupcinskas, Juozas; Latiano, Anna; Louis, Edouard; Malekzadeh, Reza; McCauley, Jacob L.; McGovern, Dermot P. B.; Moran, Christopher; Okou, David; Orchard, Tim; Palotie, Aarno; Parkes, Miles; Pekow, Joel; Potocnik, Uros; Radford-Smith, Graham; Rioux, John D.; Rogler, Gerhard; Sands, Bruce; Silverberg, Mark; Sokol, Harry; Vermeire, Severine; Weersma, Rinse K.; Xavier, Ramnik J.; Hu, Naizhong; Cao, Qian; Wang, Yufang; Miao, Yinglei; Zhang, Hongjie; Lv, Xiaoping; Gao, Xiang; Zhang, Hu; Su, Jingling; Feng, Baisui; Zhao, Ye; Zhu, Liangru; Chen, Yan; Zhu, Lanxiang; Chen, Chunxiao; Wang, Yali; Wang, Yingde; Pang, Zhi; Chen, Yingxuan; Zhang, Xiaolan; Li, Hui; Yu, Qin; Ye, Mei; Zhang, Sumin; Tang, Wen; Wang, Mei; Cao, Xiaocang; Zhu, Ruixin; Zhou, Guangxi; Bian, Zhaolian; Guo, Xiaofeng; Wu, Xiaoli; Liu, Jinchun; Xu, Wei; Li, Yuqin; Guo, Qin; Guo, Zhiguo; Li, Mingsong; Liu, Zhanju Share Save
Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease patients Wu, Yiming; Gettler, Kyle; Kars, Meltem Ece; Giri, Mamta; Li, Dalin; Bayrak, Cigdem Sevim; Zhang, Peng; Jain, Aayushee; Maffucci, Patrick; Sabic, Ksenija; Van Vleck, Tielman; Nadkarni, Girish; Denson, Lee A.; Ostrer, Harry; Levine, Adam P.; Schiff, Elena R.; Segal, Anthony W.; Kugathasan, Subra; Stenson, Peter D.; Cooper, David N.; Schumm, L. Philip; Snapper, Scott; Daly, Mark J.; Haritunians, Talin; Duerr, Richard H.; Silverberg, Mark S.; Rioux, John D.; Brant, Steven R.; McGovern, Dermot P. B.; Cho, Judy H.; Itan, Yuval Share Save
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Prostaglandins and calprotectin are genetically and functionally linked to the Inflammatory Bowel Diseases Karaky, Mohamad; Boucher, Gabrielle; Mola, Sarai; Foisy, Sylvain; Beauchamp, Claudine; Rivard, Marie-Eve; Burnette, Melanie; Gosselin, Hugues; Bitton, Alain; Charron, Guy; Goyette, Philippe; Rioux, John D. Share Save
Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility Sazonovs, Aleksejs; Stevens, Christine R.; Venkataraman, Guhan R.; Yuan, Kai; Avila, Brandon; Abreu, Maria T.; Ahmad, Tariq; Allez, Matthieu; Ananthakrishnan, Ashwin N.; Atzmon, Gil; Baras, Aris; Barrett, Jeffrey C.; Barzilai, Nir; Beaugerie, Laurent; Beecham, Ashley; Bernstein, Charles N.; Bitton, Alain; Bokemeyer, Bernd; Chan, Andrew; Chung, Daniel; Cleynen, Isabelle; Cosnes, Jacques; Cutler, David J.; Daly, Allan; Damas, Oriana M.; Datta, Lisa W.; Dawany, Noor; Devoto, Marcella; Dodge, Sheila; Ellinghaus, Eva; Fachal, Laura; Farkkila, Martti; Faubion, William; Ferreira, Manuel; Franchimont, Denis; Gabriel, Stacey B.; Ge, Tian; Georges, Michel; Gettler, Kyle; Giri, Mamta; Glaser, Benjamin; Goerg, Siegfried; Goyette, Philippe; Graham, Daniel; Hamalainen, Eija; Haritunians, Talin; Heap, Graham A.; Hiltunen, Mikko; Hoeppner, Marc; Horowitz, Julie E.; Irving, Peter; Iyer, Vivek; Jalas, Chaim; Kelsen, Judith; Khalili, Hamed; Kirschner, Barbara S.; Kontula, Kimmo; Koskela, Jukka T.; Kugathasan, Subra; Kupcinskas, Juozas; Lamb, Christopher A.; Laudes, Matthias; Levesque, Chloe; Levine, Adam P.; Lewis, James D.; Liefferinckx, Claire; Loescher, Britt-Sabina; Louis, Edouard; Mansfield, John; May, Sandra; McCauley, Jacob L.; Mengesha, Emebet; Mni, Myriam; Moayyedi, Paul; Moran, Christopher J.; Newberry, Rodney D.; O'Charoen, Sirimon; Okou, David T.; Oldenburg, Bas; Ostrer, Harry; Palotie, Aarno; Paquette, Jean; Pekow, Joel; Peter, Inga; Pierik, Marieke J.; Ponsioen, Cyriel Y.; Pontikos, Nikolas; Prescott, Natalie; Pulver, Ann E.; Rahmouni, Souad; Rice, Daniel L.; Saavalainen, Paivi; Sands, Bruce; Sartor, R. Balfour; Schiff, Elena R.; Schreiber, Stefan; Schumm, L. Philip; Segal, Anthony W.; Seksik, Philippe; Shawky, Rasha; Sheikh, Shehzad Z.; Silverberg, Mark S.; Simmons, Alison; Skeiceviciene, Jurgita; Sokol, Harry; Solomonson, Matthew; Somineni, Hari; Sun, Dylan; Targan, Stephan; Turner, Dan; Uhlig, Holm H.; van der Meulen, Andrea E.; Vermeire, Severine; Verstockt, Sare; Voskuil, Michiel D.; Winter, Harland S.; Young, Justine; Duerr, Richard H.; Franke, Andre; Brant, Steven R.; Cho, Judy; Weersma, Rinse K.; Parkes, Miles; Xavier, Ramnik J.; Rivas, Manuel A.; Rioux, John D.; McGovern, Dermot P. B.; Huang, Hailiang; Anderson, Carl A.; Daly, Mark J. Share Save
IBD-associated G protein-coupled receptor 65 variant compromises signalling and impairs key functions involved in inflammation Mercier, Virginie; Boucher, Gabrielle; Devost, Dominic; Bourque, Kyla; Alikashani, Azadeh; Beauchamp, Claudine; Bitton, Alain; Foisy, Sylvain; Goyette, Philippe; Charron, Guy; Hebert, Terence E.; Rioux, John D. Share Save
Human enteric viruses autonomously shape inflammatory bowel disease phenotype through divergent innate immunomodulation Adiliaghdam, Fatemeh; Amatullah, Hajera; Digumarthi, Sreehaas; Saunders, Tahnee L.; Rahman, Raza-Ur; Wong, Lai Ping; Sadreyev, Ruslan; Droit, Lindsay; Paquette, Jean; Goyette, Philippe; Rioux, John D.; Hodin, Richard; Mihindukulasuriya, Kathie A.; Handley, Scott A.; Jeffrey, Kate L. Share Save
Functional screen of inflammatory bowel disease genes reveals key epithelial functions Ntunzwenimana, Jessy Carol; Boucher, Gabrielle; Paquette, Jean; Gosselin, Hugues; Alikashani, Azadeh; Morin, Nicolas; Beauchamp, Claudine; Thauvette, Louise; Rivard, Marie-Eve; Dupuis, Frederique; Deschenes, Sonia; Foisy, Sylvain; Latour, Frederic; Lavallee, Genevieve; Daly, Mark J.; Xavier, Ramnik J.; Charron, Guy; Goyette, Philippe; Rioux, John D. Share Save
A Role for CXCR3 Ligands as Biomarkers of Post-Operative Crohn's Disease Recurrence Walshe, Margaret; Nayeri, Shadi; Ji, Jiayi; Hernandez-Rocha, Cristian; Sabic, Ksenija; Hu, Liangyuan; Giri, Mamta; Nayar, Shikha; Brant, Steven; McGovern, Dermot P. B.; Rioux, John D.; Duerr, Richard H.; Cho, Judy H.; Schumm, Phil L.; Lazarev, Mark; Silverberg, Mark S. Share Save
Inflamed Ulcerative Colitis Regions Associated With MRGPRX2-Mediated Mast Cell Degranulation and Cell Activation Modules, Defining a New Therapeutic Target Chen, Ernie; Chuang, Ling-Shiang; Giri, Mamta; Villaverde, Nicole; Hsu, Nai-Yun; Sabic, Ksenija; Joshowitz, Sari; Gettler, Kyle; Nayar, Shikha; Chai, Zhi; Alter, Isaac L.; Chasteau, Colleen C.; Korie, Ujunwa M.; Dzedzik, Siarhei; Thin, Tin Htwe; Jain, Aayushee; Moscati, Arden; Bongers, Gerardus; Duerr, Richard H.; Silverberg, Mark S.; Brant, Steven R.; Rioux, John D.; Peter, Inga; Schumm, L. Philip; Haritunians, Talin; McGovern, Dermot P.; Itan, Yuval; Cho, Judy H. Share Save
Common and Rare Variant Prediction and Penetrance of IBD in a Large, Multi-ethnic, Health System-based Biobank Cohort Gettler, Kyle; Levantovsky, Rachel; Moscati, Arden; Giri, Mamta; Wu, Yiming; Hsu, Nai-Yun; Chuang, Ling-Shiang; Sazonovs, Aleksejs; Venkateswaran, Suresh; Korie, Ujunwa; Chasteau, Colleen; Duerr, Richard H.; Silverberg, Mark S.; Snapper, Scott B.; Daly, Mark J.; McGovern, Dermot P.; Brant, Steven R.; Rioux, John D.; Kugathasan, Subra; Anderson, Carl A.; Itan, Yuval; Cho, Judy H. Share Save
Whole-genome sequencing of African Americans implicates differential genetic architecture in inflammatory bowel disease Somineni, Hari K.; Nagpal, Sini; Venkateswaran, Suresh; Cutler, David J.; Okou, David T.; Haritunians, Talin; Simpson, Claire L.; Begum, Ferdouse; Datta, Lisa W.; Quiros, Antonio J.; Seminerio, Jenifer; Mengesha, Emebet; Alexander, Jonathan S.; Baldassano, Robert N.; Dudley-Brown, Sharon; Cross, Raymond K.; Dassopoulos, Themistocles; Denson, Lee A.; Dhere, Tanvi A.; Iskandar, Heba; Dryden, Gerald W.; Hou, Jason K.; Hussain, Sunny Z.; Hyams, Jeffrey S.; Isaacs, Kim L.; Kader, Howard; Kappelman, Michael D.; Katz, Jeffry; Kellermayer, Richard; Kuemmerle, John F.; Lazarev, Mark; Li, Ellen; Mannon, Peter; Moulton, Dedrick E.; Newberry, Rodney D.; Patel, Ashish S.; Pekow, Joel; Saeed, Shehzad A.; Valentine, John F.; Wang, Ming-Hsi; McCauley, Jacob L.; Abreu, Maria T.; Jester, Traci; Molle-Rios, Zarela; Palle, Sirish; Scherl, Ellen J.; Kwon, John; Rioux, John D.; Duerr, Richard H.; Silverberg, Mark S.; Zwick, Michael E.; Stevens, Christine; Daly, Mark J.; Cho, Judy H.; Gibson, Greg; McGovern, Dermot P. B.; Brant, Steven R.; Kugathasan, Subra Share Save
Transethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals not only shared but also ethnicity-specific disease associations Degenhardt, Frauke; Mayr, Gabriele; Wendorff, Mareike; Boucher, Gabrielle; Ellinghaus, Eva; Ellinghaus, David; ElAbd, Hesham; Rosati, Elisa; Huebenthal, Matthias; Juzenas, Simonas; Abedian, Shifteh; Vahedi, Homayon; Thelma, B. K.; Yang, Suk-Kyun; Ye, Byong Duk; Cheon, Jae Hee; Datta, Lisa Wu; Daryani, Naser Ebrahim; Ellul, Pierre; Esaki, Motohiro; Fuyuno, Yuta; McGovern, Dermot P. B.; Haritunians, Talin; Hong, Myhunghee; Juyal, Garima; Jung, Eun Suk; Kubo, Michiaki; Kugathasan, Subra; Lenz, Tobias L.; Leslie, Stephen; Malekzadeh, Reza; Midha, Vandana; Motyer, Allan; Ng, Siew C.; Okou, David T.; Raychaudhuri, Soumya; Schembri, John; Schreiber, Stefan; Song, Kyuyoung; Sood, Ajit; Takahashi, Atsushi; Torres, Esther A.; Umeno, Junji; Alizadeh, Behrooz Z.; Weersma, Rinse K.; Wong, Sunny H.; Yamazaki, Keiko; Karlsen, Tom H.; Rioux, John D.; Brant, Steven R.; Franke, Andre Share Save
Life-threatening arrhythmias with autosomal recessive TECRL variants Webster, Gregory; Aburawi, Elhadi H.; Chaix, Marie A.; Chandler, Stephanie; Foo, Roger; Islam, A. K. M. Monwarul; Kammeraad, Janneke A. E.; Rioux, John D.; Al-Gazali, Lihadh; Sayeed, Md Zahidus; Xiao, Tingting; Zhang, Han; Xie, Lijian; Hou, Cuilan; Ing, Alexander; Yap, Kai Lee; Wilde, Arthur A. M.; Bhuiyan, Zahurul A. Share Save
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