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T

Timothy F. Cloughesy

David Geffen School of Medicine

128H-index
1.4KPaper Count
6.3WCitation Count
Published Papers 393
Publication Date
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Imaging patterns of necrosis after treatment with chemoradiation are prognostic for survival in glioblastoma
errEuropean Radiology
IF4.7
err2026-09-29
err0
errOAAI
errJohanna Heugenhauser; Francesco Sanvito; Jingwen Yao; Irina Kryukov; Catalina Raymond; Ashley Teraishi; Phioanh L. Nghiemphu; Albert Lai; Robert M. Prins; David A. Nathanson; Timothy F. Cloughesy; Benjamin M. Ellingson
errShare
errSave
Neoadjuvant PD1 plus CTLA-4 immune checkpoint blockade in surgically resectable recurrent glioblastoma: a randomized surgical window-of-opportunity trial
errNature Communications
IF15.7
err2026-09-05
err0
errOAAI
errLu Sun; Lauren F. Markus; Julio C. Sanchez; Thomas J. Lai; Eudocia Quant Lee; Gang Li; Jiyoon Kim; Zian Zhuang; Brenda Acevedo; Richard G. Everson; Ingo K. Mellinghoff; Elisa Aquilanti; L. Nicolas Gonzalez Castro; J. Ricardo McFaline-Figueroa; Lakshmi Nayak; Rameen Beroukhim; Robert A. Chong; Jacqueline Stone; Thomas Kaley; Lauren Schaff; Jessica Wilcox; Catharina Westergaard; Alyssa Russ; Maria Lavallee; Ugonma Chukwueke; Annick D. Van den Abbeele; Michael Lim; Benjamin M. Ellingson; David A. Reardon; Timothy F. Cloughesy; Robert M. Prins; Patrick Y. Wen
errShare
errSave
CTIM-12. DUAL IMMUNE CHECKPOINT BLOCKADE FOR SURGICALLY ACCESSIBLE RECURRENT GLIOBLASTOMA: CLINICAL AND MOLECULAR OUTCOMES
errNeuro-Oncology
IF13.4
err2025-11-11
err0
errOAAI
errLu Sun; Eudocia Quant Lee; Gang Li; David A Reardon; Brenda Acevedo; Catharina Westergaard; Alyssa Russ; Richard G Everson; Benjamin M Ellingson; Ingo K Mellinghoff; Elisa Aquilanti; L Nicolas Gonzalez Castro; J Ricardo McFaline-Figueroa; Lakshmi Nayak; Rameen Beroukhim; Robert A Chong; Jacqueline Stone; Thomas Kaley; Lauren Schaff; Jessica wilcox; Maria Lavallee; Ugonma Chukwueke; Annick D Van den Abbeele; Michael Lim; Timothy F Cloughesy; Robert M Prins; Patrick Y Wen
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errSave
CTNI-53. PATIENTS WITH ISOCITRATE DEHYDROGENASE-MUTANT GLIOMA TREATED WITH VORASIDENIB: UPDATED DATA FROM THE VORASIDENIB EXPANDED ACCESS PROGRAM
errNeuro-Oncology
IF13.4
err2025-11-11
err0
errOAAI
errTimothy F Cloughesy; Katherine B Peters; Howard Colman; Jennie W Taylor; Ingo K Mellinghoff; Helen A Shih; Christelle Chacar; Jonathan Dewey; Patrick Y Wen
errShare
errSave
Multivariate survival risk stratification in GBMs lacking necrosis and microvascular proliferation
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errMolinaro, Annette; McCoy, Lucie; Warrier, Gayathri; Al-Adli, Nadeem; Young, Jacob S.; Mendez, Joe; Malani, Rachna; Hamel, Elaine; Odell, Jennifer Ledbetter; Eldred, Blaine; Nghiemphu, Phioanh; Liau, Linda M.; Ligon, Keith; Reardon, David A.; Lachance, Daniel; Decker, Paul; Eckel-Passow, Jeanette; Burns, Terry; Kosel, Matthew; Ida, Cristiane; Vaubel, Rachael; Giannini, Caterina; Kollmeyer, Thomas; Kizilbash, Sani; Maqbool, Muhammad Asad; Shafqat, Shameel; Mansouri, Alireza; Jenkins, Robert; Cloughesy, Timothy; Lai, Albert; Youssef, Gilbert; Wen, Patrick; Solomon, David; Chang, Susan; de Groot, John; Colman, Howard
errShare
errSave
Volumetric (3D) compared with traditional bidirectional (2D) assessment in patients with Grade 2, isocitrate dehydrogenase 1/2 mutant (mIDH1/2) glioma receiving vorasidenib or placebo in the Phase 3 INDIGO trial
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errEllingson, Benjamin M.; Mellinghoff, Ingo; Van Den Bent, Martin J.; Blumenthal, Deborah T.; Touat, Mehdi; Peters, Katherine B.; Clarke, Jennifer L.; Mendez, Joe; Yust-Katz, Shlomit; Welsh, Liam; Mason, Warren P.; Ducray, Francois; Umemura, Yoshie; Nabors, Burt; Holdhoff, Matthias; Hottinger, Andreas F.; Arakawa, Yoshiki; Sepulveda, Juan M.; Wick, Wolfgang; Soffietti, Riccardo; Perry, James; Giglio, Pierre; De La Fuente, Macarena, I; Maher, Elizabeth; Zhao, Dan; Pandya, Shuchi S.; Steelman, Lori; Hassan, Islam; Wen, Patrick Y.; Cloughesy, Timothy F.
errShare
errSave
GliomaPDOX - A direct brain-to-brain glioma xenograft library for drug discovery and development
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errFernandez, Elizabeth; Tse, Christopher; Salinas, Jennifer; Bayley, Nicholas; Ta, Lisa; Gosa, Laura; Zhu, Henan; Andrasz, Cassidy; Vigman, Michael; Sanvito, Francesco; Ellingson, Benjamin; Liau, Linda; Cloughesy, Timothy; Graeber, Thomas; Nathanson, David
errShare
errSave
PHASE 1B SAFETY RESULTS OF VORASIDENIB IN COMBINATION WITH TEMOZOLOMIDE IN PATIENTS WITH MUTANT IDH1 OR IDH2 GLIOMA
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errde la Fuente, Macarena, I; Cloughesy, Timothy F.; Touat, Mehdi; Lopez, Juanita; McBain, Catherine; Steelman, Lori; Hassan, Islam; Jain, Payal; Man, Albert; Abshire, Michelle; Knipstein, Jeffrey; Mellinghoff, Ingo; Wen, Patrick Y.
errShare
errSave
GBM NEURODEVELOPMENTAL LINEAGE PLASTICITY DRIVES RAPID ADAPTATION TO ONCOGENE TARGETED THERAPY
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errCadet, Dimitri; Harris, Toby; Fazzari, Elisa; Andrasz, Cassidy; Bayley, Nicholas; Graeber, Thomas; Cloughesy, Timothy; Bhaduri, Aparna; Nathanson, David
errShare
errSave
Update on GBM AGILE: A global, phase 2/3 adaptive platform trial to evaluate multiple regimens in newly diagnosed and recurrent glioblastoma
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errLim, Michael; Berry, Donald; Berry, Nicholas; Colman, Howard; De Groot, John; Ellingson, Benjamin; Gan, Hui; Hyddmark, E. Viktoria; Johnson, Adam; Lassman, Andrew; Mellinghoff, Ingo; Perry, James; Sulman, Erik; Weller, Michael; Wen, Patrick; Cloughesy, Timothy; Network, Gbm Agile Trial
errShare
errSave
Volumetric tumor growth rate (TGR) modeling predicts clinical outcomes in patients with Grade 2, isocitrate dehydrogenase 1/2 mutant (mIDH1/2) glioma receiving vorasidenib or placebo in the Phase 3 INDIGO trial
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errEllingson, Benjamin M.; Mellinghoff, Ingo; Van Den Bent, Martin J.; Blumenthal, Deborah T.; Touat, Mehdi; Peters, Katherine B.; Clarke, Jennifer L.; Mendez, Joe; Yust-Katz, Shlomit; Welsh, Liam; Mason, Warren P.; Ducray, Francois; Umemura, Yoshie; Nabors, Burt; Holdhoff, Matthias; Hottinger, Andreas F.; Arakawa, Yoshiki; Sepulveda, Juan M.; Wick, Wolfgang; Soffietti, Riccardo; Perry, James; Giglio, Pierre; De La Fuente, Macarena, I; Maher, Elizabeth; Zhao, Dan; Pandya, Shuchi S.; Steelman, Lori; Hassan, Islam; Wen, Patrick Y.; Cloughesy, Timothy F.
errShare
errSave
Perfusion, diffusion, and anatomical MRI characteristics of pathologically confirmed malignant transformation in IDH-mutant gliomas
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
PREAI
errCho, Nicholas S.; Le, Vien Lam; Teraishi, Ashley; Liu, Vicki; Sanvito, Francesco; Telesca, Donatello; Nakajo, Masanori; Wang, Chencai; Oshima, Sonoko; Eldred, Blaine S. C.; Yao, Jingwen; Nghiemphu, Phioanh L.; Salamon, Noriko; Cloughesy, Timothy F.; Lai, Albert; Ellingson, Benjamin M.
errShare
errSave
INTEGRATED MONITORING OF RNA-SEQUENCING AND COMPLETE BLOOD COUNT PREDICTS IMMUNE RESPONSE AND OUTCOME IN A CLINICAL TRIAL OF DUAL NEOADJUVANT IMMUNE CHECKPOINT BLOCKADE IN GLIOBLASTOMA
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errLai, Thomas; Sun, Lu; Cloughesy, Timothy; Wen, Patrick; Prins, Robert
errShare
errSave
Corticosteroid-induced contrast-enhancing volume shrinkage and apparent diffusion coefficient reduction in glioblastoma MRI
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errSanvito, Francesco; Kim, Asher; Raymond, Catalina; Teraishi, Ashley; Everson, Richard; Nghiemphu, Phioanh; Lai, Albert; Chong, Robert; Nathanson, David; Salamon, Noriko; Cloughesy, Timothy; Yao, Jingwen; Ellingson, Benjamin
errShare
errSave
LIPID METABOLIC HETEROGENEITY ACROSS GLIOMA CELLULAR STATES REVEALS ENVIRONMENTAL DEPENDENCIES
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errBayley, Nicholas; Minami, Jenna; Andrasz, Cassidy; Tse, Christopher; Salinas, Jennifer; Cadet, Dimitri; Bhaduri, Aparna; Cloughesy, Timothy; Graeber, Thomas; Nathanson, David
errShare
errSave
Vorasidenib in IDH1-mutant or IDH2-mutant low-grade glioma (INDIGO): secondary and exploratory endpoints from a randomised, double-blind, placebo-controlled, phase 3 trial
errThe Lancet Oncology
IF0
err2025-10-29
err0
PREAI
errTimothy F Cloughesy; Martin J van den Bent; Mehdi Touat; Deborah T Blumenthal; Katherine B Peters; Benjamin M Ellingson; Jennifer L Clarke; Joe Mendez; Shlomit Yust-Katz; Liam Welsh; Warren P Mason; Francois Ducray; Yoshie Umemura; Burt Nabors; Matthias Holdhoff; Andreas F Hottinger; Yoshiki Arakawa; Juan M Sepulveda; Wolfgang Wick; Riccardo Soffietti; James Perry; Pierre Giglio; Macarena de la Fuente; Elizabeth Maher; Andrew Bottomley; Adriana E Tron; Denise Yi; Dan Zhao; Shuchi S Pandya; Lori Steelman; Islam Hassan; Patrick Y Wen; Ingo K Mellinghoff
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errSave
EARLY TUMOR VOLUME CHANGES PREDICT CLINICAL OUTCOMES IN MIDH1/2 GLIOMA: POST-HOC RESULTS FROM THE PHASE 3 INDIGO TRIAL
errNEURO-ONCOLOGY
IF13.4
err2025-10-01
err0
errOAAI
errEllingson, B. M.; Mellinghoff, I. K.; van den Bent, M. J.; Blumenthal, D. T.; Touat, M.; Peters, K. B.; Clarke, J. L.; Mendez, J.; Yust-Katz, S.; Welsh, L.; Mason, W. P.; Ducray, F.; Umemura, Y.; Nabors, B.; Holdhoff, M.; Hottinger, A. F.; Arakawa, Y.; Sepulveda, J. M.; Wick, W.; Soffietti, R.; Perry, J.; Giglio, P.; de la Fuente, M.; Maher, E.; Zhao, D.; Pandya, S. S.; Steelman, L.; Hassan, I; Wen, P. Y.; Cloughesy, T. F.
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errSave
EXPLORATORY ANALYSES FROM PHASE 3 INDIGO STUDY SUGGEST POTENTIAL MECHANISM OF SEIZURE CONTROL THROUGH TUMOR VOLUME REDUCTION UNDER TREATMENT WITH VORASIDENIB
errNEURO-ONCOLOGY
IF13.4
err2025-10-01
err0
errOAAI
errWick, W.; Mellinghoff, I. K.; van den Bent, M. J.; Blumenthal, D. T.; Touat, M.; Peters, K. B.; Clarke, J. L.; Mendez, J.; Welsh, L.; Mason, W. P.; Hottinger, A. F.; Sepulveda, J. M.; Soffietti, R.; Zhao, D.; Yi, D.; Weidl, D.; Steelman, L.; Hassan, I; Wen, P. Y.; Cloughesy, T. F.
errShare
errSave
ASSOCIATION OF PROTON PUMP INHIBITOR USE WITH OUTCOME OF PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA
errNEURO-ONCOLOGY
IF13.4
err2025-10-01
err0
errOAAI
errLe Rhun, E.; Sain, D.; Sara, E. C.; Reardon, D. A.; Minniti, G.; Roth, P.; Wick, W.; Nabors, B.; Sampson, J.; Mason, W.; Cloughesy, T.; Reijneveld, J. C.; Stupp, R.; Preusser, M.; Gorlia, T.; Weller, M.
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errSave
Phase Ib/II Study of Pamiparib Plus Radiation Therapy and/or Temozolomide in Adult Patients with Treatment-Naïve or Recurrent/Refractory Glioblastoma
errCurrent Oncology 2025, Vol. 32, Page 541
IF0
err2025-09-29
err0
errOAAI
errAnna F. Piotrowski; Kent Shih; Pierre Giglio; Howard Colman; Patrick Y. Wen; Jian Li Campian; Nicholas Butowski; Timothy Cloughesy; Zhaoyin Zhu; Vitaliy Gisin; Michael Badruddoja
errShare
errSave

Research Directions

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