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Moira K. B. Whyte

University of Edinburgh
H-index:74
Citation Count:2.1万
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Author Correction: Hypoxia induces histone clipping and H3K4me3 loss in neutrophil progenitors resulting in long-term impairment of neutrophil immunity

作者更正：缺氧诱导中性粒细胞前体细胞发生组蛋白剪切和H3K4me3丢失，从而导致中性粒细胞免疫的长期损害。

Nature Immunology
IF27.6
2025-12-010
OAAI
Manuel A. Sanchez-Garcia; Pranvera Sadiku; Brian M. Ortmann; Niek Wit; Yutaka Negishi; Patricia Coelho; Ailiang Zhang; Chinmayi Pednekar; Andrew J. M. Howden; David M. Griffith; Rachel Seear; Jessica D. Kindrick; Janine Mengede; George Cooper; Tyler Morrison; Emily R. Watts; Benjamin T. Shimeld; Leila Reyes; Ananda S. Mirchandani; Simone Arienti; Xiang Xu; Alexander Thomson; Alejandro J. Brenes; Helena A. Turton; Rebecca Dowey; Rebecca C. Hull; Hazel Davidson-Smith; Amy McLaren; Andrew Deans; Gourab Choudhury; Katherine Doverman; David Hope; Oliver Vick; Alastair Woodhead; Isla Petrie; Suzanne Green; Nina M. Rzechorzek; Lance Turtle; Peter J. M. Openshaw; Malcolm G. Semple; Duncan Sproul; J. Kenneth Baillie; Alfred A. R. Thompson; David R. Mole; Alex von Kriegsheim; Moira K. B. Whyte; Musa M. Mhlanga; James A. Nathan; Sarah R. Walmsley
Hypoxia induces histone clipping and H3K4me3 loss in neutrophil progenitors resulting in long-term impairment of neutrophil immunity

缺氧诱导中性粒细胞前体细胞发生组蛋白剪切和H3K4me3丢失，从而导致中性粒细胞免疫功能的长期损害。

Nature Immunology
IF27.6
2025-10-280
OAAI
Manuel A. Sanchez-Garcia; Pranvera Sadiku; Brian M. Ortmann; Niek Wit; Yutaka Negishi; Patricia Coelho; Ailiang Zhang; Chinmayi Pednekar; Andrew J. M. Howden; David M. Griffith; Rachel Seear; Jessica D. Kindrick; Janine Mengede; George Cooper; Tyler Morrison; Emily R. Watts; Benjamin T. Shimeld; Leila Reyes; Ananda S. Mirchandani; Simone Arienti; Xiang Xu; Alexander Thomson; Alejandro J. Brenes; Helena A. Turton; Rebecca Dowey; Rebecca C. Hull; Hazel Davidson-Smith; Amy McLaren; Andrew Deans; Gourab Choudhury; Katherine Doverman; David Hope; Oliver Vick; Alastair Woodhead; Isla Petrie; Suzanne Green; Nina M. Rzechorzek; Lance Turtle; Peter J. M. Openshaw; Malcolm G. Semple; Duncan Sproul; J. Kenneth Baillie; Alfred A. R. Thompson; David R. Mole; Alex von Kriegsheim; Moira K. B. Whyte; Musa M. Mhalanga; James A. Nathan; Sarah R. Walmsley
Neutrophil extracellular traps are associated with airways inflammation and increased severity of lung disease in cystic fibrosis

中性粒细胞胞外陷阱与囊性纤维化患者的气道炎症及肺部疾病严重程度的增加相关。

ERJ OPEN RESEARCH
IF4
2024-07-181
OA
Law, Sheonagh M.; Hardisty, Gareth; Gillan, Jonathan L.; Robinson, Nicola J.; Davidson, Donald J.; Whyte, Moira K. B.; Dransfield, Ian; Gray, Robert D.
PCSK6 and Survival in Idiopathic Pulmonary Fibrosis
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
IF19.4
2023-06-0115
OAAI
Oldham, Justin M.; Allen, Richard J.; Lorenzo-Salazar, Jose M.; Molyneaux, Philip L.; Ma, Shwu-Fan; Joseph, Chitra; Kim, John S.; Guillen-Guio, Beatriz; Hernandez-Beeftink, Tamara; Kropski, Jonathan A.; Huang, Yong; Lee, Cathryn T.; Adegunsoye, Ayodeji; Pugashetti, Janelle Vu; Linderholm, Angela L.; Vo, Vivian; Strek, Mary E.; Jou, Jonathan; Munoz-Barrera, Adrian; Rubio-Rodriguez, Luis A.; Hubbard, Richard; Hirani, Nik; Whyte, Moira K. B.; Hart, Simon; Nicholson, Andrew G.; Lancaster, Lisa; Parfrey, Helen; Rassl, Doris; Wallace, William; Valenzi, Eleanor; Zhang, Yingze; Mychaleckyj, Josyf; Stockwell, Amy; Kaminski, Naftali; Wolters, Paul J.; Molina-Molina, Maria; Banovich, Nicholas E.; Fahy, William A.; Martinez, Fernando J.; Hall, Ian P.; Tobin, Martin D.; Maher, Toby M.; Blackwell, Timothy S.; Yaspan, Brian L.; Jenkins, R. Gisli; Flores, Carlos; Wain, Louise V.; Noth, Imre
CAGE sequencing reveals CFTR-dependent dysregulation of type I IFN signaling in activated cystic fibrosis macrophages
SCIENCE ADVANCES
IF12.5
2023-05-266
OAAI
Gillan, Jonathan L.; Chokshi, Mithil; Hardisty, Gareth R.; Hendry, Sara Clohisey; Prasca-Chamorro, Daniel; Robinson, Nicola J.; Lasota, Benjamin; Clark, Richard; Murphy, Lee; Whyte, Moira K. B.; Baillie, J. Kenneth; Davidson, Donald J.; Bao, Gang; Gray, Robert D.
NRF2 Activation Reprograms Defects in Oxidative Metabolism to Restore Macrophage Function in Chronic Obstructive Pulmonary Disease
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
IF19.4
2023-04-1530
OAAI
Ryan, Eilise M.; Sadiku, Pranvera; Coelho, Patricia; Watts, Emily R.; Zhang, Ailiang; Howden, Andrew J. M.; Sanchez-Garcia, Manuel A.; Bewley, Martin; Cole, Joby; McHugh, Brian J.; Vermaelen, Wesley; Ghesquiere, Bart; Carmeliet, Peter; Blanco, Giovanny Rodriguez; Von Kriegsheim, Alex; Sanchez, Yolanda; Rumsey, William; Callahan, James F.; Cooper, George; Parkinson, Nicholas; Baillie, Kenneth; Cantrell, Doreen A.; McCafferty, John; Choudhury, Gourab; Singh, Dave; Dockrell, David H.; Whyte, Moira K. B.; Walmsley, Sarah R.
Longitudinal lung function and gas transfer in individuals with idiopathic pulmonary fibrosis: a genome-wide association study
LANCET RESPIRATORY MEDICINE
IF32.8
2023-01-0129
OAAI
Allen, Richard J.; Oldham, Justin M.; Jenkins, David A.; Leavy, Olivia C.; Guillen-Guio, Beatriz; Melbourne, Carl A.; Ma, Shwu-Fan; Jou, Jonathan; Kim, John S.; Fahy, William A.; Oballa, Eunice; Hubbard, Richard B.; Navaratnam, Vidya; Braybrooke, Rebecca; Saini, Gauri; Roach, Katy M.; Tobin, Martin D.; Hirani, Nik; Whyte, Moira K. B.; Kaminski, Naftali; Zhang, Yingze; Martinez, Fernando J.; Linderholm, Angela L.; Adegunsoye, Ayodeji; Strek, Mary E.; Maher, Toby M.; Molyneaux, Philip L.; Flores, Carlos; Noth, Imre; Jenkins, R. Gisli; Wain, Louise, V
Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation (vol 23, pg 927, 2022)
NATURE IMMUNOLOGY
IF27.6
2022-07-190
OAAI
Mirchandani, Ananda S.; Jenkins, Stephen J.; Bain, Calum C.; Sanchez-Garcia, Manuel A.; Lawson, Hannah; Coelho, Patricia; Murphy, Fiona; Griffith, David M.; Zhang, Ailiang; Morrison, Tyler; Ly, Tony; Arienti, Simone; Sadiku, Pranvera; Watts, Emily R.; Dickinson, Rebecca. S.; Reyes, Leila; Cooper, George; Clark, Sarah; Lewis, David; Kelly, Van; Spanos, Christos; Musgrave, Kathryn M.; Delaney, Liam; Harper, Isla; Scott, Jonathan; Parkinson, Nicholas J.; Rostron, Anthony J.; Baillie, J. Kenneth; Clohisey, Sara; Pridans, Clare; Campana, Lara; Lewis, Philip Starkey; Simpson, A. John; Dockrell, David H.; Schwarze, Juergen; Hirani, Nikhil; Ratcliffe, Peter J.; Pugh, Christopher W.; Kranc, Kamil; Forbes, Stuart J.; Whyte, Moira K. B.; Walmsley, Sarah R.
Pannexin 1 drives efficient epithelial repair after tissue injury
SCIENCE IMMUNOLOGY
IF16.3
2022-05-2712
OAAI
Lucas, Christopher D.; Medina, Christopher B.; Bruton, Finnius A.; Dorward, David A.; Raymond, Michael H.; Tufan, Turan; Etchegaray, J. Iker; Barron, Brady; Oremek, Magdalena E. M.; Arandjelovic, Sanja; Farber, Emily; Onngut-Gumuscu, Suna; Ke, Eugene; Whyte, Moira K. B.; Rossi, Adriano G.; Ravichandran, Kodi S.
Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation
NATURE IMMUNOLOGY
IF27.6
2022-05-2735
OAAI
Mirchandani, Ananda S.; Jenkins, Stephen J.; Bain, Calum C.; Sanchez-Garcia, Manuel A.; Lawson, Hannah; Coelho, Patricia; Murphy, Fiona; Griffith, David M.; Zhang, Ailiang; Morrison, Tyler; Ly, Tony; Arienti, Simone; Sadiku, Pranvera; Watts, Emily R.; Dickinson, Rebecca S.; Reyes, Leila; Cooper, George; Clark, Sarah; Lewis, David; Kelly, Van; Spanos, Christos; Musgrave, Kathryn M.; Delaney, Liam; Harper, Isla; Scott, Jonathan; Parkinson, Nicholas J.; Rostron, Anthony J.; Baillie, J. Kenneth; Clohisey, Sara; Pridans, Clare; Campana, Lara; Lewis, Philip Starkey; Simpson, A. John; Dockrell, David H.; Schwarze, Jurgen; Hirani, Nikhil; Ratcliffe, Peter J.; Pugh, Christopher W.; Kranc, Kamil; Forbes, Stuart J.; Whyte, Moira K. B.; Walmsley, Sarah R.
Psychometric properties of patient reported outcome measures in idiopathic pulmonary fibrosis
CHRONIC RESPIRATORY DISEASE
IF2.3
2021-10-0517
OAAI
Kim, Jee Whang; Clark, Allan; Birring, Surinder S.; Atkins, Christopher; Whyte, Moira; Wilson, Andrew M.
Hypoxia drives murine neutrophil protein scavenging to maintain central carbon metabolism
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2021-05-1721
OA
Watts, Emily R.; Howden, Andrew J. M.; Morrison, Tyler; Sadiku, Pranvera; Hukelmann, Jens; von Kriegsheim, Alex; Ghesquiere, Bart; Murphy, Fiona; Mirchandani, Ananda S.; Humphries, Duncan C.; Grecian, Robert; Ryan, Eilise M.; Coelho, Patricia; Blanco, Gio Rodriguez; Plant, Tracie M.; Dickinson, Rebecca S.; Finch, Andy; Vermaelen, Wesley; Cantrell, Doreen A.; Whyte, Moira K.; Walmsley, Sarah R.
Securing a sustainable and fit-for-purpose UK health and care workforce

确保可持续和适合目的的英国卫生和护理人员

LANCET
IF88.5
2021-05-0178
OAAI
Anderson, Michael; O'Neill, Ciaran; Clark, Jill Macleod; Street, Andrew; Woods, Michael; Johnston-Webber, Charlotte; Charlesworth, Anita; Whyte, Moira; Foster, Margaret; Majeed, Azeem; Pitchforth, Emma; Mossialos, Elias; Asaria, Miqdad; McGuire, Alistair
LSE-Lancet Commission on the future of the NHS: re-laying the foundations for an equitable and efficient health and care service after COVID-19
LANCET
IF88.5
2021-05-0155
OAAI
Anderson, Michael; Pitchforth, Emma; Asaria, Miqdad; Brayne, Carol; Casadei, Barbara; Charlesworth, Anita; Coulter, Angela; Franklin, Bryony Dean; Donaldson, Cam; Drummond, Michael; Dunnell, Karen; Foster, Margaret; Hussey, Ruth; Johnson, Paul; Johnston-Webber, Charlotte; Knapp, Martin; Lavery, Gavin; Longley, Marcus; Clark, Jill Macleod; Majeed, Azeem; McKee, Martin; Newton, John N.; O'Neill, Ciaran; Raine, Rosalind; Richards, Mike; Sheikh, Aziz; Smith, Peter; Street, Andrew; Taylor, David; Watt, Richard G.; Whyte, Moira; Woods, Michael; McGuire, Alistair; Mossialos, Elias
Neutrophils Fuel Effective Immune Responses through Gluconeogenesis and Glycogenesis
CELL METABOLISM
IF30.9
2021-02-01118
OAAI
Sadiku, Pranvera; Willson, Joseph A.; Ryan, Ellise M.; Sammut, David; Coelho, Patricia; Watts, Emily R.; Grecian, Robert; Young, Jason M.; Bewley, Martin; Arienti, Simone; Mirchandani, Ananda S.; Garcia, Manuel A. Sanchez; Morrison, Tyler; Zhang, Ailing; Reyes, Leila; Griessler, Tobias; Jheeta, Privjyot; Paterson, Gordon G.; Graham, Christopher J.; Thomson, John P.; Baillie, Kenneth; Thompson, A. A. Roger; Morgan, Jessie-May; Acosta-Sanchez, Abel; Darde, Veronica M.; Duran, Jordi; Guinovart, Joan J.; Rodriguez-Blanco, Gio; Von Kriegsheim, Alex; Meehan, Richard R.; Mazzone, Massimiliano; Dockrell, David H.; Ghesquiere, Bart; Carmeliet, Peter; Whyte, Moira K. B.; Walmsley, Sarah R.
THE NSCLC PLEURAL METASTATIC ENVIRONMENT INFLUENCES THE ROLE NEUTROPHILS PLAY IN THE IMMUNE CHECKPOINT
THORAX
IF7.7
2021-01-210
PRE
Grecian, R.; Findlay, E. Gwyer; Dhaliwal, K.; Byron, A.; Frame, M.; Whyte, M.; Walmsley, S.
Effect of Co-trimoxazole (Trimethoprim-Sulfamethoxazole) vs Placebo on Death, Lung Transplant, or Hospital Admission in Patients With Moderate and Severe Idiopathic Pulmonary Fibrosis The EME-TIPAC Randomized Clinical Trial
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
IF55
2020-12-0839
OA
Wilson, Andrew M.; Clark, Allan B.; Cahn, Tony; Chilvers, Edwin R.; Fraser, William; Hammond, Matthew; Livermore, David M.; Maher, Toby M.; Parfrey, Helen; Swart, Ann Marie; Stirling, Susan; Thickett, David R.; Whyte, Moira
Semaphorin 3F signaling actively retains neutrophils at sites of inflammation
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2020-05-1815
OAAI
Plant, Tracie; Eamsamarng, Suttida; Sanchez-Garcia, Manuel A.; Reyes, Leila; Renshaw, Stephen A.; Coelho, Patricia; Mirchandani, Ananda S.; Morgan, Jessie-May; Ellett, Felix E.; Morrison, Tyler; Humphries, Duncan; Watts, Emily R.; Murphy, Fiona; Raffo-Iraolagoitia, Ximena L.; Zhang, Ailiang; Cash, Jenna L.; Loynes, Catherine; Elks, Philip M.; Van Eeden, Freek; Carlin, Leo M.; Furley, Andrew J. W.; Whyte, Moira K. B.; Walmsley, Sarah R.
Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
IF19.4
2020-03-01196
OAAI
Allen, Richard J.; Guillen-Guio, Beatriz; Oldham, Justin M.; Ma, Shwu-Fan; Dressen, Amy; Paynton, Megan L.; Kraven, Luke M.; Obeidat, Ma'en; Li, Xuan; Ng, Michael; Braybrooke, Rebecca; Molina-Molina, Maria; Hobbs, Brian D.; Putman, Rachel K.; Sakornsakolpat, Phuwanat; Booth, Helen L.; Fahy, William A.; Hart, Simon P.; Hill, Mike R.; Hirani, Nik; Hubbard, Richard B.; McAnulty, Robin J.; Millar, Ann B.; Navaratnam, Vidyia; Oballa, Eunice; Parfrey, Helen; Saini, Gauri; Whyte, Moira K. B.; Zhang, Yingze; Kaminski, Naftali; Adegunsoye, Ayodeji; Strek, Mary E.; Neighbors, Margaret; Sheng, Xuting R.; Gudmundsson, Gunnar; Gudnason, Vilmundur; Hatabu, Hiroto; Lederer, David J.; Manichaikul, Ani; Newell, John D., Jr.; O'Connor, George T.; Ortega, Victor E.; Xu, Hanfei; Fingerlin, Tasha E.; Bosse, Yohan; Hao, Ke; Joubert, Philippe; Nickle, David C.; Sin, Don D.; Timens, Wim; Furniss, Dominic; Morris, Andrew P.; Zondervan, Krina T.; Hall, Ian P.; Sayers, Ian; Tobin, Martin D.; Maher, Toby M.; Cho, Michael H.; Hunninghake, Gary M.; Schwartz, David A.; Yaspan, Brian L.; Molyneaux, Philip L.; Flores, Carlos; Noth, Imre; Jenkins, R. Gisli; Wain, Louise, V
A therapeutic antibody targeting osteoprotegerin attenuates severe experimental pulmonary arterial hypertension

靶向骨保护素的治疗性抗体可减轻严重的实验性肺动脉高压

NATURE COMMUNICATIONS
IF15.7
2019-11-1522
OAAI
Arnold, Nadine D.; Pickworth, Josephine A.; West, Laura E.; Dawson, Sarah; Carvalho, Joana A.; Casbolt, Helen; Braithwaite, Adam T.; Iremonger, James; Renshall, Lewis; Germaschewski, Volker; McCourt, Matthew; Bland-Ward, Philip; Kowash, Hager; Hameed, Abdul G.; Rothman, Alexander M. K.; Frid, Maria G.; Thompson, A. A. Roger; Evans, Holly R.; Southwood, Mark; Morrell, Nicholas W.; Crossman, David C.; Whyte, Moira K. B.; Stenmark, Kurt R.; Newman, Christopher M.; Kiely, David G.; Francis, Sheila E.; Lawrie, Allan

Research Directions

The data has not been retrieved yet.
D
David H. Dockrell
H-index:67Papers:292Citations:1.3万
I
Ian Sabroe
H-index:61Papers:265Citations:1.0万
S
Sarah R. Walmsley
H-index:42Papers:113Citations:9,835
H
Helen M. Marriott
H-index:36Papers:81Citations:4,717
S
Stephen A. Renshaw
H-index:57Papers:212Citations:1.1万
L
Lynne R. Prince
H-index:26Papers:56Citations:2,859
M
Martin A. Bewley
H-index:18Papers:41Citations:1,361
A
A. A. Roger Thompson
H-index:45Papers:225Citations:1.0万
E
Emily Watts
H-index:15Papers:59Citations:1,194
P
Pranvera Sadiku
H-index:16Papers:36Citations:1,170