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Shuofeng Yuan

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49H-index
233Paper Count
2.6WCitation Count
Published Papers 123
Publication Date
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CSDE1 promotes viral immune evasion through RNA-dependent and phosphorylation-modulated liquid-liquid phase separation
errNature Communications
IF15.7
err2026-04-28
err0
errOAAI
errYi Zheng; Xuejing Zhang; Jinxiu Hou; Qian Guo; Zhenzhi Qin; Huiyu Yang; Xianghe Zhao; Panpan Zhou; Shuofeng Yuan; Chengjiang Gao
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Intranasal administration of broad-spectrum macrocyclic peptide inhibitor protects against SARS-CoV-2 Omicron variants
errNature Communications
IF15.7
err2026-01-26
err0
errOAAI
errMin Wang; Jinyue Yang; Yahong Tan; Shuofeng Yuan; Guoli Shi; Qi Peng; Yongqi Li; Vincent Kwok-Man Poon; Chris Chung-Sing Chan; Na Xiao; Anna Jinxia Zhang; Yubin Xie; Junhua Li; Hao Luo; Yaning Fu; Yong Chen; Alex A. Compton; Youming Zhang; Yang Yang; George Fu Gao; Hongwei Hou; Jasper Fuk-Woo Chan; Yizhen Yin; Yi Shi
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Author Correction: An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo
errNature Communications
IF15.7
err2025-12-15
err0
errOAAI
errHuiping Shuai; Jingxin Qiao; Chaemin Yoon; Guo Zhang; Yuxin Hou; Xiaoyan Xia; Lei Wang; Xinyue Deng; Yifei Wang; Qingquan Li; Lianzhao Du; Yuanchen Liu; Minmin Zhou; Hoi Ting Wong; Jiaheng Hu; Huan Liu; Bingjie Hu; Dong Wang; Jingyi Su; Yuying Pan; Yongtao Ye; Yan Chen; Zhen Fang; Ziyi Xia; Yue Chai; Jialu Shi; Yang Wang; Tianrenzheng Zhu; Honglei Zhang; Shuofeng Yuan; Jie Zhou; Jasper Fuk-Woo Chan; Kwok-Yung Yuen; Chunfu Xu; Jian Lei; Shengyong Yang; Hin Chu
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Pathogenicity, virological features, and immune evasion of SARS-CoV-2 JN.1-derived variants including JN.1.7, KP.2, KP.3, and KP.3.1.1
errNature Communications
IF15.7
err2025-12-11
err0
errOAAI
errJialu Shi; Xiaoyu Zhao; Xiaohui Jin; Jiayan Li; Yuanchen Liu; Huan Liu; Ye-Fan Hu; Zhe Chen; Yuxin Xiao; Lei Wang; Yajie Wang; Yixin He; Yue Chai; Bingjie Hu; Huiping Shuai; Yang Wang; Xiangnan Li; Shujun Jiang; Yanliang Zhang; Xiaojuan Zhang; Wan-Mui Chan; Lin-Lei Chen; Jian-Piao Cai; Baokun Sui; Honglei Zhang; Dong Yang; Longchao Zhu; Shuofeng Yuan; Jie Zhou; Jian-Dong Huang; Kwok-Yung Yuen; Kelvin Kai-Wang To; Jasper Fuk-Woo Chan; Bao-Zhong Zhang; Qiao Wang; Maozhou He; Lei Sun; Pengfei Wang; Hin Chu
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Development of monoclonal antibodies against E1 protein of Chikungunya virus
errPLOS NEGLECTED TROPICAL DISEASES
IF3.4
err2025-12-05
err0
PREAI
errWen, Kun; Zhou, Zhihong; Xu, Peipei; Di, Biao; Song, Jialing; Yang, Cuilian; Zhan, Lili; Zhao, Chongquan; Xu, Mei; Cai, Jianpiao; Yuan, Shuofeng; To, Kelvin Kai-Wang; Feng, Wenxi; Chan, Jasper Fuk-Woo; Zhou, Hongwei; Chen, Yue; Ding, Xixia
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Structure-guided discovery of a small molecule inhibitor of SARS-CoV-2 main protease with potent in vitro and in vivo antiviral activities
errJOURNAL OF VIROLOGY
IF3.8
err2025-11-01
err0
PREAI
errYuan, Shuofeng; Wang, Juan; Sang, Xiaohong; Xie, Yubin; Feng, Yong; Poon, Vincent Kwok-Man; Chan, Chris Chung-Sing; Tsang, Jessica Oi-Ling; Chik, Kenn Ka-Heng; Zhou, Jiao; Xu, Yan; Han, Pu; Zheng, Wenyan; Fu, Lifeng; Huang, Lina Sirui Mihara; Wu, Meixian; An, Jing; Yuen, Kwok-Yung; Qi, Jianxun; Huang, Ziwei; Chan, Jasper Fuk-Woo
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errSave
iMeta Conference 2025: Creating high-impact international journals
erriMeta
IF33.2
err2025-10-15
err0
errOAAI
errZhihao Zhu; Lin Zhang; Xiaofang Yao; Meiyin Zeng; Yao Wang; Hao Luo; Yuanping Zhou; Tianyuan Zhang; Jiani Xun; Defeng Bai; Haifei Yang; Shanshan Xu; Yang Zhou; Yunyun Gao; Jinbo Xu; Wei Han; ZiAng Shen; Bangzhou Zhang; Tengfei Ma; Xiu-Lin Wan; Chuang Ma; Fengjiao Hui; Hao Bai; Lijing Bai; Qing Bai; Qiangguo Bao; Guodong Cao; Peng Cao; Qiqi Cao; Hu Chen; Jiawen Chen; Jiaxu Chen; Lihua Chen; Tingting Chen; Yi Chen; Haipeng Cui; Shaoxing Dai; Xi-Jian Dai; Xiaofeng Dai; Yanqi Dang; Lei Deng; Yun Deng; Xia Ding; Binhua Dong; Ling Dong; Shujie Dou; Hongzhi Du; Zhencheng Fang; Xiaoxiao Feng; Min Fu; Yuan Gao; Wenping Gong; Xiang Guo; Wenjie Han; Zikai Hao; Zheng-Guo He; Haibo Hu; Haiming Hu; Xuefei Hu; Liang Huang; Xianya Huang; Xueting Huang; Haochen Hui; Dingjiacheng Jia; Aimin Jiang; Di Jiang; Kun Jiang; Dewei Jiang; Ying Jin; Kunyang Lai; Chun Li; Feng Li; Fuyong Li; Jing Li; Juan Li; Junling Li; Kui Li; Ling Li; Moli Li; Peiwu Li; Peng Li; Runze Li; Shengnan Li; Shujin Li; Wanting Li; Wenting Li; Xiaojing Li; Xinrui Li; Xuemeng Li; Qiqi Liang; Xiaoping Liao; Boyang Liu; Canzhao Liu; Chang Liu; Duanrui Liu; Furong Liu; Jianjun Liu; Jinyao Liu; Siqi Liu; Tianyang Liu; Wenjuan Liu; Yan Liu; Yang Liu; Yi Liu; Yuan Liu; Yunhuan Liu; Zhipeng Liu; Zhiyong Liu; Xin Lu; Xiao Luo; Guanju Ma; Jialin Meng; Yuanfa Meng; Runyu Miao; Linxuan Miao; Yawen Ni; Dongze Niu; Tingting Niu; Hongzhao Pan; Guoqiang Qin; Tiantian Qiu; Yueping Qiu; Hui Qu; Linghang Qu; Na Ren; Qiang Sun; Run Shang; Peize She; Xihui Shen; Bohan Shi; You Shu; Jiawei Song; Weibin Song; Qi Su; Qingzhu Sun; YuPing Sun; Zijin Sun; Bufu Tang; Deqin Tang; Hua Tang; Yongfu Tao; Teng Teng; Yanye Tu; Cheng Wang; Hui Wang; Yunhao Wang; Chunli Wang; Dingjie Wang; Gang Wang; Jin Wang; Kaiyi Wang; Mingbang Wang; Shan Wang; Shixiang Wang; Xiaojie Wang; Xing-Chang Wang; Yunzhe Wang; Jiale Wang; Zheng Wang; Weijie Wang; Yongjun Wei; Wei Xu; Fan Wu; Junling Wu; Shijuan Wu; Jian Xiao; Weihua Xiao; Yang Xiao; Xi Xiong; Xue Xiong; Feng Xu; Junyu Xu; Wen Xu; Jun Xu; Yao Xu; Jun Yan; Lutian Yao; Jia Yang; Lulu Yang; Xingzhen Yang; Naiyi Yin; Hua You; Min You; Ting Yu; Yongyao Yu; Renqiang Yu; Shuofeng Yuan; Chaoxiong Yue; Xiaoya Zeng; Andong Zha; Leilei Zhai; Chi Zhang; Dong Zhang; Hengguo Zhang; Heng Zhang; Hongyu Zhang; Jiahao Zhang; Jinyang Zhang; Lishan Zhang; Qi Zhang; Xiang Zhang; Xiangyu Zhang; Xuelei Zhang; Yancong Zhang; Yuan Zhang; Zhenyu Zhang; Jiwei Zhao; Jingxuan Zhao; Kai Zhao; Mingjuan Zhao; Yi Zhao; Yunxiang Zhao; Jixin Zhong; Ling Zhong; Xiangjian Zhong; Dan Zhou; Wei Zhou; Wen Zhou; Yiqian Zhou; Zhemin Zhou; Shiquan Zhu; Shuang-Jiang Liu; Suyin Feng; Shuangxia Jin; Chuanxing Xiao; Ziheng Wang; Peng Luo; Tong Chen; Gang Chen; Yong-Xin Liu
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Nasal mucus-derived KLK13 restricts SARS-CoV-2 infection via proteolytic cleavage of spike
errMBIO
IF4.7
err2025-10-01
err0
PREAI
errCao, Wenying; Zheng, Ningze; Cao, Hehe; Chen, Ran; Chen, Jianheng; Deng, Xueyi; Zhang, Hui; Yuan, Shuofeng; Zhang, Guigen
errShare
errSave
The microbiome in cancer
erriMeta
IF33.2
err2025-08-30
err0
errOAAI
errAnqi Lin; Minying Xiong; Aimin Jiang; Lihaoyun Huang; Hank Z. H. Wong; Suyin Feng; Chunyan Zhang; Yu Li; Li Chen; Hao Chi; Pengpeng Zhang; Bicheng Ye; Hengguo Zhang; Nan Zhang; Lingxuan Zhu; Weiming Mou; Junyi Shen; Kailai Li; Wentao Xu; Haoxuan Ying; Cangang Zhang; Dongqiang Zeng; Jindong Xie; Xinpei Deng; Qi Wang; Jianying Xu; Wenjie Shi; Chang Qi; Chunrun Qu; Xufeng Huang; András Hajdu; Chaoqun Li; Changmin Peng; Xuanye Cao; Guangsheng Pei; Lin Zhang; Yujia Huo; Jiabao Xu; Antonino Glaviano; Attila Gábor Szöllősi; Sicheng Bian; Zhengrui Li; Hailin Tang; Bufu Tang; Zaoqu Liu; Jian Zhang; Kai Miao; Quan Cheng; Ting Wei; Shuofeng Yuan; Peng Luo
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errSave
SMCseeker: An attentive virtual screening model for antiviral discovery
erriScience
IF4.1
err2025-08-26
err0
errOAAI
errJing Li; Haoran Sun; Xiaoyang Shu; Min Guo; Yubin Xie; Kexin Li; Xiaoyi Guo; Yu Fu; Xing-Yi Ge; Ziyao Zhou; Peng Luo; Kwok-Yung Yuen; You-Qiang Song; Shuofeng Yuan
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errSave
Protein Spatial Structure Meets Artificial Intelligence: Revolutionizing Drug Synergy–Antagonism in Precision Medicine
errAdvanced Science
IF14.1
err2025-08-07
err0
errOAAI
errAnqi Lin; Chang Che; Aimin Jiang; Chang Qi; Antonino Glaviano; Zhijie Zhao; Zhirou Zhang; Zaoqu Liu; Ziyao Zhou; Quan Cheng; Shuofeng Yuan; Peng Luo
errShare
errSave
Broad neuraminidase antibodies confer protection against seasonal and avian influenza viruses
errNature Communications
IF15.7
err2025-08-02
err0
errOAAI
errKexin Lv; Xiaoman Li; Xingchen Zhu; Jian-Piao Cai; Shuning Liu; Yuzhu Sun; Lin Liu; Xiaoyu Cai; Rui Cao; Mengxin Xu; Xinyu Yue; Yanmei Zhai; Wanyu Luo; Hongjie Lu; Ruiying Li; Haoting Mai; Lei Deng; Feng Ye; Shifeng Chen; Mang Shi; Huanle Luo; Xinquan Wang; Shuofeng Yuan; Yuelong Shu; Jiwan Ge; Yao-Qing Chen
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errSave
The P132H mutation of SARS-CoV-2 NSP5 relieves its inhibition on interferon-β activation via blocking MAVS degradation
errCellular and Molecular Life Sciences
IF6.2
err2025-07-30
err0
errOAAI
errYuxin Zhang; Tong-Yun Wang; Huihui Yan; Zhoule Guo; Zhonghao Lian; Hailan Yao; Shuofeng Yuan; Xing-Yi Ge; Ye Qiu
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errSave
Neural mechanisms and clinical features of anti-influenza drug-related psychiatric adverse events
errVIEW
IF8.5
err2025-07-25
err0
errOAAI
errAnqi Lin; Tong Jiang; Chaofan Fan; Yihan Gao; Dan Shan; Qingxi Zhang; Kun Huang; Peng Luo; Shuofeng Yuan; Xin Chen
errShare
errSave
An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo
errNature Communications
IF15.7
err2025-07-16
err0
errOAAI
errHuiping Shuai; Jingxin Qiao; Chaemin Yoon; Guo Zhang; Yuxin Hou; Xiaoyan Xia; Lei Wang; Xinyue Deng; Yifei Wang; Qingquan Li; Lianzhao Du; Yuanchen Liu; Minmin Zhou; Hoi Ting Wong; Jiaheng Hu; Huan Liu; Bingjie Hu; Dong Wang; Jingyi Su; Yuying Pan; Yongtao Ye; Yan Chen; Zhen Fang; Ziyi Xia; Yue Chai; Jialu Shi; Yang Wang; Tianrenzheng Zhu; Honglei Zhang; Shuofeng Yuan; Jie Zhou; Jasper Fuk-Woo Chan; Kwok-Yung Yuen; Chunfu Xu; Jian Lei; Shengyong Yang; Hin Chu
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Au(I)-based compounds inhibit nsp14/nsp10 and nsp13 (helicase) to exert anti-SARS-CoV-2 properties
errJBIC Journal of Biological Inorganic Chemistry
IF0
err2025-06-18
err0
errOAAI
errJingxin Chen; Xueying Wei; Chun-Lung Chan; Kaiming Tang; Shuofeng Yuan; Hongyan Li; Hongzhe Sun
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errSave
Hepatocyte-expressed HERC2 enhances type I interferon-mediated anti-HBV immune response by promoting K33 ubiquitination of TBK1
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-05-17
err0
PREAI
errZheng, Zhuojun; Cao, Sihang; Liu, Yunzhi; Luo, Jialiang; Wang, Hong; Lu, Xiao; Zhou, Jia; Yuan, Shuofeng; Zuo, Daming; Chen, Qingyun
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errSave
SARS-CoV-2 Membrane Protein Induces MARCHF1/GPX4-Mediated Ferroptosis by Promoting Lipid Accumulation
errJOURNAL OF MEDICAL VIROLOGY
IF4.6
err2025-04-05
err0
PREAI
errSun, Pei; Liu, Qian; Yuan, Shuofeng; Wang, Xin-Tao; Qiu, Ye; Ge, Xing-Yi
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errSave
Reverse genetics-derived cattle H5N1 virus from Clade 2.3.4.4b shows enhanced systemic infectivity and pathogenicity than an older Clade 1 H5N1 virus in BALB/c mice
errEMERGING MICROBES & INFECTIONS
IF7.5
err2025-03-17
err0
errOAAI
errNa Xiao; Xiang Yong Oong; Yanxia Chen; Can Li; Howard Chun-Ho Chung; Pui Wang; Zhanhong Ye; Alvin Hiu-Chung Lam; Jianpiao Cai; Wenchen Song; Andrew Chak-Yiu Lee; Hin Chu; Kin-Hang Kok; Jasper Fuk-Woo Chan; Shuofeng Yuan; Honglin Chen; Kwok-Yung Yuen; Anna Jin-Xia Zhang
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errSave
Lineage-specific pathogenicity, immune evasion, and virological features of SARS-CoV-2 BA.2.86/JN.1 and EG.5.1/HK.3
errNATURE COMMUNICATIONS
IF15.7
err2024-10-09
err1
errOAAI
errLiu, Yuanchen; Zhao, Xiaoyu; Shi, Jialu; Wang, Yajie; Liu, Huan; Hu, Ye-Fan; Hu, Bingjie; Shuai, Huiping; Yuen, Terrence Tsz-Tai; Chai, Yue; Liu, Feifei; Gong, Hua-Rui; Li, Jiayan; Wang, Xun; Jiang, Shujun; Zhang, Xiang; Zhang, Yanliang; Li, Xiangnan; Wang, Lei; Hartnoll, Madeline; Zhu, Tianrenzheng; Hou, Yuxin; Huang, Xiner; Yoon, Chaemin; Wang, Yang; He, Yixin; Zhou, Minmin; Du, Lianzhao; Zhang, Xiaojuan; Chan, Wan-Mui; Chen, Lin-Lei; Cai, Jian-Piao; Yuan, Shuofeng; Zhou, Jie; Huang, Jian-Dong; Yuen, Kwok-Yung; To, Kelvin Kai-Wang; Chan, Jasper Fuk-Woo; Zhang, Bao-Zhong; Sun, Lei; Wang, Pengfei; Chu, Hin
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Co-authors
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William F. DeGrado
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Arieh Warshel
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