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K

Kevin Wiehe

Duke University School of Medicine

44H-index
166Paper Count
9.7KCitation Count
Published Papers 80
Publication Date
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Humans and rhesus macaques share maturation pathways of HIV-1 envelope-reactive V3-glycan bnAb lineages
errScience Translational Medicine
IF14.6
err2026-07-08
err0
PREAI
errMatthew Clark; Hui Li; Mitchell Martin; Tyler D. Evangelous; Sophie M.-C. Gobeil; Madison Berry; Kshitij Wagh; Elena E. Giorgi; Michael P. Hogarty; Chengyan Zhao; Shuyi Wang; Lorie Marchitto; Wenge Ding; Younghoon Park; Juliette Rando; John Carey; Andrew J. Connell; Ashwin N. Skelly; Yue Chen; Seth Rohr; Samantha Balgobin; Chuancang Jiang; Sravani Venkatayogi; Katayoun Mansouri; Robert J. Edwards; Jared Lindenberger; Bhavna Hora; Nicole Doria-Rose; John Mascola; Marit J. van Gils; Rogier W. Sanders; Bette Korber; Beatrice Hahn; Kevin O. Saunders; Priyamvada Acharya; Kevin Wiehe; Barton F. Haynes; George M. Shaw; Wilton B. Williams
errShare
errSave
Induction of broadly neutralizing HIV antibodies by a two-step mechanism informs vaccine design
errScience
IF45.8
err2026-05-07
err0
PREAI
errAshwin N. Skelly; Harry B. Gristick; Hui Li; Edem Gavor; Andrew J. Connell; Edward F. Kreider; Lorie Marchitto; Michael P. Hogarty; Maddy L. Newby; Joel D. Allen; Weimin Liu; Anthony P. West; Kasirajan Ayyanathan; Mary S. Campion; Kaitlyn Winters; Colette G. Gordon; Rebecca A. Osbaldeston; Macy J. Akeley; Emily Lewis; Yingying Li; Ajay Singh; Kendra Cruickshank; Younghoon Park; Chengyan Zhao; Xuduo Li; Khaled Amereh; Elizabeth Van Itallie; John W. Carey; Amie Albertus; Andrew T. DeLaitsch; Jennifer R. Keeffe; Melinda G. Lituchy; Agnes A. Walsh; Daniel J. Morris; Rumi Habib; Frederic Bibollet-Ruche; Nitesh Mishra; Gabriel Avillion; Nicholas S. Koranda; Samantha J. Plante; Christian L. Martella; Jinery Lora; Eric J. D. Wang; Mark G. Lewis; Malcolm A. Martin; Michel C. Nussenzweig; Michael S. Seaman; Darrell J. Irvine; Kevin J. Wiehe; Barton F. Haynes; Kshitij Wagh; Bette Korber; Raiees Andrabi; Max Crispin; Drew Weissman; Pamela J. Bjorkman; Beatrice H. Hahn; George M. Shaw
errShare
errSave
Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV V2 apex broadly neutralizing antibody development
errScience Immunology
IF16.3
err2026-02-13
err0
PREAI
errRumi Habib; Ryan S. Roark; Hui Li; Andrew Jesse Connell; Michael P. Hogarty; Kshitij Wagh; Shuyi Wang; Lorie Marchitto; Ashwin N. Skelly; John W. Carey; Kirsten J. Sowers; Kasirajan Ayyanathan; Samantha J. Plante; Frederic Bibollet-Ruche; Younghoon Park; Colby J. Agostino; Ajay Singh; Christian L. Martella; Emily Lewis; Juliette M. Rando; Neha Chohan; Jinery Lora; Wenge Ding; Mary S. Campion; Chengyan Zhao; Weimin Liu; Yingying Li; Xuduo Li; Bo Liang; Rohan Roy Chowdhury; Khaled Amereh; Elizabeth Van Itallie; Zizhang Sheng; Amrit R. Ghosh; Katharine J. Bar; Wilton B. Williams; Kevin Wiehe; Kevin O. Saunders; Robert J. Edwards; Derek W. Cain; Mark G. Lewis; Facundo D. Batista; Dennis R. Burton; Raiees Andrabi; Daniel W. Kulp; Barton F. Haynes; Bette Korber; Lawrence Shapiro; Peter D. Kwong; Beatrice H. Hahn; George M. Shaw
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errSave
Rapidly acquired HIV-1 neutralization breadth in a rhesus V2 apex knockin mouse model after a single bolus immunization
errScience Immunology
IF16.3
err2026-02-13
err0
PREAI
errAmrit Raj Ghosh; Rumi Habib; Nitesh Mishra; Ryan S. Roark; Madhav Akauliya; Ali A. Albowaidey; Joel D. Allen; Khaled Amereh; Gabriel Avillion; Maria Bottermann; Bo Liang; Namit Chaudhary; Sean Callaghan; Jonathan Dye; Xuduo Li; Jordan R. Ellis-Pugh; Rohan Roy Chowdhury; Nicole E. James; Xiaotie Liu; Laura Maiorino; Paula M. Villavicencio; Rebecca Nedellec; Prabhgun Oberoi; Kirsten J. Sowers; Younghoon Park; Thavaleak Prum; Linette Rodriguez; Maria Ssozi; Jonathan L. Torres; Agnes A. Walsh; John E. Warner; Stephanie R. Weldon; Liling Xu; Kevin Wiehe; Max Crispin; Andrew B. Ward; Usha Nair; Beatrice H. Hahn; Dennis R. Burton; Lawrence Shapiro; Peter D. Kwong; Darrell J. Irvine; Raiees Andrabi; George M. Shaw; Facundo D. Batista
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errSave
On the carrying capacity of the bone marrow survival niche in mice
errFrontiers in Immunology
IF5.9
err2025-11-20
err0
errOAAI
errKeisuke Tonouchi†; Chen-Hao Yeh†; Derek W. Cain; E. Ashley Moseman; Barton F. Haynes; Kshitij Wagh; Kevin Wiehe; Tomohiro Kurosaki; Garnett Kelsoe
errShare
errSave
Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans
errCell
IF42.5
err2025-11-01
err0
errOAAI
errWilton B. Williams; S. Munir Alam; Gilad Ofek; Nathaniel Erdmann; David C. Montefiori; Michael S. Seaman; Kshitij Wagh; Bette Korber; Robert J. Edwards; Katayoun Mansouri; Amanda Eaton; Derek W. Cain; Mitchell Martin; JongIn Hwang; Aria Arus-Altuz; Xiaozhi Lu; Fangping Cai; Nolan Jamieson; Robert Parks; Maggie Barr; Andrew Foulger; Kara Anasti; Parth Patel; Salam Sammour; Ruth J. Parsons; Xiao Huang; Jared Lindenberger; Susan Fetics; Katarzyna Janowska; Aurelie Niyongabo; Benjamin M. Janus; Anagh Astavans; Christopher B. Fox; Ipsita Mohanty; Tyler Evangelous; Yue Chen; Madison Berry; Helene Kirshner; Elizabeth Van Itallie; Kevin O. Saunders; Kevin Wiehe; Kristen W. Cohen; M. Juliana McElrath; Lawrence Corey; Priyamvada Acharya; Stephen R. Walsh; Lindsey R. Baden; Barton F. Haynes
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errSave
Whole-Thorax Irradiation Induces Persistent T Cell Clonal Dysregulation in Pediatric Rhesus Macaques
errRADIATION RESEARCH
IF2.7
err2025-10-01
err0
PREAI
errMacintyre, Andrew N.; Olson, John D.; Balamayooran, Gaya; Dugan, Gregory O.; O'Donnell, Russell P.; Venkatayogi, Sravani; Bourland, J. Daniel; Wiehe, Kevin; Sempowski, Gregory D.; Hale, Laura P.; Cline, J. Mark; Caudell, David L.
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errSave
Computing the inducibility of broadly neutralizing antibodies under a context-dependent model of affinity maturation: applications to sequential vaccine design
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-09-01
err0
errOAAI
errMathews, Joseph; Van Itallie, Elizabeth; Li, Yongkang; Wiehe, Kevin; Schmidler, Scott C.
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errSave
Convergence and divergence of B cell responses in two HIV-1 Env immunizations in Rhesus macaques
errCOMMUNICATIONS MEDICINE
IF6.3
err2025-05-15
err0
errOAAI
errDeLuca, Jenna M.; Blasi, Maria; McGee, Taylor J.; Jha, Shalini; Shen, Xiaoying; Gu, Shuqin; Pollara, Justin; Kerkau, Melissa; Purwar, Mansi; Carnathan, Diane G.; Negri, Donatella; Cara, Andrea; Wollenberg, Kurt; Wiehe, Kevin; Saunders, Kevin O.; Lu, Shan; Silvestri, Guido; Weiner, David B.; Klotman, Mary E.; Ferrari, Guido; Anthony Moody, M.; Bonsignori, Mattia
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errSave
Neonatal immunity associated with heterologous HIV-1 neutralizing antibody induction in SHIV-infected Rhesus Macaques
errNATURE COMMUNICATIONS
IF15.7
err2024-11-27
err0
errOAAI
errHolmes, Sommer; Li, Hui; Shen, Xiaoying; Martin, Mitchell; Tuck, Ryan; Chen, Yue; Giorgi, Elena E.; Kirshner, Helene Fradin; Berry, Madison; Van Italie, Elizabeth; Venkatayogi, Sravani; Beem, Joshua S. Martin; Edwards, Robert J.; Mansouri, Katayoun; Singh, Ajay; Kuykendall, Cindy; Gurley, Thaddeus; Moody, M. Anthony; Denayer, Nicole; Demarco, Todd; Denny, Thomas N.; Wang, Yunfei; Evangelous, Tyler D.; Clinton, John T.; Hora, Bhavna; Wagh, Kshitij; Seaman, Michael S.; Saunders, Kevin O.; Solomotis, Nicholas; Misamore, Johnathan; Lewis, Mark G.; Wiehe, Kevin; Montefiori, David C.; Shaw, George M.; Williams, Wilton B.
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errSave
Engineering immunogens that select for specific mutations in HIV broadly neutralizing antibodies
errNATURE COMMUNICATIONS
IF15.7
err2024-11-03
err0
errOAAI
errHenderson, Rory; Anasti, Kara; Manne, Kartik; Stalls, Victoria; Saunders, Carrie; Bililign, Yishak; Williams, Ashliegh; Bubphamala, Pimthada; Montani, Maya; Kachhap, Sangita; Li, Jingjing; Jaing, Chuancang; Newman, Amanda; Cain, Derek W.; Lu, Xiaozhi; Venkatayogi, Sravani; Berry, Madison; Wagh, Kshitij; Korber, Bette; Saunders, Kevin O.; Tian, Ming; Alt, Fred; Wiehe, Kevin; Acharya, Priyamvada; Alam, S. Munir; Haynes, Barton F.
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errSave
Immunization with germ line-targeting SOSIP trimers elicits broadly neutralizing antibody precursors in infant macaques
errSCIENCE IMMUNOLOGY
IF16.3
err2024-08-30
err1
PREAI
errNelson, Ashley N.; Shen, Xiaoying; Vekatayogi, Sravani; Zhang, Shiyu; Ozorowski, Gabriel; Dennis, Maria; Sewall, Leigh M.; Milligan, Emma; Davis, Dominique; Cross, Kaitlyn A.; Chen, Yue; van Schooten, Jelle; Eudailey, Joshua; Isaac, John; Memon, Saad; Weinbaum, Carolyn; Gao, Hongmei; Stanfield-Oakley, Sherry; Byrd, Alliyah; Chutkan, Suni; Berendam, Stella; Cronin, Kenneth; Yasmeen, Anila; Alam, Munir; Labranche, Celia C.; Rogers, Kenneth; Shirreff, Lisa; Cupo, Albert; Derking, Ronald; Villinger, Francois; Klasse, Per Johan; Ferrari, Guido; Williams, Wilton B.; Hudgens, Michael G.; Ward, Andrew B.; Montefiori, David C.; Van Rompay, Koen K. A.; Wiehe, Kevin; Moore, John P.; Sanders, Rogier W.; De Paris, Kristina; Permar, Sallie R.
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errSave
Vaccination with antigenically complex hemagglutinin mixtures confers broad protection from influenza disease
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2024-05-01
err1
PREAI
errLuo, Zhaochen; Miranda, Hector A.; Burke, Kaitlyn N.; Spurrier, M. Ariel; Berry, Madison; Stover, Erica L.; Spreng, Rachel L.; Waitt, Greg; Soderblom, Erik J.; Macintyre, Andrew N.; Wiehe, Kevin; Heaton, Nicholas S.
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errSave
Prior dengue virus serotype 3 infection modulates subsequent plasmablast responses to Zika virus infection in rhesus macaques
errMBIO
IF4.7
err2024-03-13
err1
errOAAI
errSingh, Tulika; Miller, Itzayana G.; Venkatayogi, Sravani; Webster, Helen; Heimsath, Holly J.; Eudailey, Josh A.; Dudley, Dawn M.; Kumar, Amit; Mangan, Riley J.; Thein, Amelia; Aliota, Matthew T.; Newman, Christina M.; Mohns, Mariel S.; Breitbach, Meghan E.; Berry, Madison; Friedrich, Thomas C.; Wiehe, Kevin; O'Connor, David H.; Permar, Sallie R.
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errSave
Defining genetic diversity of rhesus macaque Fcγ receptors with long-read RNA sequencing
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2024-01-09
err0
errOAAI
errConley, Haleigh E.; He, Max M.; Easterhoff, David; Kirshner, Helene Fradin; Cocklin, Sarah L.; Meyer, Jacob; Hoxie, Taylor; Berry, Madison; Bradley, Todd; Tolbert, William D.; Pazgier, Marzena; Tomaras, Georgia D.; Schmitz, Joern E.; Moody, Michael Anthony; Wiehe, Kevin; Pollara, Justin
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errSave
Multivariate analysis of FcR-mediated NK cell functions identifies unique clustering among humans and rhesus macaques
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2023-12-06
err1
errOAAI
errTuyishime, Marina; Spreng, Rachel L.; Hueber, Brady; Nohara, Junsuke; Goodman, Derrick; Chan, Cliburn; Barfield, Richard; Beck, Whitney E.; Jha, Shalini; Asdell, Stephanie; Wiehe, Kevin; He, Max M.; Easterhoff, David; Conley, Haleigh E.; Hoxie, Taylor; Gurley, Thaddeus; Jones, Caroline; Adhikary, Nihar Deb; Villinger, Francois; Thomas, Rasmi; Denny, Thomas N.; Moody, Michael Anthony; Tomaras, Georgia D.; Pollara, Justin; Reeves, R. Keith; Ferrari, Guido
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errSave
Host immunity associated with spontaneous suppression of viremia in therapy-naIve young rhesus macaques following neonatal SHIV infection
errJOURNAL OF VIROLOGY
IF3.8
err2023-11-30
err2
errOAAI
errEvangelous, Tyler D.; Berry, Madison; Venkatayogi, Sravani; LeMaster, Cas; Geanes, Eric S.; De Naeyer, Nicole; DeMarco, Todd; Shen, Xiaoying; Li, Hui; Hora, Bhavna; Solomonis, Nicholas; Misamore, Johnathan; Lewis, Mark G.; Denny, Thomas N.; Montefiori, David; Shaw, George M.; Wiehe, Kevin; Bradley, Todd; Williams, Wilton B.
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errSave
Conjugation of HIV-1 envelope to hepatitis B surface antigen alters vaccine responses in rhesus macaques
errNPJ VACCINES
IF6.5
err2023-11-24
err0
errOAAI
errNettere, Danielle; Unnithan, Shakthi; Rodgers, Nicole; Nohara, Junsuke; Cray, Paul; Berry, Madison; Jones, Caroline; Armand, Lawrence; Li, Shuk Hang; Berendam, Stella J.; Fouda, Genevieve G.; Cain, Derek W.; Spence, Taylor N.; Granek, Joshua A.; Davenport, Clemontina A.; Edwards, Robert J.; Wiehe, Kevin; Van Rompay, Koen K. A.; Moody, M. Anthony; Permar, Sallie R.; Pollara, Justin
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errSave
ARMADiLLO: a web server for analyzing antibody mutation probabilities
errNUCLEIC ACIDS RESEARCH
IF13.1
err2023-06-01
err4
errOAAI
errBeem, Joshua S. Martin; Venkatayogi, Sravani; Haynes, Barton F.; Wiehe, Kevin
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errSave
Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage
errNATURE COMMUNICATIONS
IF15.7
err2023-05-15
err5
errOAAI
errHenderson, Rory; Zhou, Ye; Stalls, Victoria; Wiehe, Kevin; Saunders, Kevin O.; Wagh, Kshitij; Anasti, Kara; Barr, Maggie; Parks, Robert; Alam, S. Munir; Korber, Bette; Haynes, Barton F.; Bartesaghi, Alberto; Acharya, Priyamvada
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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