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George M. Shaw

University of Pennsylvania

121H-index
398Paper Count
5.5WCitation Count
Published Papers 190
Publication Date
Humans and rhesus macaques share maturation pathways of HIV-1 envelope-reactive V3-glycan bnAb lineages
err2026-07-08
err0
PREAI
errMatthew Clark; Hui Li; Mitchell Martin; Tyler D. Evangelous; Sophie M.-C. Gobeil; Madison Berry; Kshitij Wagh; Elena E. Giorgi; Michael P. Hogarty; Chengyan Zhao; Shuyi Wang; Lorie Marchitto; Wenge Ding; Younghoon Park; Juliette Rando; John Carey; Andrew J. Connell; Ashwin N. Skelly; Yue Chen; Seth Rohr; Samantha Balgobin; Chuancang Jiang; Sravani Venkatayogi; Katayoun Mansouri; Robert J. Edwards; Jared Lindenberger; Bhavna Hora; Nicole Doria-Rose; John Mascola; Marit J. van Gils; Rogier W. Sanders; Bette Korber; Beatrice Hahn; Kevin O. Saunders; Priyamvada Acharya; Kevin Wiehe; Barton F. Haynes; George M. Shaw; Wilton B. Williams
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Enhanced B cell priming induces broadly neutralizing HIV-1 apex antibodies
errNature
IF48.5
err2026-06-30
err0
PREAI
errLorie Marchitto; Kshitij Wagh; Ryan S. Roark; Severin Coleon; Hui Li; Ashwin N. Skelly; Michael P. Hogarty; Rumi Habib; Wenge Ding; Kasirajan Ayyanathan; Weimin Liu; Zizhang Sheng; Yicheng Guo; Joena Bal; Lena M. Smith; Laura L. Sutherland; Younghoon Park; Andrew J. Connell; Frederic Bibollet-Ruche; Emily Lewis; Samantha J. Plante; Macy J. Akeley; Jinery Lora; Chengyan Zhao; John W. Carey; Christian L. Martella; Yingying Li; Mary S. Campion; Melinda G. Lituchy; Rebecca A. Osbaldeston; Colette G. Gordon; Amie Albertus; Justin Su; Chiaki Noguchi; Ying K. Tam; Christopher Barbosa; Bo Liang; Khaled Amereh; Xuduo Li; Agnes A. Walsh; Darrell J. Irvine; Raiees Andrabi; Robert J. Edwards; Edward F. Kreider; Drew Weissman; Lawrence Shapiro; Peter D. Kwong; Bette T. Korber; Barton F. Haynes; Kevin O. Saunders; Beatrice H. Hahn; George M. Shaw
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Induction of broadly neutralizing HIV antibodies by a two-step mechanism informs vaccine design
errScience
IF45.8
err2026-05-07
err0
PREAI
errAshwin N. Skelly; Harry B. Gristick; Hui Li; Edem Gavor; Andrew J. Connell; Edward F. Kreider; Lorie Marchitto; Michael P. Hogarty; Maddy L. Newby; Joel D. Allen; Weimin Liu; Anthony P. West; Kasirajan Ayyanathan; Mary S. Campion; Kaitlyn Winters; Colette G. Gordon; Rebecca A. Osbaldeston; Macy J. Akeley; Emily Lewis; Yingying Li; Ajay Singh; Kendra Cruickshank; Younghoon Park; Chengyan Zhao; Xuduo Li; Khaled Amereh; Elizabeth Van Itallie; John W. Carey; Amie Albertus; Andrew T. DeLaitsch; Jennifer R. Keeffe; Melinda G. Lituchy; Agnes A. Walsh; Daniel J. Morris; Rumi Habib; Frederic Bibollet-Ruche; Nitesh Mishra; Gabriel Avillion; Nicholas S. Koranda; Samantha J. Plante; Christian L. Martella; Jinery Lora; Eric J. D. Wang; Mark G. Lewis; Malcolm A. Martin; Michel C. Nussenzweig; Michael S. Seaman; Darrell J. Irvine; Kevin J. Wiehe; Barton F. Haynes; Kshitij Wagh; Bette Korber; Raiees Andrabi; Max Crispin; Drew Weissman; Pamela J. Bjorkman; Beatrice H. Hahn; George M. Shaw
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Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV V2 apex broadly neutralizing antibody development
err2026-02-13
err0
PREAI
errRumi Habib; Ryan S. Roark; Hui Li; Andrew Jesse Connell; Michael P. Hogarty; Kshitij Wagh; Shuyi Wang; Lorie Marchitto; Ashwin N. Skelly; John W. Carey; Kirsten J. Sowers; Kasirajan Ayyanathan; Samantha J. Plante; Frederic Bibollet-Ruche; Younghoon Park; Colby J. Agostino; Ajay Singh; Christian L. Martella; Emily Lewis; Juliette M. Rando; Neha Chohan; Jinery Lora; Wenge Ding; Mary S. Campion; Chengyan Zhao; Weimin Liu; Yingying Li; Xuduo Li; Bo Liang; Rohan Roy Chowdhury; Khaled Amereh; Elizabeth Van Itallie; Zizhang Sheng; Amrit R. Ghosh; Katharine J. Bar; Wilton B. Williams; Kevin Wiehe; Kevin O. Saunders; Robert J. Edwards; Derek W. Cain; Mark G. Lewis; Facundo D. Batista; Dennis R. Burton; Raiees Andrabi; Daniel W. Kulp; Barton F. Haynes; Bette Korber; Lawrence Shapiro; Peter D. Kwong; Beatrice H. Hahn; George M. Shaw
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Rapidly acquired HIV-1 neutralization breadth in a rhesus V2 apex knockin mouse model after a single bolus immunization
err2026-02-13
err0
PREAI
errAmrit Raj Ghosh; Rumi Habib; Nitesh Mishra; Ryan S. Roark; Madhav Akauliya; Ali A. Albowaidey; Joel D. Allen; Khaled Amereh; Gabriel Avillion; Maria Bottermann; Bo Liang; Namit Chaudhary; Sean Callaghan; Jonathan Dye; Xuduo Li; Jordan R. Ellis-Pugh; Rohan Roy Chowdhury; Nicole E. James; Xiaotie Liu; Laura Maiorino; Paula M. Villavicencio; Rebecca Nedellec; Prabhgun Oberoi; Kirsten J. Sowers; Younghoon Park; Thavaleak Prum; Linette Rodriguez; Maria Ssozi; Jonathan L. Torres; Agnes A. Walsh; John E. Warner; Stephanie R. Weldon; Liling Xu; Kevin Wiehe; Max Crispin; Andrew B. Ward; Usha Nair; Beatrice H. Hahn; Dennis R. Burton; Lawrence Shapiro; Peter D. Kwong; Darrell J. Irvine; Raiees Andrabi; George M. Shaw; Facundo D. Batista
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Mechanisms of early-life immunity associated with induction of heterologous HIV-1 neutralizing antibodies
err2025-11-01
err0
PREAI
errHolmes, Sommer; Li, Hui; Shen, Shaunna; Martin, Mitchell; Tuck, Ryan; Chen, Yue; Giorgi, Elena; Kirshner, Helene; Berry, Madison; Van Italie, Elizabeth; Venkatayogi, Sravani; Beem, Josh; Edwards, Robert; Mansouri, Katayoun; Denayer, Nicole; Demarco, Todd; Denny, Thomas; Kuykendall, Cindy; Gurley, Thaddeus; Moody, Anthony; Wang, Yunfei; Evangelous, Tyler; Clinton, John; Hora, Bhavna; Wagh, Kshitij; Seaman, Michael; Saunders, Kevin; Solomotis, Nicholas; Misamore, Johnathan; Lewis, Mark; Wiehe, Kevin; Montefiori, David; Shaw, George; Williams, Wilton
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Status of HIV vaccine development: progress and promise
err2025-05-15
err0
errOAAI
errHaynes, Barton F.; Saunders, Kevin O.; Hahn, Beatrice H.; Wiehe, Kevin; Baden, Lindsey R.; Shaw, George M.
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Persistence of CMV-specific anti-HIV CAR T cells after adoptive immunotherapy
err2025-04-01
err0
errOAAI
errWu, Chengxiang; Johnson, Nathan M.; Yu, Shan; Lo, Agnes S.; Sahu, Gautam K.; Marx, Preston A.; von Laer, Dorothee; Skowron, Gail; Geleziunas, Romas; Shaw, George M.; Kaur, Amitinder; Junghans, Richard P.; Braun, Stephen E.
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Assessing the impact of autologous virus neutralizing antibodies on viral rebound time in postnatally SHIV-infected ART-treated infant rhesus macaques
err2024-09-01
err0
errOAAI
errMainou, Ellie; Berendam, Stella J.; Obregon-Perko, Veronica; Uffman, Emilie A.; Phan, Caroline T.; Shaw, George M.; Bar, Katharine J.; Kumar, Mithra R.; Fray, Emily J.; Siliciano, Janet M.; Siliciano, Robert F.; Silvestri, Guido; Permar, Sallie R.; Fouda, Genevieve G.; McCarthy, Janice; Chahroudi, Ann; Conway, Jessica M.; Chan, Cliburn
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Viral Envelope Evolution in Simian-HIV-Infected Neonate and Adult-Dam Pairs of Rhesus Macaques
err2024-06-25
err0
errOAAI
errGiorgi, Elena E.; Li, Hui; Hora, Bhavna; Shaw, George M.; Wagh, Kshitij; Williams, Wilton B.
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Longitudinal Analysis of HIV-1 Fusion Peptide-Directed Neutralizing Response in a Vaccinated Macaque Following SHIV Infection
err2024-05-01
err0
PREAI
errHwang, Juyun; Wang, Hua; Dal Santo, James; Howe, Colin; Cheng, Cheng; Doria-Rose, Nicole; Shaw, George; Koup, Richard; Mascola, John; Kwong, Peter; Pierson, Theodore
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Antibodies targeting the fusion peptide on the HIV envelope provide protection to rhesus macaques against mucosal SHIV challenge
err2024-01-17
err3
PREAI
errPegu, Amarendra; Lovelace, Sarah E.; Demouth, Megan E.; Cully, Michelle D.; Morris, Daniel J.; Li, Yingying; Wang, Keyun; Schmidt, Stephen D.; Choe, Misook; Liu, Cuiping; Chen, Xuejun; Viox, Elise; Rowshan, Ariana; Taft, Justin D.; Zhang, Baoshan; Xu, Kai; Duan, Hongying; Ou, Li; Todd, John-Paul; Kong, Rui; Li, Hui; Shaw, George M.; Doria-Rose, Nicole A.; Kwong, Peter D.; Koup, Richard A.; Mascola, John R.
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Neutralizing antibodies evolve to exploit vulnerable sites in the HCV envelope glycoprotein E2 and mediate spontaneous clearance of infection
errIMMUNITY
IF26.3
err2024-01-01
err5
errOAAI
errFrumento, Nicole; Sinnis-Bourozikas, Ariadne; Paul, Harry T.; Stavrakis, Georgia; Zahid, Muhammad N.; Wang, Shuyi; Ray, Stuart C.; Flyak, Andrew I.; Shaw, George M.; Cox, Andrea L.; Bailey, Justin R.
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Host immunity associated with spontaneous suppression of viremia in therapy-naIve young rhesus macaques following neonatal SHIV infection
err2023-11-30
err2
errOAAI
errEvangelous, Tyler D.; Berry, Madison; Venkatayogi, Sravani; LeMaster, Cas; Geanes, Eric S.; De Naeyer, Nicole; DeMarco, Todd; Shen, Xiaoying; Li, Hui; Hora, Bhavna; Solomonis, Nicholas; Misamore, Johnathan; Lewis, Mark G.; Denny, Thomas N.; Montefiori, David; Shaw, George M.; Wiehe, Kevin; Bradley, Todd; Williams, Wilton B.
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Intradermal but not intramuscular modified vaccinia Ankara immunizations protect against intravaginal tier2 simian-human immunodeficiency virus challenges in female macaques
err2023-08-08
err4
errOAAI
errBollimpelli, Venkata S. S.; Reddy, Pradeep B. J.; Gangadhara, Sailaja; Charles, Tysheena P. P.; Burton, Samantha L. L.; Tharp, Gregory K. K.; Styles, Tiffany M. M.; Labranche, Celia C. C.; Smith, Justin C. C.; Upadhyay, Amit A. A.; Sahoo, Anusmita; Legere, Traci; Shiferaw, Ayalnesh; Velu, Vijayakumar; Yu, Tianwei; Tomai, Mark; Vasilakos, John; Kasturi, Sudhir P. P.; Shaw, George M. M.; Montefiori, David; Bosinger, Steven E. E.; Kozlowski, Pamela A. A.; Pulendran, Bali; Derdeyn, Cynthia A. A.; Hunter, Eric; Amara, Rama R. R.
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Efficient ex vivo expansion of conserved element vaccine-specific CD8+T-cells from SHIV-infected, ART-suppressed nonhuman primates
err2023-05-03
err3
errOAAI
errDross, Sandra; Venkataraman, Rasika; Patel, Shabnum; Huang, Meei-Li; Bollard, Catherine M.; Rosati, Margherita; Pavlakis, George N.; Felber, Barbara K.; Bar, Katharine J.; Shaw, George M.; Jerome, Keith R.; Mullins, James I.; Kiem, Hans-Peter; Fuller, Deborah Heydenburg; Peterson, Christopher W.
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Neonatal SHIV infection in rhesus macaques elicited heterologous HIV-1-neutralizing antibodies
err2023-03-01
err4
errOAAI
errHora, Bhavna; Li, Hui; Shen, Xiaoying; Martin, Mitchell; Chen, Yue; Berry, Madison; Evangelous, Tyler; Macintyre, Andrew N.; Arus-Altuz, Aria; Wang, Shuyi; Singh, Ajay; Zhao, Chengyan; De Naeyer, Nicole; DeMarco, Todd; Kuykendall, Cindy; Gurley, Thaddeus; Saunders, Kevin O.; Denny, Thomas; Moody, M. Anthony; Misamore, John; Lewis, Mark G.; Wiehe, Kevin; Cain, Derek W.; Montefiori, David C.; Shaw, George M.; Williams, Wilton B.
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Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies(vol 23, pg 142, 2023)
err2023-03-01
err3
errOAAI
errHaynes, Barton F.; Wiehe, Kevin; Borrow, Persephone; Saunders, Kevin O.; Korber, Bette; Wagh, Kshitij; McMichael, Andrew J.; Kelsoe, Garnett; Hahn, Beatrice H.; Alt, Frederick; Shaw, George M.
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A Germline-Targeting Chimpanzee SIV Envelope Glycoprotein Elicits a New Class of V2-Apex Directed Cross-Neutralizing Antibodies
errMBIO
IF4.7
err2023-02-28
err4
errOAAI
errBibollet-Ruche, Frederic; Russell, Ronnie M. M.; Ding, Wenge; Liu, Weimin; Li, Yingying; Wagh, Kshitij; Wrapp, Daniel; Habib, Rumi; Skelly, Ashwin N. N.; Roark, Ryan S. S.; Sherrill-Mix, Scott; Wang, Shuyi; Rando, Juliette; Lindemuth, Emily; Cruickshank, Kendra; Park, Younghoon; Baum, Rachel; Carey, John W. W.; Connell, Andrew Jesse; Li, Hui; Giorgi, Elena E. E.; Song, Ge S. S.; Ding, Shilei; Finzi, Andres; Newman, Amanda; Hernandez, Giovanna E. E.; Machiele, Emily; Cain, Derek W. W.; Mansouri, Katayoun; Lewis, Mark G. G.; Montefiori, David C. C.; Wiehe, Kevin J. J.; Alam, S. Munir; Teng, I-Ting; Kwong, Peter D. D.; Andrabi, Raiees; Verkoczy, Laurent; Burton, Dennis R. R.; Korber, Bette T. T.; Saunders, Kevin O. O.; Haynes, Barton F. F.; Edwards, Robert J. J.; Shaw, George M. M.; Hahn, Beatrice H. H.
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Stabilized HIV-1 envelope immunization induces neutralizing antibodies to the CD4bs and protects macaques against mucosal infection
err2022-09-07
err18
errOAAI
errSaunders, Kevin O.; Edwards, Robert J.; Tilahun, Kedamawit; Manne, Kartik; Lu, Xiaozhi; Cain, Derek W.; Wiehe, Kevin; Williams, Wilton B.; Mansouri, Katayoun; Hernandez, Giovanna E.; Sutherland, Laura; Scearce, Richard; Parks, Robert; Barr, Maggie; DeMarco, Todd; Eater, Chloe M.; Eaton, Amanda; Morton, Georgeanna; Mildenberg, Benjamin; Wang, Yunfei; Rountree, R. Wes; Tomai, Mark A.; Fox, Christopher B.; Moody, M. Anthony; Alam, S. Munir; Santra, Sampa; Lewis, Mark G.; Denny, Thomas N.; Shaw, George M.; Montefiori, David C.; Acharya, Priyamvada; Haynes, Barton F.
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