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K

Kevin O. Saunders

Duke University School of Medicine

50H-index
210Paper Count
9.7KCitation Count
Published Papers 98
Publication Date
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Humans and rhesus macaques share maturation pathways of HIV-1 envelope-reactive V3-glycan bnAb lineages
errScience Translational Medicine
IF14.6
err2026-07-08
err0
PREAI
errMatthew Clark; Hui Li; Mitchell Martin; Tyler D. Evangelous; Sophie M.-C. Gobeil; Madison Berry; Kshitij Wagh; Elena E. Giorgi; Michael P. Hogarty; Chengyan Zhao; Shuyi Wang; Lorie Marchitto; Wenge Ding; Younghoon Park; Juliette Rando; John Carey; Andrew J. Connell; Ashwin N. Skelly; Yue Chen; Seth Rohr; Samantha Balgobin; Chuancang Jiang; Sravani Venkatayogi; Katayoun Mansouri; Robert J. Edwards; Jared Lindenberger; Bhavna Hora; Nicole Doria-Rose; John Mascola; Marit J. van Gils; Rogier W. Sanders; Bette Korber; Beatrice Hahn; Kevin O. Saunders; Priyamvada Acharya; Kevin Wiehe; Barton F. Haynes; George M. Shaw; Wilton B. Williams
errShare
errSave
Enhanced B cell priming induces broadly neutralizing HIV-1 apex antibodies
errNature
IF48.5
err2026-06-30
err0
PREAI
errLorie Marchitto; Kshitij Wagh; Ryan S. Roark; Severin Coleon; Hui Li; Ashwin N. Skelly; Michael P. Hogarty; Rumi Habib; Wenge Ding; Kasirajan Ayyanathan; Weimin Liu; Zizhang Sheng; Yicheng Guo; Joena Bal; Lena M. Smith; Laura L. Sutherland; Younghoon Park; Andrew J. Connell; Frederic Bibollet-Ruche; Emily Lewis; Samantha J. Plante; Macy J. Akeley; Jinery Lora; Chengyan Zhao; John W. Carey; Christian L. Martella; Yingying Li; Mary S. Campion; Melinda G. Lituchy; Rebecca A. Osbaldeston; Colette G. Gordon; Amie Albertus; Justin Su; Chiaki Noguchi; Ying K. Tam; Christopher Barbosa; Bo Liang; Khaled Amereh; Xuduo Li; Agnes A. Walsh; Darrell J. Irvine; Raiees Andrabi; Robert J. Edwards; Edward F. Kreider; Drew Weissman; Lawrence Shapiro; Peter D. Kwong; Bette T. Korber; Barton F. Haynes; Kevin O. Saunders; Beatrice H. Hahn; George M. Shaw
errShare
errSave
Mechanistic and antigenic boundaries of Henipavirus and Parahenipavirus glycoproteins
errNature Communications
IF15.7
err2026-06-19
err0
errOAAI
errAaron J. May; Muralikrishna Lella; Jared Lindenberger; Alex Berkman; Ujjwal Kumar; Kejun Liu; Moumita Dutta; Maggie Barr; Rob Parks; Xiaozhi Lu; Madison Berry; Amanda Powell; Amelia G. Thompson; Sravya Sowdamini Nakka; Camila T. França; Xiao Huang; Arpita Mrigwani; Kijun Song; Victor Ilevbare; Salam Sammour; Chan Soo Park; Radha Devkota Adhikari; Priyanka Devkota; Katarzyna Janowska; Yanshun Liu; Garrett Scapellato; Taylor N. Spence; Katayoun Mansouri; Kevin Wiehe; Nancy J. Sullivan; Rosemarie Mason; Robert J. Edwards; Kevin O. Saunders; Barton F. Haynes; Priyamvada Acharya
errShare
errSave
Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV V2 apex broadly neutralizing antibody development
errScience Immunology
IF16.3
err2026-02-13
err0
PREAI
errRumi Habib; Ryan S. Roark; Hui Li; Andrew Jesse Connell; Michael P. Hogarty; Kshitij Wagh; Shuyi Wang; Lorie Marchitto; Ashwin N. Skelly; John W. Carey; Kirsten J. Sowers; Kasirajan Ayyanathan; Samantha J. Plante; Frederic Bibollet-Ruche; Younghoon Park; Colby J. Agostino; Ajay Singh; Christian L. Martella; Emily Lewis; Juliette M. Rando; Neha Chohan; Jinery Lora; Wenge Ding; Mary S. Campion; Chengyan Zhao; Weimin Liu; Yingying Li; Xuduo Li; Bo Liang; Rohan Roy Chowdhury; Khaled Amereh; Elizabeth Van Itallie; Zizhang Sheng; Amrit R. Ghosh; Katharine J. Bar; Wilton B. Williams; Kevin Wiehe; Kevin O. Saunders; Robert J. Edwards; Derek W. Cain; Mark G. Lewis; Facundo D. Batista; Dennis R. Burton; Raiees Andrabi; Daniel W. Kulp; Barton F. Haynes; Bette Korber; Lawrence Shapiro; Peter D. Kwong; Beatrice H. Hahn; George M. Shaw
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errSave
A neutralizing human antibody induces movement of the HCoV-229E receptor binding domain
errCommunications Biology
IF5.1
err2025-12-31
err0
errOAAI
errMera F. Liccione; Trevor Scobey; Heather M. Froggatt; Camryn Pajon; Boyd L. Yount; Qi Yin; Taylor N. Spence; Emmanuel B. Walter; Kevin O. Saunders; Robert J. Edwards; Ralph S. Baric; Barton F. Haynes; Derek W. Cain; Timothy P. Sheahan; Daniel Wrapp
errShare
errSave
Mechanisms of early-life immunity associated with induction of heterologous HIV-1 neutralizing antibodies
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errHolmes, Sommer; Li, Hui; Shen, Shaunna; Martin, Mitchell; Tuck, Ryan; Chen, Yue; Giorgi, Elena; Kirshner, Helene; Berry, Madison; Van Italie, Elizabeth; Venkatayogi, Sravani; Beem, Josh; Edwards, Robert; Mansouri, Katayoun; Denayer, Nicole; Demarco, Todd; Denny, Thomas; Kuykendall, Cindy; Gurley, Thaddeus; Moody, Anthony; Wang, Yunfei; Evangelous, Tyler; Clinton, John; Hora, Bhavna; Wagh, Kshitij; Seaman, Michael; Saunders, Kevin; Solomotis, Nicholas; Misamore, Johnathan; Lewis, Mark; Wiehe, Kevin; Montefiori, David; Shaw, George; Williams, Wilton
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errSave
Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans
errCell
IF42.5
err2025-11-01
err0
errOAAI
errWilton B. Williams; S. Munir Alam; Gilad Ofek; Nathaniel Erdmann; David C. Montefiori; Michael S. Seaman; Kshitij Wagh; Bette Korber; Robert J. Edwards; Katayoun Mansouri; Amanda Eaton; Derek W. Cain; Mitchell Martin; JongIn Hwang; Aria Arus-Altuz; Xiaozhi Lu; Fangping Cai; Nolan Jamieson; Robert Parks; Maggie Barr; Andrew Foulger; Kara Anasti; Parth Patel; Salam Sammour; Ruth J. Parsons; Xiao Huang; Jared Lindenberger; Susan Fetics; Katarzyna Janowska; Aurelie Niyongabo; Benjamin M. Janus; Anagh Astavans; Christopher B. Fox; Ipsita Mohanty; Tyler Evangelous; Yue Chen; Madison Berry; Helene Kirshner; Elizabeth Van Itallie; Kevin O. Saunders; Kevin Wiehe; Kristen W. Cohen; M. Juliana McElrath; Lawrence Corey; Priyamvada Acharya; Stephen R. Walsh; Lindsey R. Baden; Barton F. Haynes
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errSave
Acquisition of quaternary trimer interaction as a key step in the lineage maturation of a broad and potent HIV-1 neutralizing antibody
errStructure
IF4.3
err2025-05-23
err0
PREAI
errQingbo Liu; Ruth J. Parsons; Kevin Wiehe; Robert J. Edwards; Kevin O. Saunders; Peng Zhang; Huiyi Miao; Kedamawit Tilahun; Julia Jones; Yue Chen; Bhavna Hora; Wilton B. Williams; David Easterhoff; Xiao Huang; Katarzyna Janowska; Katayoun Mansouri; Barton F. Haynes; Priyamvada Acharya; Paolo Lusso
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errSave
Convergence and divergence of B cell responses in two HIV-1 Env immunizations in Rhesus macaques
errCOMMUNICATIONS MEDICINE
IF6.3
err2025-05-15
err0
errOAAI
errDeLuca, Jenna M.; Blasi, Maria; McGee, Taylor J.; Jha, Shalini; Shen, Xiaoying; Gu, Shuqin; Pollara, Justin; Kerkau, Melissa; Purwar, Mansi; Carnathan, Diane G.; Negri, Donatella; Cara, Andrea; Wollenberg, Kurt; Wiehe, Kevin; Saunders, Kevin O.; Lu, Shan; Silvestri, Guido; Weiner, David B.; Klotman, Mary E.; Ferrari, Guido; Anthony Moody, M.; Bonsignori, Mattia
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errSave
Status of HIV vaccine development: progress and promise
errJOURNAL OF THE INTERNATIONAL AIDS SOCIETY
IF4.9
err2025-05-15
err0
errOAAI
errHaynes, Barton F.; Saunders, Kevin O.; Hahn, Beatrice H.; Wiehe, Kevin; Baden, Lindsey R.; Shaw, George M.
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errSave
Neonatal immunity associated with heterologous HIV-1 neutralizing antibody induction in SHIV-infected Rhesus Macaques
errNATURE COMMUNICATIONS
IF15.7
err2024-11-27
err0
errOAAI
errHolmes, Sommer; Li, Hui; Shen, Xiaoying; Martin, Mitchell; Tuck, Ryan; Chen, Yue; Giorgi, Elena E.; Kirshner, Helene Fradin; Berry, Madison; Van Italie, Elizabeth; Venkatayogi, Sravani; Beem, Joshua S. Martin; Edwards, Robert J.; Mansouri, Katayoun; Singh, Ajay; Kuykendall, Cindy; Gurley, Thaddeus; Moody, M. Anthony; Denayer, Nicole; Demarco, Todd; Denny, Thomas N.; Wang, Yunfei; Evangelous, Tyler D.; Clinton, John T.; Hora, Bhavna; Wagh, Kshitij; Seaman, Michael S.; Saunders, Kevin O.; Solomotis, Nicholas; Misamore, Johnathan; Lewis, Mark G.; Wiehe, Kevin; Montefiori, David C.; Shaw, George M.; Williams, Wilton B.
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errSave
Engineering immunogens that select for specific mutations in HIV broadly neutralizing antibodies
errNATURE COMMUNICATIONS
IF15.7
err2024-11-03
err0
errOAAI
errHenderson, Rory; Anasti, Kara; Manne, Kartik; Stalls, Victoria; Saunders, Carrie; Bililign, Yishak; Williams, Ashliegh; Bubphamala, Pimthada; Montani, Maya; Kachhap, Sangita; Li, Jingjing; Jaing, Chuancang; Newman, Amanda; Cain, Derek W.; Lu, Xiaozhi; Venkatayogi, Sravani; Berry, Madison; Wagh, Kshitij; Korber, Bette; Saunders, Kevin O.; Tian, Ming; Alt, Fred; Wiehe, Kevin; Acharya, Priyamvada; Alam, S. Munir; Haynes, Barton F.
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errSave
Isolation and characterization of IgG3 glycan-targeting antibodies with exceptional cross-reactivity for diverse viral families
errPLOS PATHOGENS
IF4.9
err2024-09-18
err1
errOAAI
errVukovich, Matthew J.; Shiakolas, Andrea R.; Lindenberger, Jared; Richardson, Robert A.; Bass, Lindsay E.; Barr, Maggie; Liu, Yanshun; Go, Eden P.; Park, Chan Soo; May, Aaron J.; Sammour, Salam; Kambarami, Chipo; Huang, Xiao; Janowska, Katarzyna; Edwards, Robert J.; Mansouri, Katayoun; Spence, Taylor N.; Abu-Shmais, Alexandra A.; Manamela, Nelia P.; Richardson, Simone I.; Leonard, Sabina E. W.; Gripenstraw, Kathryn R.; Setliff, Ian; Saunders, Kevin O.; Bonami, Rachel H.; Ross, Ted M.; Desaire, Heather; Moore, Penny L.; Parks, Robert; Haynes, Barton F.; Sheward, Daniel J.; Acharya, Priyamvada; Sautto, Giuseppe A.; Georgiev, Ivelin S.
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Comparison of the immunogenicity of mRNA-encoded and protein HIV-1 Env-ferritin nanoparticle designs
errJOURNAL OF VIROLOGY
IF3.8
err2024-09-17
err1
PREAI
errMu, Zekun; Whitley, Jill; Martik, Diana; Sutherland, Laura; Newman, Amanda; Barr, Maggie; Parks, Robert; Wiehe, Kevin; Cain, Derek W.; Hodges, Katrina Z.; Venkatayogi, Sravani; Lee, Esther M.; Smith, Lena; Mansouri, Katayoun; Edwards, Robert J.; Wang, Yunfei; Rountree, Wes; Alameh, Mohamad-Gabriel; Tam, Ying; Barbosa, Christopher; Tomai, Mark; Lewis, Mark G.; Santrai, Sampa; Maughan, Maureen; Tian, Ming; Alt, Frederick W.; Weissman, Drew; Saunders, Kevin O.; Haynes, Barton F.
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errSave
SARS-CoV-2 Omicron XBB lineage spike structures, conformations, antigenicity, and receptor recognition
errMOLECULAR CELL
IF16.6
err2024-07-01
err0
errOAAI
errZhang, Qianyi E.; Lindenberger, Jared; Parsons, Ruth J.; Thakur, Bhishem; Parks, Rob; Park, Chan Soo; Huang, Xiao; Sammour, Salam; Janowska, Katarzyna; Spence, Taylor N.; Edwards, Robert J.; Martin, Mitchell; Williams, Wilton B.; Gobeil, Sophie; Montefiori, David C.; Korber, Bette; Saunders, Kevin O.; Haynes, Barton F.; Henderson, Rory; Acharya, Priyamvada
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errSave
Non-neutralizing SARS-CoV-2 N-terminal domain antibodies protect mice against severe disease using Fc-mediated effector functions
errPLOS PATHOGENS
IF4.9
err2024-06-20
err6
errOAAI
errPierre, Camille N.; Adams, Lily E.; Higgins, Jaclyn S.; Anasti, Kara; Goodman, Derrick; Mielke, Dieter; Stanfield-Oakley, Sherry; Powers, John M.; Li, Dapeng; Rountree, Wes; Wang, Yunfei; Edwards, Robert J.; Alam, S. Munir; Ferrari, Guido; Tomaras, Georgia D.; Haynes, Barton F.; Baric, Ralph S.; Saunders, Kevin O.
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Microsecond dynamics control the HIV-1 Envelope conformation
errSCIENCE ADVANCES
IF12.5
err2024-02-02
err3
errOAAI
errBennett, Ashley L.; Edwards, Robert; Kosheleva, Irina; Saunders, Carrie; Bililign, Yishak; Williams, Ashliegh; Bubphamala, Pimthada; Manosouri, Katayoun; Anasti, Kara; Saunders, Kevin O.; Alam, S. Munir; Haynes, Barton F.; Acharya, Priyamvada; Henderson, Rory
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errSave
Vaccine-mediated protection against Merbecovirus and Sarbecovirus challenge in mice
errCELL REPORTS
IF6.9
err2023-10-01
err6
errOAAI
errMartinez, David R.; Schafer, Alexandra; Gavitt, Tyler D.; Mallory, Michael L.; Lee, Esther; Catanzaro, Nicholas J.; Chen, Haiyan; Gully, Kendra; Scobey, Trevor; Korategere, Pooja; Brown, Alecia; Smith, Lena; Parks, Robert; Barr, Maggie; Newman, Amanda; Bowman, Cindy; Powers, John M.; Soderblom, Erik J.; Mansouri, Katayoun; Edwards, Robert J.; Baric, Ralph S.; Haynes, Barton F.; Saunders, Kevin O.
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errSave
Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage
errNATURE COMMUNICATIONS
IF15.7
err2023-05-15
err5
errOAAI
errHenderson, Rory; Zhou, Ye; Stalls, Victoria; Wiehe, Kevin; Saunders, Kevin O.; Wagh, Kshitij; Anasti, Kara; Barr, Maggie; Parks, Robert; Alam, S. Munir; Korber, Bette; Haynes, Barton F.; Bartesaghi, Alberto; Acharya, Priyamvada
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errSave
Progress in vaccine development for infectious diseases-a Keystone Symposia report
errANNALS OF THE NEW YORK ACADEMY OF SCIENCES
IF4.8
err2023-04-05
err4
PREAI
errCable, Jennifer; Graham, Barney S.; Koup, Richard A.; Seder, Robert A.; Kariko, Katalin; Pardi, Norbert; Barouch, Dan H.; Sharma, Bhawna; Rauch, Susanne; Nachbagauer, Raffael; Forsell, Mattias N. E.; Schotsaert, Michael; Ellebedy, Ali H.; Lore, Karin; Irvine, Darrell J.; Pilkington, Emily; Tahtinen, Siri; Thompson, Elizabeth A.; Feraoun, Yanis; King, Neil P.; Saunders, Kevin; Alter, Galit; Moin, Syed M.; Sliepen, Kwinten; Karlsson Hedestam, Gunilla B.; Wardemann, Hedda; Pulendran, Bali; Doria-Rose, Nicole A.; He, Wan-Ting; Juno, Jennifer A.; Ataca, Sila; Wheatley, Adam K.; McLellan, Jason S.; Walker, Laura M.; Lederhofer, Julia; Lindesmith, Lisa C.; Wille, Holger; Hotez, Peter J.; Bekker, Linda-Gail
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Research Directions

No research directions
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