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Michaela U. Gack

cleveland clinic

50H-index
134Paper Count
1.6WCitation Count
Published Papers 79
Publication Date
Virus-induced deconjugation of ISG15 dysregulates innate immunity and cellular metabolism
errImmunity
IF26.3
err2026-08-06
err0
PREAI
errJunji Zhu; GuanQun Liu; Jielin Xu; Zuberwasim Sayyad; Kun Li; Surajit Chakraborty; Christopher M. Goins; Huaxu Yu; Yadi Zhou; Shanti Ross; Evangeline White; Jun Zhao; Oliver Fiehn; Shaun R. Stauffer; Feixiong Cheng; Michaela U. Gack
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Cryo-EM structures of UBA6 reveal mechanisms of E1–E2 specificity and dual FAT10/ubiquitin thioester transfer
err2026-02-28
err0
errOAAI
errDigant Nayak; Lijia Jia; Priscila dos Santos Bury; Eliza A. Ruben; Ankita Shukla; Anindita Nayak; Caleb M. Stratton; Pirouz Ebadi; Hee Cho; Anna A. Tumanova; Joyce T. Varughese; Lingmin Yuan; Fei Gao; Kristin E. Cano; Christopher Davies; Patrick Sung; Michaela U. Gack; Elizabeth V. Wasmuth; Shaun K. Olsen
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Nef stabilizes actin to prevent HIV-1 sensing by RIG-I-like receptors
err2025-12-07
err0
errOAAI
errAlexandre Laliberté; Caterina Prelli Bozzo; Dhiraj Acharya; Aurora De Luna; Maximilian Hirschenberger; Junji Zhu; Meta Volcic; Bettina Stolp; Cristina M. Rodriguez-Quinteros; Oliver T. Fackler; Michaela U. Gack; Konstantin M. J. Sparrer; Frank Kirchhoff
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Viral deISGylase activity antagonizes the host innate immune response and enhances coronavirus pathogenesis in a murine model of coronavirus infection
err2025-11-01
err0
PREAI
errAli, Mudassir; O'brien, Amornrat; Moreira, Fernando; Sarkar, Lucky; Gack, Michaela; Baker, Susan
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The RIG-I-like receptor family of immune proteins
err2025-10-16
err0
errOAAI
errMariska van Huizen; Michaela U. Gack
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TRIM Proteins: Key Regulators of Immunity to Herpesvirus Infection
err2024-11-06
err0
errOAAI
errSayyad, Zuberwasim; Acharya, Dhiraj; Gack, Michaela U.
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ISGylation of the SARS-CoV-2 N protein by HERC5 impedes N oligomerization and thereby viral RNA synthesis
err2024-09-17
err1
errOAAI
errZhu, Junji; Liu, GuanQun; Sayyad, Zuberwasim; Goins, Christopher M.; Stauffer, Shaun R.; Gack, Michaela U.
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Inherited C-terminal TREX1 variants disrupt homology-directed repair to cause senescence and DNA damage phenotypes in Drosophila, mice, and humans
err2024-06-01
err2
errOAAI
errChauvin, Samuel D.; Ando, Shoichiro; Holley, Joe A.; Sugie, Atsushi; Zhao, Fang R.; Poddar, Subhajit; Kato, Rei; Miner, Cathrine A.; Nitta, Yohei; Krishnamurthy, Siddharth R.; Saito, Rie; Ning, Yue; Hatano, Yuya; Kitahara, Sho; Koide, Shin; Stinson, W. Alexander; Fu, Jiayuan; Surve, Nehalee; Kumble, Lindsay; Qian, Wei; Polishchuk, Oleksiy; Andhey, Prabhakar S.; Chiang, Cindy; Liu, Guanqun; Colombeau, Ludovic; Rodriguez, Raphael; Manel, Nicolas; Kakita, Akiyoshi; Artyomov, Maxim N.; Schultz, David C.; Coates, P. Toby; Roberson, Elisha D. O.; Belkaid, Yasmine; Greenberg, Roger A.; Cherry, Sara; Gack, Michaela U.; Hardy, Tristan; Onodera, Osamu; Kato, Taisuke; Miner, Jonathan J.
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ADAM9 promotes type I interferon-mediated innate immunity during encephalomyocarditis virus infection
err2024-05-16
err0
errOAAI
errBazzone, Lindsey E.; Zhu, Junji; King, Michael; Liu, GuanQun; Guo, Zhiru; MacKay, Christopher R.; Kyawe, Pyae P.; Qaisar, Natasha; Rojas-Quintero, Joselyn; Owen, Caroline A.; Brass, Abraham L.; McDougall, William; Baer, Christina E.; Cashman, Timothy; Trivedi, Chinmay M.; Gack, Michaela U.; Finberg, Robert W.; Kurt-Jones, Evelyn A.
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Hijacking of nucleotide biosynthesis and deamidation-mediated glycolysis by an oncogenic herpesvirus
err2024-02-16
err3
errOAAI
errWan, Quanyuan; Tavakoli, Leah; Wang, Ting-Yu; Tucker, Andrew J.; Zhou, Ruiting; Liu, Qizhi; Feng, Shu; Choi, Dongwon; He, Zhiheng; Gack, Michaela U.; Zhao, Jun
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Atypical activation of the RNA sensor MDA5 by hepatitis C virus
err2023-12-15
err0
PREAI
errChakraborty, Surajit; Zhu, Junji; Gack, Michaela U.
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ISG15: its roles in SARS-CoV-2 and other viral infections
err2023-12-01
err10
errOAAI
errSarkar, Lucky; Liu, Guanqun; Gack, Michaela U.
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CSNK2 suppresses autophagy by activating FLN-NHL-containing TRIM proteins
errAUTOPHAGY
IF14.3
err2023-11-17
err6
errOAAI
errHoenigsperger, Helene; Koepke, Lennart; Acharya, Dhiraj; Hunszinger, Victoria; Freisem, Dennis; Grenzner, Alexander; Wiese, Sebastian; Kirchhoff, Frank; Gack, Michaela U.; Sparrer, Konstantin M. J.
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Viral evasion of the interferon response at a glance
err2023-06-21
err16
errOAAI
errZhu, Junji; Chiang, Cindy; Gack, Michaela U.
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A viral pan-end RNA element and host complex define a SARS-CoV-2 regulon
err2023-06-09
err7
errOAAI
errKhan, Debjit; Terenzi, Fulvia; Liu, GuanQun; Ghosh, Prabar K.; Ye, Fengchun; Nguyen, Kien; China, Arnab; Ramachandiran, Iyappan; Chakraborty, Shruti; Stefan, Jennifer; Khan, Krishnendu; Vasu, Kommireddy; Dong, Franklin; Willard, Belinda; Karn, Jonathan; Gack, Michaela U.; Fox, Paul L.
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The RNA polymerase III-RIG-I axis in antiviral immunity and inflammation
err2023-06-01
err6
errOAAI
errNaesens, Leslie; Haerynck, Filomeen; Gack, Michaela U.
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Virology under the Microscope-a Call for Rational Discourse
errMSPHERE
IF3.1
err2023-04-20
err5
errOAAI
errGoodrum, Felicia; Lowen, Anice C.; Lakdawala, Seema; Alwine, James; Casadevall, Arturo; Imperiale, Michael J.; Atwood, Walter; Avgousti, Daphne; Baines, Joel; Banfield, Bruce; Banks, Lawrence; Bhaduri-McIntosh, Sumita; Bhattacharya, Deepta; Blanco-Melo, Daniel; Bloom, David; Boon, Adrianus; Boulant, Steeve; Brandt, Curtis; Broadbent, Andrew; Brooke, Christopher; Cameron, Craig; Campos, Samuel; Caposio, Patrizia; Chan, Gary; Cliffe, Anna; Coffin, John; Collins, Kathleen; Damania, Blossom; Daugherty, Matthew; Debbink, Kari; DeCaprio, James; Dermody, Terence; Dikeakos, Jimmy; DiMaio, Daniel; Dinglasan, Rhoel; Duprex, W. Paul; Dutch, Rebecca; Elde, Nels; Emerman, Michael; Enquist, Lynn; Fane, Bentley; Fernandez-Sesma, Ana; Flenniken, Michelle; Frappier, Lori; Frieman, Matthew; Frueh, Klaus; Gack, Michaela; Gaglia, Marta; Gallagher, Tom; Galloway, Denise; Garcia-Sastre, Adolfo; Geballe, Adam; Glaunsinger, Britt; Goff, Stephen; Greninger, Alexander; Hancock, Meaghan; Harris, Eva; Heaton, Nicholas; Heise, Mark; Heldwein, Ekaterina; Hogue, Brenda; Horner, Stacy; Hutchinson, Edward; Hyser, Joseph; Jackson, William; Kalejta, Robert; Kamil, Jeremy; Karst, Stephanie; Kirchhoff, Frank; Knipe, David; Kowalik, Timothy; Lagunoff, Michael; Laimins, Laimonis; Langlois, Ryan; Lauring, Adam; Lee, Benhur; Leib, David; Liu, Shan-Lu; Longnecker, Richard; Lopez, Carolina; Luftig, Micah; Lund, Jennifer; Manicassamy, Balaji; McFadden, Grant; McIntosh, Michael; Mehle, Andrew; Miller, W. Allen; Mohr, Ian; Moody, Cary; Moorman, Nathaniel; Moscona, Anne; Mounce, Bryan; Munger, Joshua; Munger, Karl; Murphy, Eain; Naghavi, Mojgan; Nelson, Jay; Neufeldt, Christopher; Nikolich, Janko; O'Connor, Christine; Ono, Akira; Orenstein, Walter; Ornelles, David; Ou, Jing-Hsiung; Parker, John; Parrish, Colin; Pekosz, Andrew; Pellett, Philip; Pfeiffer, Julie; Plemper, Richard; Polyak, Stephen; Purdy, John; Pyeon, Dohun; Quinones-Mateu, Miguel; Renne, Rolf; Rice, Charles; Schoggins, John; Roller, Richard; Russell, Charles; Sandri-Goldin, Rozanne; Sapp, Martin; Schang, Luis; Schmid, Scott; Schultz-Cherry, Stacey; Semler, Bert; Shenk, Thomas; Silvestri, Guido; Simon, Viviana; Smith, Gregory; Smith, Jason; Spindler, Katherine; Stanifer, Megan; Subbarao, Kanta; Sundquist, Wesley; Suthar, Mehul; Sutton, Troy; Tai, Andrew; Tarakanova, Vera; TenOever, Benjamin; Tibbetts, Scott; Tompkins, Stephen; Toth, Zsolt; van Doorslaer, Koenraad; Vignuzzi, Marco; Wallace, Nicholas; Walsh, Derek; Weekes, Michael; Weinberg, Jason; Weitzman, Matthew; Weller, Sandra; Whelan, Sean; White, Elizabeth; Williams, Bryan; Wobus, Christiane; Wong, Scott; Yurochko, Andrew
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