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Rachel R Caspi

national institutes of health (nih) - usa

77H-index
549Paper Count
2.0WCitation Count
Published Papers 126
Publication Date
Gut microbiota drive autoimmunity to neuroretina in a humanized gnotobiotic mouse model of spontaneous autoimmune uveitis
err2025-11-01
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PREAI
errZhang, Amy; Horai, Reiko; Jittayasothorn, Yingyos; Badger, Jonathan; Gupta, Akriti; Murphy, Caitlin Elizabeth; Arunkumar, Samyuktha; Nagarajan, Vijayaraj; Shi, Guangpu; Palmer, Robert; Yuan, Wuxing; O'huigin, Colm S.; Honda, Kenya; Caspi, Rachel
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Ocular immune privilege in action: the living eye imposes unique regulatory and anergic gene signatures on uveitogenic T cells
err2025-11-01
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PREAI
errPeng, Zixuan; Mattapallil, Mary J.; Horai, Reiko; Nagarajan, Vijayaraj; Jittayasothorn, Yingyos; Caspi, Rachel R.
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TLR2 supports γδ T cell IL-17A response to ocular surface commensals by metabolic reprogramming
err2025-09-11
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PREAI
errZhu, Wenjie; Xu, Xiaoyan; Nagarajan, Vijayaraj; Guo, Jing; Gupta, Akriti; Peng, Zixuan; Zhang, Amy; Liu, Jie; Mattapallil, Mary J.; Jittayasothorn, Yingyos; Horai, Reiko; Belkaid, Yasmine; Constantinides, Michael G.; St Leger, Anthony J.; Caspi, Rachel R.
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SCassist: an AI based workflow assistant for single-cell analysis
err2025-08-01
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errOAAI
errNagarajan, Vijayaraj; Shi, Guangpu; Arunkumar, Samyuktha; Liu, Chunhong; Gopalakrishnan, Jaanam; Nath, Pulak R.; Jang, Junseok; Caspi, Rachel R.
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Matrix molecules associated with both regulation of inflammation and pathogenic outcomes associated with the surface of the lens in the eyes of EAU mice
err2025-07-18
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PREAI
errPhuong M. Le; JodiRae DeDreu; Mary J. Mattapallil; Rachel R. Caspi; Ryan Tomlinson; Mary Ann Stepp; A. Sue Menko
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Single-cell profiling identifies a CD8bright CD244bright Natural Killer cell subset that reflects disease activity in HLA-A29-positive birdshot chorioretinopathy
err2024-07-31
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errOAAI
errNath, Pulak R.; Maclean, Mary; Nagarajan, Vijay; Lee, Jung Wha; Yakin, Mehmet; Kumar, Aman; Nadali, Hadi; Schmidt, Brian; Kaya, Koray D.; Kodati, Shilpa; Young, Alice; Caspi, Rachel R.; Kuiper, Jonas J. W.; Sen, H. Nida
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Ebola virus-induced eye sequelae: a murine model for evaluating glycoprotein-targeting therapeutics
err2024-06-01
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errOAAI
errLee, Ha-Na; Xu, Biying; Lewkowicz, Aaron P.; Engel, Kaliroi; Kelley-Baker, Logan; McWilliams, Ian L.; Ireland, Derek D. C.; Kielczewski, Jennifer L.; Li, Jinbo; Fariss, Robert N.; Campos, Mercedes M.; Baum, Alina; Kyratsous, Christos; Pascal, Kristen; Chan, Chi-Chao; Caspi, Rachel R.; Manangeeswaran, Mohanraj; Verthelyi, Daniela
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Tracking the role of Aire in immune tolerance to the eye with a TCR transgenic mouse model
err2024-01-23
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errOAAI
errYin, Mianmian; Smith, Jennifer A.; Chou, Marissa; Chan, Jackie; Jittayasothorn, Yingyos; Gould, Douglas B.; Caspi, Rachel R.; Anderson, Mark S.; Defranco, Anthony L.
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A CD6-targeted antibody-drug conjugate as a potential therapy for T cell-mediated disorders
err2023-12-08
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errOAAI
errZhang, Lingjun; Luo, Liping; Chen, Jin Y.; Singh, Rupesh; Baldwin, William M., III; Fox, David A.; Lindner, Daniel J.; Martin, Daniel F.; Caspi, Rachel R.; Lin, Feng
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Too Much of a Good Thing: Extended Duration of Gut Microbiota Depletion Reverses Protection From Experimental Autoimmune Uveitis
err2023-11-29
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errOAAI
errSalvador, Ryan; Horai, Reiko; Zhang, Amy; Jittayasothorn, Yingyos; Tang, Jihong; Gupta, Akriti; Nagarajan, Vijayaraj; Caspi, Rachel R.
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Effects of a Small-Molecule Perforin Inhibitor in a Mouse Model of CD8 T Cell-Mediated Neuroinflammation
err2023-07-01
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errOAAI
errGonzalez-Fierro, Carmen; Fonte, Coralie; Dufourd, Eloise; Cazaentre, Vincent; Aydin, Sidar; Engelhardt, Britta; Caspi, Rachel R.; Xu, Biying; Martin-Blondel, Guillaume; Spicer, Julie A.; Trapani, Joseph A.; Bauer, Jan; Liblau, Roland S.; Bost, Chloe
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Towards molecular mechanisms for pathogenic Th17 cell differentiation in ocular autoimmunity
err2023-05-01
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errOAAI
errBass, Victor; Mattapallil, Mary J.; Xu, Biying; Caspi, Rachel; Shih, Han-Yu
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Contact lens-induced corneal parainflammation involving Ly6G+cell infiltration requires IL-17A and γ8 T cells
err2023-04-01
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errOAAI
errDatta, Ananya; Truong, Tiffany; Lee, Ji Hyun; Horneman, Hart; Flandrin, Orneika; Lee, Justin; Kumar, Naren G.; Caspi, Rachel R.; Evans, David J.; Fleiszig, Suzanne M. J.
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Mucosal immunology of the ocular surface
err2022-11-01
err43
errOAAI
errde Paiva, Cintia S.; St Leger, Anthony J.; Caspi, Rachel R.
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CDCP1 regulates retinal pigmented epithelial barrier integrity for the development of experimental autoimmune uveitis
err2022-09-22
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errOAAI
errZhang, Lingjun; Borjini, Nozha; Lun, Yu; Parab, Sweta; Asonye, Gospel; Singh, Rupesh; Bell, Brent A.; Bonilha, Vera L.; Ivanov, Andrei; Fox, David A.; Caspi, Rachel; Lin, Feng
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Regulated Tristetraprolin Overexpression Dampens the Development and Pathogenesis of Experimental Autoimmune Uveitis
err2021-01-25
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errOAAI
errXu, Biying; Tang, Jihong; Lyu, Cancan; Wandu, Wambui S.; Stumpo, Deborah J.; Mattapallil, Mary J.; Horai, Reiko; Gery, Igal; Blackshear, Perry J.; Caspi, Rachel R.
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Autoimmunity to neuroretina in the concurrent absence of IFN-γ and IL-17A is mediated by a GM-CSF-driven eosinophilic inflammation
err2020-11-01
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errOAAI
errBing, So Jin; Silver, Phyllis B.; Jittayasothorn, Yingyos; Mattapallil, Mary J.; Chan, Chi-Chao; Horai, Reiko; Caspi, Rachel R.
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T cell-intrinsic role for Nod2 in protection against Th17-mediated uveitis
err2020-10-26
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errOAAI
errNapier, Ruth J.; Lee, Ellen J.; Davey, Michael P.; Vance, Emily E.; Furtado, Joao M.; Snow, Paige E.; Samson, Kimberly A.; Lashley, Sydney J.; Brown, Brieanna R.; Horai, Reiko; Mattapallil, Mary J.; Xu, Biying; Callegan, Michelle C.; Uebelhoer, Luke S.; Lancioni, Christina L.; Vehe, Richard K.; Binstadt, Bryce A.; Smith, Justine R.; Caspi, Rachel R.; Rosenzweig, Holly L.
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Noel R. Rose 1927-2020
err2020-09-07
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errOAAI
errScott, David W.; Caspi, Rachel R.; Moudgil, Kamal D.
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The Cytokine IL-17A Limits Th17 Pathogenicity via a Negative Feedback Loop Driven by Autocrine Induction of IL-24
errIMMUNITY
IF26.3
err2020-08-01
err122
errOAAI
errChong, Wai Po; Mattapallil, Mary J.; Raychaudhuri, Kumarkrishna; Bing, So Jin; Wu, Sihan; Zhong, Yajie; Wang, WeiWei; Chen, Zilin; Silver, Phyllis B.; Jittayasothorn, Yingyos; Chan, Chi-Chao; Chen, Jun; Horai, Reiko; Caspi, Rachel R.
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