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MISTRG6kitW41: Enhanced Engraftment in a Cytokine Humanized Patient-Derived Xenotransplantation Mouse Model Baassiri, Amro; Maziarz, Jamie; Blackburn, Holly Nicole; Maul-Newby, Hannah; Vanoudenhove, Jennifer; Zhang, Xuan; Matthews, Martin; Paul, Sambuddha; Liu, Wei; Sefik, Esen; Salomonis, Nathan; Grimes, H. Leighton; Flavell, Richard; Halene, Stephanie Share Save
The human CD47 checkpoint is targeted by an immunosuppressive Aedes aegypti salivary factor to enhance arboviral skin infectivity Marin-Lopez, Alejandro; Huck, John D.; Esterly, Allen T.; Azcutia, Veronica; Rosen, Connor; Garcia-Milian, Rolando; Sefik, Esen; Vidal-Pedrola, Gemma; Raduwan, Hamidah; Chen, Tse-Yu; Arora, Gunjan; Halene, Stephanie; Shaw, Albert C.; Palm, Noah W.; Flavell, Richard A.; Parkos, Charles A.; Thangamani, Saravanan; Ring, Aaron M.; Fikrig, Erol Share Save
Gene trajectory inference for single-cell data by optimal transport metrics Qu, Rihao; Cheng, Xiuyuan; Sefik, Esen; Stanley, Jay S.; Landa, Boris; Strino, Francesco; Platt, Sarah; Garritano, James; Odell, Ian D.; Coifman, Ronald; Flavell, Richard A.; Myung, Peggy; Kluger, Yuval Share Save
IL-6 trans-signaling in a humanized mouse model of scleroderma Odell, Ian D.; Agrawal, Kriti; Sefik, Esen; Odell, Anahi V.; Caves, Elizabeth; Kirkiles-Smith, Nancy C.; Horsley, Valerie; Hinchcliff, Monique; Pober, Jordan S.; Kluger, Yuval; Flavell, Richard A. Share Save
Autologous humanized PDX modeling for immuno-oncology recapitulates features of the human tumor microenvironment Chiorazzi, Michael; Martinek, Jan; Krasnick, Bradley; Zheng, Yunjiang; Robbins, Keenan J.; Qu, Rihao; Kaufmann, Gabriel; Skidmore, Zachary; Juric, Melani; Henze, Laura A.; Brosecke, Frederic; Adonyi, Adam; Zhao, Jun; Shan, Liang; Sefik, Esen; Mudd, Jacqueline; Bi, Ye; Goedegebuure, S. Peter; Griffith, Malachi; Griffith, Obi; Oyedeji, Abimbola; Fertuzinhos, Sofia; Garcia-Milian, Rolando; Boffa, Daniel; Detterbeck, Frank; Dhanasopon, Andrew; Blasberg, Justin; Judson, Benjamin; Gettinger, Scott; Politi, Katerina; Kluger, Yuval; Palucka, Karolina; Fields, Ryan C.; Flavell, Richard A. Share Save
IL-7R licenses a population of epigenetically poised memory CD8+T cells with superior antitumor efficacy that are critical for melanoma memory Micevic, Goran; Daniels, Andrew; Flem-Karlsen, Karine; Park, Koonam; Talty, Ronan; McGeary, Meaghan; Mirza, Haris; Blackburn, Holly N.; Sefik, Esen; Cheung, Julie F.; Hornick, Noah I.; Aizenbud, Lilach; Joshi, Nikhil S.; Kluger, Harriet; Iwasaki, Akiko; Bosenberg, Marcus W.; Flavell, Richard A. Share Save
Regulatory T cells in the face of the intestinal microbiota Ramanan, Deepshika; Pratama, Alvin; Zhu, Yangyang; Venezia, Olivia; Sassone-Corsi, Martina; Chowdhary, Kaitavjeet; Galvan-Pena, Silvia; Sefik, Esen; Brown, Chrysothemis; Gelineau, Adelaide; Mathis, Diane; Benoist, Christophe Share Save
A Treg-specific long noncoding RNA maintains immune-metabolic homeostasis in aging liver Ding, Chenbo; Yu, Zhibin; Sefik, Esen; Zhou, Jing; Kaffe, Eleanna; Wang, Gaoyang; Li, Bin; Flavell, Richard A.; Hu, Weiguo; Ye, Youqiong; Li, Hua-Bing Share Save
Autologous humanized PDX modeling for immuno-oncology recapitulates the human tumor microenvironment Chiorazzi, Michael; Martinek, Jan; Krasnick, Bradley; Zheng, Yunjiang; Robbins, Keenan; Qu, Rihao; Kaufmann, Gabriel; Skidmore, Zachary; Henze, Laura; Brosecke, Frederic; Adonyi, Adam; Zhao, Jun; Shan, Liang; Sefik, Esen; Mudd, Jacqueline; Bi, Ye; Goedegebuure, S. Peter; Griffith, Malachi; Griffith, Obi; Oyedeji, Abimbola; Fertuzinhos, Sofia; Garcia-Milian, Roland; Boffa, Daniel; Detterbeck, Frank; Dhanasopon, Andrew; Blasberg, Justin; Judson, Benjamin; Gettinger, Scott; Politi, Katerina; Kluger, Yuval; Palucka, A. Karolina; Fields, Ryan; Flavell, Richard A. Share Save
Human neutrophil development and functionality are enabled in a humanized mouse model Zheng, Yunjiang; Sefik, Esen; Astle, John; Karatepe, Kutay; OZ, Hasan H.; Solis, Angel G.; Jackson, Ruaidhri; Luo, Hongbo R.; Bruscia, Emanuela M.; Halene, Stephanie; Shan, Liang; Flavell, Richard A. Share Save
RNA m6A demethylase ALKBH5 regulates the development of γδ T cells Ding, Chenbo; Xu, Hao; Yu, Zhibin; Roulis, Manolis; Qu, Rihao; Zhou, Jing; Oh, Joonseok; Crawford, Jason; Gao, Yimeng; Jackson, Ruaidhri; Sefik, Esen; Li, Simiao; Wei, Zheng; Skadow, Mathias; Yin, Zhinan; Ouyang, Xinshou; Wang, Lei; Zou, Qiang; Su, Bing; Hu, Weiguo; Flavell, Richard A.; Li, Hua-Bing Share Save
A humanized mouse model of chronic COVID-19 Sefik, Esen; Israelow, Benjamin; Mirza, Haris; Zhao, Jun; Qu, Rihao; Kaffe, Eleanna; Song, Eric; Halene, Stephanie; Meffre, Eric; Kluger, Yuval; Nussenzweig, Michel; Wilen, Craig B.; Iwasaki, Akiko; Flavell, Richard A. Share Save
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Tissue-resident memory T cell reactivation by diverse antigen-presenting cells imparts distinct functional responses Low, Jun Siong; Farsakoglu, Yagmur; Vesely, Maria Carolina Amezcua; Sefik, Esen; Kelly, Joseph B.; Harman, Christian C. D.; Jackson, Ruaidhri; Shyer, Justin A.; Jiang, Xiaodong; Cauley, Linda S.; Flavell, Richard A.; Kaech, Susan M. Share Save
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