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Todd M. Brusko

university of florida

59H-index
269Paper Count
1.2WCitation Count
Published Papers 139
Publication Date
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Imaging mass cytometry reveals functional and immunological changes during type 1 diabetes progression in human pancreata
errNature Metabolism
IF20.8
err2026-07-02
err0
errOAAI
errNathan Steenbuck; Nicolas Damond; Stefanie Engler; Irina Kusmartseva; Amanda L. Posgai; Denise M. Drotar; MacKenzie D. Williams; Natalie de Souza; Todd M. Brusko; Maigan A. Brusko; Clive H. Wasserfall; Mark A. Atkinson; Bernd Bodenmiller
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Distinct transcription factors control tissue adaptation and effector function in infant and adult memory T cells
errNature Immunology
IF27.6
err2026-06-02
err0
errOAAI
errPeter A. Szabo; Hanna M. Levitin; Siddhi Nargund; Thomas J. Connors; David Chen; Jenny Jin; Puspa Thapa; Rebecca Guyer; Daniel P. Caron; Joshua I. Gray; Rei Matsumoto; Masaru Kubota; Maigan Brusko; Todd M. Brusko; Donna L. Farber; Peter A. Sims
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errSave
Beta cell–targeted PD-1 agonist inhibits cell-mediated autoimmunity in pancreas tissue slices
errScience Advances
IF12.5
err2026-04-01
err0
errOAAI
errMatthew W. Becker; Matthew E. Brown; Katherine Wiseman; Ana Laura Chiodetti; Mollie K. Huber; Alexandra E. Cuaycal; Pumin Sintara; Sandra M. Ferreira; Dylan Smurlick; Jessie M. Barra; Andrew M. Ladd; Denise M. Drotar; Mark A. Atkinson; Peter Weber; Hussein Al-Mossawi; Holger A. Russ; Tara M. Mahon; Todd M. Brusko; Giovanna Bossi; Edward A. Phelps
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errSave
Spatial transcriptomics from pancreas and local draining lymph node tissue reveals a lymphotoxin-β signature in human type 1 diabetes
errCell Reports
IF6.9
err2026-03-23
err0
errOAAI
errMiguel A. Medina-Serpas; Maigan Brusko; Gregory J. Golden; Martha Campbell-Thompson; Trevor Rogers; Shay Reardon; Amanda L. Posgai; Rhonda Bacher; Eline T. Luning Prak; Chengyang Liu; Klaus H. Kaestner; Ali Naji; Michael R. Betts; Lauren M. McIntyre; Mark A. Atkinson; Todd M. Brusko
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errSave
Epithelial-Mesenchymal Transition Activates YAP to Drive Malignant Progression and Immune Evasion
errCancers
IF4.4
err2026-03-03
err0
errOAAI
errXi Huang; Mingyan Zhang; Alexander D. Pearce; Matthew D. Gibbons; Dan Jin; Lu Li; Dongxin Hu; Renbin Liu; Mu Yu; Ming Tan; Jia Chang; Jixin Dong; Mingyi Xie; Weizhou Zhang; Lizi Wu; Catherine Flores; Jörg Bungert; Todd M. Brusko; Jianrong Lu
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errSave
Identification of a type 1 diabetes–associated T cell receptor repertoire signature from the human peripheral blood
errScience Advances
IF12.5
err2026-02-13
err0
errOAAI
errPuneet Rawat; Melanie R. Shapiro; Leeana D. Peters; Michael Widrich; Koshlan Mayer-Blackwell; Keshav Motwani; Milena Pavlović; Ghadi al Hajj; Amanda L. Posgai; Chakravarthi Kanduri; Giulio Isacchini; Maria Chernigovskaya; Lonneke Scheffer; Kartik Motwani; Leandro Octavio Balzano-Nogueira; Camryn M. Pettenger-Willey; Sebastiaan Valkiers; Laura M. Jacobsen; Michael J. Haller; Desmond A. Schatz; Clive H. Wasserfall; Ryan O. Emerson; Andrew J. Fiore-Gartland; Mark A. Atkinson; Günter Klambauer; Geir Kjetil Sandve; Victor Greiff; Todd M. Brusko
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errSave
Human stem cell-derived β cells expressing an optimized CD155 reduce cytotoxic immune cell function for application in type 1 diabetes
errScience Advances
IF12.5
err2025-11-07
err0
PREAI
errMatthew E. Brown; Jessie M. Barra; Marcus R. Pina; James Proia; Todd M. Brusko; Holger A. Russ
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errSave
Regulatory T cells modulate presentation of autoantigens via pMHCII removal
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errAkkaya, Billur; Singh, Vishal; Akkaya, Munir; Brusko, Todd M.; Shevach, Ethan M.
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errSave
Overexpression of CD155 in human stem cell-derived β-cells diminishes autoreactive T cell responses
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errBarra, Jessie M.; Brown, Matthew E.; Pina, Marcus R.; Proia, James; Brusko, Todd M.; Russ, Holger
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errSave
Asynchronous aging and turnover of human circulating and tissue-resident memory T cells across sites
errImmunity
IF26.3
err2025-07-29
err0
PREAI
errNora Lam; J. Carlos Angel; Bruce A. Buchholz; YoonSeung Lee; Stuart P. Weisberg; Brea H. Brown; Julia Davis-Porada; Daniel P. Caron; Isaac J. Jensen; Peter A. Szabo; Basak B. Ural; Steven B. Wells; Masaru Kubota; Rei Matsumoto; Maigan Brusko; Todd M. Brusko; Chao Lu; Andrew J. Yates; Donna L. Farber
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errSave
Immune perturbations in human pancreas lymphatic tissues prior to and after type 1 diabetes onset
errNATURE COMMUNICATIONS
IF15.7
err2025-05-18
err0
errOAAI
errGolden, Gregory J.; Wu, Vincent H.; Hamilton, Jacob T.; Amses, Kevin R.; Shapiro, Melanie R.; Japp, Alberto Sada; Liu, Chengyang; Pampena, M. Betina; Kuri-Cervantes, Leticia; Knox, James J.; Gardner, Jay S.; Atkinson, Mark A.; Brusko, Todd M.; Prak, Eline T. Luning; Kaestner, Klaus H.; Naji, Ali; Betts, Michael R.
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errSave
Serological markers of exocrine pancreatic function are differentially informative for distinguishing individuals progressing to type 1 diabetes
errBMJ OPEN DIABETES RESEARCH & CARE
IF4.1
err2025-01-04
err0
errOAAI
errWilliams, MacKenzie D.; Grace, Catherine Ramsey; Posgai, Amanda L.; Mcgrail, Kieran M.; Brusko, Maigan A.; Haller, Michael J.; Jacobsen, Laura; Schatz, Desmond; Brusko, Todd M.; Atkinson, Mark; Bacher, Rhonda; Wasserfall, Clive H.
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errSave
Leveraging artificial intelligence and machine learning to accelerate discovery of disease-modifying therapies in type 1 diabetes
errDIABETOLOGIA
IF10.2
err2024-12-19
err0
errOAAI
errShapiro, Melanie R.; Tallon, Erin M.; Brown, Matthew E.; Posgai, Amanda L.; Clements, Mark A.; Brusko, Todd M.
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errSave
Characteristics of autoantibody-positive individuals without high-risk HLA-DR4-DQ8 or HLA-DR3-DQ2 haplotypes
errDIABETOLOGIA
IF10.2
err2024-12-13
err0
errOAAI
errRedondo, Maria J.; Cuthbertson, David; Steck, Andrea K.; Herold, Kevan C.; Oram, Richard; Atkinson, Mark; Brusko, Todd M.; Parikh, Hemang M.; Krischer, Jeffrey P.; Onengut-Gumuscu, Suna; Rich, Stephen S.; Sosenko, Jay M.
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errSave
Inhibition of CD226 co-stimulation suppresses diabetes development in the NOD mouse by augmenting regulatory T cells and diminishing effector T cell function
errDIABETOLOGIA
IF10.2
err2024-12-05
err0
errOAAI
errBrown, Matthew E.; Thirawatananond, Puchong; Peters, Leeana D.; Kern, Elizabeth J.; Vijay, Sonali; Sachs, Lindsey K.; Posgai, Amanda L.; Brusko, Maigan A.; Shapiro, Melanie R.; Mathews, Clayton E.; Bacher, Rhonda; Brusko, Todd M.
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errSave
Unique lymphocyte transcriptomic profiles in septic patients with chronic critical illness
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2024-12-03
err0
errOAAI
errBarrios, Evan L.; Balzano-Nogueira, Leandro; Polcz, Valerie E.; Rodhouse, Christine; Leary, Jack R.; Darden, Dijoia B.; Rincon, Jaimar C.; Dirain, Marvin L.; Ungaro, Ricardo; Nacionales, Dina C.; Larson, Shawn D.; Sharma, Ashish; Upchurch, Gilburt; Wallet, Shannon M.; Brusko, Todd M.; Loftus, Tyler J.; Mohr, Alicia M.; Maile, Robert; Bacher, Rhonda; Cai, Guoshuai; Kladde, Michael P.; Mathews, Clayton E.; Moldawer, Lyle L.; Brusko, Maigan A.; Efron, Philip A.
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errSave
The Type 1 Diabetes T Cell Receptor and B Cell Receptor Repository in the AIRR Data Commons: a practical guide for access, use and contributions through the Type 1 Diabetes AIRR Consortium
errDIABETOLOGIA
IF10.2
err2024-10-29
err0
errOAAI
errHanna, Stephanie J.; Bonami, Rachel H.; Corrie, Brian; Westley, Monica; Posgai, Amanda L.; Prak, Eline T. Luning; Breden, Felix; Michels, Aaron W.; Brusko, Todd M.
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errSave
Low Morning Cortisol in Early Life Associated with Increased Risk of Islet Autoimmunity
errDIABETES
IF7.5
err2024-06-14
err0
PREAI
errVehik, Kendra; Lynch, Kristian F.; Parikh, Hemang M.; Lernmark, Ake; Rewers, Marian; McIndoe, Richard; Toppari, Jorma; Ziegler, Anette-Gabriele; Akolkar, Beena; Hagopian, William; Brusko, Todd M.; Krischer, Jeffrey; Roth, Roswith L.; Johnson, Suzanne B.
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errSave
Curation of an AI-Ready Dataset Using Domain-Informed Features Derived from Type 1 Diabetes TrialNet Studies
errDIABETES
IF7.5
err2024-06-14
err0
PREAI
errTallon, Erin M.; Shapiro, Melanie R.; Waghmode, Amey Shrikrishna; Merritt, Ryan; Wasserfall, Clive; Bacher, Rhonda; Lockee, Brent; Vandervelden, Craig; Panfil, Kelsey; Moore, Wayne V.; Atkinson, Mark A.; Brusko, Todd M.; Clements, Mark A.
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errSave
Postprandial C-Peptide (pCP) in Provider-Diagnosed Pediatric Type 1 Diabetes (T1D) and Type 2 Diabetes (T2D)
errDIABETES
IF7.5
err2024-06-14
err0
PREAI
errRedondo, Maria J.; Harrall, Kylie K.; Bird, Sarah M.; Tosur, Mustafa; Uysal, Serife; Siller, Alejandro F.; Velasquez, Horacio J.; Muir, Andrew; Vehik, Kendra; Brusko, Todd M.; Atkinson, Mark A.; Dabelea, Dana; Hagopian, William; Oram, Richard A.
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Research Directions

No research directions
Co-authors
Cooperation Journals
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Stephen S. Rich
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Jeffrey A. Bluestone
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John A. Todd
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