Not logged in Exploration of BMI and circulating metabolic factors as predictors of metformin benefit in CCTG MA.32 Pamela J Goodwin, MD; Marguerite Ennis, PhD; Bingshu E Chen, PhD; Karen A Gelmon, MD; Timothy J Whelan, MD; Jennifer A Ligibel, MD; Alastair M Thompson, MBChB MD; Lois E Shepherd, MD; Wendy R Parulekar, MD; Ryan Dowling, PhD; Vuk Stambolic, PhD Share Save
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Insulin receptor loss impairs mammary tumorigenesis in mice Podmore, Lauren; Poloz, Yekaterina; Iorio, Catherine; Mouaaz, Samar; Nixon, Kevin; Smirnov, Petr; Mcdonnell, Brianna; Lam, Sonya; Zhang, Bowen; Tharmapalan, Pirashaanthy; Sarkar, Soumili; Vyas, Foram; Ennis, Marguerite; Dowling, Ryan; Stambolic, Vuk Share Save
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Machine learning-enabled cancer diagnostics with widefield polarimetric second-harmonic generation microscopy Mirsanaye, Kamdin; Uribe Castano, Leonardo; Kamaliddin, Yasmeen; Golaraei, Ahmad; Augulis, Renaldas; Kontenis, Lukas; Done, Susan J.; Zurauskas, Edvardas; Stambolic, Vuk; Wilson, Brian C.; Barzda, Virginijus Share Save
Effect of Metformin vs Placebo on Invasive Disease-Free Survival in Patients With Breast Cancer The MA.32 Randomized Clinical Trial Goodwin, Pamela J.; Chen, Bingshu E.; Gelmon, Karen A.; Whelan, Timothy J.; Ennis, Marguerite; Lemieux, Julie; Ligibel, Jennifer A.; Hershman, Dawn L.; Mayer, Ingrid A.; Hobday, Timothy J.; Bliss, Judith M.; Rastogi, Priya; Rabaglio-Poretti, Manuela; Mukherjee, Som D.; Mackey, John R.; Abramson, Vandana G.; Oja, Conrad; Wesolowski, Robert; Thompson, Alastair M.; Rea, Daniel W.; Stos, Paul M.; Shepherd, Lois E.; Stambolic, Vuk; Parulekar, Wendy R. Share Save
CCTGMA.32, a phase III randomized double-blind placebo controlled adjuvant trial of metformin (MET) vs placebo (PLAC) in early breast cancer (BC): Results of the primary efficacy analysis (clinical trials.gov NCT01101438) Goodwin, Pamela J.; Chen, Bingshu E.; Gelmon, Karen A.; Whelan, Timothy J.; Ennis, Marguerite; Lemieux, Julie; Ligibel, Jennifer A.; Hershman, Dawn L.; Mayer, Ingrid A.; Hobday, Timothy J.; Bliss, Judith M.; Rastogi, Priya; Rabaglio-Poretti, Manuela; Mukherjee, Som D.; Mackey, Robert R.; Abramson, Vandana G.; Oja, Conrad; Wesolowski, Robert; Thompson, Alastair M.; Rea, Daniel W.; Stos, Paul M.; Shepherd, Lois E.; Stambolic, Vuk; Parulekar, Wendy R. Share Save
Cancer Antigen 15-3/Mucin 1 Levels in CCTG MA.32: A Breast Cancer Randomized Trial of Metformin vs Placebo Goodwin, Pamela J.; Dowling, Ryan J. O.; Ennis, Marguerite; Chen, Bingshu E.; Parulekar, Wendy R.; Shepherd, Lois E.; Gelmon, Karen A.; Whelan, Timothy J.; Ligibel, Jennifer A.; Hershman, Dawn L.; Mayer, Ingrid A.; Hobday, Timothy J.; Rastogi, Priya; Rabaglio-Poretti, Manuela; Lemieux, Julie; Thompson, Alastair M.; Rea, Daniel W.; Stambolic, Vuk Share Save
Effect of metformin versus placebo on metabolic factors in the MA.32 randomized breast cancer trial Goodwin, Pamela J.; Dowling, Ryan J. O.; Ennis, Marguerite; Chen, Bingshu E.; Parulekar, Wendy R.; Shepherd, Lois E.; Burnell, Margot J.; Vander Meer, Rachel; Molckovsky, Andrea; Gurjal, Anagha; Gelmon, Karen A.; Ligibel, Jennifer A.; Hershman, Dawn L.; Mayer, Ingrid A.; Whelan, Timothy J.; Hobday, Timothy J.; Rastogi, Priya; Rabaglio-Poretti, Manuela; Lemieux, Julie; Thompson, Alastair M.; Rea, Daniel W.; Stambolic, Vuk Share Save
The PTEN and ATM axis controls the G1/S cell cycle checkpoint and tumorigenesis in HER2-positive breast cancer Bassi, Christian; Fortin, Jerome; Snow, Bryan E.; Wakeham, Andrew; Ho, Jason; Haight, Jillian; You-Ten, Annick; Cianci, Emily; Buckler, Luke; Gorrini, Chiara; Stambolic, Vuk; Mak, Tak W. Share Save
Concerted roles of PTEN and ATM in controlling hematopoietic stem cell fitness and dormancy Fortin, Jerome; Bassi, Christian; Ramachandran, Parameswaran; Li, Wanda Y.; Tian, Ruxiao; Zarrabi, Ida; Hill, Graham; Snow, Bryan E.; Haight, Jillian; Tobin, Chantal; Hodgson, Kelsey; Wakeham, Andrew; Stambolic, Vuk; Mak, Tak W. Share Save
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Association between BMI, vitamin D, and estrogen levels in postmenopausal women using adjuvant letrozole: a prospective study Elliott, Mitchell J.; Ennis, Marguerite; Pritchard, Kathleen I.; Townsley, Carol; Warr, Dave; Elser, Christine; Amir, Eitan; Bedard, Philippe L.; Rao, Lakshmi; Stambolic, Vuk; Sridhar, Srikala; Goodwin, Pamela J.; Cescon, David W. Share Save
The Effect of Metformin vs Placebo on Sex Hormones in Canadian Cancer Trials Group MA.32 Pimentel, Isabel; Chen, Bingshu E.; Lohmann, Ana Elisa; Ennis, Marguerite; Ligibel, Jennifer; Shepherd, Lois; Hershman, Dawn L.; Whelan, Timothy; Stambolic, Vuk; Mayer, Ingrid; Hobday, Timothy; Lemieux, Julie; Thompson, Alastair; Rastogi, Priya; Gelmon, Karen; Rea, Daniel; Rabaglio, Manuela; Ellard, Susan; Mates, Mihaela; Bedard, Philippe; Pitre, Lacey; Vandenberg, Theodore; Dowling, Ryan J. O.; Parulekar, Wendy; Goodwin, Pamela J. Share Save
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A phase II randomized clinical trial of the effect of metformin versus placebo on progression-free survival in women with metastatic breast cancer receiving standard chemotherapy Pimentel, Isabel; Lohmann, Ana Elisa; Ennis, Marguerite; Dowling, Ryan J. O.; Cescon, David; Elser, C.; Potvin, K. R.; Haq, R.; Hamm, C.; Chang, Martin C.; Stambolic, Vuk; Goodwin, Pamela J. Share Save
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Opposing effects of NPM1wt and NPM1c mutants on AKT signaling in AML Ren, Zhuo; Shrestha, Mariusz; Sakamoto, Takashi; Melkman, Tali; Meng, Li; Cairns, Rob A.; Zacksenhaus, Eldad; Mak, Tak W.; Stambolic, Vuk; Minden, Mark D.; Wang, Jiance Atom Share Save
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Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs van de Kooij, Bert; Creixell, Pau; van Vlimmerent, Anne; Joughin, Brian A.; Miller, Chad J.; Haider, Nasir; Simpson, Craig D.; Linding, Rune; Stambolic, Vuk; Turk, Benjamin E.; Yaffe, Michael B. Share Save
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