Not logged in Observational and Mendelian randomization studies of plasma sclerostin levels do not provide evidence of cardiovascular adverse effects of sclerostin inhibition Thorolfsdottir, Rosa B.; Sveinbjornsson, Gardar; Hjorleifsson Eldjarn, Grimur; Aegisdottir, Hildur M.; Styrkarsdottir, Unnur; Gretarsdottir, Solveig; Steinthorsdottir, Valgerdur; Tragante, Vinicius; Oddsson, Asmundur; Stefansdottir, Lilja; Thorleifsson, Gudmar; Einarsson, Gudmundur; Helgason, Hannes; Jonsdottir, Andrea B.; Gudjonsson, Sigurjon A.; Ferkingstad, Egil; Brunak, Soren; Brons, Nanna; Bundgaard, Johan S.; Bruun, Mie T.; Erikstrup, Christian; Aagaard, Bitten; Vesterager Pedersen, Ole B.; Sibilitz, Kirstine L.; Sorensen, Erik; Traeholt, Jacob; Ullum, Henrik; Zheng, Chaoqun; Knowlton, Kirk U.; Nadauld, Lincoln D.; Ostrowski, Sisse R.; Bundgaard, Henning; Arnar, David O.; Jonsdottir, Ingileif; Helgadottir, Anna; Thorsteinsdottir, Unnur; Holm, Hilma; Sulem, Patrick; Gudbjartsson, Daniel F.; Stefansson, Kari Share Save
A genome-wide association meta-analysis links hidradenitis suppurativa to common and rare sequence variants causing disruption of the Notch and Wnt/β-catenin signaling pathways Andersen, Rune Kjaersgaard; Stefansdottir, Lilja; Riis, Peter Theut; Halldorsson, Gisli; Ferkingstad, Egil; Oddsson, Asmundur; Walters, Bragi; Olafsdottir, Thorunn A.; Rutsdottir, Gudrun; Zachariae, Claus; Thomsen, Simon Francis; Brodersen, Thortsen; Dinh, Khoa Manh; Knowlton, Kirk U.; Knight, Stacey; Nadauld, Lincoln D.; Banasik, Karina; Brunak, Soren; Hansen, Thomas Folkmann; Hjalgrim, Henrik; Sorensen, Erik; Mikkelsen, Chirstina; Ullum, Henrik; Nyegaard, Mette; Bruun, Mie Topholm; Erikstrup, Christian; Ostrowski, Sisse Rye; Eidsmo, Liv; Saunte, Ditte Marie Lindhardt; Sigurgeirsson, Bardur; Orvar, Kjartar B.; Saemundsdottir, Jona; Melsted, Pall; Norddahl, Gudmundur L.; Sulem, Patrick; Stefansson, Hreinn; Holm, Hilma; Gudbjartsson, Daniel; Thorleifsson, Gudmar; Jonsdottir, Ingileif; Pedersen, Ole Birger Vesterager; Jemec, Gregor Borut Ernst; Stefansson, Kari Share Save
Genome wide association study meta-analysis of 19,487 individuals with mitral valve prolapse identifies 52 novel genomic regions and highlights pro-fibrosis genes Small, Aeron; Berrandou, Takiy-Eddine; Georges, Adrien; Morningstar, Jordan; Huff, Matthew; Yang, Ta-Yu; Lee, Jiwoo; Abner, Erik; Bundgaard, Henning; Wells, Quinn; Wilson, Peter; Cho, Kelly; Rader, Daniel; Ganna, Andrea; Helgadottir, Anna; Holm, Hilma; Stefansson, Kari; Gudbjartsson, Daniel; Vy, Ha My; Rosenberg, Michael; Milan, David; Borger, Michael; Dieterlen, Maja-Theresa; Kontorovich, Amy; Engert, Jamie; Thanassoulis, George; Farber-Eger, Eric; Gignoux, Christopher; Ellinor, Patrick; Peloso, Gina; Norris, Russell; Yu, Mengyao; Bouatia-Naji, Nabila; Natarajan, Pradeep Share Save
Genome-Wide Association Study of Accessory Atrioventricular Pathways Aegisdottir, Hildur M.; Andreasen, Laura; Thorolfsdottir, Rosa B.; Sveinbjornsson, Gardar; Jonsdottir, Andrea B.; Stefansdottir, Lilja; Thorleifsson, Gudmar; Sigurdsson, Asgeir; Halldorsson, Gisli H.; Barc, Julien; Simonet, Floriane; Tragante, Vinicius; Oddsson, Asmundur; Ferkingstad, Egil; Svendsen, Jesper Hastrup; Ghouse, Jonas; Ahlberg, Gustav; Paludan-Mueller, Christian; Hadji-Turdeghal, Katra; Bustamante, Mariana; Ulfarsson, Magnus O.; Helgadottir, Anna; Gretarsdottir, Solveig; Saevarsdottir, Saedis; Jonsdottir, Ingileif; Erikstrup, Christian; Ullum, Henrik; Sorensen, Erik; Brunak, Soren; Jons, Christian; Zheng, Chaoqun; Bezzina, Connie R.; Knowlton, Kirk U.; Nadauld, Lincoln D.; Sulem, Patrick; Ostrowski, Sisse R.; Pedersen, Ole B.; Arnar, David O.; Gudbjartsson, Daniel F.; Olesen, Morten S.; Bundgaard, Henning; Holm, Hilma; Stefansson, Kari Share Save
Gene-based burden tests of rare germline variants identify six cancer susceptibility genes Ivarsdottir, Erna V.; Gudmundsson, Julius; Tragante, Vinicius; Sveinbjornsson, Gardar; Kristmundsdottir, Snaedis; Stacey, Simon N.; Halldorsson, Gisli H.; Magnusson, Magnus I.; Oddsson, Asmundur; Walters, G. Bragi; Sigurdsson, Asgeir; Saevarsdottir, Saedis; Beyter, Doruk; Thorleifsson, Gudmar; Halldorsson, Bjarni V.; Melsted, Pall; Stefansson, Hreinn; Jonsdottir, Ingileif; Sorensen, Erik; Pedersen, Ole B.; Erikstrup, Christian; Bogsted, Martin; Pohl, Mette; Roder, Andreas; Stroomberg, Hein Vincent; Goegenur, Ismail; Hillingso, Jens; Bojesen, Stig E.; Lassen, Ulrik; Hogdall, Estrid; Ullum, Henrik; Brunak, Soren; Ostrowski, Sisse R.; Pedersen, Ole Birger; Sonderby, Ida Elken; Frei, Oleksandr; Djurovic, Srdjan; Havdahl, Alexandra; Moller, Pal; Dominguez-Valentin, Mev; Haavik, Jan; Andreassen, Ole A.; Hovig, Eivind; Agnarsson, Bjarni A.; Hilmarsson, Rafn; Johannsson, Oskar Th.; Valdimarsson, Trausti; Jonsson, Steinn; Moller, Pall H.; Olafsson, Jon H.; Sigurgeirsson, Bardur; Jonasson, Jon G.; Tryggvason, Geir; Holm, Hilma; Sulem, Patrick; Rafnar, Thorunn; Gudbjartsson, Daniel F.; Stefansson, Kari Share Save
Predicting progression from coronary artery disease to heart failure in community cohorts Pilbrow, A. P.; Tragante, V; Cameron, V. A.; Jones, G. T.; Helgadottir, A.; Troughton, R. W.; Richards, A. M.; Doughty, R. N.; Patel, R. S.; Asselbergs, F. W.; Gudbjartsson, D.; Sulem, P.; Holm, H.; Stefansson, K.; Poppe, K. K. Share Save
Polygenic Interactions With Environmental Exposures in Blood Pressure Regulation: The HUNT Study Ovretveit, Karsten; Ingestrom, Emma M. L.; Spitieris, Michail; Tragante, Vinicius; Thomas, Laurent F.; Steinsland, Ingelin; Brumpton, Ben M.; Gudbjartsson, Daniel F.; Holm, Hilma; Stefansson, Kari; Wisloff, Ulrik; Hveem, Kristian Share Save
Homozygosity for a stop-gain variant in CCDC201 causes primary ovarian insufficiency Oddsson, Asmundur; Steinthorsdottir, Valgerdur; Oskarsson, Gudjon R.; Styrkarsdottir, Unnur; Moore, Kristjan H. S.; Isberg, Salvor; Halldorsson, Gisli H.; Sveinbjornsson, Gardar; Westergaard, David; Nielsen, Henriette Svarre; Fridriksdottir, Run; Jensson, Brynjar O.; Arnadottir, Gudny A.; Jonsson, Hakon; Sturluson, Arni; Snaebjarnarson, Audunn S.; Andreassen, Ole A.; Walters, G. Bragi; Nyegaard, Mette; Erikstrup, Christian; Steingrimsdottir, Thora; Lie, Rolv T.; Melsted, Pall; Jonsdottir, Ingileif; Halldorsson, Bjarni V.; Thorleifsson, Gudmar; Saemundsdottir, Jona; Magnusson, Olafur Th.; Banasik, Karina; Sorensen, Erik; Masson, Gisli; Pedersen, Ole Birger; Tryggvadottir, Laufey; Haavik, Jan; Ostrowski, Sisse Rye; Stefansson, Hreinn; Holm, Hilma; Rafnar, Thorunn; Gudbjartsson, Daniel F.; Sulem, Patrick; Stefansson, Kari Share Save
Loss-of-function variants in ITSN1 confer high risk of Parkinson's disease Skuladottir, Astros Th.; Tragante, Vinicius; Sveinbjornsson, Gardar; Helgason, Hannes; Sturluson, Arni; Bjornsdottir, Anna; Jonsson, Palmi; Palmadottir, Vala; Sveinsson, Olafur A.; Jensson, Brynjar O.; Gudjonsson, Sigurjon A.; Ivarsdottir, Erna V.; Gisladottir, Rosa S.; Gunnarsson, Arni F.; Walters, G. Bragi; Jonsdottir, Gudrun A.; Thorgeirsson, Thorgeir E.; Bjornsdottir, Gyda; Holm, Hilma; Gudbjartsson, Daniel F.; Sulem, Patrick; Stefansson, Hreinn; Stefansson, Kari Share Save
The correlation between CpG methylation and gene expression is driven by sequence variants Stefansson, Olafur Andri; Sigurpalsdottir, Brynja Dogg; Rognvaldsson, Solvi; Halldorsson, Gisli Hreinn; Juliusson, Kristinn; Sveinbjornsson, Gardar; Gunnarsson, Bjarni; Beyter, Doruk; Jonsson, Hakon; Gudjonsson, Sigurjon Axel; Olafsdottir, Thorunn Asta; Saevarsdottir, Saedis; Magnusson, Magnus Karl; Lund, Sigrun Helga; Tragante, Vinicius; Oddsson, Asmundur; Hardarson, Marteinn Thor; Eggertsson, Hannes Petur; Gudmundsson, Reynir L.; Sverrisson, Sverrir; Frigge, Michael L.; Zink, Florian; Holm, Hilma; Stefansson, Hreinn; Rafnar, Thorunn; Jonsdottir, Ingileif; Sulem, Patrick; Helgason, Agnar; Gudbjartsson, Daniel F.; Halldorsson, Bjarni V.; Thorsteinsdottir, Unnur; Stefansson, Kari Share Save
Start codon variant in LAG3 is associated with decreased LAG-3 expression and increased risk of autoimmune thyroid disease Saevarsdottir, Saedis; Bjarnadottir, Kristbjorg; Markusson, Thorsteinn; Berglund, Jonas; Olafsdottir, Thorunn A.; Halldorsson, Gisli H.; Rutsdottir, Gudrun; Gunnarsdottir, Kristbjorg; Arnthorsson, Asgeir Orn; Lund, Sigrun H.; Stefansdottir, Lilja; Gudmundsson, Julius; Johannesson, Ari J.; Sturluson, Arni; Oddsson, Asmundur; Halldorsson, Bjarni; Ludviksson, Bjorn R.; Ferkingstad, Egil; Ivarsdottir, Erna V.; Sveinbjornsson, Gardar; Grondal, Gerdur; Masson, Gisli; Eldjarn, Grimur Hjorleifsson; Thorisson, Gudmundur A.; Kristjansdottir, Katla; Knowlton, Kirk U.; Moore, Kristjan H. S.; Gudjonsson, Sigurjon A.; Rognvaldsson, Solvi; Knight, Stacey; Nadauld, Lincoln D.; Holm, Hilma; Magnusson, Olafur T.; Sulem, Patrick; Gudbjartsson, Daniel F.; Rafnar, Thorunn; Thorleifsson, Gudmar; Melsted, Pall; Norddahl, Gudmundur L.; Jonsdottir, Ingileif; Stefansson, Kari Share Save
Integrative common and rare variant analyses provide insights into the genetic architecture of liver cirrhosis Ghouse, Jonas; Sveinbjornsson, Gardar; Vujkovic, Marijana; Seidelin, Anne-Sofie; Gellert-Kristensen, Helene; Ahlberg, Gustav; Tragante, Vinicius; Rand, Soren A.; Brancale, Joseph; Vilarinho, Silvia; Lundegaard, Pia Rengtved; Sorensen, Erik; Erikstrup, Christian; Bruun, Mie Topholm; Jensen, Bitten Aagaard; Brunak, Soren; Banasik, Karina; Ullum, Henrik; Verweij, Niek; Lotta, Luca; Baras, Aris; Mirshahi, Tooraj; Carey, David J.; Kaplan, David E.; Lynch, Julie; Morgan, Timothy; Schwantes-An, Tae-Hwi; Dochtermann, Daniel R.; Pyarajan, Saiju; Tsao, Philip S.; Laisk, Triin; Magi, Reedik; Kozlitina, Julia; Tybjaerg-Hansen, Anne; Jones, David; Knowlton, Kirk U.; Nadauld, Lincoln; Ferkingstad, Egil; Bjornsson, Einar S.; Ulfarsson, Magnus O.; Sturluson, Arni; Sulem, Patrick; Pedersen, Ole B.; Ostrowski, Sisse R.; Gudbjartsson, Daniel F.; Stefansson, Kari; Olesen, Morten Salling; Chang, Kyong-Mi; Holm, Hilma; Bundgaard, Henning; Stender, Stefan Share Save
Variants at the Interleukin 1 Gene Locus and Pericarditis Thorolfsdottir, Rosa B.; Jonsdottir, Andrea B.; Sveinbjornsson, Gardar; Aegisdottir, Hildur M.; Oddsson, Asmundur; Stefansson, Olafur A.; Halldorsson, Gisli H.; Saevarsdottir, Saedis; Thorleifsson, Gudmar; Stefansdottir, Lilja; Pedersen, Ole B.; Sorensen, Erik; Ghouse, Jonas; Raja, Anna Axelsson; Zheng, Chaoqun; Silajdzija, Elvira; Rand, Soren Albertsen; Erikstrup, Christian; Ullum, Henrik; Mikkelsen, Christina; Banasik, Karina; Brunak, Soren; Ivarsdottir, Erna V.; Sigurdsson, Asgeir; Beyter, Doruk; Sturluson, Arni; Einarsson, Hafsteinn; Tragante, Vinicius; Helgason, Hannes; Lund, Sigrun H.; Halldorsson, Bjarni V.; Sigurpalsdottir, Brynja D.; Olafsson, Isleifur; Arnar, David O.; Thorgeirsson, Gudmundur; Knowlton, Kirk U.; Nadauld, Lincoln D.; Gretarsdottir, Solveig; Helgadottir, Anna; Ostrowski, Sisse R.; Gudbjartssson, Daniel F.; Jonsdottir, Ingileif; Bundgaard, Henning; Holm, Hilma; Sulem, Patrick; Stefansson, Kari Share Save
Variant in the synaptonemal complex protein SYCE2 associates with pregnancy loss through effect on recombination Steinthorsdottir, Valgerdur; Halldorsson, Bjarni V.; Jonsson, Hakon; Palsson, Gunnar; Oddsson, Asmundur; Westergaard, David; Arnadottir, Gudny A.; Stefansdottir, Lilja; Banasik, Karina; Esplin, M. Sean; Hansen, Thomas Folkmann; Brunak, Soren; Nyegaard, Mette; Ostrowski, Sisse Rye; Pedersen, Ole Birger Vesterager; Erikstrup, Christian; Thorleifsson, Gudmar; Nadauld, Lincoln D.; Haraldsson, Asgeir; Steingrimsdottir, Thora; Tryggvadottir, Laufey; Jonsdottir, Ingileif; Gudbjartsson, Daniel F.; Hoffmann, Eva R.; Sulem, Patrick; Holm, Hilma; Nielsen, Henriette Svarre; Stefansson, Kari Share Save
X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements Scholz, Markus; Horn, Katrin; Pott, Janne; Wuttke, Matthias; Kuehnapfel, Andreas; Nasr, M. Kamal; Kirsten, Holger; Li, Yong; Hoppmann, Anselm; Gorski, Mathias; Ghasemi, Sahar; Li, Man; Tin, Adrienne; Chai, Jin-Fang; Cocca, Massimiliano; Wang, Judy; Nutile, Teresa; Akiyama, Masato; Asvold, Bjorn Olav; Bansal, Nisha; Biggs, Mary L.; Boutin, Thibaud; Brenner, Hermann; Brumpton, Ben; Burkhardt, Ralph; Cai, Jianwen; Campbell, Archie; Campbell, Harry; Chalmers, John; Chasman, Daniel, I; Chee, Miao Ling; Li Chee, Miao; Chen, Xu; Cheng, Ching-Yu; Cifkova, Renata; Daviglus, Martha; Delgado, Graciela; Dittrich, Katalin; Edwards, Todd L.; Endlich, Karlhans; Gaziano, J. Michael; Giri, Ayush; Giulianini, Franco; Gordon, Scott D.; Gudbjartsson, Daniel F.; Hallan, Stein; Hamet, Pavel; Hartman, Catharina A.; Hayward, Caroline; Heid, Iris M.; Hellwege, Jacklyn N.; Holleczek, Bernd; Holm, Hilma; Hutri-Kahonen, Nina; Hveem, Kristian; Isermann, Berend; Jonas, Jost B.; Joshi, Peter K.; Kamatani, Yoichiro; Kanai, Masahiro; Kastarinen, Mika; Khor, Chiea Chuen; Kiess, Wieland; Kleber, Marcus E.; Koerner, Antje; Kovacs, Peter; Krajcoviechova, Alena; Kramer, Holly; Kraemer, Bernhard K.; Kuokkanen, Mikko; Kahonen, Mika; Lange, Leslie A.; Lash, James P.; Lehtimaki, Terho; Li, Hengtong; Lin, Bridget M.; Liu, Jianjun; Loeffler, Markus; Lyytikainen, Leo-Pekka; Magnusson, Patrik K. E.; Martin, Nicholas G.; Matsuda, Koichi; Milaneschi, Yuri; Mishra, Pashupati P.; Mononen, Nina; Montgomery, Grant W.; Mook-Kanamori, Dennis O.; Mychaleckyj, Josyf C.; Marz, Winfried; Nauck, Matthias; Nikus, Kjell; Nolte, Ilja M.; Noordam, Raymond; Okada, Yukinori; Olafsson, Isleifur; Oldehinkel, Albertine J.; Penninx, Brenda W. J. H.; Perola, Markus; Pirastu, Nicola; Polasek, Ozren; Porteous, David J.; Poulain, Tanja; Psaty, Bruce M.; Rabelink, Ton J.; Raffield, Laura M.; Raitakari, Olli T.; Rasheed, Humaira; Reilly, Dermot F.; Rice, Kenneth M.; Richmond, Anne; Ridker, Paul M.; Rotter, Jerome, I; Rudan, Igor; Sabanayagam, Charumathi; Salomaa, Veikko; Schneiderman, Neil; Schottker, Ben; Sims, Mario; Snieder, Harold; Stark, Klaus J.; Stefansson, Kari; Stocker, Hannah; Stumvoll, Michael; Sulem, Patrick; Sveinbjornsson, Gardar; Svensson, Per O.; Tai, E-Shyong; Taylor, Kent D.; Tayo, Bamidele O.; Teren, Andrej; Tham, Yih-Chung; Thiery, Joachim; Thio, Chris H. L.; Thomas, Laurent F.; Tremblay, Johanne; Toenjes, Anke; van der Most, Peter J.; Vitart, Veronique; Voelker, Uwe; Wang, Ya Xing; Wang, Chaolong; Wei, Wen Bin; Whitfield, John B.; Wild, Sarah H.; Wilson, James F.; Winkler, Thomas W.; Wong, Tien-Yin; Woodward, Mark; Sim, Xueling; Chu, Audrey Y.; Feitosa, Mary F.; Thorsteinsdottir, Unnur; Hung, Adriana M.; Teumer, Alexander; Franceschini, Nora; Parsa, Afshin; Kottgen, Anna; Schlosser, Pascal; Pattaro, Cristian Share Save
Obesity Variants in the GIPR Gene Are not Associated With Risk of Fracture or Bone Mineral Density Styrkarsdottir, Unnur; Tragante, Vinicius; Stefansdottir, Lilja; Thorleifsson, Gudmar; Oddsson, Asmundur; Sorensen, Erik; Erikstrup, Christian; Schwarz, Peter; Jorgensen, Henrik Lovendahl; Lauritzen, Jes Bruun; Brunak, Soren; Knowlton, Kirk U.; Nadauld, Lincoln D.; Ullum, Henrik; Pedersen, Ole Birger Vesterager; Ostrowski, Sisse Rye; Holm, Hilma; Gudbjartsson, Daniel F.; Sulem, Patrick; Stefansson, Kari Share Save
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