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Sitravatinib in patients with solid tumors selected by molecular alterations: results from a Phase Ib study Bazhenova, Lyudmila; Kim, Dong-Wan; Cho, Byoung Chul; Goel, Sanjay; Heist, Rebecca; Werner, Theresa L.; Eaton, Keith D.; Wang, Judy S.; Pant, Shubham; Adkins, Douglas R.; Blakely, Collin M.; Yan, Xiaohong; Neuteboom, Saskia; Christensen, James G.; Chao, Richard; Bauer, Todd Share Save
Focal adhesion kinase-YAP signaling axis drives drug-tolerant persister cells and residual disease in lung cancer Haderk, Franziska; Chou, Yu-Ting; Cech, Lauren; Fernandez-Mendez, Celia; Yu, Johnny; Olivas, Victor; Meraz, Ismail M.; Rabago, Dora Barbosa; Kerr, D. Lucas; Gomez, Carlos; Allegakoen, David V.; Guan, Juan; Shah, Khyati N.; Herrington, Kari A.; Gbenedio, Oghenekevwe M.; Nanjo, Shigeki; Majidi, Mourad; Tamaki, Whitney; Pourmoghadam, Yashar K.; Rotow, Julia K.; McCoach, Caroline E.; Riess, Jonathan W.; Gutkind, J. Silvio; Tang, Tracy T.; Post, Leonard; Huang, Bo; Santisteban, Pilar; Goodarzi, Hani; Bandyopadhyay, Sourav; Kuo, Calvin J.; Roose, Jeroen P.; Wu, Wei; Blakely, Collin M.; Roth, Jack A.; Bivona, Trever G. Share Save
PERCEPTION predicts patient response and resistance to treatment using single-cell transcriptomics of their tumors Sinha, Sanju; Vegesna, Rahulsimham; Mukherjee, Sumit; Kammula, Ashwin V.; Dhruba, Saugato Rahman; Wu, Wei; Kerr, D. Lucas; Nair, Nishanth Ulhas; Jones, Matthew G.; Yosef, Nir; Stroganov, Oleg V.; Grishagin, Ivan; Aldape, Kenneth D.; Blakely, Collin M.; Jiang, Peng; Thomas, Craig J.; Benes, Cyril H.; Bivona, Trever G.; Schaeffer, Alejandro A.; Ruppin, Eytan Share Save
The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance Caswell, Deborah R.; Gui, Philippe; Mayekar, Manasi K.; Law, Emily K.; Pich, Oriol; Bailey, Chris; Boumelha, Jesse; Kerr, D. Lucas; Blakely, Collin M.; Manabe, Tadashi; Martinez-Ruiz, Carlos; Bakker, Bjorn; Villcas, Juan De Dios Palomino; I. Vokes, Natalie; Dietzen, Michelle; Angelova, Mihaela; Gini, Beatrice; Tamaki, Whitney; Allegakoen, Paul; Wu, Wei; Humpton, Timothy J.; Hill, William; Tomaschko, Mona; Lu, Wei-Ting; Haderk, Franziska; Al Bakir, Maise; Nagano, Ai; Gimeno-Valiente, Francisco; Trecesson, Sophie de Carne; Vendramin, Roberto; Barbe, Vittorio; Mugabo, Miriam; Weeden, Clare E.; Rowan, Andrew; McCoach, Caroline E.; Almeida, Bruna; Green, Mary; Gomez, Carlos; Nanjo, Shigeki; Barbosa, Dora; Moore, Chris; Przewrocka, Joanna; Black, James R. M.; Gronroos, Eva; Suarez-Bonnet, Alejandro; Priestnall, Simon L.; Zverev, Caroline; Lighterness, Scott; Cormack, James; Olivas, Victor; Cech, Lauren; Andrews, Trisha; Rule, Brandon; Jiao, Yuwei; Zhang, Xinzhu; Ashford, Paul; Durfee, Cameron; Venkatesan, Subramanian; Temiz, Nuri Alpay; Tan, Lisa; Larson, Lindsay K.; Argyris, Prokopios P.; Brown, William L.; Yu, Elizabeth A.; Rotow, Julia K.; Guha, Udayan; Roper, Nitin; Yu, Johnny; Vogel, Rachel I.; Thomas, Nicholas J.; Marra, Antonio; Selenica, Pier; Yu, Helena; Bakhoum, Samuel F.; Chew, Su Kit; Reis-Filho, Jorge S.; Jamal-Hanjani, Mariam; Vousden, Karen H.; McGranahan, Nicholas; Van Allen, Eliezer M.; Kanu, Nnennaya; Harris, Reuben S.; Downward, Julian; Bivona, Trever G.; Swanton, Charles Share Save
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Comutations and KRASG12C Inhibitor Efficacy in Advanced NSCLC Negrao, Marcelo V.; Araujo, Haniel A.; Lamberti, Giuseppe; Cooper, Alissa J.; Akhave, Neal S.; Zhou, Teng; Delasos, Lukas; Hicks, J. Kevin; Aldea, Mihaela; Minuti, Gabriele; Hines, Jacobi; Aredo, Jacqueline V.; Dennis, Michael J.; Chakrabarti, Turja; Scott, Susan C.; Bironzo, Paolo; Scheffler, Matthias; Christopoulos, Petros; Stenzinger, Albrecht; Riess, Jonathan W.; Kim, So Yeon; Goldberg, Sarah B.; Li, Mingjia; Wang, Qi; Qing, Yun; Ni, Ying; Do, Minh Truong; Lee, Richard; Ricciuti, Biagio; Alessi, Joao Victor; Wang, Jing; Resuli, Blerina; Landi, Lorenza; Tseng, Shu-Chi; Nishino, Mizuki; Digumarthy, Subba R.; Rinsurongkawong, Waree; Rinsurongkawong, Vadeerat; Vaporciyan, Ara A.; Blumenschein, George R., Jr.; Zhang, Jianjun; Owen, Dwight H.; Blakely, Collin M.; Mountzios, Giannis; Shu, Catherine A.; Bestvina, Christine M.; Garassino, Marina Chiara; Marrone, Kristen A.; Gray, Jhanelle E.; Patel, Sandip Pravin; Cummings, Amy L.; Wakelee, Heather A.; Wolf, Juergen; Scagliotti, Giorgio Vittorio; Cappuzzo, Federico; Barlesi, Fabrice; Patil, Pradnya D.; Drusbosky, Leylah; Gibbons, Don L.; Meric-Bernstam, Funda; Lee, J. Jack; Heymach, John V.; Hong, David S.; Heist, Rebecca S.; Awad, Mark M.; Skoulidis, Ferdinandos Share Save
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Molecular determinants of KRAS p.G12C inhibitor efficacy in advanced NSCLC Negrao, Marcelo V.; Araujo, Haniel A.; Lamberti, Giuseppe; Cooper, Alissa J.; Zhou, Teng; Akhave, Neal; Delasos, Lukas; Hicks, J. Kevin; Aldea, Mihaela; Minuti, Gabriele; Hines, Jacobi; Aredo, Jacqueline V.; Dennis, Michael J.; Chakrabarti, Turja; Scott, Susan; Bironzo, Paolo; Scheffler, Matthias; Christopoulos, Petros; Kim, So Yeon; Goldberg, Sarah; Ni, Ying; Resuli, Blerina; Landi, Lorenza; Tseng, Shu-Chi; Nishino, Mizuki; Owen, Dwight; Blakely, Collin; Mountzios, Giannis; Shu, Catherine A.; Bestvina, Christine; Garassino, Marina; Marrone, Kristen; Gray, Jhanelle; Patel, Sandip Pravin; Cummings, Amy L.; Wakelee, Heather A.; Wolf, Jurgen; Scagliotti, Giorgio V.; Cappuzzo, Federico; Barlesi, Fabrice; Patil, Pradnya; Gibbons, Don L.; Meric-Bernstam, Funda; Lee, J. Jack; Heymach, John V.; Hong, David S.; Heist, Rebecca S.; Awad, Mark M.; Skoulidis, Ferdinandos Share Save
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Control of PKR protein kinase by hepatitis C virus nonstructural 5A protein: Molecular mechanisms of kinase regulation Gale, M; Blakely, CM; Kwieciszewski, B; Tan, SL; Dossett, M; Tang, NM; Korth, MJ; Polyak, SJ; Gretch, DR; Katze, MG Share Save
Osimertinib in NSCLC With Atypical EGFR-Activating Mutations: A Retrospective Multicenter Study Ji, Jingran; Aredo, Jacqueline, V; Piper-Vallillo, Andrew; Huppert, Laura; Rotow, Julia K.; Husain, Hatim; Stewart, Susan; Cobb, Rosemary; Wakelee, Heather A.; Blakely, Collin M.; Wong, Melisa L.; Gubens, Matthew A.; Madani, Mohammad H.; Digumarthy, Subba R.; Mccoach, Caroline; Piotrowska, Zofia; Neal, Joel W.; Riess, Jonathan W. Share Save
Phase 1 Study of Ceritinib Combined With Trametinib in Patients With Advanced ALK- or ROS1-Positive NSCLC Lara, Matthew S.; Gubens, Matthew A.; Bacaltos, Bianca; Daran, Lea; Lim, Steffany L.; Li, Tianhong; Gandara, David R.; Bivona, Trever G.; Riess, Jonathan W.; Blakely, Collin M. Share Save
AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer Noronha, Ashish; Nataraj, Nishanth Belugali; Lee, Joo Sang; Zhitomirsky, Benny; Oren, Yaara; Oster, Sara; Lindzen, Moshit; Mukherjee, Saptaparna; Will, Rainer; Ghosh, Soma; Simoni-Nieves, Arturo; Verma, Aakanksha; Chatterjee, Rishita; Borgoni, Simone; Robinson, Welles; Sinha, Sanju; Brandis, Alexander; Kerr, D. Lucas; Wu, Wei; Sekar, Arunachalam; Giri, Suvendu; Chung, Youngmin; Drago-Garcia, Diana; Danysh, Brian P.; Lauriola, Mattia; Fiorentino, Michelangelo; Ardizzoni, Andrea; Oren, Moshe; Blakely, Collin M.; Ezike, Jideofor; Wiemann, Stefan; Parida, Laxmi; Bivona, Trever G.; Aqeilan, Rami, I; Brugge, Joan S.; Regev, Aviv; Getz, Gad; Ruppin, Eytan; Yarden, Yosef Share Save
Deficiency of the splicing factor RBM10 limits EGFR inhibitor response in EGFR-mutant lung cancer Nanjo, Shigeki; Wu, Wei; Karachaliou, Niki; Blakely, Collin M.; Suzuki, Junji; Chou, Yu-Ting; Ali, Siraj M.; Kerr, D. Lucas; Olivas, Victor R.; Shue, Jonathan; Rotow, Julia; Mayekar, Manasi K.; Haderk, Franziska; Chatterjee, Nilanjana; Urisman, Anatoly; Yeo, Jia Chi; Skanderup, Anders J.; Tan, Aaron C.; Tam, Wai Leong; Arrieta, Oscar; Hosomichi, Kazuyoshi; Nishiyama, Akihiro; Yano, Seiji; Kirichok, Yuriy; Tan, Daniel S. W.; Rosell, Rafael; Okimoto, Ross A.; Bivona, Trever G. Share Save
Entrectinib in NTRK fusion-positive (NTRK-fp) breast cancer: Updated data from STARTRK-2 Lu, J.; Blakely, C. M.; Barve, M.; Chung, C. H.; Waqar, S. N.; Hu, X.; Delord, J-P.; Krzakowski, M. J.; Yonemori, K.; Chen, D. T.; Klingbiel, D.; Heinzmann, S.; Le Tourneau, C. Share Save
Small-molecule targeted therapies induce dependence on DNA double-strand break repair in residual tumor cells Ali, Moiez; Lu, Min; Ang, Hazel Xiaohui; Soderquist, Ryan S.; Eyler, Christine E.; Hutchinson, Haley M.; Glass, Carolyn; Bassil, Christopher F.; Lopez, Omar M.; Kerr, D. Lucas; Falcon, Christina J.; Yu, Helena A.; Hata, Aaron N.; Blakely, Collin M.; McCoach, Caroline E.; Bivona, Trever G.; Wood, Kris C. Share Save
MRTX-500: Phase II trial of sitravatinib (sitra) plus nivolumab (nivo) in patients (pts) with non-squamous (NSQ) non-small cell lung cancer (NSCLC) progressing on or after prior checkpoint inhibitor (CPI) therapy Leal, T. A.; Berz, D.; Rybkin, I.; Iams, W. T.; Bruno, D.; Blakely, C.; Spira, A.; Patel, M.; Waterhouse, D. M.; Richards, D.; Pham, A.; Jotte, R.; Garon, E. B.; Hong, D. S.; Shazer, R.; Yan, X.; Latven, L.; He, K. Share Save
Small Cell Lung Cancer, Version 2.2022 Ganti, Apar Kishor P.; Loo, Billy W.; Bassetti, Michael; Blakely, Collin; Chiang, Anne; D'Amico, Thomas A.; D'Avella, Christopher; Dowlati, Afshin; Downey, Robert J.; Edelman, Martin; Florsheim, Charles; Gold, Kathryn A.; Goldman, Jonathan W.; Grecula, John C.; Hann, Christine; Lams, Wade; Iyengar, Puneeth; Kelly, Karen; Khalil, Maya; Koczywas, Marianna; Merritt, Robert E.; Mohindra, Nisha; Molina, Julian; Moran, Cesar; Pokharel, Saraswati; Puri, Sonam; Qin, Angel; Rusthoven, Chad; Sands, Jacob; Santana-Davila, Rafael; Shafique, Michael; Waqar, Saiama N.; Gregory, Kristina M.; Hughes, Miranda Share Save
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