Not logged in Extensive non-clonal CAR T-cell expansion causing fatal hyperinflammatory syndrome with immune effector cell-associated hemophagocytic lymphohistiocytosis, cytokine release syndrome, and neurotoxicity syndrome Riedel, Andreas; Stanger, Anna M. P.; Kimmich, Lucca M.; Hug, Stefan; Fehn, Adrian E.; Schroeder, Jan C.; Besemer, Britta; Casadei, Nicolas; Demidov, German; Thapa, Prithivi Jung; Faul, Christoph; Hensen, Luca; Lengerke, Claudia; Bethge, Wolfgang Share Save
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SARS-CoV-2 immune responses in patients with multiple myeloma and lenalidomide maintenance therapy Martac, Ioana; Beer, Sina A.; Schenk, Aileen; Ahmad, Osama; Maier, Claus-Philipp; Demirel, Guelay; Preuss, Beate; Klein, Reinhild; Stanger, Anna M. P.; Besemer, Britta; Hensen, Luca; Lengerke, Claudia Share Save
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Long-term safety and immunogenicity of an MF59- adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2 in adults aged 18-55 years or >56 years: 12-month results from a randomised, double-blind, placebo-controlled, phase 1 trial Chappell, Keith J.; Mordant, Francesca L.; Amarilla, Alberto A.; Modhiran, Naphak; Liang, Benjamin; Li, Zheyi; Wijesundara, Danushka K.; Lackenby, Julia A.; Grif, Paul; Bennet, Jillian K.; Hensen, Luca; Zhang, Wuji; Nguyen, Thi H. O.; Tran, Mai H.; Tapley, Peter; Barnes, James; Reading, Patrick C.; Kedzierska, Katherine; Ranasinghe, Charani; Subbarao, Kanta; Watterson, Daniel; Young, Paul R.; Munro, Trent P. Share Save
CD19-Targeting CAR T Cells forMyositis and Interstitial Lung Disease Associated With Antisynthetase Syndrome Pecher, Ann-Christin; Hensen, Luca; Klein, Reinhild; Schairer, Rebekka; Lutz, Katrin; Atar, Daniel; Seitz, Christian; Stanger, Anna; Schneider, Janine; Braun, Christiane; Schmidt, Marina; Horger, Marius; Bornemann, Antje; Faul, Christoph; Bethge, Wolfgang; Henes, Joerg; Lengerke, Claudia Share Save
Immune profiling of SARS-CoV-2 infection during pregnancy reveals NK cell and ?? T cell perturbations Habel, Jennifer R.; Chua, Brendon Y.; Kedzierski, Lukasz; Selva, Kevin J.; Damelang, Timon; Haycroft, Ebene R.; Nguyen, Thi H. O.; Koay, Hui-Fern; Nicholson, Suellen; McQuilten, Hayley A.; Jia, Xiaoxiao; Allen, Lilith F.; Hensen, Luca; Zhang, Wuji; Sandt, Carolien E. van de; Neil, Jessica A.; Pragastis, Katherine; Lau, Jillian S. Y.; Jumarang, Jaycee; Allen, E. Kaitlynn; Amanant, Fatima; Krammer, Florian; Wragg, Kathleen M.; Juno, Jennifer A.; Wheatley, Adam K.; Tan, Hyon-Xhi; Pell, Gabrielle; Walker, Susan; Audsley, Jennifer; Reynaldi, Arnold; Thevarajan, Irani; Denholm, Justin T.; Subbarao, Kanta; Davenport, Miles P.; Hogarth, P. Mark; Godfrey, Dale I.; Cheng, Allen C.; Tong, Steven Y. C.; Bond, Katherine; Williamson, Deborah A.; McMahon, James H.; Thomas, Paul G.; Pannaraj, Pia S.; James, Fiona; Holmes, Natasha E.; Smibert, Olivia C.; Trubiano, Jason A.; Gordon, Claire L.; Chung, Amy W.; Whitehead, Clare L.; Kent, Stephen J.; Lappas, Martha; Rowntree, Louise C.; Kedzierska, Katherine Share Save
Robust SARS-CoV-2 T cell responses with common TCRab motifs toward COVID-19 vaccines in patients with hematological malignancy impacting B cells Nguyen, Thi H. O.; Rowntree, Louise C.; Allen, Lilith F.; Chua, Brendon Y.; Kedzierski, Lukasz; Lim, Chhay; Lasica, Masa; Tennakoon, G. Surekha; Saunders, Natalie R.; Crane, Megan; Chee, Lynette; Seymour, John F.; Anderson, Mary Ann; Whitechurch, Ashley; Clemens, E. Bridie; Zhang, Wuji; Chang, So Young; Habel, Jennifer R.; Jia, Xiaoxiao; McQuilten, Hayley A.; Minervina, Anastasia A.; Pogorelyy, Mikhail V.; Chaurasia, Priyanka; Petersen, Jan; Menon, Tejas; Hensen, Luca; Neil, Jessica A.; Mordant, Francesca L.; Tan, Hyon-Xhi; Cabug, Aira F.; Wheatley, Adam K.; Kent, Stephen J.; Subbarao, Kanta; Karapanagiotidis, Theo; Huang, Han; Vo, Lynn K.; Cain, Natalie L.; Nicholson, Suellen; Krammer, Florian; Gibney, Grace; James, Fiona; Trevillyan, Janine M.; Trubiano, Jason A.; Mitchell, Jeni; Christensen, Britt; Bond, Katherine A.; Williamson, Deborah A.; Rossjohn, Jamie; Crawford, Jeremy Chase; Thomas, Paul G.; Thursky, Karin A.; Slavin, Monica A.; Tam, Constantine S.; Teh, Benjamin W.; Kedzierska, Katherine Share Save
SARS-CoV-2 infection results in immune responses in the respiratory tract and peripheral blood that suggest mechanisms of disease severity Zhang, Wuji; Chua, Brendon Y.; Selva, Kevin J.; Kedzierski, Lukasz; Ashhurst, Thomas M.; Haycroft, Ebene R.; Shoffner-Beck, Suzanne K.; Hensen, Luca; Boyd, David F.; James, Fiona; Mouhtouris, Effie; Kwong, Jason C.; Chua, Kyra Y. L.; Drewett, George; Copaescu, Ana; Dobson, Julie E.; Rowntree, Louise C.; Habel, Jennifer R.; Allen, Lilith F.; Koay, Hui-Fern; Neil, Jessica A.; Gartner, Matthew J.; Lee, Christina Y.; Andersson, Patiyan; Khan, Sadid F.; Blakeway, Luke; Wisniewski, Jessica; McMahon, James H.; Vine, Erica E.; Cunningham, Anthony L.; Audsley, Jennifer; Thevarajan, Irani; Seemann, Torsten; Sherry, Norelle L.; Amanat, Fatima; Krammer, Florian; Londrigan, Sarah L.; Wakim, Linda M.; King, Nicholas J. C.; Godfrey, Dale I.; Mackay, Laura K.; Thomas, Paul G.; Nicholson, Suellen; Arnold, Kelly B.; Chung, Amy W.; Holmes, Natasha E.; Smibert, Olivia C.; Trubiano, Jason A.; Gordon, Claire L.; Nguyen, Thi H. O.; Kedzierska, Katherine Share Save
T Cell Epitope Discovery in the Context of Distinct and Unique Indigenous HLA Profiles Hensen, Luca; Illing, Patricia T.; Rowntree, Louise C.; Davies, Jane; Miller, Adrian; Tong, Steven Y. C.; Habel, Jennifer R.; van de Sandt, Carolien E.; Flanagan, Katie L.; Purcell, Anthony W.; Kedzierska, Katherine; Clemens, E. Bridie Share Save
Integrated immune networks in SARS-CoV-2 infected pregnant women reveal differential NK cell and unconventional T cell activation Habel, Jennifer R.; Chua, Brendon Y.; Kedzierski, Lukasz; Selva, Kevin J.; Damelang, Timon; Haycroft, Ebene R.; Nguyen, Thi H. O.; Koay, Hui-Fern; Nicholson, Suellen; McQuilten, Hayley; Jia, Xiaoxiao; Allen, Lilith F.; Hensen, Luca; Zhang, Wuji; van de Sandt, Carolien E.; Neil, Jessica A.; Amanant, Fatima; Krammer, Florian; Wragg, Kathleen; Juno, Jennifer A.; Wheatley, Adam K.; Tan, Hyon-Xhi; Pell, Gabrielle; Audsley, Jennifer; Reynaldi, Arnold; Thevarajan, Irani; Denholm, Justin; Subbarao, Kanta; Davenport, Miles P.; Hogarth, Mark; Godrey, Dale I.; Cheng, Allen C.; Tong, Steven Yc; Bond, Katherine; Williamson, Deborah A.; James, Fiona; Holmes, Natasha E.; Smibert, Olivia C.; Trubiano, Jason A.; Gordon, Claire L.; Chung, Amy W.; Whitehead, Claire; Kent, Stephen J.; Lappas, Martha; Rowntree, Louise C. Share Save
HLA-A*11:01-restricted CD8+ T cell immunity against influenza A and influenza B viruses in Indigenous and non-Indigenous people Habel, Jennifer; Nguyen, Andrea; Rowntree, Louise; Szeto, Christopher; Mifsud, Nicole; Clemens, E. Bridie; Loh, Liyen; Chen, Weisan; Rockman, Steve; Nelson, Jane W.; Davies, Jane; Miller, Adrian; Tong, Steven Y. C. T.; Rossjohn, Jamie; Gras, Stephanie M.; Purcell, Anthony; Hensen, Luca M.; Kedzierska, Katherine; Illing, Patricia M. Share Save
Influenza virus infection history shapes antibody responses to influenza vaccination Auladell, Maria; Hoang Vu Mai Phuong; Le Thi Quynh Mai; Tseng, Yeu-Yang; Carolan, Louise; Wilks, Sam; Pham Quang Thai; Price, David; Nguyen Thanh Duong; Nguyen Le Khang Hang; Le Thi Thanh; Nguyen Thi Hong Thuong; Tran Thi Kieu Huong; Nguyen Thi Ngoc Diep; Vu Thi Ngoc Bich; Khvorov, Arseniy; Hensen, Luca; Tran Nhu Duong; Kedzierska, Katherine; Dang Duc Anh; Wertheim, Heiman; Boyd, Scott D.; Good-Jacobson, Kim L.; Smith, Derek; Barr, Ian; Sullivan, Sheena; van Doorn, H. Rogier; Fox, Annette Share Save
Robust and prototypical immune responses toward influenza vaccines in the high-risk group of Indigenous Australians Hensen, Luca; Nguyen, Thi H. O.; Rowntree, Louise C.; Damelang, Timon; Koutsakos, Marios; Aban, Malet; Hurt, Aeron; Harland, Kim L.; Auladell, Maria; van de Sandt, Carolien E.; Everitt, Anngie; Blacker, Cath; Oyong, Damian A.; Loughland, Jessica R.; Webb, Jessica R.; Wines, Bruce D.; Hogarth, P. Mark; Flanagan, Katie L.; Plebanski, Magdalena; Wheatley, Adam; Chung, Amy W.; Kent, Stephen J.; Miller, Adrian; Clemens, E. Bridie; Doherty, Peter C.; Nelson, Jane; Davies, Jane; Tong, Steven Y. C.; Kedzierska, Katherine Share Save
Safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2: a randomised, double-blind, placebo-controlled, phase 1 trial Chappell, Keith J.; Mordant, Francesca L.; Li, Zheyi; Wijesundara, Danushka K.; Ellenberg, Paula; Lackenby, Julia A.; Cheung, Stacey T. M.; Modhiran, Naphak; Avumegah, Michael S.; Henderson, Christina L.; Hoger, Kym; Griffin, Paul; Bennet, Jillian; Hensen, Luca; Zhang, Wuji; Nguyen, Thi H. O.; Marrero-Hernandez, Sara; Selva, Kevin J.; Chung, Amy W.; Tran, Mai H.; Tapley, Peter; Barnes, James; Reading, Patrick C.; Nicholson, Suellen; Corby, Stavroula; Holgate, Thomas; Wines, Bruce D.; Hogarth, P. Mark; Kedzierska, Katherine; Purcell, Damian F. J.; Ranasinghe, Charani; Subbarao, Kanta; Watterson, Daniel; Young, Paul R.; Munro, Trent P. Share Save
Altered microRNA expression in COVID-19 patients enables identification of SARS-CoV-2 infection Farr, Ryan J.; Rootes, Christina L.; Rowntree, Louise C.; Nguyen, Thi H. O.; Hensen, Luca; Kedzierski, Lukasz; Cheng, Allen C.; Kedzierska, Katherine; Au, Gough G.; Marsh, Glenn A.; Vasan, Seshadri S.; Foo, Chwan Hong; Cowled, Christopher; Stewart, Cameron R. Share Save
SARS-CoV-2-specific CD8+ T-cell responses and TCR signatures in the context of a prominent HLA-A*24:02 allomorph Rowntree, Louise C.; Petersen, Jan; Juno, Jennifer A.; Chaurasia, Priyanka; Wragg, Kathleen; Koutsakos, Marios; Hensen, Luca; Wheatley, Adam K.; Kent, Stephen J.; Rossjohn, Jamie; Kedzierska, Katherine; Nguyen, Thi H. O. Share Save
CD8+ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph Hensen, Luca; Illing, Patricia T.; Bridie Clemens, E.; Nguyen, Thi H. O.; Koutsakos, Marios; van de Sandt, Carolien E.; Mifsud, Nicole A.; Nguyen, Andrea T.; Szeto, Christopher; Chua, Brendon Y.; Halim, Hanim; Rizzetto, Simone; Luciani, Fabio; Loh, Liyen; Grant, Emma J.; Saunders, Phillipa M.; Brooks, Andrew G.; Rockman, Steve; Kotsimbos, Tom C.; Cheng, Allen C.; Richards, Michael; Westall, Glen P.; Wakim, Linda M.; Loudovaris, Thomas; Mannering, Stuart I.; Elliott, Michael; Tangye, Stuart G.; Jackson, David C.; Flanagan, Katie L.; Rossjohn, Jamie; Gras, Stephanie; Davies, Jane; Miller, Adrian; Tong, Steven Y. C.; Purcell, Anthony W.; Kedzierska, Katherine Share Save
Immune cellular networks underlying recovery from influenza virus infection in acute hospitalized patients Nguyen, Thi H. O.; Koutsakos, Marios; van de Sandt, Carolien E.; Crawford, Jeremy Chase; Loh, Liyen; Sant, Sneha; Grzelak, Ludivine; Allen, Emma K.; Brahm, Tim; Clemens, E. Bridie; Auladell, Maria; Hensen, Luca; Wang, Zhongfang; Nussing, Simone; Jia, Xiaoxiao; Gunther, Patrick; Wheatley, Adam K.; Kent, Stephen J.; Aban, Malet; Deng, Yi-Mo; Laurie, Karen L.; Hurt, Aeron C.; Gras, Stephanie; Rossjohn, Jamie; Crowe, Jane; Xu, Jianqing; Jackson, David; Brown, Lorena E.; La Gruta, Nicole; Chen, Weisan; Doherty, Peter C.; Turner, Stephen J.; Kotsimbos, Tom C.; Thomas, Paul G.; Cheng, Allen C.; Kedzierska, Katherine Share Save
CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope display high naive precursor frequency and TCR promiscuity Nguyen, Thi H. O.; Rowntree, Louise C.; Petersen, Jan; Chua, Brendon Y.; Hensen, Luca; Kedzierski, Lukasz; van de Sandt, Carolien E.; Chaurasia, Priyanka; Tan, Hyon-Xhi; Habel, Jennifer R.; Zhang, Wuji; Allen, Lilith F.; Earnest, Linda; Mak, Kai Yan; Juno, Jennifer A.; Wragg, Kathleen; Mordant, Francesca L.; Amanat, Fatima; Krammer, Florian; Mifsud, Nicole A.; Doolan, Denise L.; Flanagan, Katie L.; Sonda, Sabrina; Kaur, Jasveen; Wakim, Linda M.; Westall, Glen P.; James, Fiona; Mouhtouris, Effie; Gordon, Claire L.; Holmes, Natasha E.; Smibert, Olivia C.; Trubiano, Jason A.; Cheng, Allen C.; Harcourt, Peter; Clifton, Patrick; Crawford, Jeremy Chase; Thomas, Paul G.; Wheatley, Adam K.; Kent, Stephen J.; Rossjohn, Jamie; Torresi, Joseph; Kedzierska, Katherine Share Save
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