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E

Edward Gane

university of auckland

97H-index
726Paper Count
5.7WCitation Count
Published Papers 361
Publication Date
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Letter: Reconsidering Tenofovir Disoproxil Fumarate Use in Light of Emerging Safety Evidence—Authors' Reply
errALIMENTARY PHARMACOLOGY & THERAPEUTICS
IF6.7
err2026-06-10
err0
errOAAI
errGrace L. H. Wong; Edward Gane; Wan-Long Chuang; Maria Buti; the Study Team
errShare
errSave
Safety, Tolerability, and Pharmacodynamics of GS-4224 in Healthy Participants and Participants With Chronic Hepatitis B
errLiver International
IF5.2
err2026-05-21
err0
PREAI
errEdward J. Gane; Chi-Yi Chen; Cheng-Hao Tseng; Chun-Yen Lin; Stuart K. Roberts; Dana Tedesco; Frida Abramov; Fangqiu Zhang; Jared M. Odegard; Jeffrey J. Wallin; Naveed A. Shaik; Teri Chew; Latesh Lad; Adele Y. Wang; Scott Balsitis; Simon P. Fletcher; Audrey H. Lau; Wan-Long Chuang; Kosh Agarwal
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errSave
A plain language summary of the CheckMate 9DW study: nivolumab in combination with ipilimumab for unresectable hepatocellular carcinoma (advanced liver cancer)
errFuture Oncology
IF2.6
err2026-04-14
err0
PREAI
errThomas Yau; Peter R Galle; Thomas Decaens; Bruno Sangro; Shukui Qin; Leonardo G da Fonseca; Hatim Karachiwala; Jean-Frederic Blanc; Joong-Won Park; Edward Gane; Matthias Pinter; Ana Matilla Peña; Masafumi Ikeda; David Tai; Armando Santoro; Gonzalo Pizarro; Chang-Fang Chiu; Michael Schenker; Aiwu He; Hong Jae Chon; Joanna Wojcik-Tomaszewska; Gontran Verset; Qi Qi Wang; Caitlyn Stromko; Jaclyn Neely; Prianka Singh; Maria Jesus Jimenez Exposito; Masatoshi Kudo
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errSave
An oral, liver-restricted LXR inverse agonist for dyslipidemia: preclinical development and phase 1 trial
errNature Medicine
IF50
err2026-01-16
err0
errOAAI
errXiaoxu Li; Giorgia Benegiamo; Archana Vijayakumar; Natalie Sroda; Masaki Kimura; Ryan S. Huss; Steve Weng; Eisuke Murakami; Brian J. Kirby; Giacomo V. G. von Alvensleben; Claus Kremoser; Edward J. Gane; Takanori Takebe; Robert P. Myers; G. Mani Subramanian; Johan Auwerx
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errSave
Corrigendum to “Peginterferon-alpha-2a add-on to treatment with siRNA JNJ-73763989 in virologically suppressed chronic hepatitis B: The phase II PENGUIN study” [JHEP Reports 2025 7(10) 101516]
errJHEP Reports
IF7.5
err2025-11-24
err0
errOAAI
errEdward Gane; Ewa Janczewska; Tetsuo Takehara; Wan-Long Chuang; Cheng-Yuan Peng; Maria Hlebowicz; Yasuhiro Asahina; Ting-Tsung Chang; Ronald Kalmeijer; John Jezorwski; Gloria Kim; Zacharias Anastasiou; Thomas N. Kakuda; Thierry Verbinnen; Nonko Pehlivanov; Adam Bakala; Oliver Lenz; Michael Biermer
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errSave
A Phase 2 Trial of Tobevibart plus Elebsiran in Hepatitis D
errNEW ENGLAND JOURNAL OF MEDICINE
IF78.5
err2025-11-01
err2
PREAI
errAsselah, Tarik; Chattergoon, Michael A.; Jucov, Alina; Streinu-Cercel, Anca; Lampertico, Pietro; Wedemeyer, Heiner; Kennedy, Patrick T.; Gane, Edward J.; Bullard, Brianna L.; Chow, Sophia; Santos, Desiree; Camus, Gregory; Lu, Yimeng; Pilowa, Cara; Hwang, Carey; Correll, Todd; Agarwal, Kosh
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errSave
Letters on “Efficacy and Safety of Tenofovir Alafenamide (TAF) and Tenofovir Disoproxil Fumarate (TDF) Followed by TAF in Chronic Hepatitis B Patients of East Asian Ethnicity Following 5 Years of Treatment.” Authors' Reply
errAlimentary Pharmacology & Therapeutics
IF6.7
err2025-10-11
err0
errOAAI
errGrace Lai-Hung Wong; Edward J. Gane; Wan-Long Chuang; María Buti
errShare
errSave
Safety and efficacy of tenofovir alafenamide in preventing hepatitis B virus recurrence after liver transplantation in patients with chronic kidney disease maintained on tenofovir disoproxil fumarate: results from a phase 2 randomized trial
errAmerican Journal of Transplantation
IF8.2
err2025-09-17
err0
PREAI
errEdward J. Gane; Rica Dagooc; Dominic Ray-Chaudhuri; Vithika Suri; Frida Abramov; Curtis D. Holt; Hongyuan Wang; Catherine Frenette; Anu O. Osinusi; John F. Flaherty
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errSave
Efficacy and Safety of Tenofovir Alafenamide (TAF) and Tenofovir Disoproxil Fumarate (TDF) Followed by TAF in Chronic Hepatitis B Patients of East Asian Ethnicity Following 5 Years of Treatment
errAlimentary Pharmacology & Therapeutics
IF6.7
err2025-08-12
err0
errOAAI
errGrace Lai-Hung Wong; Edward Gane; Calvin Q. Pan; Scott Fung; Mang M. Ma; Namiki Izumi; Shalimar; Seng Gee Lim; Wan-Long Chuang; Rajiv Mehta; Young-Suk Lim; Leland J. Yee; John F. Flaherty; Frida Abramov; Hongyuan Wang; Maria Buti
errShare
errSave
Peginterferon-alpha-2a add-on to treatment with siRNA JNJ-73763989 in virologically suppressed chronic hepatitis B: the phase 2 PENGUIN study
errJHEP Reports
IF7.5
err2025-07-09
err0
errOAAI
errEdward Gane; Ewa Janczewska; Tetsuo Takehara; Wan-Long Chuang; Cheng-Yuan Peng; Maria Hlebowicz; Yasuhiro Asahina; Ting-Tsung Chang; Ronald Kalmeijer; John Jezorwski; Gloria Kim; Zacharias Anastasiou; Thomas N. Kakuda; Thierry Verbinnen; Nonko Pehlivanov; Adam Bakala; Oliver Lenz; Michael Biermer
errShare
errSave
VIR-2218 (elebsiran) plus pegylated interferon-alfa-2a in participants with chronic hepatitis B virus infection: a phase 2 study
errLANCET GASTROENTEROLOGY & HEPATOLOGY
IF38.6
err2024-12-01
err3
PREAI
errYuen, Man-Fung; Lim, Young-Suk; Yoon, Ki Tae; Lim, Tien-Huey; Heo, Jeong; Tangkijvanich, Pisit; Tak, Won Young; Thanawala, Vaidehi; Cloutier, Daniel; Mao, Shenghua; Arizpe, Andre; Cathcart, Andrea L.; Gupta, Sneha, V; Hwang, Carey; Gane, Edward
errShare
errSave
Efficacy, tolerability and pharmacokinetics of survodutide, aglucagon/glucagon-like peptide-1 receptor dual agonist,in cirrhosis
errJOURNAL OF HEPATOLOGY
IF33
err2024-11-01
err6
errOAAI
errLawitz, Eric J.; Fraessdorf, Mandy; Neff, Guy W.; Schattenberg, Joern M.; Noureddin, Mazen; Alkhouri, Naim; Schmid, Bernhard; Andrews, Charles P.; Takacs, Istvan; Hussain, Samina Ajaz; Fenske, Wiebke K.; Gane, Edward J.; Hosseini-Tabatabaei, Azadeh; Sanyal, Arun J.; Mazo, Daniel F.; Younes, Ramy
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errSave
Eight-year efficacy and safety of tenofovir alafenamide for treatment of chronic hepatitis B virus infection: Final results from two randomised phase 3 trials
errALIMENTARY PHARMACOLOGY & THERAPEUTICS
IF6.7
err2024-09-27
err2
errOAAI
errButi, Maria; Lim, Young-Suk; Chan, Henry Lik Yuen; Agarwal, Kosh; Marcellin, Patrick; Brunetto, Maurizia R.; Chuang, Wan-Long; Janssen, Harry L. A.; Fung, Scott K.; Izumi, Namiki; Jablkowski, Maciej S.; Abdurakhmanov, Dzhamal; Abramov, Frida; Wang, Hongyuan; Botros, Irina; Yee, Leland J.; Mateo, Roberto; Flaherty, John F.; Osinusi, Anu; Pan, Calvin Q.; Shalimar, X.; Seto, Wai-Kay; Gane, Edward J.
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errSave
Safety, PK, and Preliminary Efficacy of the Liver-Targeted Mitochondrial Protonophore TLC-6740-A Phase 1 Study
errDIABETES
IF7.5
err2024-06-14
err0
PREAI
errGane, Edward; Huss, Ryan S.; Sur, Jane; Murakami, Eisuke; Weng, Steve; Kirby, Brian J.; Shah, Amrik; Shulman, Gerald I.; Subramanian, Mani; Vijayakumar, Archana; Myers, Robert P.
errShare
errSave
Personalized neoantigen vaccine and pembrolizumab in advanced hepatocellular carcinoma: a phase 1/2 trial
errNATURE MEDICINE
IF50
err2024-04-07
err18
errOAAI
errYarchoan, Mark; Gane, Edward J.; Marron, Thomas U.; Perales-Linares, Renzo; Yan, Jian; Cooch, Neil; Shu, Daniel H.; Fertig, Elana J.; Kagohara, Luciane T.; Bartha, Gabor; Northcott, Josette; Lyle, John; Rochestie, Sarah; Peters, Joann; Connor, Jason T.; Jaffee, Elizabeth M.; Csiki, Ildiko; Weiner, David B.; Perales-Puchalt, Alfredo; Sardesai, Niranjan Y.
errShare
errSave
Cabozantinib plus atezolizumab versus sorafenib for advanced hepatocellular carcinoma (COSMIC-312): final results of a randomised phase 3 study
errLANCET GASTROENTEROLOGY & HEPATOLOGY
IF38.6
err2024-04-01
err19
PREAI
errYau, Thomas; Kaseb, Ahmed; Cheng, Ann-Lii; Qin, Shukui; Zhu, Andrew X.; Chan, Stephen L.; Melkadze, Tamar; Sukeepaisarnjaroen, Wattana; Breder, Valery; Verset, Gontran; Gane, Edward; Borbath, Ivan; Rangel, Jose David Gomez; Ryoo, Baek-Yeol; Makharadze, Tamta; Merle, Philippe; Benzaghou, Fawzi; Milwee, Steven; Wang, Zhong; Curran, Dominic; Kelley, Robin Kate; Rimassa, Lorenza
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errSave
Long-term open-label vebicorvir for chronic HBV infection: Safety and off-treatment responses
errJHEP REPORTS
IF7.5
err2024-04-01
err1
errOAAI
errYuen, Man-Fung; Fung, Scott; Ma, Xiaoli; Nguyen, Tuan T.; Hassanein, Tarek; Hann, Hie -Won; Elkhashab, Magdy; Nahass, Ronald G.; Park, James S.; Jacobson, Ira M.; Ayoub, Walid S.; Han, Steven -Huy; Gane, Edward J.; Zomorodi, Katie; Yan, Ran; Ma, Julie; Knox, Steven J.; Stamm, Luisa M.; Bonacini, Maurizio; Weilert, Frank; Ramji, Alnoor; Bennett, Michael; Ravendhran, Natarajan; Chan, Sing; Dieterich, Douglas T.; Kwo, Paul Yien; Schiff, Eugene R.; Bae, Ho S.; Lalezari, Jacob; Agarwal, Kosh; Sulkowski, Mark S.
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errSave
Efficacy, safety, and pharmacokinetics of capsid assembly modulator linvencorvir plus standard of care in chronic hepatitis B patients
errCLINICAL AND MOLECULAR HEPATOLOGY
IF16.9
err2024-04-01
err2
errOAAI
errHou, Jinlin; Gane, Edward; Balabanska, Rozalina; Zhang, Wenhong; Zhang, Jiming; Lim, Tien Huey; Xie, Qing; Yeh, Chau-Ting; Yang, Sheng-Shun; Liang, Xieer; Komolmit, Piyawat; Leerapun, Apinya; Xue, Zenghui; Chen, Ethan; Zhang, Yuchen; Xie, Qiaoqiao; Chang, Ting-Tsung; Hu, Tsung-Hui; Lim, Seng Gee; Chuang, Wan -Long; Leggett, Barbara; Bo, Qingyan; Zhou, Xue; Triyatni, Miriam; Zhang, Wen; Yuen, Man-Fung
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errSave
Personalized neoantigen DNA vaccine GNOS-PV02 and pembrolizumab as second-line treatment for advanced hepatocellular carcinoma
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errYarchoan, Mark; Gane, Edward J.; Marron, Thomas U.; Perales-Linares, Renzo; Yan, Jian; Cooch, Neil; Shu, Daniel; Fertig, Elana J.; Kagohara, Luciane T.; Bartha, Gabor; Northcott, Josette; Lyle, John; Rochestie, Sarah; Peters, Joann; Connor, Jason; Jaffee, Elizabeth; Perales-Puchalt, Alfredo; Weiner, David B.; Csiki, Ildiko; Sardesai, Niranjan Y.
errShare
errSave
Detection of circulating tumor DNA predicts survival in advanced HCC patients treated with personalized therapeutic DNA cancer vaccine in combination with immune checkpoint blockade
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errYan, Jian; Li, Bailiang; Northcott, Josette; Abbott, Charles W.; Pyke, Rachel M.; Perales-Linares, Renzo; Cooch, Neil; Rochestie, Sarah; Peters, Joann; Gane, Edward J.; Yarchoan, Mark; Marron, Thomas U.; Boyle, Sean M.; Csiki, Ildiko; Chen, Richard; Sardesai, Niranjan Y.
errShare
errSave

Research Directions

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