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Exploiting the therapeutic vulnerability of IDH-mutant gliomas with zotiraciclib Pang, Ying; Li, Qi; Sergi, Zach; Yu, Guangyang; Kim, Olga; Lu, Peng; Chan, Marina; Sang, Xueyu; Wang, Herui; Ranjan, Alice; Robey, Robert W.; Soheilian, Ferri; Tran, Bao; Nunez, Felipe J.; Zhang, Meili; Song, Hua; Zhang, Wei; Davis, Dionne; Gilbert, Mark R.; Gottesman, Michael M.; Liu, Zhenggang; Thomas, Craig J.; Castro, Maria G.; Gujral, Taranjit S.; Wu, Jing Share Save
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PEDIATRIC GLIOMA IMMUNE PROFILING IDENTIFIES TIM3 AS A THERAPEUTIC TARGET IN BRAF-FUSION PILOCYTIC ASTROCYTOMA Tripathi, Shashwat; Najem, Hinda; Dussold, Corey; Pacheco, Sebastian; Du, Ruochen; Sooreshjani, Moloud; Chandler, James; Stupp, Roger; Sonabend, Adam; Horbinski, Craig; Lukas, Rimas; Xiu, Joanne; Nicolaides, Theodore; Brown, Valerie; Wadhwani, Nitin; Lam, Sandi; James, Charles; Rao, Ganesh; Castro, Maria; Heimberger, Amy; Decuypere, Michael Share Save
IDH1-R132H REWIRES AUTOPHAGY IN THE GLIOMA MICROENVIRONMENT TO FACILITATE TUMOR PROGRESSION AND RESPONSE TO RADIATION Banerjee, Kaushik; Nunez, Felipe; Mujeeb, Anzar; Mausar, Ava; Tronrud, Claire; Zhu, Ziwen; Taher, Ayman; Kadiyala, Padma; Carney, Stephen; Garcia-Fabiani, Maria Belen; Comba, Andrea; Alghamri, Mahmoud; Mcclellan, Brandon; Faisal, Syed; Nwosu, Zeribe; Hong, Hanna; Qin, Tingting; Sartor, Maureen; Ljungman, Mats; Cheng, Shi-Yuan; Appleman, Henry; Lowenstein, Pedro; Lahann, Joerg; Lyssiotis, Costas; Castro, Maria Share Save
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TUMOR ASSOCIATED MACROPHAGES DRIVE TUMOR PROGRESSION AND ARE TRANSCRIPTIONALLY SHAPED BY HISTONE MUTATIONS IN DIFFUSE MIDLINE GLIOMA Ross, James; Puigdelloses-Vallcorba, Montserrat; Pinero, Gonzalo; Soni, Nishant; Thomason, Wes; Desisto, John; Angione, Angelo; Tsankova, Nadejda; Castro, Maria; Schniederjan, Matthew; Wadhwani, Nitin; Raju, G. Praveen; Morgenstern, Peter; Becher, Oren; Green, Adam; Tsankov, Alexander; Hambardzumyan, Dolores Share Save
IMPACT OF ZOTIRACICLIB ON GLIOMA TUMOR MICROENVIRONMENT Lu, Peng; Li, Qi; Kim, Olga; Sergi, Zach; Gilbert, Mark; Zhang, Meili; Zhang, Wei; Song, Hua; Briceno, Nicole; Davis, Dionne; Wong, Zalman; Castro, Maria G.; Wu, Jing Share Save
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THE IMPACT OF THE IDH1 R132H MUTATION ON MMP2 METHYLATION, EXPRESSION AND INVASION IN EXPERIMENTAL GLIOMAS AND HUMAN GBMS Lenkiewicz, A. M.; Ibragimova, A.; Ghosh, M.; Szadkowska, P.; Ellert-Miklaszewska, A.; Baluszek, S.; Jacek, K.; Castro, M.; Kaminska, B. Share Save
Pediatric glioma immune profiling identifies TIM3 as a therapeutic target in BRAF fusion pilocytic astrocytoma Tripathi, Shashwat; Najem, Hinda; Dussold, Corey; Pacheco, Sebastian; Du, Ruochen; Sooreshjani, Moloud; Hurley, Lisa; Chandler, James P.; Stupp, Roger; Sonabend, Adam M.; Horbinski, Craig M.; Lukas, Rimas V.; Xiu, Joanne; Lopez, Giselle; Nicolaides, Theodore P.; Brown, Valerie; Wadhwani, Nitin R.; Lam, Sandi K.; James, Charles David; Rao, Ganesh; Castro, Maria G.; Heimberger, Amy B.; Decuypere, Michael Share Save
Purine salvage promotes treatment resistance in H3K27M-mutant diffuse midline glioma Peterson, Erik R.; Sajjakulnukit, Peter; Scott, Andrew J.; Heaslip, Caleb; Andren, Anthony; Wilder-Romans, Kari; Zhou, Weihua; Palavalasa, Sravya; Korimerla, Navyateja; Lin, Angelica; O'Brien, Alexandra; Kothari, Ayesha; Zhao, Zitong; Zhang, Li; Morgan, Meredith A.; Venneti, Sriram; Koschmann, Carl; Jabado, Nada; Lyssiotis, Costas A.; Castro, Maria G.; Wahl, Daniel R. Share Save
Adaptive purine metabolism drives radiation therapy resistance in H3K27M-diffuse midline glioma Peterson, Erik R.; Sajjakulnukit, Peter; Scott, Andrew; Heaslip, Caleb; Andren, Anthony; Wilder-Romans, Kari; Lin, Angelica; Obrien, Alexandra; Zhao, Zitong; Zhang, Li; Venneti, Sriram; Koschmann, Carl; Jabado, Nada; Castro, Maria G.; Wahl, Daniel R. Share Save
Spatiotemporal Insights into Glioma Oncostream Dynamics: Unraveling Formation, Stability, and Disassembly Pathways Faisal, Syed M.; Clewner, Jarred E.; Stack, Brooklyn; Varela, Maria L.; Comba, Andrea; Abbud, Grace; Motsch, Sebastien; Castro, Maria G.; Lowenstein, Pedro R. Share Save
Interplay between ATRX and IDH1 mutations governs innate immune responses in diffuse gliomas Hariharan, Seethalakshmi; Whitfield, Benjamin T.; Pirozzi, Christopher J.; Waitkus, Matthew S.; Brown, Michael C.; Bowie, Michelle L.; Irvin, David M.; Roso, Kristen; Fuller, Rebecca; Hostettler, Janell; Dharmaiah, Sharvari; Gibson, Emiley A.; Briley, Aaron; Mangoli, Avani; Fraley, Casey; Shobande, Mariah; Stevenson, Kevin; Zhang, Gao; Malgulwar, Prit Benny; Roberts, Hannah; Roskoski, Martin; Spasojevic, Ivan; Keir, Stephen T.; He, Yiping; Castro, Maria G.; Huse, Jason T.; Ashley, David M. Share Save
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