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张

张先正 (Xian‐Zheng Zhang)

wuhan university

124H-index
848Paper Count
5.5WCitation Count
Published Papers 624
Publication Date
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Inhalable ROS-responsive liposomes for orchestrating microenvironment remodeling and epithelial regeneration in pulmonary fibrosis
errScience China-Materials
IF7.4
err2026-08-19
err0
PREAI
errJia-Min Xie; Rui-Qi Zhao; Xin-Chen Deng; Wei-Qin Yao; Jia-Hao Liu; Wei-Hai Chen; Xian-Zheng Zhang
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errSave
Corrigendum to ‘Engineered Bdellovibrio bacteriovorus enhances antibiotic penetration and biofilm eradication’ [Journal of Controlled Release 380 (2025) 283–296]
errJournal of Controlled Release
IF11.5
err2026-08-06
err0
PREAI
errYing Tang; Yang Chen; Yong-Dan Qi; Hui-Yi Yan; Wen-An Peng; Yu-Qiang Wang; Qian-Xiao Huang; Xin-Hua Liu; Jing-Jie Ye; Yun Yu; Xian-Zheng Zhang; Cui Huang
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errSave
Reprogramming glutamine-polyamine axis via engineered probiotic-nanoreactor biohybrids for metabolic-radio-immunotherapy of pancreatic cancer
errMaterials Today
IF22
err2026-06-19
err0
PREAI
errWei-Qin Yao; Xin-Chen Deng; Xu-Qi Hu; Hong Chen; Jun Feng; Wei-Hai Chen; Xian-Zheng Zhang
errShare
errSave
Engineered Bacterial Protoplasts for Spatiotemporally Controlled Tumor Immunotherapy
errAdvanced Functional Materials
IF19
err2026-06-12
err0
PREAI
errYun Zhang; Qian-Ru Li; Zhu Chen; Xiao Yan; Jin-Lian He; Bao-Ting Dong; Xin-Chen Deng; Jian-Hua Yan; Si-Xue Cheng; Xian-Zheng Zhang
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errSave
Multifunctional Immunomodulator with Cascade Catalytic Activities to Reprogram Endoplasmic Reticulum Stress-Mediated Immunosuppression for Enhancing Anti-Tumor Immunotherapy
errBiomaterials
IF12.9
err2026-05-28
err0
PREAI
errXiao-Kang Jin; Ting Pan; Zi-Han Xu; Shi-Man Zhang; Hong Chen; Yu-Zhang Wang; Yan Xiao; Jia-Jing Dai; Si-Xue Cheng; Chuan-Jun Liu; Xian-Zheng Zhang
errShare
errSave
A Tumor-Targeted Cascade Catalytic Nanoreactor for Microenvironment Remodeling and Photodynamic Immunotherapy
errAdvanced Healthcare Materials
IF9.6
err2026-04-30
err0
PREAI
errXiang-Yu Ma; Ting Pan; Xiao-Kang Jin; Shi-Man Zhang; Xuan Zeng; Xian-Zheng Zhang
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errSave
A Photothermal-Responsive PRP-Loaded Hydrogel Engineered With Composite Nanobottle for Controllable Delivery of Growth Factors and Multifunctional Therapy of Diabetic Wounds
errAdvanced Science
IF14.1
err2026-02-24
err0
errOAAI
errWen-Qiang Qu; Hui-Yun Gu; Si-Min Zeng; Chang-Jiang Liu; Xiao Yan; Ting Pan; Chao Jian; Xian-Zheng Zhang; Ai-Xi Yu
errShare
errSave
Engineered Lactobacillus reuteri for scavenging reactive oxygen species and modulating oral microflora in periodontitis therapy
errInternational Journal of Oral Science
IF12.2
err2026-02-10
err0
errOAAI
errYuqiang Wang; Ying Tang; Qianxiao Huang; Jiaxin An; Yueli Zhou; Hongye Yang; Fangfang Song; Xianzheng Zhang; Cui Huang
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errSave
An Intracellular Gelated Macrophage-Based Vaccine for Tumor Immunotherapy
errACS Nano
IF16
err2026-02-10
err0
PREAI
errJia-Xin An; Ying Tang; Jinlian He; You-Teng Qin; Xian-Zheng Zhang
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errSave
Bone-Homing Cellular Backpacks Integrating Metabolic Intervention and Synergistic Osteogenesis to Treat Bone Metastasis and Promote Diabetic Bone Repair
errAdvanced Functional Materials
IF19
err2026-01-15
err0
PREAI
errChang-Jiang Liu; Wen-Qiang Qu; Dong Zhang; Hui-Yun Gu; Hai-Heng Peng; Xian-Zheng Zhang; Ai-Xi Yu
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errSave
Nanomedicine for targeting cancer-associated fibroblasts in cancer therapy
errTheranostics
IF13.3
err2026-01-01
err5
PREAI
errChen, Zi-Yi; Liu, Han-Zhe; Shang, Zheng-Jun; Luo, Guo-Feng; Zhang, Xian-Zheng
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errSave
Chain effects of landslide activity intensity decay on landslide sediment transfer and debris flow activity
errCanadian Geotechnical Journal
IF3.5
err2026-01-01
err0
PREAI
errXiong, Jiang; Zeng, Lu; Tang, Chuan; Chen, Huayong; Chen, Jiangang; Tang, Chenxiao; Gong, Lingfeng; Chen, Ming; Zhang, Xianzheng; Shi, Qingyun
errShare
errSave
Senescence Reprogramming Unleashes Tumor Immune Surveillance via Coordinated Gene Modulation
errADVANCED MATERIALS
IF26.8
err2025-12-01
err0
PREAI
errZhao, Kai; Yan, Yu; Dong, Bao-Ting; Pan, Shan-Shan; Zhang, Xian-Zheng
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errSave
Chirality-Directed Strategy to Overcome Tumor Resistance to Cuproptosis and Enhance Cuproptosis-Immunotherapy
errSmall Structures
IF11.3
err2025-11-24
err0
errOAAI
errHao Zhou; Xiaoyang Zhang; Yu-Zhang Wang; Shi-Man Zhang; Hong Chen; Xiao Yan; Chi-Hui Yang; Wei-Hai Chen; Xian-Zheng Zhang
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errSave
Biomimetic built-in nanoenzymes mitigate brain damage and enhance neurological recovery in ischemic stroke
errChemical Engineering Journal
IF13.2
err2025-11-20
err0
PREAI
errNa Jiang; Wen-long Liu; Yao Wang; Wei Wang; Jinlian He; Minjie Xie; Jun Feng; Xian-Zheng Zhang
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errSave
Point-of-Care Diagnosis of Respiratory Viruses at Single-Nucleotide Resolution with an Autocatalytic Rolling Circle Amplification System
errAngewandte Chemie International Edition
IF16.9
err2025-11-20
err0
PREAI
errJinhua Shang; Yuan Wang; Ya Pang; Mengdi Yu; Yifei Wang; Prof. Songmei Liu; Prof. Xianzheng Zhang; Prof. Fuan Wang
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errSave
Living materials for gas therapy
errAdvanced Drug Delivery Reviews
IF17.6
err2025-11-15
err0
PREAI
errPei Pan; Tao Liu; Lu Zhang; Xian-Zheng Zhang
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errSave
Occurrence and determinants of multi-pesticide residues in bats: A case study in Yunnan Province, China
errEnvironmental Pollution
IF7.3
err2025-11-08
err0
PREAI
errYujuan Wang; Xiaobin Huang; Xianzheng Zhang; Jinting Yang; Yingying Liu; Can Ke; Peter J. Taylor; Jiang Feng; Tinglei Jiang
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errSave
A Candidalysin-Neutralizing Nanomodulator Enhances Colorectal Cancer Immunotherapy by Targeting Fungi–Macrophage Crosstalk
errJournal of the American Chemical Society
IF15.6
err2025-11-07
err0
PREAI
errYu Yan; Kai Zhao; Shan-Shan Pan; Yu-Liang Sun; Zhi-Yong Rao; Xian-Zheng Zhang
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errSave
Autonomous Exponential Amplification via Rolling Circle-DNAzyme Feedback Programming
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2025-11-01
err0
PREAI
errShang, Jinhua; Yu, Mengdi; Wang, Yifei; Yu, Shanshan; Zhang, Xianzheng; Wang, Fuan; Li, Yingfu
errShare
errSave

Research Directions

生物医用高分子深入的研究。围绕高分子载体高效负载智能响应及功能协同的科学问题，提出了“肿瘤触发靶向”“信封型”功能协同“活性生物材料”等新方法新策略，精准高效地将药物传递到肿瘤组织，显著提高疗效降低药物毒副作用，以及克服肿瘤的多药耐药性等
Co-authors
Cooperation Journals
B
Ben Zhong Tang
H-index: 212 · Papers: 4.2K
王小岗 cover
王小岗 (Xiaogang Wang)
H-index: 208 · Papers: 4.1K
仉华 cover
仉华 (Hua Zhang)
H-index: 205 · Papers: 2.7K
张莉娜 cover
张莉娜 (Lina Zhang)
H-index: 126 · Papers: 1.7K
黄
黄飞 (Fei Huang)
H-index: 121 · Papers: 1.4K
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