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Adam Helms

university of michigan
H-index:33
Citation Count:4,382
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Evaluating constrained and unconstrained mixture frameworks for predicting engineered heart tissue mechanics

评估约束和非约束混合框架在预测工程心脏组织力学中的应用

Acta Biomaterialia
IF9.6
2026-06-011
PRE
Jilberto, Javiera; DePalma, Samuel J.; Ntim, David; Kobeissi, Hiba; Lejeune, Emma; Helms, Adam; Baker, Brendon M.; Nordsletten, David
Recruitment of transcriptional effectors by Cas9 creates cis-regulatory elements and demonstrates distance-dependent transcriptional regulation

Cas9招募转录效应因子形成顺式调控元件，并证明了距离依赖性的转录调控。

iScience
IF4.1
2025-11-120
OAAI
Jubran Boulos; Arkadiy K. Golov; Nadav Keren; Itai Erlich; Nardeen Shehadeh; Nili Avidan; Hagai Kariti; Omer Sadeh; Lilac Haimovich-Caspi; Adam Helms; Noam Kaplan; Izhak Kehat
Altered cardiac excitability and arrhythmia in models of SCN1B-linked developmental and epileptic encephalopathy

SCN1B相关发育性癫痫性脑病模型中心脏兴奋性和心律失常的改变

JCI INSIGHT
IF6.1
2025-09-091
OA
Ramos-Mondragon, Roberto; Wang, Shuyun; Edokobi, Nnamdi; Liu, Qinghua; Qiao, Xiaotan; Shih, Maya; Dang, Louis T.; Tsan, Yao-Chang; Sterbova, Katalin; Helms, Adam S.; Weckhuysen, Sarah; Lopez-Santiago, Luis F.; Parent, Jack M.; Isom, Lori L.
Sex-Specific Clinical and Genetic Factors Associated With Adverse Outcomes in Hypertrophic Cardiomyopathy
CIRCULATION-GENOMIC AND PRECISION MEDICINE
IF5.5
2025-02-010
PRE
Butters, Alexandra; Arnott, Clare; Sweeting, Joanna; Claggett, Brian; Cuomo, Anna S. E.; Abrams, Dominic; Ashley, Euan A.; Day, Sharlene M.; Helms, Adam S.; Lampert, Rachel; Lin, Kim Y.; Michels, Michelle; Miller, Erin M.; Olivotto, Iacopo; Owens, Anjali; Parikh, Victoria N.; Pereira, Alexandre C.; Rossano, Joseph W.; Ryan, Thomas D.; Saberi, Sara; Stendahl, John C.; Ware, James S.; Atherton, John; Semsarian, Christopher; Lakdawala, Neal K.; Ho, Carolyn Y.; Ingles, Jodie
Desmoplakin Cardiomyopathy: Role of Inflammation and Potential Role of Disease-Modifying Therapies
CURRENT CARDIOLOGY REPORTS
IF3.3
2025-01-090
PRE
Gasperetti, Alessio; Carrick, Richard T.; Muller, Steven; Murray, Brittney; Adamo, Luigi; Bauce, Barbara; Mcnally, Elizabeth; Helms, Adam
Matrix Architecture and Mechanics Regulate Myofibril Organization, Costamere Assembly, and Contractility in Engineered Myocardial Microtissues

基质结构和力学调节工程化心肌微组织中的肌原纤维组织，睾丸组装和收缩力

ADVANCED SCIENCE
IF14.1
2024-11-180
OAAI
DePalma, Samuel J.; Jilberto, Javiera; Stis, Austin E.; Huang, Darcy D.; Lo, Jason; Davidson, Christopher D.; Chowdhury, Aamilah; Kent III, Robert N.; Jewett, Maggie E.; Kobeissi, Hiba; Chen, Christopher S.; Lejeune, Emma; Helms, Adam S.; Nordsletten, David A.; Baker, Brendon M.
The Impact of Genotype in Dilated and Arrhythmogenic Cardiomyopathy: Insights from the SHaRE Registry

扩张型与心律失常性心肌病中的基因型影响：SHaRE注册研究的见解

CIRCULATION
IF38.6
2024-11-120
PRE
Padalia, Kishan; Slaven, Sarah; Medo, Kristen; Graw, Sharon; Claggett, Brian; Bundgaard, Henning; Helms, Adam; Heymans, Stephane; Ho, Carolyn; Khan, Sadiya; Lakdawala, Neal; Olivotto, Iacopo; Owens, Anjali; Prasad, Sanjay; Axelsson, Anna; Reza, Nosheen; Shore, Supriya; Sinagra, Gianfranco; Tayal, Upasana; Verdonschot, Job; Wheeler, Matthew; Taylor, Matthew; Merlo, Marco; Fornaro, Alessandra; Parikh, Victoria; Wilsbacher, Lisa; Mestroni, Luisa
Social Determinants of Health and Outcomes in Patients with Hypertrophic Cardiomyopathy in the Sarcomeric Human Cardiomyopathy Registry (SHaRe)

肌节性心肌病注册研究（SHaRe）中肥厚型心肌病患者的健康社会决定因素与结局

CIRCULATION
IF38.6
2024-11-120
PRE
Hafeez, Neha; Claggett, Brian; Owens, Anjali; Helms, Adam; Saberi, Sara; Lampert, Rachel; Stendahl, John; Ashley, Euan; Parikh, Victoria; Lakdawala, Neal; Ingles, Jodie; Olivotto, Iacopo; Ho, Carolyn; Taylor, Matthew; Khan, Sadiya; Day, Sharlene
Long-Term Outcomes After Septal Reduction Therapies in Obstructive Hypertrophic Cardiomyopathy: Insights From the SHARE Registry
CIRCULATION
IF38.6
2024-10-220
PRE
Maurizi, Niccolo; Antiochos, Panagiotis; Owens, Anjali; Lakdwala, Neal; Saberi, Sara; Russell, Mark W.; Fumagalli, Carlo; Skalidis, Ioannis; Lin, Kimberly Y.; Nathan, Ashwin S.; De Feria Alsina, Alejandro; Reza, Nosheen; Stendahl, John C.; Abrams, Dominic; Semsarian, Christopher; Clagget, Brian; Lampert, Rachel; Wheeler, Matthew; Parikh, Victoria N.; Ashley, Euan; Michels, Michelle; Rossano, Joseph; Ryan, Thomas D.; Ingles, Jodie; Ware, James; Ho, Carolyn Y.; Helms, Adam S.; Day, Sharlene M.; Olivotto, Iacopo
Clinical features and outcomes in carriers of pathogenic desmoplakin variants
EUROPEAN HEART JOURNAL
IF35.6
2024-09-171
OAAI
Gasperetti, Alessio; Carrick, Richard T.; Protonotarios, Alexandros; Murray, Brittney; Laredo, Mikael; van der Schaaf, Iris; Lekanne, Ronald H.; Syrris, Petros; Cannie, Douglas; Tichnell, Crystal; Cappelletto, Chiara; Gigli, Marta; Medo, Kristen; Saguner, Ardan M.; Duru, Firat; Gilotra, Nisha A.; Zimmerman, Stefan; Hylind, Robyn; Abrams, Dominic J.; Lakdawala, Neal K.; Cadrin-Tourigny, Julia; Targetti, Mattia; Olivotto, Iacopo; Graziosi, Maddalena; Cox, Moniek; Biagini, Elena; Charron, Philippe; Casella, Michela; Tondo, Claudio; Yazdani, Momina; Ware, James S.; Prasad, Sanjay K.; Calo, Leonardo; Smith, Eric D.; Helms, Adam S.; Hespe, Sophie; Ingles, Jodie; Tandri, Harikrishna; Ader, Flavie; Peretto, Giovanni; Peters, Stacey; Horton, Ari; Yao, Jess; Dittmann, Sven; Schulze-Bahr, Eric; Qureshi, Maria; Young, Katelyn; Carruth, Eric D.; Haggerty, Chris; Parikh, Victoria N.; Taylor, Matthew; Mestroni, Luisa; Wilde, Arthur; Sinagra, Gianfranco; Merlo, Marco; Gandjbakhch, Estelle; van Tintelen, J. Peter; te Riele, Anneline S. J. M.; Elliott, Perry M.; Calkins, Hugh; James, Cynthia A.
Development of a Novel Biallelic, Haploinsufficient Mouse Model of MYBPC3 Related Hypertrophic Cardiomyopathy
CIRCULATION RESEARCH
IF16.2
2024-08-020
PRE
Meisner, Joshua; Bullard, Abbey; Friedline, Sabrina; Rechsteiner, Olivia; Previs, Michael; Helms, Adam
A novel tool for arrhythmic risk stratification in desmoplakin gene variant carriers
EUROPEAN HEART JOURNAL
IF35.6
2024-07-166
OAAI
Carrick, Richard T.; Gasperetti, Alessio; Protonotarios, Alexandros; Murray, Brittney; Laredo, Mikael; van der Schaaf, Iris; Dooijes, Dennis; Syrris, Petros; Cannie, Douglas; Tichnell, Crystal; Gilotra, Nisha A.; Cappelletto, Chiara; Medo, Kristen; Saguner, Ardan M.; Duru, Firat; Hylind, Robyn J.; Abrams, Dominic J.; Lakdawala, Neal K.; Cadrin-Tourigny, Julia; Targetti, Mattia; Olivotto, Iacopo; Graziosi, Maddalena; Cox, Moniek; Biagini, Elena; Charron, Philippe; Compagnucci, Paolo; Casella, Michela; Conte, Giulio; Tondo, Claudio; Yazdani, Momina; Ware, James S.; Prasad, Sanjay K.; Calo, Leonardo; Smith, Eric D.; Helms, Adam S.; Hespe, Sophie; Ingles, Jodie; Tandri, Harikrishna; Ader, Flavie; Peretto, Giovanni; Peters, Stacey; Horton, Ari; Yao, Jessica; Schulze-Bahr, Eric; Dittman, Sven; Carruth, Eric D.; Young, Katelyn; Qureshi, Maria; Haggerty, Chris; Parikh, Victoria N.; Taylor, Matthew; Mestroni, Luisa; Wilde, Arthur; Sinagra, Gianfranco; Merlo, Marco; Gandjbakhch, Estelle; van Tintelen, J. Peter; te Riele, Anneline S. J. M.; Elliot, Perry; Calkins, Hugh; Wu, Katherine C.; James, Cynthia A.
Imaging Features of Arrhythmogenic Cardiomyopathies
RADIOGRAPHICS
IF5.5
2024-04-010
PRE
Galizia, Mauricio S.; Attili, Anil K.; Truesdell, William R.; Smith, Eric D.; Helms, Adam S.; Sulaiman, Abdulbaset M. A.; Madamanchi, Chaitanya; Agarwal, Prachi P.
Sex and Gene Based Differences in Age Related Penetrance of Dilated and Arrhythmogenic Cardiomyopathy
CIRCULATION
IF38.6
2023-11-070
PRE
Bart, Nicole K.; Stroeks, Sophie; Khan, Sadiya S.; Reza, Nosheen; Olivotto, Iacopo; Vissing, Christoffer; Sinnette, Corine; Owens, Anjali T.; Fornaro, Alessandra; Mestroni, Luisa; Taylor, Matthew; Helms, Adam S.; Prasad, Sanjay K.; Saberi, Sara; Shore, Supriya; Verdonschot, Job; Sinagra, Gianfranco; Merlo, Marco; Gigli, Marta; Wilsbacher, Lisa D.; Heymans, Stephane; Wheeler, Matthew
An Unbiased Screen Identified the Hsp70-BAG3 Complex as a Regulator of Myosin-Binding Protein C3
JACC-BASIC TO TRANSLATIONAL SCIENCE
IF7.2
2023-09-011
OA
Thompson, Andrea D.; Wagner, Marcus J.; Rodriguez, Juliani; Malhotra, Alok; Vander Roest, Steve; Lilienthal, Ulla; Shao, Hao; Vignesh, Mathav; Weber, Keely; Yob, Jaime M.; Prosser, Benjamin L.; Helms, Adam S.; Gestwicki, Jason E.; Ginsburg, David; Day, Sharlene M.
Left Ventricular Systolic Dysfunction in Patients Diagnosed With Hypertrophic Cardiomyopathy During Childhood: Insights From the SHaRe Registry
CIRCULATION
IF38.6
2023-08-016
OAAI
Alaiwi, Sarah Abou; Roston, Thomas M.; Marstrand, Peter; Claggett, Brian Lee; Parikh, Victoria N.; Helms, Adam S.; Ingles, Jodie; Lampert, Rachel; Lakdawala, Neal K.; Michels, Michelle; Owens, Anjali T.; Rossano, Joseph W.; Saberi, Sara; Abrams, Dominic J.; Ashley, Euan A.; Semsarian, Christopher; Stendahl, John C.; Ware, James S.; Miller, Erin; Ryan, Thomas D.; Russell, Mark W.; Day, Sharlene M.; Olivotto, Iacopo; Vissing, Christoffer R.; Ho, Carolyn Y. Y.
Left and Right PVC-Induced Ventricular Dysfunction
JACC-CLINICAL ELECTROPHYSIOLOGY
IF7.7
2023-02-014
OAAI
Huntrakul, Anurut; Helms, Adam; Attili, Anil; Agarwal, Prachi P.; Ghannam, Michael; Liang, Jackson J.; Latchamsetty, Rakesh; Jongnarangsin, Krit; Morady, Fred; Bogun, Frank
Probabilistic integration of transcriptome-wide association studies and colocalization analysis identifies key molecular pathways of complex traits
AMERICAN JOURNAL OF HUMAN GENETICS
IF8.1
2023-01-0110
OAAI
Okamoto, Jeffrey; Wang, Lijia; Yin, Xianyong; Luca, Francesca; Pique-Regi, Roger; Helms, Adam; Im, Hae Kyung; Morrison, Jean; Wen, Xiaoquan
Impact of SARS-Cov-2 infection in patients with hypertrophic cardiomyopathy: results of an international multicentre registry
ESC HEART FAILURE
IF3.7
2022-06-038
OA
Gimeno, Juan R.; Olivotto, Iacopo; Isabel Rodriguez, Ana; Ho, Carolyn Y.; Fernandez, Adrian; Quiroga, Alejandro; Angeles Espinosa, Mari; Gomez-Gonzalez, Cristina; Robledo, Maria; Tojal-Sierra, Lucas; Day, Sharlene M.; Owens, Anjali; Barriales-Villa, Roberto; Maria Larranaga, Jose; Rodriguez-Palomares, Jose; Gonzalez-del-Hoyo, Maribel; Piqueras-Flores, Jesus; Reza, Nosheen; Chumakova, Olga; Ashley, Euan A.; Parikh, Victoria; Wheeler, Matthew; Jacoby, Daniel; Pereira, Alexandre C.; Saberi, Sara; Helms, Adam S.; Villacorta, Eduardo; Gallego-Delgado, Maria; Castro, Daniel; Dominguez, Fernando; Ripoll-Vera, Tomas; Zorio-Grima, Esther; Sanchez-Martinez, Jose Carlos; Garcia-Alvarez, Ana; Arbelo, Elena; Victoria Mogollon, Maria; Fuentes-Canamero, Maria Eugenia; Grande, Elias; Pena, Carlos; Monserrat, Lorenzo; Lakdawala, Neal K.
Translation of New and Emerging Therapies for Genetic Cardiomyopathies
JACC-BASIC TO TRANSLATIONAL SCIENCE
IF7.2
2022-01-0135
OA
Helms, Adam S.; Thompson, Andrea D.; Day, Sharlene M.

Research Directions

The data has not been retrieved yet.
S
Sharlene M. Day
H-index:56Papers:259Citations:1.2万
I
Iacopo Olivotto
H-index:92Papers:767Citations:3.8万
S
Sara Saberi
H-index:35Papers:170Citations:7,083
E
Euan A. Ashley
H-index:105Papers:783Citations:4.2万
N
Neal K. Lakdawala
H-index:49Papers:244Citations:1.2万
C
Carolyn Y. Ho
H-index:74Papers:297Citations:1.8万
J
James S. Ware
H-index:84Papers:535Citations:6.1万
J
Jodie Ingles
H-index:54Papers:400Citations:1.5万
D
Daniel Jacoby
H-index:53Papers:310Citations:1.0万
M
Michelle Michels
H-index:50Papers:246Citations:8,999