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G

Garrett M. Frampton

foundation medicine inc.

86H-index
651Paper Count
4.3WCitation Count
Published Papers 132
Publication Date
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U2AF1 mutations rescue deleterious exon skipping induced by KRAS mutations
errNature Genetics
IF29
err2026-07-01
err0
PREAI
errDavid M. Walter; Katherine Cho; Smruthy Sivakumar; Daniel Denney; Iris T. Lee; Anders B. Dohlman; Jakob M. Heinz; Ethan Shurberg; Kevin X. Jiang; Akansha A. Gupta; Garrett M. Frampton; Matthew Meyerson
errShare
errSave
Phenotypic POLE variant classification identifies patients who may have favorable prognosis and benefit from immunotherapy
errthe journal of molecular diagnostics
IF0
err2026-01-02
err0
PREAI
errRachel B. Keller-Evans; Zoe Fleischmann; Smruthy Sivakumar; Radwa Sharaf; Erik A. Williams; Benjamin Kaplan; Ethan S. Sokol; Alexa B. Schrock; Hanna Tukachinsky; Douglas A. Mata; Tyler Janovitz; Douglas I. Lin; Lei Zhong; Lyle Lopez; Nimesh R. Patel; Garrett M. Frampton; Geoffrey R. Oxnard; Julia A. Elvin; Brennan Decker
errShare
errSave
Analytical validation of a homologous recombination deficiency signature (HRDsig) in pan-tumor tissue samples
errPLOS ONE
IF2.6
err2025-11-17
err0
PREAI
errLi, Wenshu; Leibowitz, Jeffrey A.; Wang, Shuoguo; Walker, Louisa; Xu, Chang; Chen, Kuei-Ting; Schrock, Alexa B.; Hughes, Jason; Patel, Nimesh; Elvin, Julia A.; Ritterhouse, Lauren L.; Sokol, Ethan; Frampton, Garrett; Dennis, Lucas; Yilmazel, Bahar; Decker, Brennan
errShare
errSave
Association between ancestry and tumor somatic mutations in a large national cohort of women with breast cancer
errnpj Breast Cancer
IF7.6
err2025-10-29
err0
errOAAI
errKirkpatrick B. Fergus; Justin Newberg; Ray Greenstein; Laura Fejerman; Luis Carvajal-Carmona; Eric Collisson; Niharika Dixit; Garrett Frampton; Franklin W. Huang; Susan L. Neuhausen; Elad Ziv
errShare
errSave
Meta-analysis reveals differences in somatic alterations by genetic ancestry across common cancers
errNature Genetics
IF29
err2025-10-16
err0
errOAAI
errSetor Amuzu; Amy X. Xie; Xuechun Bai; Kelly R. Pekala; Nicholas A. Pickersgill; David Ma; Tomin Perea-Chamblee; Kanika Arora; Walid K. Chatila; Andriy Derkach; Ronglai Shen; Garrett M. Frampton; Michael Berger; Nikolaus Schultz; Justin Y. Newberg; Jian Carrot-Zhang
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errSave
Meta-analysis reveals differences in somatic alterations by genetic ancestry across common cancers
errCANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
IF3.4
err2024-09-21
err0
PREAI
errAmuzu, Setor; Xie, Amy; Bai, Xuechun; Pekala, Kelly R.; Ma, David; Perea-Chamblee, Tomin; Aurora, Kanika; Frampton, Garrett; Berger, Michael; Schultz, Nikolaus; Newberg, Justin Y.; Carrot-Zhang, Jian
errShare
errSave
Investigating digital pathology tumor microenvironment features for immunotherapy outcome in patients with advanced non-small cell lung cancer
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errEbot, Ericka M.; Chen, Kuei-Ting; Biggs, Mikayla; Lin, Douglas I.; Elvin, Julia A.; Frampton, Garrett M.; Pao, James J.
errShare
errSave
Real-world pan-cancer landscape of frameshift mutations and their role in predicting responses to immune checkpoint inhibitors in cancers with low tumor mutational burden
errJOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
err2023-08-16
err6
errOAAI
errFlorou, Vaia; Floudas, Charalampos S.; Maoz, Asaf; Naqash, Abdul Rafeh; Norton, Carter; Tan, Aik Choon; Sokol, Ethan S.; Frampton, Garrett; Soares, Heloisa P.; Puri, Sonam; Swami, Umang; Wilky, Breelyn; Hosein, Peter; Trent, Jonathan; Lopes, Gilberto de Lima; Park, Wungki; Garrido-Laguna, Ignacio
errShare
errSave
Novel SOX10 indel mutations drive schwannomas through impaired transactivation of myelination gene programs
errNEURO-ONCOLOGY
IF13.4
err2023-07-12
err9
errOAAI
errWilliams, Erik A.; Ravindranathan, Ajay; Gupta, Rohit; Stevers, Nicholas O.; Suwala, Abigail K.; Hong, Chibo; Kim, Somang; Yuan, Jimmy Bo; Wu, Jasper; Barreto, Jairo; Lucas, Calixto-Hope G.; Chan, Emily; Pekmezci, Melike; LeBoit, Philip E.; Mully, Thaddeus; Perry, Arie; Bollen, Andrew; Van Ziffle, Jessica; Devine, W. Patrick; Reddy, Alyssa T.; Gupta, Nalin; Basnet, Kristen M.; Macaulay, Robert J. B.; Malafronte, Patrick; Lee, Han; Yong, William H.; Williams, Kevin Jon; Juratli, Tareq A.; Mata, Douglas A.; Huang, Richard S. P.; Hiemenz, Matthew C.; Pavlick, Dean C.; Frampton, Garrett M.; Janovitz, Tyler; Ross, Jeffrey S.; Chang, Susan M.; Berger, Mitchel S.; Jacques, Line; Song, Jun S.; Costello, Joseph F.; Solomon, David A.
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errSave
Comprehensive genomic profiling and treatment patterns across ancestries in advanced prostate cancer: a large-scale retrospective analysis
errLANCET DIGITAL HEALTH
IF24.1
err2023-06-01
err6
errOAAI
errSivakumar, Smruthy; Lee, Jessica K.; Moore, Jay A.; Hopkins, Julia; Newberg, Justin Y.; Madison, Russell; Graf, Ryon; Schrock, Alexa B.; Kobetz, Erin; Vince, Randy; Franco, Idalid; Seldon, Crystal; Frampton, Garrett M.; Mills, Jennifer; Venstrom, Jeffrey; Mahal, Brandon A.
errShare
errSave
Integrative Analysis of a Large Real-World Cohort of Small Cell Lung Cancer Identifies Distinct Genetic Subtypes and Insights into Histologic Transformation
errCANCER DISCOVERY
IF33.3
err2023-04-16
err41
errOAAI
errSivakumar, Smruthy; Moore, Jay A.; Montesion, Meagan; Sharaf, Radwa; Lin, Douglas I.; Colon, Caterina I.; Fleishmann, Zoe; Ebot, Ericka M.; Newberg, Justin Y.; Mills, Jennifer M.; Hegde, Priti S.; Pan, Quintin; Dowlati, Afshin; Frampton, Garrett M.; Sage, Julien; Lovly, Christine M.
errShare
errSave
Co-occurrence of alterations impacting telomere elongation
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errSharaf, Radwa; Murugesan, Karthikeyan; Frampton, Garrett M.; Albacker, Lee A.; Montesion, Meagan
errShare
errSave
Using Multilevel Regression and Poststratification (MRP) to inform estimates of biomarker prevalence for target populations of interest using linked clinico-genomic databases
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errSnider, Jeremy W.; Beal, Brennan; Bouzit, Lilia; Cho-Phan, Cheryl; Comment, Leah; Frampton, Garrett; Snow, Tamara
errShare
errSave
POLE-specific variant classification strategy is critical for identifying patients who may benefit from immunotherapy
errCANCER RESEARCH
IF16.6
err2023-04-04
err1
PREAI
errKeller, Rachel B.; Haberberger, James; Janovitz, Tyler; Schrock, Alexa B.; Tukachinsky, Hanna; Zhong, Lei; Mata, Douglas A.; Lopez, Lyle V.; Fleischmann, Zoe; Sharaf, Radwa; Sokol, Ethan S.; Frampton, Garrett M.; Patel, Nimesh R.; Lin, Douglas I.; Oxnard, Geoff R.; Williams, Erik A.; Elvin, Julia A.; Decker, Brennan
errShare
errSave
Comprehensive analysis of 3,600 small cell lung cancer cases reveals rare genetic subtypes and multiple mechanisms of histological transformation
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errSivakumar, Smruthy; Moore, Jay A.; Montesion, Meagan; Lin, Douglas I.; Fleischmann, Zoe; Ebot, Ericka M.; Newberg, Justin; Mills, Jennifer M.; Hegde, Priti S.; Frampton, Garrett M.; Sage, Julien; Lovly, Christine M.
errShare
errSave
Predicting EGFR mutational status from pathology images using a real-world dataset
errSCIENTIFIC REPORTS
IF3.9
err2023-03-16
err14
errOAAI
errPao, James J.; Biggs, Mikayla; Duncan, Daniel; Lin, Douglas I.; Davis, Richard; Huang, Richard S. P.; Ferguson, Donna; Janovitz, Tyler; Hiemenz, Matthew C.; Eddy, Nathanial R.; Lehnert, Erik; Cabili, Moran N.; Frampton, Garrett M.; Hegde, Priti S.; Albacker, Lee A.
errShare
errSave
Comprehensive pan-cancer genomic landscape of KRAS altered cancers and real-world outcomes in solid tumors
errNPJ PRECISION ONCOLOGY
IF8
err2022-12-09
err57
errOAAI
errLee, Jessica K.; Sivakumar, Smruthy; Schrock, Alexa B.; Madison, Russell; Fabrizio, David; Gjoerup, Ole; Ross, Jeffrey S.; Frampton, Garrett M.; Napalkov, Pavel; Montesion, Meagan; Schutzman, Jennifer L.; Ye, Xin; Hegde, Priti S.; Nagasaka, Misako; Oxnard, Geoffrey R.; Sokol, Ethan S.; Ou, Sai-Hong Ignatius; Shi, Zhen
errShare
errSave
Tissue and liquid biopsy profiling reveal convergent tumor evolution and therapy evasion in breast cancer
errNATURE COMMUNICATIONS
IF15.7
err2022-12-05
err18
errOAAI
errSivakumar, Smruthy; Jin, Dexter X.; Tukachinsky, Hanna; Murugesan, Karthikeyan; McGregor, Kimberly; Danziger, Natalie; Pavlick, Dean; Gjoerup, Ole; Ross, Jeffrey S.; Harmon, Robert; Chung, Jon; Decker, Brennan; Dennis, Lucas; Frampton, Garrett M.; Molinero, Luciana; Oesterreich, Steffi; Venstrom, Jeffrey M.; Oxnard, Geoffrey R.; Hegde, Priti S.; Sokol, Ethan S.
errShare
errSave
Deletions on 9p21 are associated with worse outcomes after anti-PD-1/PD-L1 monotherapy but not chemoimmunotherapy
errNPJ PRECISION ONCOLOGY
IF8
err2022-06-23
err15
errOAAI
errEbot, Ericka M.; Duncan, Daniel L.; Tolba, Khaled; Fabrizio, David; Frampton, Garrett M.; Comment, Leah A.; Albacker, Lee A.
errShare
errSave
Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma
errNATURE COMMUNICATIONS
IF15.7
err2022-06-15
err80
errOAAI
errGounder, Mrinal M.; Agaram, Narasimhan P.; Trabucco, Sally E.; Robinson, Victoria; Ferraro, Richard A.; Millis, Sherri Z.; Krishnan, Anita; Lee, Jessica; Attia, Steven; Abida, Wassim; Drilon, Alexander; Chi, Ping; D'Angelo, Sandra P.; Dickson, Mark A.; Keohan, Mary Lou; Kelly, Ciara M.; Agulnik, Mark; Chawla, Sant P.; Choy, Edwin; Chugh, Rashmi; Meyer, Christian F.; Myer, Parvathi A.; Moore, Jessica L.; Okimoto, Ross A.; Pollock, Raphael E.; Ravi, Vinod; Singh, Arun S.; Somaiah, Neeta; Wagner, Andrew J.; Healey, John H.; Frampton, Garrett M.; Venstrom, Jeffrey M.; Ross, Jeffrey S.; Ladanyi, Marc; Singer, Samuel; Brennan, Murray F.; Schwartz, Gary K.; Lazar, Alexander J.; Thomas, David M.; Maki, Robert G.; Tap, William D.; Ali, Siraj M.; Jin, Dexter X.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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Rudolf Jaenisch
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M
Marc Ladanyi
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Mark A. Rubin
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