Robert Hromas - Publications, H-index & Citations

Back

Robert Hromas

university of texas

63H-index

324Paper Count

1.5WCitation Count

Published Papers 92

Publication Date

Structural insight into how RAD51 paralog exchange regulates RAD51 filament formation

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2026-04-22

OAAI

Yashpal Rawal; Youngho Kwon; Lijia Jia; Eliza A. Ruben; Jae-Hoon Ji; Lijuan Guo; Caleb M. Stratton; Digant Nayak; Miriam Tovar; Qingming Fang; Mohd Azrin Jamalruddin; Shuo Zhou; Sahiti Kuppa; Shahrez Syed; Angela M. Jasper; Jeffrey N. Katz; Cody M. Rogers; Hardeep Kaur; Lorena Samentar; Weixing Zhao; Eloise Dray; Fang Zhang; Svetla Stoilova-McPhie; Alexander B. Taylor; Sandeep Burma; Manjeet K. Rao; David S. Libich; Robert Hromas; Alexander V. Mazin; Maria Jasin; Daohong Zhou; Kara A. Bernstein; Eric C. Greene; Elizabeth V. Wasmuth; Patrick Sung; Shaun K. Olsen

Save

Structural Basis for the Mechanism and Stability of the EEPD1 5’ Endonuclease

Journal of Biological Chemistry

IF3.9

2026-04-08

OAAI

Robert A. Hromas; Aruna S. Jaiswal; Anurag Misra; Yaxia Yuan; Daohong Zhou; John I. Beckman; Shailee Arya; Adhishree Chidambaram; Alexander B. Taylor; Wendell Griffith; Arunima Jaiswal; Elizabeth A. Williamson; Yogesh K. Gupta

Save

Author Correction: Structural insights into BCDX2 complex function in homologous recombination

Nature

IF48.5

2026-01-08

OAAI

Yashpal Rawal; Lijia Jia; Aviv Meir; Shuo Zhou; Hardeep Kaur; Eliza A. Ruben; Youngho Kwon; Kara A. Bernstein; Maria Jasin; Alexander B. Taylor; Sandeep Burma; Robert Hromas; Alexander V. Mazin; Weixing Zhao; Daohong Zhou; Elizabeth V. Wasmuth; Eric C. Greene; Patrick Sung; Shaun K. Olsen

Save

First in human phase 1 study of DT2216, a selective BCL-xL degrader, in patients with relapsed/refractory solid malignancies

Journal of Hematology & Oncology

IF40.4

2025-11-12

OAAI

Daruka Mahadevan; Minal Barve; Devalingam Mahalingam; Jay Parekh; Michael Kurman; James Strauss; Larry Tremaine; Robert Hromas; Joshua Sills; John McCulloch; John Harkey; Stacy Suberg; Lisa Zimmerman; Guangrong Zheng; Daohong Zhou

Save

CTC1-STN1-TEN1 controls DNA break repair pathway choice via DNA end resection blockade

Science

IF45.8

2025-05-22

PREAI

Cody M. Rogers; Hardeep Kaur; Michelle L. Swift; Vivek B. Raina; Shuo Zhou; Ajinkya S. Kawale; Shahrez Syed; Korilynn G. Kelly; Angela M. Jasper; Sameer Salunkhe; Youngho Kwon; Jeffrey Wang; Aida Badamchi Shabestari; James M. Daley; Adam Sacks; Maria E. Gaczynska; Pawel A. Osmulski; Yashpal Rawal; Nozomi Tomimatsu; Simon A. Gayther; Kate Lawrenson; Sandeep Burma; Elizabeth V. Wasmuth; Shaun K. Olsen; Weixing Zhao; Robert Hromas; David S. Libich; Alexander V. Mazin; Daohong Zhou; Eric C. Greene; Dipanjan Chowdhury; Patrick Sung

Save

Distinct roles of the two BRCA2 DNA-binding domains in DNA damage repair and replication fork preservation

CELL REPORTS

IF6.9

2025-05-01

OAAI

Neal, Francisco E.; Li, Wenjing; Uhrig, Mollie E.; Katz, Jeffrey N.; Syed, Shahrez; Sharma, Neelam; Dutta, Arijit; Burma, Sandeep; Hromas, Robert; Mazin, Alexander, V; Dray, Eloise; Libich, David S.; Olsen, Shaun K.; Wasmuth, Elizabeth, V; Zhao, Weixing; Sorensen, Claus S.; Wiese, Claudia; Kwon, Youngho; Sung, Patrick

Save

Epigenetic silencing of DNA sensing pathway by FOXM1 blocks stress ligand-dependent antitumor immunity and immune memory

NATURE COMMUNICATIONS

IF15.7

2025-04-28

OAAI

Timilsina, Santosh; Huang, Jian Yu; Abdelfattah, Nourhan; Medina, Daisy; Singh, Deepika; Abdulsahib, Shahad; Subbarayalu, Panneerdoss; Do, Trong Phat; Venkata, Prabhakar Pitta; Nirzhor, Saif; Prochnau, Jack; Bhandari, Mukund; Zheng, Siyuan; Chen, Yidong; Huang, Gang; Mukherjee, Neelam; Hromas, Robert; Sung, Patrick; Kaklamani, Virginia; Vadlamudi, Ratna; Zhang, Nu; Rao, Manjeet K.

Save

Targeting cIAP2 in a novel senolytic strategy prevents glioblastoma recurrence after radiotherapy

EMBO MOLECULAR MEDICINE

IF8.3

2025-02-19

OAAI

Tomimatsu, Nozomi; Di Cristofaro, Luis Fernando Macedo; Kanji, Suman; Samentar, Lorena; Jordan, Benjamin Russell; Kittler, Ralf; Habib, Amyn A.; Espindola-Netto, Jair Machado; Tchkonia, Tamara; Kirkland, James L.; Burns, Terry C.; Sarkaria, Jann N.; Gilbert, Andrea; Floyd, John R.; Hromas, Robert; Zhao, Weixing; Zhou, Daohong; Sung, Patrick; Mukherjee, Bipasha; Burma, Sandeep

Save

Colibactin Exerts Androgen-dependent and -independent Effects on Prostate Cancer

European Urology Oncology

IF9.3

2024-11-01

OAAI

Raag Agrawal; Sarah Al-Hiyari; Rupert Hugh-White; Robert Hromas; Yash Patel; Elizabeth A. Williamson; Mohammed F.E. Mootor; Alfredo Gonzalez; Jianmin Fu; Roni Haas; Madison Jordan; Brian L. Wickes; Ghouse Mohammed; Mao Tian; Molly J. Doris; Christian Jobin; Kevin M. Wernke; Yu Pan; Takafumi N. Yamaguchi; Seth B. Herzon; Paul C. Boutros; Michael A. Liss

Save

Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL

NATURE COMMUNICATIONS

IF15.7

2024-03-29

OAAI

Nayak, Digant; Lv, Dongwen; Yuan, Yaxia; Zhang, Peiyi; Hu, Wanyi; Nayak, Anindita; Ruben, Eliza A.; Lv, Zongyang; Sung, Patrick; Hromas, Robert; Zheng, Guangrong; Zhou, Daohong; Olsen, Shaun K.

Save

TATDN2 resolution of R-loops is required for survival of BRCA1-mutant cancer cells

NUCLEIC ACIDS RESEARCH

IF13.1

2023-11-11

OAAI

Jaiswal, Aruna S.; Dutta, Arijit; Srinivasan, Gayathri; Yuan, Yaxia; Zhou, Daohong; Shaheen, Montaser; Sadideen, Doraid T.; Kirby, Austin; Williamson, Elizabeth A.; Gupta, Yogesh K.; Olsen, Shaun K.; Xu, Mingjiang; Loranc, Eva; Mukhopadhyay, Pramiti; Pertsemlidis, Alexander; Bishop, Alexander J. R.; Sung, Patrick; Nickoloff, Jac A.; Hromas, Robert

Save

The RNA Demethylase ALKBH5 Maintains Endoplasmic Reticulum Homeostasis by Regulating UPR, Autophagy, and Mitochondrial Function

CELLS

IF5.2

2023-04-29

OAAI

Subbarayalu, Panneerdoss; Yadav, Pooja; Timilsina, Santosh; Medina, Daisy; Baxi, Kunal; Hromas, Robert; Vadlamudi, Ratna K.; Chen, Yidong; Sung, Patrick; Rao, Manjeet K.

Save

Emi1 Maintains Genomic Integrity during Zebrafish Embryogenesis and Cooperates with p53 in Tumor Suppression

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-21

OAAI

Rhodes, Jennifer; Amsterdam, Adam; Sanda, Takaomi; Moreau, Lisa A.; McKenna, Keith; Heinrichs, Stefan; Ganem, Neil J.; Ho, Karen W.; Neuberg, Donna S.; Johnston, Adam; Ahn, Yebin; Kutok, Jeffery L.; Hromas, Robert; Wray, Justin; Lee, Charles; Murphy, Carly; Radtke, Ina; Downing, James R.; Fleming, Mark D.; MacConaill, Laura E.; Amatruda, James F.; Gutierrez, Alejandro; Galinsky, Ilene; Stone, Richard M.; Ross, Eric A.; Pellman, David S.; Kanki, John P.; Look, A. Thomas

Save

Hematopoietic cytoplasmic adaptor protein Hem1 promotes osteoclast fusion and bone resorption in mice

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-02-01

OAAI

Wang, Xiaoyan; Shao, Lijian; Richardson, Kimberly K.; Ling, Wen; Warren, Aaron; Krager, Kimberly; Aykin-Burns, Nukhet; Hromas, Robert; Zhou, Daohong; Almeida, Maria; Kim, Ha-Neui

Save

DNA binding and RAD51 engagement by the BRCA2 C-terminus orchestrate DNA repair and replication fork preservation

NATURE COMMUNICATIONS

IF15.7

2023-01-26

OAAI

Kwon, Youngho; Rosner, Heike; Zhao, Weixing; Selemenakis, Platon; He, Zhuoling; Kawale, Ajinkya S.; Katz, Jeffrey N.; Rogers, Cody M.; Neal, Francisco E.; Shabestari, Aida Badamchi; Petrosius, Valdemaras; Singh, Akhilesh K.; Joel, Marina Z.; Lu, Lucy; Holloway, Stephen P.; Burma, Sandeep; Mukherjee, Bipasha; Hromas, Robert; Mazin, Alexander; Wiese, Claudia; Sorensen, Claus S.; Sung, Patrick

Save

EEPD1 promotes repair of oxidatively-stressed replication forks

NAR CANCER

IF3.2

2023-01-18

OAAI

Jaiswal, Aruna S.; Kim, Hyun-Suk; Scharer, Orlando D.; Sharma, Neelam; Williamson, Elizabeth A.; Srinivasan, Gayathri; Phillips, Linda; Kong, Kimi; Arya, Shailee; Misra, Anurag; Dutta, Arijit; Gupta, Yogesh; Walter, Christi A.; Burma, Sandeep; Narayan, Satya; Sung, Patrick; Nickoloff, Jac A.; Hromas, Robert

Save

Co-targeting BCL-XL and MCL-1 with DT2216 and AZD8055 synergistically inhibit small-cell lung cancer growth without causing on-target toxicities in mice

CELL DEATH DISCOVERY

IF7

2023-01-02

OAAI

Khan, Sajid; Kellish, Patrick; Connis, Nick; Thummuri, Dinesh; Wiegand, Janet; Zhang, Peiyi; Zhang, Xuan; Budamagunta, Vivekananda; Hua, Nan; Yang, Yang; De, Umasankar; Jin, Lingtao; Zhang, Weizhou; Zheng, Guangrong; Hromas, Robert; Hann, Christine; Zajac-Kaye, Maria; Kaye, Frederic J.; Zhou, Daohong

Save

Targeting aberrant replication and DNA repair events for treating breast cancers

COMMUNICATIONS BIOLOGY

IF5.1

2022-05-24

OAAI

Rajamanickam, Subapriya; Park, Jun Hyoung; Subbarayalu, Panneerdoss; Timilsina, Santosh; Bates, Kaitlyn; Yadav, Pooja; Nirzhor, Saif S. R.; Eedunuri, Vijay; Mohammad, Tabrez A.; Jung, Kwang Hwa; Onyeagucha, Benjamin; Abdelfattah, Nourhan; Benevides, Raymond; Lee, Grace; Chen, Yidong; Vadlamudi, Ratna; Brenner, Andrew; Kaklamani, Virginia; Jatoi, Ismail; Kuhn, John; Hromas, Robert; Gupta, Yogesh K.; Kaipparettu, Benny A.; Arbiser, Jack L.; Rao, Manjeet K.

Save

M6A RNA Methylation Regulates Histone Ubiquitination to Support Cancer Growth and Progression

CANCER RESEARCH

IF16.6

2022-03-18

OAAI

Yadav, Pooja; Subbarayalu, Panneerdoss; Medina, Daisy; Nirzhor, Saif; Timilsina, Santosh; Rajamanickam, Subapriya; Eedunuri, Vijay K.; Gupta, Yogesh; Zheng, Siyuan; Abdelfattah, Nourhan; Huang, Yufei; Vadlamudi, Ratna; Hromas, Robert; Meltzer, Paul; Houghton, Peter; Chen, Yidong; Rao, Manjeet K.

Save

Tumor Intrinsic PD-L1 Promotes DNA Repair in Distinct Cancers and Suppresses PARP Inhibitor-Induced Synthetic Lethality

CANCER RESEARCH

IF16.6

2022-03-03

OAAI

Kornepati, Anand V. R.; Boyd, Jacob T.; Murray, Clare E.; Saifetiarova, Julia; Avaios, Barbara de la Pena; Rogers, Cody M.; Bai, Haiyan; Padron, Alvaro S.; Liao, Yiji; Ontiveros, Carlos; Svatek, Robert S.; Hromas, Robert; Li, Rong; Hu, Yanfen; Conejo-Garcia, Jose R.; Vadlamudi, Ratna K.; Zhao, Weixing; Dray, Elose; Sung, Patrick; Curiel, Tyler J.

Save

Research Directions