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D

Douglas E. Vaughan

northwestern university

80H-index
339Paper Count
2.3WCitation Count
Published Papers 141
Publication Date
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Plasminogen activator inhibitor1 promotes aortic aging-like pathophysiologyin humans and mice
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2025-12-01
err0
errOAAI
errKhoddam, Alireza; Kalousdian, Anthony; Eren, Mesut; Soberanes, Saul; Decker, Andrew; Lux, Elizabeth J.; Zywicki, Benjamin W.; Dinh, Brian; Boztepe, Bedirhan; Cheema, Baljash S.; Cuda, Carla M.; Abdala-Valencia, Hiam; Sivakumar, Arun; Miyata, Toshio; Wilsbacher, Lisa D.; Vaughan, Douglas E.
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PAI-1 is a common driver of aging and diverse diseases
errBiomedical Journal
IF4.4
err2025-07-18
err0
errOAAI
errAlireza Khoddam; Toshio Miyata; Douglas Vaughan
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errSave
TRENDS IN EMBRYO DISPOSITION IN THE ERA OF PGT-A
errFertility and Sterility
IF7
err2025-06-27
err0
PREAI
errA. Huttler; D. Duvall; B. Morse; Q. Heyward; K. Patel; D. Sakkas; D. Vaughan; A. Penzias
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errSave
Two for the Price of One: Twins and Multiple Births Following a Natural vs. Programmed Single Frozen Blastocyst Transfer Cycle
errHUMAN REPRODUCTION
IF6.1
err2025-06-01
err0
errOAAI
errMeyers, A.; Mensah, V; Morse, B.; Sakkas, D.; Vaughan, D.
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errSave
A high proportion of immature oocytes in a cycle cohort does not impair embryo development or live birth rates following ICSI
errHUMAN REPRODUCTION
IF6.1
err2025-06-01
err0
errOAAI
errSakkas, D.; Sripada, V; Vaughan, D.; Morse, B.; Fouks, Y.
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errSave
Plasminogen Activator Inhibitor-1 (PAI-1) is an Essential Driver of Cardiovascular Aging in Mice
errCIRCULATION
IF38.6
err2023-11-07
err0
PREAI
errKalousdian, Anthony; Soberanes, Saul; Eren, Mesut; Jorgensen, Emily; Lux, Elizabeth; Wilsbacher, Lisa D.; Vaughan, Douglas E.
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errSave
Mouse model hints at pharmacogenomic strategies for stroke treatment in patients possessing a risk variant
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2023-09-15
err0
errOAAI
errVaughan, Douglas E.
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errSave
Pharmacological inhibition of plasminogen activator inhibitor-1 prevents memory deficits and reduces neuropathology in APP/PS1 mice
errPSYCHOPHARMACOLOGY
IF3.3
err2023-09-12
err2
PREAI
errRodriguez, Guadalupe; Eren, Mesut; Haupfear, Isabel; Viola, Kirsten L.; Cline, Erika N.; Miyata, Toshio; Klein, William L.; Vaughan, Douglas E.; Dong, Hongxin
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errSave
Associations between GrimAge acceleration and pulmonary function in the Coronary Artery Risk Development in Young Adults (CARDIA) study
errEPIGENOMICS
IF2.6
err2023-09-11
err0
errOAAI
errJoyce, Brian T.; Chen, Xuefen; Gao, Tao; Zheng, Yinan; Nannini, Drew R.; Liu, Lei; Henkle, Benjamin E.; Kalhan, Ravi; Washko, George; Kunisaki, Ken M.; Thyagarajan, Bharat; Vaughan, Douglas E.; Gross, Myron; Jacobs, David R.; Lloyd-Jones, Donald; Hou, Lifang
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errSave
Inequalities in urban greenness and epigenetic aging: Different associations by race and neighborhood socioeconomic status
errSCIENCE ADVANCES
IF12.5
err2023-06-30
err13
errOAAI
errKim, Kyeezu; Joyce, Brian T. T.; Nannini, Drew R. R.; Zheng, Yinan; Gordon-Larsen, Penny; Shikany, James M. M.; Lloyd-Jones, Donald M. M.; Hu, Ming; Nieuwenhuijsen, Mark J. J.; Vaughan, Douglas E. E.; Zhang, Kai; Hou, Lifang
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errSave
Inclusion of epigenetic age acceleration in oncological trials
errLANCET HEALTHY LONGEVITY
IF14.6
err2023-05-01
err0
PREAI
errMittal, Bharat B.; Vaughan, Douglas
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errSave
Cardiomyocyte PAI-1 influences the cardiac transcriptome and limits the extent of cardiac fibrosis in response to left ventricular pressure overload
errCELLULAR SIGNALLING
IF3.7
err2023-04-01
err4
errOAAI
errGhosh, Asish K.; Kalousdian, Anthony A.; Shang, Meng; Lux, Elizabeth; Eren, Mesut; Keating, Anna; Wilsbacher, Lisa D.; Vaughan, Douglas E.
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errSave
Assessment of Virological Contributions to COVID-19 Outcomes in a Longitudinal Cohort of Hospitalized Adults
errOPEN FORUM INFECTIOUS DISEASES
IF3.8
err2022-02-14
err8
errOAAI
errSimons, Lacy M.; Lorenzo-Redondo, Ramon; Gibson, Meg; Kinch, Sarah L.; Vandervaart, Jacob P.; Reiser, Nina L.; Eren, Mesut; Lux, Elizabeth; McNally, Elizabeth M.; Tambur, Anat R.; Vaughan, Douglas E.; Bachta, Kelly E. R.; Demonbreun, Alexis R.; Satchell, Karla J. F.; Achenbach, Chad J.; Ozer, Egon A.; Ison, Michael G.; Hultquist, Judd F.
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Pharmacological inhibition of PAI-1 alleviates cardiopulmonary pathologies induced by exposure to air pollutants PM2.5
errENVIRONMENTAL POLLUTION
IF7.3
err2021-10-01
err9
errOAAI
errGhosh, Asish K.; Soberanes, Saul; Lux, Elizabeth; Shang, Meng; Aillon, Raul Piseaux; Eren, Mesut; Budinger, G. R. Scott; Miyata, Toshio; Vaughan, Douglas E.
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errSave
Identification of Cardiac Fibrosis in Young Adults With a Homozygous Frameshift Variant in SERPINE1
errJAMA CARDIOLOGY
IF14.1
err2021-07-01
err13
errOAAI
errKhan, Sadiya S.; Shah, Sanjiv J.; Strande, Jennifer L.; Baldridge, Abigail S.; Flevaris, Panagiotis; Puckelwartz, Megan J.; McNally, Elizabeth N.; Rasmussen-Torvik, Laura J.; Lee, Daniel C.; Carr, James C.; Benefield, Brandon C.; Afzal, Muhammad Zeeshan; Heiman, Meadow; Gupta, Sweta; Shapiro, Amy D.; Vaughan, Douglas E.
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errSave
Inhibition of PAI-1 Promotes Lipolysis and Enhances Weight Loss in Obese Mice
errOBESITY
IF4.7
err2021-02-16
err7
errOAAI
errLevine, Joshua A.; Olivares, Shantel; Miyata, Toshio; Vaughan, Douglas E.; Henkel, Anne S.
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errSave
Role of PAI-1 in hepatic steatosis and dyslipidemia
errSCIENTIFIC REPORTS
IF3.9
err2021-01-11
err47
errOAAI
errLevine, Joshua A.; Oleaga, Carlota; Eren, Mesut; Amaral, Ansel P.; Shang, Meng; Lux, Elizabeth; Khan, Sadiya S.; Shah, Sanjiv J.; Omura, Yasuhiro; Pamir, Nathalie; Hay, Joshua; Barish, Grant; Miyata, Toshio; Tavori, Hagai; Fazio, Sergio; Vaughan, Douglas E.
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Effects of lisinopril treatment on the pathophysiology of PCOS and plasminogen activator inhibitor-1 concentrations in rats
errREPRODUCTIVE BIOMEDICINE ONLINE
IF3.5
err2021-01-01
err1
PREAI
errCoskun, Bugra; Ercan, Cihangir M.; Togrul, Cihan; Ozhamam, Esra U.; Coskun, Bora; Eren, Mesut; Vaughan, Douglas E.
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Illustrated State-of-the-Art Capsules of the ISTH 2020 Congress
errRESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS
IF3.4
err2020-07-01
err1
errOAAI
errAriens, Robert; Becattini, Cecilia; Bender, Markus; Bergmeier, Wolfgang; Castoldi, Elisabetta; Devreese, Katrien; Ellis, Martin; Gailani, David; Ignjatovic, Vera; James, Paula D.; Kerrigan, Steven; Lambert, Michele; Lee, Lai Heng; Levi, Marcel; Maugeri, Norma; Meijers, Joost; Melero-Martin, Juan; Michelson, Alan D.; Mingozzi, Federico; Neeves, Keith; Ni, Heyu; Olsson, Anna-Karin; Prohaszka, Zoltan; Ranson, Marie; Riva, Nicoletta; Senis, Yotis; van Ommen, Cornelia H.; Vaughan, Douglas E.; Weisel, John
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Association between plasminogen activator inhibitor-1 in young adulthood and nonalcoholic fatty liver disease in midlife: CARDIA
errLIVER INTERNATIONAL
IF5.2
err2020-03-11
err9
errOAAI
errCampbell, Patrick T.; VanWagner, Lisa B.; Colangelo, Laura A.; Lewis, Cora E.; Henkel, Anne; Ajmera, Veeral H.; Lloyd-Jones, Donald M.; Vaughan, Douglas E.; Khan, Sadiya S.
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Research Directions

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Co-authors
Cooperation Journals
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David R. Jacobs
H-index: 180 · Papers: 2.2K
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Bernard J. Gersh
H-index: 174 · Papers: 1.8K
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Mark Nieuwenhuijsen
H-index: 151 · Papers: 1.2K
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