Not logged in Dissecting and quantifying pancreatic cancer plasticity using single-cell multiomics, lineage tracing and functional genomics reveals novel mediators of therapy resistance Mehta, Arnav; Bi, Lynn; Yeramosu, Deepika; Bogaev, Michael; Jankowiak, Martin; Collins, Abigail; Al'Khafaji, Aziz; Parikh, Milan; Babadi, Mehrtash; Evans, Kyle; Bloemendal, Alex; Kunnes, Russell; Schwartz, Marc; Munson, Glen; Donnard, Elisa; Jones, Thouis R.; Stanger, Ben Z.; Shendure, Jay; Weissman, Jonathan; Ting, David T.; Aguirre, Andrew; Hacohen, Nir; Pe'er, Dana; Lander, Eric S. Share Save
The transcriptional and epigenetic regulation of epithelial-mesenchymal plasticity in patient-derived pancreatic cancer cell lines Yeramosu, Deepika; Bi, Lynn; Collins, Abigail; Bogaev, Mike; Jankowiak, Martin; Al'Khafaji, Aziz; Parikh, Milan; Babadi, Mehrtash; Bloemendal, Alex; Nagaraja, Surya; Jones, Ray; Shendure, Jay; Ting, David T.; Aguirre, Andrew; Hacohen, Nir; Pe'er, Dana; Lander, Eric S.; Mehta, Arnav Share Save
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Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases Weeks, Elle M. M.; Ulirsch, Jacob C. C.; Cheng, Nathan Y. Y.; Trippe, Brian L. L.; Fine, Rebecca S. S.; Miao, Jenkai; Patwardhan, Tejal A. A.; Kanai, Masahiro; Nasser, Joseph; Fulco, Charles P. P.; Tashman, Katherine C. C.; Aguet, Francois; Li, Taibo; Ordovas-Montanes, Jose; Smillie, Christopher S. S.; Biton, Moshe; Shalek, Alex K. K.; Ananthakrishnan, Ashwin N. N.; Xavier, Ramnik J. J.; Regev, Aviv; Gupta, Rajat M. M.; Lage, Kasper; Ardlie, Kristin G. G.; Hirschhorn, Joel N. N.; Lander, Eric S. S.; Engreitz, Jesse M. M.; Finucane, Hilary K. K. Share Save
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A platform for deep evolutionary profiling of cancer resistance Ravi, Arvind; Sontha, Sainikhil; Chowdhury, Maisha; Smigiel, Jacob; Rees, Matthew; Danysh, Brian; Roth, Jennifer; Parida, Laxmi; Lander, Eric; Getz, Gad Share Save
Gene Sequencing Identifies Perturbation in Nitric Oxide Signaling as a Nonlipid Molecular Subtype of Coronary Artery Disease Khera, Amit, V; Wang, Minxian; Chaffin, Mark; Emdin, Connor A.; Samani, Nilesh J.; Schunkert, Heribert; Watkins, Hugh; McPherson, Ruth; Erdmann, Jeanette; Elosua, Roberto; Boerwinkle, Eric; Ardissino, Diego; Butterworth, Adam S.; Di Angelantonio, Emanuele; Naheed, Aliya; Danesh, John; Chowdhury, Rajiv; Krumholz, Harlan M.; Sheu, Wayne H-H; Rich, Stephen S.; Rotter, Jerome, I; Chen, Yii-der Ida; Gabriel, Stacey; Lander, Eric S.; Saleheen, Danish; Kathiresan, Sekar Share Save
Neurocognitive trajectory and proteomic signature of inherited risk for Alzheimer's disease Paranjpe, Manish D.; Chaffin, Mark; Zahid, Sohail; Ritchie, Scott; Rotter, Jerome, I; Rich, Stephen S.; Gerszten, Robert; Guo, Xiuqing; Heckbert, Susan; Tracy, Russ; Danesh, John; Lander, Eric S.; Inouye, Michael; Kathiresan, Sekar; Butterworth, Adam S.; Khera, Amit, V Share Save
A patient-driven clinicogenomic partnership for metastatic prostate cancer Crowdis, Jett; Balch, Sara; Sterlin, Lauren; Thomas, Beena S.; Camp, Sabrina Y.; Dunphy, Michael; Anastasio, Elana; Shah, Shahrayz; Damon, Alyssa L.; Ramos, Rafael; Sosa, Delia M.; Small, Ilan K.; Tomson, Brett N.; Nguyen, Colleen M.; Mcgillicuddy, Mary; Chastain, Parker S.; He, Meng Xiao; Cheung, Alexander T. M.; Wankowicz, Stephanie; Tewari, Alok K.; Kim, Dewey; Aldubayan, Saud H.; Dowdye, Ayanah; Zola, Benjamin; Nowak, Joel; Manarite, Jan; Gunn, Idola Henry; Olson, Bryce; Lander, Eric S.; Painter, Corrie A.; Wagle, Nikhil; Van Allen, Eliezer M. Share Save
Inferring gene regulation from stochastic transcriptional variation across single cells at steady state Gupta, Anika; Martin-Rufino, Jorge D.; Jones, Thouis R.; Subramanian, Vidya; Qiu, Xiaojie; Grody, Emanuelle, I; Bloemendal, Alex; Weng, Chen; Niu, Sheng-Yong; Min, Kyung Hoi; Mehta, Arnav; Zhang, Kaite; Siraj, Layla; Khafaji, Aziz Al'; Sankaran, Vijay G.; Raychaudhuri, Soumya; Cleary, Brian; Grossman, Sharon; Lander, Eric S. Share Save
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Compressed sensing for highly efficient imaging transcriptomics Cleary, Brian; Simonton, Brooke; Bezney, Jon; Murray, Evan; Alam, Shahul; Sinha, Anubhav; Habibi, Ehsan; Marshall, Jamie; Lander, Eric S.; Chen, Fei; Regev, Aviv Share Save
A regulatory variant at 3q21.1 confers an increased pleiotropic risk for hyperglycemia and altered bone mineral density Sinnott-Armstrong, Nasa; Sousa, Isabel S.; Laber, Samantha; Rendina-Ruedy, Elizabeth; Dankel, Simon E. Nitter; Ferreira, Teresa; Mellgren, Gunnar; Karasik, David; Rivas, Manuel; Pritchard, Jonathan; Guntur, Anyonya R.; Cox, Roger D.; Lindgren, Cecilia M.; Hauner, Hans; Sallari, Richard; Rosen, Clifford J.; Hsu, Yi-Hsiang; Lander, Eric S.; Kiel, Douglas P.; Claussnitzer, Melina Share Save
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HyPR-seq: Single-cell quantification of chosen RNAs via hybridization and sequencing of DNA probes Marshall, Jamie L.; Doughty, Benjamin R.; Subramanian, Vidya; Guckelberger, Philine; Wang, Qingbo; Chen, Linlin M.; Rodriques, Samuel G.; Zhang, Kaite; Fulco, Charles P.; Nasser, Joseph; Grinkevich, Elizabeth J.; Noel, Teia; Mangiameli, Sarah; Bergman, Drew T.; Greka, Anna; Lander, Eric S.; Chen, Fei; Engreitz, Jesse M. Share Save
Delivery Mode Affects Stability of Early Infant Gut Microbiota Mitchell, Caroline M.; Mazzoni, Chiara; Hogstrom, Larson; Bryant, Allison; Bergerat, Agnes; Cher, Avital; Pochan, Shawna; Herman, Penelope; Carrigan, Maureen; Sharp, Karen; Huttenhower, Curtis; Lander, Eric S.; Vlamakis, Hera; Xavier, Ramnik J.; Yassour, Moran Share Save
Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions Fahed, Akl C.; Wang, Minxian; Homburger, Julian R.; Patel, Aniruddh P.; Bick, Alexander G.; Neben, Cynthia L.; Lai, Carmen; Brockman, Deanna; Philippakis, Anthony; Ellinor, Patrick T.; Cassa, Christopher A.; Lebo, Matthew; Ng, Kenney; Lander, Eric S.; Zhou, Alicia Y.; Kathiresan, Sekar; Khera, Amit V. Share Save
Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features Ray, John P.; de Boer, Carl G.; Fulco, Charles P.; Lareau, Caleb A.; Kanai, Masahiro; Ulirsch, Jacob C.; Tewhey, Ryan; Ludwig, Leif S.; Reilly, Steven K.; Bergman, Drew T.; Engreitz, Jesse M.; Issner, Robbyn; Finucane, Hilary K.; Lander, Eric S.; Regev, Aviv; Hacohen, Nir Share Save
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