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R

Robert C. Rintoul

university of cambridge

76H-index
319Paper Count
4.8WCitation Count
Published Papers 99
Publication Date
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A scalable deep-learning framework for cancer detection using cell-free DNA shallow whole-genome sequencing
errScience Advances
IF12.5
err2026-07-10
err0
errOAAI
errHaichao Wang; Paulius D. Mennea; Grainne McAndrew; Ozge Sonmezler; Dmitry S. Shcherbo; Emma-Jane Ditter; Sarah Østrup Jensen; Alessandra I. G. Buma; Christopher G. Smith; Zhao Cheng; Clare Harris; Rosalind. J. Cutts; Sarah Hrebien; Philip A. J. Crosbie; Pippa G. Corrie; Michel M. van den Heuvel; Amit Roshan; Frank McCaughan; Robert C. Rintoul; Florian Markowetz; Tommy Kaplan; Wendy N. Cooper; Hui Zhao; Nitzan Rosenfeld
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Developing carbon assimilation methods in duckweed for insights into photosynthesis and growth mechanisms
errPlant Physiology
IF6.9
err2026-05-26
err0
errOAAI
errRobert C Rintoul; Alison R Gill; Lorna McAusland; Erik H Murchie; Matthew Gilliham; Jenny C Mortimer; null
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Implementation of the NHS England Lung Cancer Screening Programme over 5 years
errNature Medicine
IF50
err2026-03-23
err0
errOAAI
errRichard W. Lee; Arjun Nair; Haval Balata; Charlotte Graham; Craig Parylo; Jessica Abell; Michael Woodall; Michael Lawrie; Sally Mouland; Kate Brain; Michelle Clark; Philip Crosbie; Anand Devaraj; Jesme Fox; Martin Grange; Sam M. Janes; Peter Johnson; Anne Mackie; Neal Navani; Samantha L. Quaife; Amelia Randle; Janette Rawlinson; Robert C. Rintoul; Liz Rochelle; Peter Sasieni; Matthew E. J. Callister; David R. Baldwin
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errSave
Treatment resistance to platinum-based chemotherapy in lung and ovarian cancer is driven by a targetable TGFβ senescent secretome
errNature Aging
IF19.4
err2026-02-03
err0
errOAAI
errEstela González-Gualda; Marika A. V. Reinius; David Macias; Samir Morsli; Jianfeng Ge; Ioana Olan; José Ezequiel Martín; Hui-Ling Ou; Muhamad Hartono; María Pilar Puerto-Camacho; Mary Denholm; Rosalind Kieran; Reuben Hoffmann; Mark Dane; Dimitris Veroutis; Guillermo Medrano; Francisca Mulero; Mercedes Jimenez-Linan; Ljiljana Fruk; Carla P. Martins; Mariano Barbacid; Vassilis Gorgoulis; James E. Korkola; Doris M. Rassl; Gary J. Doherty; Robert C. Rintoul; Masashi Narita; James D. Brenton; Daniel Muñoz-Espín
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Multi-cohort analysis identifies a blood-based immune transcriptomic signature for early lung cancer detection
errnpj Precision Oncology
IF8
err2025-07-19
err0
errOAAI
errHong Zheng; Aditya M. Rao; Ananthakrishnan Ganesan; Hyongsok Tom Soh; Bruce AJ Ponder; Robert C. Rintoul; Purvesh Khatri
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errSave
Recurrence prediction using circulating tumor DNA in patients with early-stage non-small cell lung cancer after treatment with curative intent: A retrospective validation study
errPLOS MEDICINE
IF9.9
err2025-04-15
err0
errOAAI
errSchuurbiers, Milou M. F.; Smith, Christopher G.; Hartemink, Koen J.; Rintoul, Robert C.; Gale, Davina; Mandos, Bas L. R.; Paterson, Anna L.; van den Broek, Dan; Rosenfeld, Nitzan; van den Heuvel, Michel M.
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Predictive value of circulating tumor DNA (ctDNA) before and shortly after curative treatment in early stage non-small cell lung cancer (NSCLC), and exploration of (pre-)analytical factors
errANNALS OF ONCOLOGY
IF65.4
err2024-09-01
err0
PREAI
errvan den Heuvel, M.; Smith, C. G.; Schuurbiers, M.; Hartemink, K.; Rintoul, R.; Monkhorst, K.; Van Den Broek, D.; Rosenfeld, N.
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errSave
Extended pleurectomy decortication and chemotherapy versus chemotherapy alone for pleural mesothelioma (MARS 2): a phase 3 randomised controlled trial
errLANCET RESPIRATORY MEDICINE
IF32.8
err2024-06-01
err21
errOAAI
errLim, Eric; Waller, David; Lau, Kelvin; Steele, Jeremy; Pope, Anthony; Ali, Clinton; Bilancia, Rocco; Keni, Manjusha; Popat, Sanjay; O'Brien, Mary; Tokaca, Nadza; Maskell, Nick; Stadon, Louise; Fennell, Dean; Nelson, Louise; Edwards, John; Tenconi, Sara; Socci, Laura; Rintoul, Robert C.; Wood, Kelly; Stone, Amanda; Muthukumar, Dakshinamoorthy; Ingle, Charlotte; Taylor, Paul; Cove-Smith, Laura; Califano, Raffaele; Summers, Yvonne; Tasigiannopoulos, Zacharias; Bille, Andrea; Shah, Riyaz; Fuller, Elizabeth; Macnair, Andrew; Shamash, Jonathan; Mansy, Talal; Milton, Richard; Koh, Pek; Ionescu, Andreea Alina; Treece, Sarah; Roy, Amy; Middleton, Gary; Kirk, Alan; Harris, Rosie A.; Ashton, Kate; Warnes, Barbara; Bridgeman, Emma; Joyce, Katherine; Mills, Nicola; Elliott, Daisy; Farrar, Nicola; Stokes, Elizabeth; Hughes, Vikki; Nicholson, Andrew G.; Rogers, Chris A.
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errSave
Single-cell transcriptomic analysis of human pleura reveals stromal heterogeneity and informs in vitro models of mesothelioma
errEUROPEAN RESPIRATORY JOURNAL
IF21
err2024-01-11
err0
errOAAI
errObacz, Joanna; Valer, Jose Antonio; Nibhani, Reshma; Adams, Taylor S.; Schupp, Jonas C.; Veale, Niki; Lewis-Wade, Amanah; Flint, Jasper; Hogan, John; Aresu, Giuseppe; Coonar, Aman S.; Peryt, Adam; Biffi, Giulia; Kaminski, Naftali; Francies, Hayley; Rassl, Doris M.; Garnett, Mathew J.; Rintoul, Robert C.; Marciniak, Stefan J.
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errSave
An update regarding the Meso-ORIGINS study: part of the PREDICT-Meso International Accelerator
errEUROPEAN RESPIRATORY JOURNAL
IF21
err2023-10-27
err2
PREAI
errNeilly, Mark; Tsim, Selina; Maclay, John; Bilancia, Rocco; Bibby, Anna; Gatheral, Timothy; Ionescu, Alina; Griffiths, Andrew; Aujayeb, Avinash; Rahman, Najib; Fallon, Janet; Craig, Christopher; Macdougall, Michelle; Corcoran, John; Panchal, Rakesh; Chetty, Mahendran; Lamote, Kevin; Cowell, Gordon; Miller, Crispin; Rintoul, Robert; Van Meerbeeck, Jan; Roche, Joshua; Macpherson, Alexandrea; Alexander, Laura; Roberts, Julie; Gourlay, Jacqui; Mcgarry, Joanne; Walker, Nicola; Blyth, Kevin
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errSave
What's new in pleural disease?
errTHORAX
IF7.7
err2023-10-17
err2
PREAI
errRintoul, Robert Campbell; Marciniak, Stefan John
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errSave
Hamlet.rt Trans: Prospective single-centre translational study evaluating liquid biomarkers of radiation response
errANNALS OF ONCOLOGY
IF65.4
err2023-10-01
err0
errOAAI
errDenholm, M.; Martin, H. W.; Roshan, A.; Miller, S.; Harden, G.; Towns, C.; Kadyan, S.; Mennea, P.; Munoz-Espin, D.; Rosenfeld, N.; Barnett, G. C.; Rintoul, R.; Coles, C. E.; Yang, H.; Jena, R.
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errSave
A tumor-promoting senescent secretome triggered by platinum chemotherapy exploits a targetable TGFβR1/Akt-mTOR axis in lung cancer
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errGonzalez-Gualda, Estela; Macias, David; Morsli, Samir; Martin, Jose Ezequiel; Ou, Hui-Ling; Denholm, Mary; Olan, Ioana; Hoffmann, Reuben; Dane, Mark; Veroutis, Dimitris; Medrano, Guillermo; Mulero, Francisca; Martins, Carla P.; Barbacid, Mariano; Gorgoulis, Vassilis; Korkola, James E.; Rassl, Doris M.; Doherty, Gary J.; Rintoul, Robert C.; Narita, Masashi; Munoz-Espin, Daniel
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errSave
Breath-based detection of lung cancer using exogenous volatile organic compound targeting β-glucuronidase in the tumor microenvironment
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errLabuschagne, Christiaan; Smith, Rob; Kumar, Neelam; Allsworth, Max; Boyle, Billy; Janes, Sam; Crosbie, Philip; Rintoul, Robert
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errSave
Diagnostic Accuracy of a Convolutional Neural Network Assessment of Solitary Pulmonary Nodules Compared With PET With CT Imaging and Dynamic Contrast-Enhanced CT Imaging Using Unenhanced and Contrast-Enhanced CT Imaging
errCHEST
IF8.6
err2023-02-01
err7
errOAAI
errWeir-McCall, Jonathan R.; Debruyn, Elise; Harris, Scott; Qureshi, Nagmi R.; Rintoul, Robert C.; Gleeson, Fergus, V; Gilbert, Fiona J.
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errSave
SARS-CoV-2-induced senescence as a potential therapeutic target
errEUROPEAN RESPIRATORY JOURNAL
IF21
err2022-07-01
err3
errOAAI
errDenholm, Mary; Rintoul, Robert C.; Munoz-Espin, Daniel
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errSave
Residual ctDNA after treatment predicts early relapse in patients with early-stage non-small cell lung cancer
errANNALS OF ONCOLOGY
IF65.4
err2022-05-01
err150
errOAAI
errGale, D.; Heider, K.; Ruiz-Valdepenas, A.; Hackinger, S.; Perry, M.; Marsico, G.; Rundell, V; Wulff, J.; Sharma, G.; Knock, H.; Castedo, J.; Cooper, W.; Zhao, H.; Smith, C. G.; Garg, S.; Anand, S.; Howarth, K.; Gilligan, D.; Harden, S., V; Rassl, D. M.; Rintoul, R. C.; Rosenfeld, N.
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errSave
Integrated genomics point to immune vulnerabilities in pleural mesothelioma (vol 11, 19138, 2021)
errSCIENTIFIC REPORTS
IF3.9
err2022-03-21
err0
errOAAI
errNastase, Anca; Mandal, Amit; Lu, Shir Kiong; Anbunathan, Hima; Morris-Rosendahl, Deborah; Zhang, Yu Zhi; Sun, Xiao-Ming; Gennatas, Spyridon; Rintoul, Robert C.; Edwards, Matthew; Bowman, Alex; Chernova, Tatyana; Benepal, Tim; Lim, Eric; Taylor, Anthony Newman; Nicholson, Andrew G.; Popat, Sanjay; Willis, Anne E.; MacFarlane, Marion; Lathrop, Mark; Bowcock, Anne M.; Moffatt, Miriam F.; Cookson, William O. C. M.
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errSave
Dynamic contrast-enhanced CT compared with positron emission tomography CT to characterise solitary pulmonary nodules: the SPUtNIk diagnostic accuracy study and economic modelling
errHEALTH TECHNOLOGY ASSESSMENT
IF4
err2022-03-01
err4
errOAAI
errGilbert, Fiona J.; Harris, Scott; Miles, Kenneth A.; Weir-McCall, Jonathan R.; Qureshi, Nagmi R.; Rintoul, Robert C.; Dizdarevic, Sabina; Pike, Lucy; Sinclair, Donald; Shah, Andrew; Eaton, Rosemary; Clegg, Andrew; Benedetto, Valerio; Hill, James E.; Cook, Andrew; Tzelis, Dimitrios; Vale, Luke; Brindle, Lucy; Madden, Jackie; Cozens, Kelly; Little, Louisa A.; Eichhorst, Kathrin; Moate, Patricia; McClement, Chris; Peebles, Charles; Banerjee, Anindo; Han, Sai; Poon, Fat Wui; Groves, Ashley M.; Kurban, Lutfi; Frew, Anthony J.; Callister, Matthew E.; Crosbie, Philip; Gleeson, Fergus, V; Karunasaagarar, Kavitasagary; Kankam, Osei; George, Steve
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Comparative accuracy and cost-effectiveness of dynamic contrast-enhanced CT and positron emission tomography in the characterisation of solitary pulmonary nodules
errTHORAX
IF7.7
err2021-12-09
err8
errOAAI
errGilbert, Fiona J.; Harris, Scott; Miles, Kenneth A.; Weir-McCall, Jonathan R.; Qureshi, Nagmi R.; Rintoul, Robert Campbell; Dizdarevic, Sabina; Pike, Lucy; Sinclair, Donald; Shah, Andrew; Eaton, Rosemary; Jones, Jeremy; Clegg, Andrew; Benedetto, Valerio; Hill, James; Cook, Andrew; Tzelis, Dimitrios; Vale, Luke; Brindle, Lucy; Madden, Jackie; Cozens, Kelly; Little, Louisa; Eichhorst, Kathrin; Moate, Patricia; McClement, Chris; Peebles, Charles; Banerjee, Anindo; Han, Sai; Poon, Fat-Wui; Groves, Ashley M.; Kurban, Lutfi; Frew, Anthony; Callister, Matthew E. J.; Crosbie, Phil A.; Gleeson, Fergus Vincent; Karunasaagarar, Kavitasagary; Kankam, Osei; George, Steve
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Research Directions

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