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Genome-wide CRISPR/Cas9 screen identifies etoposide response modulators associated with clinical outcomes in pediatric AML Nguyen, Nam H. K.; Rafiee, Roya; Tagmount, Abderrahmane; Sobh, Amin; Loguinov, Alex; Sosa, Angelica K. de Jesus; Elsayed, Abdelrahman H.; Gbadamosi, Mohammed; Seligson, Nathan; Cogle, Christopher R.; Rubnitz, Jeffery; Ribeiro, Raul; Downing, James; Cao, Xueyuan; Pounds, Stanley B.; Vulpe, Christopher D.; Lamba, Jatinder K. Share Save
Emi1 Maintains Genomic Integrity during Zebrafish Embryogenesis and Cooperates with p53 in Tumor Suppression Rhodes, Jennifer; Amsterdam, Adam; Sanda, Takaomi; Moreau, Lisa A.; McKenna, Keith; Heinrichs, Stefan; Ganem, Neil J.; Ho, Karen W.; Neuberg, Donna S.; Johnston, Adam; Ahn, Yebin; Kutok, Jeffery L.; Hromas, Robert; Wray, Justin; Lee, Charles; Murphy, Carly; Radtke, Ina; Downing, James R.; Fleming, Mark D.; MacConaill, Laura E.; Amatruda, James F.; Gutierrez, Alejandro; Galinsky, Ilene; Stone, Richard M.; Ross, Eric A.; Pellman, David S.; Kanki, John P.; Look, A. Thomas Share Save
Acute lymphoblastic leukemia displays a distinct highly methylated genome Hetzel, Sara; Mattei, Alexandra L.; Kretzmer, Helene; Qu, Chunxu; Chen, Xiang; Fan, Yiping; Wu, Gang; Roberts, Kathryn G.; Luger, Selina; Litzow, Mark; Rowe, Jacob; Paietta, Elisabeth; Stock, Wendy; Mardis, Elaine R.; Wilson, Richard K.; Downing, James R.; Mullighan, Charles G.; Meissner, Alexander Share Save
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Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia Umeda, Masayuki; Ma, Jing; Huang, Benjamin J.; Hagiwara, Kohei; Westover, Tamara; Abdelhamed, Sherif; Barajas, Juan M.; Thomas, Melvin E., III; Walsh, Michael P.; Song, Guangchun; Tian, Liqing; Liu, Yanling; Chen, Xiaolong; Kolekar, Pandurang; Quang Tran; Foy, Scott G.; Maciaszek, Jamie L.; Kleist, Andrew B.; Leonti, Amanda R.; Ju, Bengsheng; Easton, John; Wu, Huiyun; Valentine, Virginia; Valentine, Marcus B.; Liu, Yen-Chun; Ries, Rhonda E.; Smith, Jenny L.; Parganas, Evan; Iacobucci, Ilaria; Hiltenbrand, Ryan; Miller, Jonathan; Myers, Jason R.; Rampersaud, Evadnie; Rahbarinia, Delaram; Rusch, Michael; Wu, Gang; Inaba, Hiroto; Wang, Yi-Cheng; Alonzo, Todd A.; Downing, James R.; Mullighan, Charles G.; Pounds, Stanley; Babu, M. Madan; Zhang, Jinghui; Rubnitz, Jeffrey E.; Meshinchi, Soheil; Ma, Xiaotu; Klco, Jeffery M. Share Save
Experimental Models of SARS-CoV-2 Infection: Possible Platforms to Study COVID-19 Pathogenesis and Potential Treatments Pandamooz, Sareh; Jurek, Benjamin; Meinung, Carl-Philipp; Baharvand, Zahra; Shahem-Abadi, Alireza Sahebi; Haerteis, Silke; Miyan, Jaleel A.; Downing, James; Dianatpour, Mehdi; Borhani-Haghighi, Afshin; Salehi, Mohammad Saied Share Save
Integrative Genomic Analysis of Pediatric Myeloid-Related Acute Leukemias Identifies Novel Subtypes and Prognostic Indicators Fornerod, Maarten; Ma, Jing; Noort, Sanne; Liu, Yu; Walsh, Michael P.; Shi, Lei; Nance, Stephanie; Liu, Yanling; Wang, Yuanyuan; Song, Guangchun; Lamprecht, Tamara; Easton, John; Mulder, Heather L.; Yergeau, Donald; Myers, Jacquelyn; Kamens, Jennifer L.; Obeng, Esther A.; Pigazzi, Martina; Jarosova, Marie; Kelaidi, Charikleia; Polychronopoulou, Sophia; Lamba, Jatinder K.; Baker, Sharyn D.; Rubnitz, Jeffrey E.; Reinhardt, Dirk; Van den Heuvel-Eibrink, Marry M.; Locatelli, Franco; Hasle, Henrik; Klco, Jeffery M.; Downing, James R.; Zhang, Jinghui; Pounds, Stanley; Zwaan, C. Michel; Gruber, Tanja A. Share Save
A polygenic score for acute vaso-occlusive pain in pediatric sickle cell disease Rampersaud, Evadnie; Kang, Guolian; Palmer, Lance E.; Rashkin, Sara R.; Wang, Shuoguo; Bi, Wenjian; Alberts, Nicole M.; Anghelescu, Doralina; Barton, Martha; Birch, Kirby; Boulos, Nidal; Brandow, Amanda M.; Brooke, Russell John; Chang, Ti-Cheng; Chen, Wenan; Cheng, Yong; Ding, Juan; Easton, John; Hodges, Jason R.; Kanne, Celeste K.; Levy, Shawn; Mulder, Heather; Patel, Ashwin P.; Puri, Latika; Rosencrance, Celeste; Rusch, Michael; Sapkota, Yadav; Sioson, Edgar; Sharma, Akshay; Tang, Xing; Thrasher, Andrew; Wang, Winfred; Yao, Yu; Yasui, Yutaka; Yergeau, Donald; Hankins, Jane S.; Sheehan, Vivien A.; Downing, James R.; Estepp, Jeremie H.; Zhang, Jinghui; DeBaun, Michael; Wu, Gang; Weiss, Mitchell J. Share Save
Clinical Significance of novel Subtypes of Acute Lymphoblastic Leukemia in the Context of Minimal Residual Disease-Directed Therapy Jeha, Sima; Choi, John; Roberts, Kathryn G.; Pei, Deqing; Coustan-Smith, Elaine; Inaba, Hiroto; Rubnitz, Jeffrey E.; Ribeiro, Raul C.; Gruber, Tanja A.; Raimondi, Susana C.; Karol, Seth E.; Qu, Chunxu; Brady, Samuel W.; Gu, Zhaohui; Yang, Jun J.; Cheng, Cheng; Downing, James R.; Evans, Williams E.; Relling, Mary, V; Campana, Dario; Mullighan, Charles G.; Pui, Ching-Hon Share Save
Physiological and Pathological Factors Affecting Drug Delivery to the Brain by Nanoparticles Islam, Yamir; Leach, Andrew G.; Smith, Jayden; Pluchino, Stefano; Coxon, Christopher R.; Sivakumaran, Muttuswamy; Downing, James; Fatokun, Amos A.; Teixido, Meritxell; Ehtezazi, Touraj Share Save
Integrative network analysis reveals USP7 haploinsufficiency inhibits E-protein activity in pediatric T-lineage acute lymphoblastic leukemia (T-ALL) Shaw, Timothy I.; Dong, Li; Tian, Liqing; Qian, Chenxi; Liu, Yu; Ju, Bensheng; High, Anthony; Kavdia, Kanisha; Pagala, Vishwajeeth R.; Shaner, Bridget; Pei, Deqing; Easton, John; Janke, Laura J.; Porter, Shaina N.; Ma, Xiaotu; Cheng, Cheng; Pruett-Miller, Shondra M.; Choi, John; Yu, Jiyang; Peng, Junmin; Gu, Wei; Look, A. Thomas; Downing, James R.; Zhang, Jinghui Share Save
The Inclusion of a Matrix Metalloproteinase-9 Responsive Sequence in Self-assembled Peptide-based Brain-Targeting Nanoparticles Improves the Efficiency of Nanoparticles Crossing the Blood-Brain Barrier at Elevated MMP-9 Levels Islam, Yamir; Ehtezazi, Parinaz; Cashmore, Andrew; Marinsalda, Elena; Leach, Andrew G.; Coxon, Christopher R.; Fatokun, Amos A.; Sexton, Darren W.; Khan, Iftikhar; Zouganelis, Georgios; Downing, James; Pluchino, Stefano; Sivakumaran, Muttuswamy; Teixido, Meritxell; Ehtezazi, Touraj Share Save
St. Jude Cloud: A Pediatric Cancer Genomic Data-Sharing Ecosystem McLeod, Clay; Gout, Alexander M.; Zhou, Xin; Thrasher, Andrew; Rahbarinia, Delaram; Brady, Samuel W.; Macias, Michael; Birch, Kirby; Finkelstein, David; Sunny, Jobin; Mudunuri, Rahul; Orr, Brent A.; Treadway, Madison; Davidson, Bob; Ard, Tracy K.; Chiao, Arthur; Swistak, Andrew; Wiggins, Stephanie; Foy, Scott; Wang, Jian; Sioson, Edgar; Wang, Shuoguo; Michael, J. Robert; Liu, Yu; Ma, Xiaotu; Patel, Aman; Edmonson, Michael N.; Wilkinson, Mark R.; Frantz, Andrew M.; Chang, Ti-Cheng; Tian, Liqing; Lei, Shaohua; Islam, S. M. Ashiqul; Meyer, Christopher; Thangaraj, Naina; Tater, Pamella; Kandali, Vijay; Ma, Singer; Tuan Nguyen; Serang, Omar; McGuire, Irina; Robison, Nedra; Gentry, Darrell; Tang, Xing; Palmer, Lance E.; Wu, Gang; Suh, Ed; Tanner, Leigh; McMurry, James; Lear, Matthew; Pappo, Alberto S.; Wang, Zhaoming; Wilson, Carmen L.; Cheng, Yong; Meshinchi, Soheil; Alexandrov, Ludmil B.; Weiss, Mitchell J.; Armstrong, Gregory T.; Robison, Leslie L.; Yasui, Yutaka; Nichols, Kim E.; Ellison, David W.; Bangur, Chaitanya; Mullighan, Charles G.; Baker, Suzanne J.; Dyer, Michael A.; Miller, Geralyn; Newman, Scott; Rusch, Michael; Daly, Richard; Perry, Keith; Downing, James R.; Zhang, Jinghui Share Save
Pan-neuroblastoma analysis reveals age- and signature-associated driver alterations Brady, Samuel W.; Liu, Yanling; Ma, Xiaotu; Gout, Alexander M.; Hagiwara, Kohei; Zhou, Xin; Wang, Jian; Macias, Michael; Chen, Xiaolong; Easton, John; Mulder, Heather L.; Rusch, Michael; Wang, Lu; Nakitandwe, Joy; Lei, Shaohua; Davis, Eric M.; Naranjo, Arlene; Cheng, Cheng; Maris, John M.; Downing, James R.; Cheung, Nai-Kong V.; Hogarty, Michael D.; Dyer, Michael A.; Zhang, Jinghui Share Save
Development of Brain Targeting Peptide Based MMP-9 Inhibiting Nanoparticles for the Treatment of Brain Diseases with Elevated MMP-9 Activity Islam, Yamir; Khalid, Aneesa; Pluchino, Stefano; Sivakumaran, Muttuswamy; Teixido, Meritxell; Leach, Andrew; Fatokun, Amos A.; Downing, James; Coxon, Christopher; Ehtezazi, Touraj Share Save
CICERO: An accurate method for detecting complex and diverse driver fusions using cancer transcriptome sequencing (RNA-seq) data Tian, Liqing; Li, Yongjin; Edmonson, Michael N.; Zhou, Xin; Newman, Scott; McLeod, Clay; Liu, Yu; Tang, Bo; Rusch, Michael C.; Easton, John; Ma, Jing; Trull, Austyn; Michael, J. Robert; Thrasher, Andrew; Mullighan, Charles; Baker, Suzanne J.; Downing, James R.; Ellison, David W.; Zhang, Jinghui Share Save
CICERO: a versatile method for detecting complex and diverse driver fusions using cancer RNA sequencing data Tian, Liqing; Li, Yongjin; Edmonson, Michael N.; Zhou, Xin; Newman, Scott; McLeod, Clay; Thrasher, Andrew; Liu, Yu; Tang, Bo; Rusch, Michael C.; Easton, John; Ma, Jing; Davis, Eric; Trull, Austyn; Michael, J. Robert; Szlachta, Karol; Mullighan, Charles; Baker, Suzanne J.; Downing, James R.; Ellison, David W.; Zhang, Jinghui Share Save
A six-gene leukemic stem cell score identifies high risk pediatric acute myeloid leukemia (vol 74, pg152, 2020) Elsayed, Abdelrahman H.; Rafiee, Roya; Cao, Xueyuan; Raimondi, Susana; Downing, James R.; Ribeiro, Raul; Fan, Yiping; Gruber, Tanja A.; Baker, Sharyn; Klco, Jeffery; Rubnitz, Jeffrey E.; Pounds, Stanley; Lamba, Jatinder K. Share Save
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