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Stratified Medicine Paediatrics2-advancing precision medicine in paediatric cancer Vedi, Aditi; George, Sally; Jacques, Thomas; Cortes-Ciriano, Isidro; Hubank, Michael; Beggs, Andrew; Cheang, Maggie; Porta, Nuria; Hutchinson, Ciaran; Hopkins, Louise; Bukhari, Amina; Barfoot, Regan; Clifford, Steve; O'Connor, David; Ritzmann, Timothy; Burke, Amos; Anderson, John; Hargrave, Darren; Chesler, Louis Share Save
Genomic characterization of endocrine resistance in ER+HER2+breast cancers in the POETIC Trial Cheang, Maggie Chon U.; Zhu, Xixuan; Sipos, Orsolya; Alataki, Anastasia; Feldbauer, Mikayla; Lopez-Knowles, Elena; Tovey, Holly; Kilburn, Lucy; Sirven, Milana Bergamino; Patel, Dhrusti; Xiao, Hui; Maxwell, Perry; Skene, Anthony; Holcombe, Chris; Salto-Tellez, Manuel; Turner, Nicholas; Dodson, Andrew; Smith, Ian; Robertson, John; Bliss, Judith; Schuster, Gene; Salgado, Roberto; Dowsett, Mitch; Hoadley, Katherine A. Share Save
Longitudinal pro fi ling identi fi es co-occurring BRCA1/2 reversions, TP53BP1, RIF1 and PAXIP1 mutations in PARP inhibitor-resistant advanced breast cancer Harvey-Jones, E.; Raghunandan, M.; Robbez-Masson, L.; Magraner-Pardo, L.; Alaguthurai, T.; Yablonovitch, A.; Yen, J.; Xiao, H.; Brough, R.; Frankum, J.; Song, F.; Yeung, J.; Savy, T.; Gulati, A.; Alexander, J.; Kemp, H.; Starling, C.; Konde, A.; Marlow, R.; Cheang, M.; Proszek, P.; Hubank, M.; Cai, M.; Trendell, J.; Lu, R.; Liccardo, R.; Ravindran, N.; Llop-Guevara, A.; Rodriguez, O.; Balmana, J.; Lukashchuk, N.; Dorschner, M.; Drusbosky, L.; Roxanis, I.; Serra, V.; Haider, S.; Pettitt, S. J.; Lord, C. J.; Tutt, A. N. J. Share Save
Image-based multiplex immune profiling of cancer tissues: translational implications. A report of the International Immuno-oncology Biomarker Working Group on Breast Cancer Jahangir, Chowdhury Arif; Page, David B.; Broeckx, Glenn; Gonzalez, Claudia A.; Burke, Caoimbhe; Murphy, Clodagh; Reis-Filho, Jorge S.; Ly, Amy; Harms, Paul W.; Gupta, Rajarsi R.; Vieth, Michael; Hida, Akira, I; Kahila, Mohamed; Kos, Zuzana; van Diest, Paul J.; Verbandt, Sara; Thagaard, Jeppe; Khiroya, Reena; Abduljabbar, Khalid; Haab, Gabriela Acosta; Acs, Balazs; Adams, Sylvia; Almeida, Jonas S.; Alvarado-Cabrero, Isabel; Azmoudeh-Ardalan, Farid; Badve, Sunil; Baharun, Nurkhairul Bariyah; Bellolio, Enrique R.; Bheemaraju, Vydehi; Blenman, Kim R. M.; Fujimoto, Luciana Botinelly Mendonca; Burgues, Octavio; Chardas, Alexandros; Cheang, Maggie Chon U.; Ciompi, Francesco; Cooper, Lee A. D.; Coosemans, An; Corredor, German; Portela, Flavio Luis Dantas; Deman, Frederik; Demaria, Sandra; Dudgeon, Sarah N.; Elghazawy, Mahmoud; Fernandez-Martin, Claudio; Fineberg, Susan; Fox, Stephen B.; Giltnane, Jennifer M.; Gnjatic, Sacha; Gonzalez-Ericsson, Paula, I; Grigoriadis, Anita; Halama, Niels; Hanna, Matthew G.; Harbhajanka, Aparna; Hart, Steven N.; Hartman, Johan; Hewitt, Stephen; Horlings, Hugo M.; Husain, Zaheed; Irshad, Sheeba; Janssen, Emiel A. M.; Kataoka, Tatsuki R.; Kawaguchi, Kosuke; Khramtsov, Andrey, I; Kiraz, Umay; Kirtani, Pawan; Kodach, Liudmila L.; Korski, Konstanty; Akturk, Guray; Scott, Ely; Kovacs, Aniko; Laenkholm, Anne-Vibeke; Lang-Schwarz, Corinna; Larsimont, Denis; Lennerz, Jochen K.; Lerousseau, Marvin; Li, Xiaoxian; Madabhushi, Anant; Maley, Sai K.; Narasimhamurthy, Vidya Manur; Marks, Douglas K.; McDonald, Elizabeth S.; Mehrotra, Ravi; Michiels, Stefan; Kharidehal, Durga; Minhas, Fayyaz ul Amir Afsar; Mittal, Shachi; Moore, David A.; Mushtaq, Shamim; Nighat, Hussain; Papathomas, Thomas; Penault-Llorca, Frederique; Perera, Rashindrie D.; Pinard, Christopher J.; Pinto-Cardenas, Juan Carlos; Pruneri, Giancarlo; Pusztai, Lajos; Rajpoot, Nasir Mahmood; Rapoport, Bernardo Leon; Rau, Tilman T.; Ribeiro, Joana M.; Rimm, David; Vincent-Salomon, Anne; Saltz, Joel; Sayed, Shahin; Hytopoulos, Evangelos; Mahon, Sarah; Siziopikou, Kalliopi P.; Sotiriou, Christos; Stenzinger, Albrecht; Sughayer, Maher A.; Sur, Daniel; Symmans, Fraser; Tanaka, Sunao; Taxter, Timothy; Tejpar, Sabine; Teuwen, Jonas; Thompson, E. Aubrey; Tramm, Trine; Tran, William T.; van Der Laak, Jeroen; Verghese, Gregory E.; Viale, Giuseppe; Wahab, Noorul; Walter, Thomas; Waumans, Yannick; Wen, Hannah Y.; Yang, Wentao; Yuan, Yinyin; Bartlett, John; Loibl, Sibylle; Denkert, Carsten; Savas, Peter; Loi, Sherene; Stovgaard, Elisabeth Specht; Salgado, Roberto; Gallagher, William M.; Rahman, Arman Share Save
Identifying new biological subgroups of triple-negative breast cancer using next-generation integrative clustering pipeline Zhu, X.; Bayani, J.; Dewan, M.; Tovey, H.; Kilburn, L.; Taylor, K.; Banerji, J.; Toms, C.; Sadanandam, A.; Barrett-Lee, P. J.; Bliss, J.; Cameron, D. A.; Bartlett, J. M. S.; Cheang, M. C. U. Share Save
Pitfalls in machine learning-based assessment of tumor-infiltrating lymphocytes in breast cancer: a report of the international immuno-oncology biomarker working group Thagaard, Jeppe; Broeckx, Glenn; Page, David B.; Jahangir, Chowdhury Arif; Verbandt, Sara; Kos, Zuzana; Gupta, Rajarsi; Khiroya, Reena; Abduljabbar, Khalid; Acosta Haab, Gabriela; Acs, Balazs; Akturk, Guray; Almeida, Jonas S.; Alvarado-Cabrero, Isabel; Amgad, Mohamed; Azmoudeh-Ardalan, Farid; Badve, Sunil; Baharun, Nurkhairul Bariyah; Balslev, Eva; Bellolio, Enrique R.; Bheemaraju, Vydehi; Blenman, Kim R. M.; Botinelly Mendonca Fujimoto, Luciana; Bouchmaa, Najat; Burgues, Octavio; Chardas, Alexandros; Cheang, Maggie U.; Ciompi, Francesco; Cooper, Lee A. D.; Coosemans, An; Corredor, German; Dahl, Anders B.; Dantas Portela, Flavio Luis; Deman, Frederik; Demaria, Sandra; Dore Hansen, Johan; Dudgeon, Sarah N.; Ebstrup, Thomas; Elghazawy, Mahmoud; Fernandez-Martin, Claudio; Fox, Stephen B.; Gallagher, William M.; Giltnane, Jennifer M.; Gnjatic, Sacha; Gonzalez-Ericsson, Paula, I; Grigoriadis, Anita; Halama, Niels; Hanna, Matthew G.; Harbhajanka, Aparna; Hart, Steven N.; Hartman, Johan; Hauberg, Soren; Hewitt, Stephen; Hida, Akira, I; Horlings, Hugo M.; Husain, Zaheed; Hytopoulos, Evangelos; Irshad, Sheeba; Janssen, Emiel A. M.; Kahila, Mohamed; Kataoka, Tatsuki R.; Kawaguchi, Kosuke; Kharidehal, Durga; Khramtsov, Andrey, I; Kiraz, Umay; Kirtani, Pawan; Kodach, Liudmila L.; Korski, Konstanty; Kovacs, Aniko; Laenkholm, Anne-Vibeke; Lang-Schwarz, Corinna; Larsimont, Denis; Lennerz, Jochen K.; Lerousseau, Marvin; Li, Xiaoxian; Ly, Amy; Madabhushi, Anant; Maley, Sai K.; Manur Narasimhamurthy, Vidya; Marks, Douglas K.; McDonald, Elizabeth S.; Mehrotra, Ravi; Michiels, Stefan; Minhas, Fayyaz ul Amir Afsar; Mittal, Shachi; Moore, David A.; Mushtaq, Shamim; Nighat, Hussain; Papathomas, Thomas; Penault-Llorca, Frederique; Perera, Rashindrie D.; Pinard, Christopher J.; Pinto-Cardenas, Juan Carlos; Pruneri, Giancarlo; Pusztai, Lajos; Rahman, Arman; Rajpoot, Nasir Mahmood; Rapoport, Bernardo Leon; Rau, Tilman T.; Reis-Filho, Jorge S.; Ribeiro, Joana M.; Rimm, David; Roslind, Anne; Vincent-Salomon, Anne; Salto-Tellez, Manuel; Saltz, Joel; Sayed, Shahin; Scott, Ely; Siziopikou, Kalliopi P.; Sotiriou, Christos; Stenzinger, Albrecht; Sughayer, Maher A.; Sur, Daniel; Fineberg, Susan; Symmans, Fraser; Tanaka, Sunao; Taxter, Timothy; Tejpar, Sabine; Teuwen, Jonas; Thompson, E. Aubrey; Tramm, Trine; Tran, William T.; van Der Laak, Jeroen; van Diest, Paul J.; Verghese, Gregory E.; Viale, Giuseppe; Vieth, Michael; Wahab, Noorul; Walter, Thomas; Waumans, Yannick; Wen, Hannah Y.; Yang, Wentao; Yuan, Yinyin; Zin, Reena Md; Adams, Sylvia; Bartlett, John; Loibl, Sibylle; Denkert, Carsten; Savas, Peter; Loi, Sherene; Salgado, Roberto; Specht Stovgaard, Elisabeth Share Save
Molecular profiling of aromatase inhibitor sensitive and resistant ER+HER2-postmenopausal breast cancers Schuster, Eugene F.; Lopez-Knowles, Elena; Alataki, Anastasia; Zabaglo, Lila; Folkerd, Elizabeth; Evans, David; Sidhu, Kally; Cheang, Maggie Chon U.; Tovey, Holly; Salto-Tellez, Manuel; Maxwell, Perry; Robertson, John; Smith, Ian; Bliss, Judith M.; Dowsett, Mitch Share Save
The proteomic landscape of soft tissue sarcomas Burns, Jessica P.; Wilding, Christopher; Krasny, Lukas; Zhu, Xixuan; Chadha, Madhumeeta; Tam, Yuen Bun; Hari, P. S. H.; Mahalingam, Aswanth; Lee, Alexander T. J.; Arthur, Amani; Guljar, Nafia; Perkins, Emma; Pankova, Valeriya; Jenks, Andrew; Djabatey, Vanessa; Szecsei, Cornelia; McCarthy, Frank; Ragulan, Chanthirika; Milighetti, Martina I.; Roumeliotis, Theodoros; Crosier, Stephen; Finetti, Martina S.; Choudhary, Jyoti; Judson, Ian; Fisher, Cyril F.; Schuster, Eugene; Sadanandam, Anguraj W.; Chen, Tom; Williamson, Daniel; Thway, Khin L.; Jones, Robin; Cheang, Maggie C. U. H.; Huang, Paul Share Save
Histopathological and molecular immune landscape and DNA damage response signatures to predict response to carboplatin and docetaxel in TNT trial TNBC cohort Tovey, Holly; Sipos, Orsolya; Hoadley, Katherine A.; Parker, Joel S.; Quist, Jelmar; Kernaghan, Sarah; Kilburn, Lucy; Salgado, Roberto; Loi, Sherene; Kennedy, Richard D.; Roxanis, Ioannis; Gazinska, Patrycja; Pinder, Sarah E.; Bliss, Judith; Perou, Charles M.; Haider, Syed; Tutt, Andrew; Grigoriadis, Anita; Cheang, Maggie Chon U. Share Save
Deconstructing the molecular characteristics of ER+HER2+early breast cancer in the POETIC trial using multiplex immunofluorescence and gene expression profiles Zhu, Xixuan; Xiao, Hui; Lopez-Knowles, Elena; Sirven, Milana A. Bergamino; Alataki, Anastasia; Maxwell, Perry; Tovey, Holly; Kilburn, Lucy; Holcombe, Chris; Skene, Anthony; Smith, Ian; Robertson, John; Hoadley, Katherine A.; Salgado, Roberto; Bliss, Judith; Turner, Nicholas; Salto-Tellez, Manuel; Schuster, Gene; Dowsett, Mitch; Cheang, Maggie Chon U. Share Save
Immune cell infiltration associated with poor anti-proliferative response to aromatase inhibitors in postmenopausal women with primary ER-positive HER2-negative breast cancer Alataki, Anastasia; Schuster, Gene; Zabaglo, Lila; Maxwell, Perry; Lopez-Knowles, Elena; Folkerd, Elizabeth; Evans, David; Sidhu, Kally; Tovey, Holly; Turner, Nicholas; Johnston, Stephen; Cheang, Maggie Chon U.; Robertson, John; Salto-Tellez, Manuel; Smith, Ian; Bliss, Judith; Dowsett, Mitch Share Save
Low plasma estradiol, low expression of estrogen responsive genes and TP53 mutations are associated with poor anti-proliferative response to aromatase inhibitors Schuster, Eugene F.; Lopez-Knowles, Elena; Alataki, Anastasia; Zabaglo, Lila; Folkerd, Elizabeth; Evans, David; Sidhu, Kally; Tovey, Holly; Maxwell, Perry; Turner, Nicholas; Johnston, Stephen; Salto-Tellez, Manuel; Cheang, Maggie Chon U.; Robertson, John; Smith, Ian; Bliss, Judith; Dowsett, Mitch Share Save
Multi-parametric algorithm integrating on-treatment Ki67 value and standard clinicopathological variables to predict risk of recurrences for women > 70 years old with early ER+HER2-tumours in POETIC trial Cheang, Maggie Chon U.; Dewan, Monisha; Kilburn, Lucy; Morani, Gabriele; Zabaglo, Lila; Sidhu, Kally; Tovey, Holly; Zhu, Xixuan; Holcombe, Chris; Skene, Anthony; Smith, Ian; Robertson, John; Ring, Alistair; Turner, Nicholas; Bliss, Judith; Dowsett, Mitch Share Save
Relationship between ER expression by IHC or mRNA with Ki67 response to aromatase inhibition: a POETIC study Lopez-Knowles, Elena; Detre, Simone; Hills, Margaret; Schuster, Eugene F.; Cheang, Maggie C. U.; Tovey, Holly; Kilburn, Lucy S.; Bliss, Judith M.; Robertson, John; Mallon, Elizabeth; Skene, Anthony; Evans, Abigail; Smith, Ian; Dowsett, Mitch Share Save
HER2-enriched subtype and novel molecular subgroups drive aromatase inhibitor resistance and an increased risk of relapse in early ER+/HER2+ breast cancer Bergamino, Milana A.; Lopez-Knowles, Elena; Morani, Gabriele; Tovey, Holly; Kilburn, Lucy; Schuster, Eugene F.; Alataki, Anastasia; Hills, Margaret; Xiao, Hui; Holcombe, Chris; Skene, Anthony; Robertson, John F.; Smith, Ian E.; Bliss, Judith M.; Dowsett, Mitch; Cheang, Maggie C. U. Share Save
Overlapping molecular features (proliferation, immune signatures andTP53mutations) associated with palbociclib resistance inER+HER2-primary breast cancer Schuster, Eugene F.; Xiao, Hui; Cheang, Maggie; Lopez-Knowles, Elena; Kilburn, Lucy; Korchina, Viktoriya; Salvi, Sejal; Jacobs, Samuel A.; Finnigan, Melanie; Wheeler, David A.; Puhalla, Shannon; Muzny, Donna; Doddapaneni, Harsha; Pogue-Geile, Katherine; Liu, Yuan; Bliss, Judith; Johnston, Stephen; Dowsett, Mitch; Rimawi, Mothaffar Share Save
A novel combination of a 2 gene score & TIL as a predictive Biomarker for responders to novel therapies in Indian TNBC - A population with greater proportion of TNBCs Korlimarla, Aruna; Hari, P. S.; Prabhu, Jyothi S.; Ragulan, Chantirika; Diwakar, Ravi B.; Apachu, Sandhya; Cheang, Maggie; Kumar, Rekha V.; Srinath, B. S.; Sridhar, T. S.; Rajarajan, Savitha; Alexander, Annie; Sadanandam, Anguraj Share Save
Impact of using cross-platform gene expression profiling technologies and computational methods for intrinsic breast cancer subtyping in PALOMA-2 and PALLET Cheang, Maggie; Dowsett, Mitch; Rimawi, Mothaffar; Johnston, Stephen; Jacobs, Samuel; Bliss, Judith; Pogue-Geile, Katherine; Kilburn, Lucy; Zhu, Zhou; Schuster, Eugene F.; Xiao, Hui; Swaim, Lisa; Deng, Shibing; Lu, Dongrui R.; Gauthier, Eric; Tursi, Jennifer; Slamon, Dennis J.; Rugo, Hope S.; Finn, Richard S.; Liu, Yuan Share Save
HER2-enriched subtype and novel molecular subgroups drive aromatase inhibitor resistance and an increased risk of relapse in early ER+/HER2+breast cancer Sirven, Milana A. Bergamino; Lopez-Knowles, Elena; Morani, Gabriele; Tovey, Holly; Kilburn, Lucy; Holcombe, Chris; Skene, Anthony; Smith, Ian; Robertson, John; Schuster, Gene; Bliss, Judith M.; Dowsett, Mitch; Cheang, Maggie C. U. Share Save
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